Skip to content
a16za16z

AI Is Coming For These 3 Industries In 2026 (a16z Big Ideas)

AI is reshaping the foundations of industry, finance, and enterprise software. In part two of Big Ideas 2026, we explore three shifts redefining how systems scale. Ryan McEntush breaks down the rise of the electro-industrial stack and the challenge of building a U.S. ecosystem to power modern industry. Angela Strange explains why financial services and insurance are reaching a tipping point, where replacing legacy systems unlocks unified data, parallel workflows, and major margin gains. Sarah Wang looks ahead to a dynamic agent layer that overtakes traditional systems of record. Together, these ideas point to a clear shift: advantage moves from software to systems, from fragmented plumbing to AI-native platforms, and from static records to agent-driven execution. Timestamps: 0:00 Big Ideas 2026 0:36 The Electro-Industrial Stack (Ryan McEntush) 0:56 America vs. China: Industrial Ecosystems 2:12 Blending Talent and Building Prestige 3:56 The Importance of Supply Chains 4:22 A Turning Point in Financial Services (Angela Strange) 4:49 AI-Native Infrastructure and System Unification 5:35 Expanding Categories and 10x Winners 6:24 Why Now? The Drivers of Change 7:25 Opportunities for Early Adopters 8:06 The Power of Unified Data 8:55 Call to Founders: The Opportunity in 2026 9:23 The Dynamic Agent Layer (Sarah Wang) 9:50 From Systems of Record to Dynamic Agents 10:28 The ITSM Example and Agent Layer Value 11:19 The Race for Better Solutions Resource: Follow Ryan on X: https://twitter.com/rmcentush Follow Angela on X: https://twitter.com/astrange Follow Sarah Wang on X: https://twitter.com/sarahdingwang Read more all of our 2026 Big Ideas Part 1: https://a16z.com/newsletter/big-ideas-2026-part-1 Part 2: https://a16z.com/newsletter/big-ideas-2026-part-2 Part 3: https://a16z.com/newsletter/big-ideas-2026-part-3 Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends! Find a16z on X: https://twitter.com/a16z Find a16z on LinkedIn: https://www.linkedin.com/company/a16z Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711 Follow our host: https://x.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see [a16z.com/disclosures](http://a16z.com/disclosures).

Erik TorenberghostRyan McEntushguestAngela StrangeguestSarah Wangguest
Dec 26, 202512mWatch on YouTube ↗

CHAPTERS

  1. Big Ideas 2026: Three AI-driven shifts across industry, finance, and enterprise software

    Erik Torenberg frames the episode as part two of a16z’s 2026 Big Ideas, featuring three investors’ forecasts. The throughline is AI and software reshaping foundational layers of the economy: how we build things, how money moves, and how work gets done inside companies.

  2. The electro-industrial stack: electrified components become the new industrial core

    Ryan McEntush introduces the “electro-industrial stack” as the next industrial evolution happening inside the machines themselves. He ties together EVs, drones, data centers, and modern manufacturing around shared building blocks like batteries, power electronics, compute, and motors.

  3. America vs. China: technology parity, ecosystem gap

    McEntush argues the U.S. can match China’s industrial technologies, but the larger challenge is scaling them economically. China’s advantage is the density and speed of its end-to-end industrial ecosystem—suppliers, materials, and enabling institutions.

  4. How to build it in the U.S.: blend talent, co-locate, and rebuild industrial prestige

    To compete, McEntush emphasizes combining Silicon Valley software velocity with industrial veterans’ domain knowledge. He also stresses tight coupling between engineering and manufacturing and elevating the mission to attract top talent.

  5. Supply chains as strategic leverage in an AI-powered world

    McEntush closes by emphasizing that reshoring and owning supply chains for key components will determine economic and military power over the long run. As AI increases automation and industrial capability, control over these inputs becomes more consequential.

  6. Financial services & insurance tipping point: legacy risk now exceeds change risk

    Angela Strange predicts a dramatic turning point where major institutions let legacy contracts lapse and adopt AI-native competitors. The catalyst is new infrastructure that unifies data across cores and external/unstructured sources into a new system of record.

  7. What changes for operators: parallel workflows, expanded platforms, and bigger winners

    Strange outlines three major impacts once AI-native infrastructure takes hold. Workflows become parallelized, risk/compliance categories converge into broader platforms, and the biggest winners become much larger by absorbing labor and expanding category scope.

  8. Why now: mainframes near limits, AI revenue upside, and credible AI-first vendors

    Strange argues the timing is different now because legacy cores are strained, AI creates immediate upside, and the vendor landscape finally includes viable, re-architected AI-first platforms. Entrepreneurs who are both deeply technical and domain-native are building real replacements.

  9. Early adopters gain compounding advantages through unified data

    Strange highlights how early adopters can develop reputations as forward-thinking partners and quickly outpace slower rivals. Unified data layers enable better customer experiences and operational leverage, translating into large margin improvements in some business lines.

  10. Call to founders: modernize banking/insurance plumbing in 2026

    Strange ends with a builder-focused message: the market is ready and the opportunity is enormous for AI-first infrastructure. Founders with deep curiosity about “archaic” processes can build faster than ever and sell into urgent demand.

  11. Systems of record under threat: dynamic agents collapse intent-to-execution

    Sarah Wang predicts systems of record will lose primacy as agents can execute tasks directly from user intent. She frames this as the first credible 10x disruption after prior SaaS waves failed to dislodge systems of record with UI improvements alone.

  12. ITSM as the concrete wedge: from tickets to near-instant fulfillment

    Using IT service management, Wang illustrates how agents can transform slow, form-based workflows into rapid execution. Advances in LLMs let systems interpret requests, route them to workflows, and complete actions reliably within existing stacks.

  13. Where value accrues: foundation models matter, but the agent layer compounds

    Wang distinguishes the enduring value of the foundation model layer from the compounding advantage of the agent layer closest to the user. The agent layer captures user context and preferences, which can become defensible over time.

  14. Competitive dynamics: fast iteration rewards new entrants, 2026 as the crossover year

    Wang argues the market is moving at weekly/daily improvement cycles, favoring teams that ship quickly and deliver reliable outcomes. She points to early examples of agent-native tools outperforming agents bolted onto iconic platforms, and predicts 2026 is when agents overtake systems of record.

Get more out of YouTube videos.

High quality summaries for YouTube videos. Accurate transcripts to search & find moments. Powered by ChatGPT & Claude AI.

Add to Chrome