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Jay Shetty PodcastWORLDS TOP OBGYN: #1 Hormone Problem Impacting MILLIONS of Women (This is How You REVERSE it!)
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At a glance
WHAT IT’S REALLY ABOUT
OBGYN explains PCOS and endometriosis causes, symptoms, and solutions today
- Dr. Aliabadi frames a “fertility crisis” in which many cases labeled unexplained infertility are actually undiagnosed PCOS or endometriosis.
- She defines PCOS as a hormonal-metabolic-inflammatory-neurologic condition and teaches the diagnostic rule of meeting two of three criteria: ovulatory dysfunction, characteristic ovarian morphology/high AMH, and hyperandrogenism symptoms.
- PCOS management is presented as addressing four pillars—insulin resistance, hormonal/androgen imbalance, chronic inflammation, and brain effects—using lifestyle changes, insulin-sensitizing tools (e.g., metformin/GLP-1s), and selective hormonal therapy rather than birth control alone.
- She defines endometriosis as a chronic inflammatory neuroimmune disorder causing debilitating pain and central nervous system sensitization, emphasizing it can be diagnosed clinically and treated first with hormonal suppression and, when needed, expert excision surgery.
- Actionable fertility guidance includes early symptom recognition, AMH/ultrasound-based screening, partner semen analysis, targeted workups (HSG/anatomy), and proactive suppression/egg-freezing considerations to protect ovarian reserve.
IDEAS WORTH REMEMBERING
5 ideasMany “unexplained infertility” cases may be missed PCOS or endometriosis.
Aliabadi claims large proportions of PCOS (≈75%) and endometriosis (≈90%+) go undiagnosed, pushing patients into the unexplained category when the underlying drivers are treatable or manageable.
PCOS diagnosis is pattern-based: you only need 2 of 3 criteria.
She stresses irregular/absent ovulation, PCOS ovarian morphology (or high egg count/AMH), and hyperandrogen signs (acne, hirsutism, hair loss) can combine in multiple ways—so “no cysts/no high testosterone/no irregular periods” doesn’t rule it out.
Insulin resistance is positioned as the core PCOS “first domino.”
She explains that insulin resistance raises insulin, promotes visceral fat/inflammation, and stimulates ovarian androgen production—creating a feedback loop that disrupts ovulation and mood/energy.
Small, consistent behavior changes can meaningfully improve insulin sensitivity.
Her practical baseline includes lowering carb load and taking a 10–20 minute walk after meals to help muscles pull glucose from blood, alongside regular cardio and broader exercise.
Medications for metabolic PCOS should be planned for sustainability, not quick weight loss.
She describes GLP-1s as useful for PCOS because they improve insulin regulation and weight, but warns that stopping without ongoing insulin-resistance support (e.g., metformin and lifestyle) often leads to rebound weight gain.
WORDS WORTH SAVING
5 quotesI want to scream in this mic and say, "Doctors, healthcare providers, listen to your patients."
— Dr. Thaïs Aliabadi
You know, your genetics load the gun, but your lifestyle pulls the trigger.
— Dr. Thaïs Aliabadi
Painful periods are not normal.
— Dr. Thaïs Aliabadi
Will you believe me if I told you that every single patient, when I diagnose them in my clinic with endometriosis or when I wake them up from surgery and I tell them the stage of their endometriosis, the first thing they do, they cry and they say, "I feel validated"?
— Dr. Thaïs Aliabadi
People grab that mic for nonsense. Give me that mic for 20 minutes only. Let me tell women what they deserve to know.
— Dr. Thaïs Aliabadi
SPEAKERS
Dr. Thaïs Aliabadi
guestOB-GYN and women’s health specialist known for clinical work on PCOS, endometriosis, and fertility care.
Jay Shetty
hostHost of the On Purpose podcast and wellness communicator/interviewer.
High quality AI-generated summary created from speaker-labeled transcript.
