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We Built Our Own Salesforce in Months. Here's Why We're Cancelling the $600K Contract | Curative CEO

Fred Turner is the Founder and CEO @ Curative, one of the wildest stories in tech. Fred scaled a COVID testing business from $0 to $5BN in revenue and took the team from 7 to 7,000 employees in just 9 months. They did over 206,000 COVID tests in a single day and signed contracts in the 100s of $Ms with several of the largest states. Today, Curative is a unicorn health insurance business taking on the incumbents for one of the largest markets in healthcare. ----------------------------------------------- Timestamps: 00:00 Intro 01:07 – Meet Fred Turner: thrill of winning vs. fear of losing 02:01 – Why he couldn't have built this business in the UK 03:40 – From cattle genetics to sepsis to Covid (the origin story) 07:54 – Pivoting into human diagnostics and at-home STD testing 14:43 – Founding Curative on a sepsis thesis, before Covid changed everything 18:44 – Covid hits: pivoting overnight into mass testing 27:03 – Building an "orthogonal supply chain" to scale testing 10x 30:44 – $5B in revenue, brutal margins, and losing money on vaccines 35:32 – The pivot to health insurance after Covid winds down 41:39 – How AI agents replaced entire back-office departments 45:48 – Is SaaS dead? Cutting Salesforce and 80% of SaaS spend 1:13:06 – Subcritical: building a fundamentally safer nuclear reactor ---------------------------------------------------------------------------------------------- Subscribe on Spotify: https://open.spotify.com/show/3j2KMcZTtgTNBKwtZBMHvl?si=85bc9196860e4466 Subscribe on Apple Podcasts: https://podcasts.apple.com/us/podcast/the-twenty-minute-vc-20vc-venture-capital-startup/id958230465 Follow Harry Stebbings on X: https://twitter.com/HarryStebbings Follow Fred Turner on X: https://twitter.com/FredTurnerBio Follow 20VC on Instagram: https://www.instagram.com/20vchq Follow 20VC on TikTok: https://www.tiktok.com/@20vc_tok Visit our Website: https://www.20vc.com Subscribe to our Newsletter: https://www.thetwentyminutevc.com/contact ----------------------------------------------- #20vc #harrystebbings #curative #founder #ceo

Fred TurnerguestHarry Stebbingshost
Jul 18, 20261h 29mWatch on YouTube ↗

At a glance

WHAT IT’S REALLY ABOUT

Curative’s whiplash pivots: COVID scale, insurer reinvention, AI overhaul

  1. Turner traces a founder journey of repeated pivots—cattle genomics to human diagnostics to sepsis—before a near-death shutdown set the stage for Curative’s COVID testing break out.
  2. Curative seized early-pandemic testing demand by rapidly acquiring lab capability, winning government contracts, and scaling to 206,000 tests/day and ~7,000 employees in nine months.
  3. The COVID business produced $5B in revenue but had volatile economics—highly profitable during surges, loss-making during demand lulls due to fixed capacity requirements.
  4. As COVID demand faded, Curative chose health insurance as the next giant market, arguing payers drive healthcare behavior and consolidation makes current negotiations inefficient.
  5. Turner claims AI agents are eliminating or radically shrinking insurance back-office work and enabling major SaaS replacement, while raising new questions about labor displacement and governance.

IDEAS WORTH REMEMBERING

5 ideas

Market size can force the right pivot faster than technology can.

The cow-testing business hit a Series A ceiling once investors did the TAM math, pushing the team to reuse core DNA testing capabilities in larger human-health markets.

Sepsis innovation fails if workflows don’t trigger the test in time.

Turner argues community hospitals often don’t suspect sepsis early enough, so better diagnostics alone don’t improve outcomes unless operational adoption is solved.

In crises, scaling requires abandoning “efficient” industry defaults.

Curative outscaled incumbents by rebuilding the testing stack for 10× demand and using an “orthogonal supply chain” (alternative consumables, filter plates over magnetic beads) rather than competing for the same constrained inputs.

Government contract structure can become your financing mechanism.

LA’s daily invoicing with next-day checks and other large public contracts provided the cash flow that enabled rapid expansion and even funded a $27M lab buyout via forward revenue.

Pandemic businesses can be huge yet structurally unstable.

Testing economics swung from strong margins at peak utilization to losses in troughs because capacity had to stay staffed and ready for the next surge.

WORDS WORTH SAVING

5 quotes

And the company went from about seven to 7,000 employees in, in those first nine months.

Fred Turner

I sold that license to a company in San Diego for $150,000, uh, to pay some of the creditors. And then five months later, acquired a company in Southern California to get the same license for 27 million. So timing is everything.

Fred Turner

So we built what we called, uh, an orthogonal supply chain, which is just basically a fancy way of saying, we don't use the things other people use.

Fred Turner

We have now built in-house an agent that runs on, on Claude that does this end to end... we're now averaging about 12 hours turnaround time for credentialing somebody, and it costs us about 20 cents.

Fred Turner

I think today the current gen models can do every back office task we have at Curative. It's just a matter of deploying them, like getting them set up, getting them configured, having the right policies.

Fred Turner

UK vs Silicon Valley startup capital culturePivoting from agtech to human diagnosticsSepsis outcomes and community-hospital bottlenecksCOVID test scaling and government contractingOrthogonal supply chain strategyCOVID unit economics: surge vs dip profitabilityPivot to health insurance and payer powerAI agents for credentialing, claims, underwriting, contracting“SaaS is dead” and internal tool buildingAgent supervision, trust, and workforce displacementNuclear energy amplifier and subcritical reactorsRegulation as the real bottleneck (healthcare, nuclear, Europe)

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