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The Joe Rogan ExperienceThe Joe Rogan Experience

Joe Rogan Experience #2060 - Gary Brecka

Gary Brecka is a human biologist and co-founder of 10X Health System.

Joe RoganhostGary Breckaguest
Jun 27, 20242h 17mWatch on YouTube ↗

Summaries, chapters, transcripts, and FAQs on this page are made by uListen, not YouTube.

Partial transcript

0:00 – 1:57

Dana White’s health turnaround and the “life expectancy wake-up call”

Narrator 0:00 (drum beat plays) Joe Rogan podcast. Check it out. The Joe Rogan Experience.

Joe Rogan 0:06 Train by day, Joe Rogan podcast by night. All day. (instrumental music plays)

Gary Brecka 0:12 Fired up.

Joe Rogan 0:13 What's up? How are you, man?

Gary Brecka 0:13 I'm doing amazing, man.

Joe Rogan 0:14 Thanks for being here.

Gary Brecka 0:15 Dude, you're welcome.

Joe Rogan 0:16 And thank ... Thanks for saving Dana White's life.

Gary Brecka 0:19 (laughs)

Joe Rogan 0:19 (laughs) 'Cause th- that's what he credits. He credits talking to you and taking your advice as completely changing his life, and now he feels infinitely better.

Gary Brecka 0:27 Yeah. I mean, he did a lot of the work himself.

Joe Rogan 0:29 Well, he had to, but you had to tell him what to do. But luckily, he listened.

Gary Brecka 0:33 Yeah. I mean, I think, I think giving him a life expectancy just kind of validated it for him, it just really put it in his face.

Joe Rogan 0:41 Uh-huh.

Gary Brecka 0:41 And, you know, 'cause that's something you can calculate. He's like, "Okay, well, I'm 53 now. 63 doesn't seem that far off."

Joe Rogan 0:48 Right.

Gary Brecka 0:48 You know?

Joe Rogan 0:48 A lot of like high-stress individuals that don't take care of themselves, their ticker checks out-

Gary Brecka 0:55 Yeah.

Joe Rogan 0:55 ... around 65-

Gary Brecka 0:56 It, it ... I mean-

Joe Rogan 0:57 67.

Gary Brecka 0:58 Yeah.

Joe Rogan 0:59 That's pretty standard.

Gary Brecka 0:59 It just takes its toll. I mean and-

Joe Rogan 1:01 Yeah.

Gary Brecka 1:01 And the funny thing is, you know, uh, when you go back and you look at the, the pictures of him prior to-

Joe Rogan 1:08 Oh, yeah.

Gary Brecka 1:09 ... he does kind of look like he was about to pop, you know?

Joe Rogan 1:12 It's not good.

Gary Brecka 1:13 (laughs)

Joe Rogan 1:13 Yeah. He had a big old moon face, and he has, you know-

Gary Brecka 1:16 Veins up on the forehead and the veins out of the side of the neck.

Joe Rogan 1:20 He's getting thick. What was the like f- first of all, how did he meet you? How did this, this come about, and like how did the conversation start?

Gary Brecka 1:27 So, we have a mutual friend, um, named Kari Kasem. Y- if you remember, uh, Casey Kasem-

Joe Rogan 1:33 Yeah, I know Kari.

Gary Brecka 1:34 ... weekly top 40.

Joe Rogan 1:34 I worked with her back in the day in the early UFCs.

Gary Brecka 1:36 Okay. So, um, uh, you know, I, I recently met, uh, Kari, and she had kind of a life-changing experience as well. You know, if you know anything about her journey with Lyme disease and chronic viral infection, I mean, she really, she really struggled and ended up healing herself. And, um, she took the same test that, that, that Dana White did. It was life-changing for her, and she was like, "Look-"

1:57 – 3:56

What the genetic methylation test measures (and why it’s foundational)

Joe Rogan 1:57 What is this test?

Gary Brecka 1:58 It's a genetic test. It looks at, um, genetic methylation pathways. So-

Joe Rogan 2:03 Methylation pathways?

Gary Brecka 2:05 Methylation pathways.

Joe Rogan 2:05 What's that word mean?

Gary Brecka 2:07 So, think about it like this. Um, you know, we pull crude oil out of the ground, right?

Joe Rogan 2:11 Mm-hmm.

Gary Brecka 2:11 But, but you can't put crude oil into your gas tank, right? Because the car doesn't understand that fuel source. So, what happens is crude oil has to be refined into gasoline, and then the car can run. Okay, so in human beings, there's a similar process called methylation. There's not a single compound known to mankind, not one, there's no vitamin, no mineral, no amino acid, no nutrient, no protein, no nutrient of any kind, that enters the human body and is used in the format that we put it in, without a single exception, everything we put into our bodies has to be refined into the usable form. If you can't make this conversion, you have a deficiency. It's this deficiency that leads to the most common ailments that we suffer from.

Joe Rogan 2:58 Mm.

Gary Brecka 2:58 So, that process is called methylation. And there are several genes that govern it. Um, this is where a lot of the misconception about genetically inherited disease comes from, right? People say, um, "Well, Joe, you know, your father-in-law has ..." Uh, not your father-in-law, your, your father on your mom's side had hypertension. Your grandfather had hypertension. Now you have hypertension. So, you have genetically inherited hypertension, or you have familial hypertension. Well-

Joe Rogan 3:25 And hypertension's commonly known as high blood pressure. Is it the same thing?

Gary Brecka 3:28 High blood pressure. Yeah, high blood pressure. But 85% of all high blood pressure is what we call idiopathic, right? It's of unknown origin. So, we say that things are genetically inherited because they run in families. But it's rarely the disease that's passed from generation to generation. What we pass from generation to generation is the inability to refine a raw material, which causes a deficiency, which leads to that disease.

3:56 – 8:03

Hypertension explained: homocysteine, inflammation, and vascular narrowing

Joe Rogan 3:56 And what generally leads to hypertension?

Gary Brecka 3:58 So, um, if you look at, um, a Dana White s- case, right, is a perfectly, uh, common case. In fact, The Journal of Hypertension published an article in, uh, November 19th of 2017, um, if you wanna look that article up. And essentially linking an amino acid in the bloodstream, um, called homocysteine, uh, to hypertension. And the reason for this is you got homocysteine in your blood, I've got it in my blood, um, everybody listening to this podcast has homocysteine. But if you have an impaired ability to break homocysteine down, right? To take that amino acid, homocysteine, and convert it into a harmless amino acid called methionine, if you can't make this conversion, homocysteine rises. It causes something called hyperhomocysteinemia, high homocysteine in the blood. When homocysteine rises, it becomes one of the more inflammatory compounds in the human body. As it's cruising by the inside lining of the artery, it starts to irritate the artery and actually reduces the artery's, um, elasticity and can even cause it to constrict. So, think about this. You got 63,000 miles of blood vessel roughly in your body. It doesn't take much narrowing to drive pressure up. Think about it, 85% of all hypertensive diagnosis, diagnosis of, of high blood pressure, um, primary hypertension or essential hypertension are idiopathic, right? Unknown origin. Only 15% of them are secondary hypertension of, of where we know the exact cause. And so, what we do is we take people that have high blood pressure. We, we run a bunch of tests on them. We- EKG, it's normal. EEG, it's normal. Heart and lung sounds, cardiac cath, dye contrast study. We do all these cardiovascular tests, and they all come out normal. Yet the person still has high blood pressure. And that's largely because the high levels of homocysteine are causing vascular narrowing. I mean, this is a fixed system, right? So, if I make the pipes smaller in a fixed system, pressure goes up.... so in, in Dana's case, specifically, in his, y- you know, he's thrown in his, uh, blood work out on the internet, so, um, you know, we can talk about his labs. But, um, in his cases, he, he had one of the highest levels of homocysteine that I'd personally ever seen and our clinical team had seen.

Joe Rogan 6:18 What ... So when you say high blood pressure, could you define ... Like g- ... I'm, I'm not good at that. Whenever I get my blood pressure, they tell me the number and they say it's good, and I go, "Okay."

Gary Brecka 6:25 So like-

Joe Rogan 6:26 But I don't know what ... What's a good number?

Gary Brecka 6:27 So, um, 120/70, 120/80.

Joe Rogan 6:30 And what's high?

Gary Brecka 6:31 130, 140, 150, 160.

Joe Rogan 6:34 When does it get dangerous?

Gary Brecka 6:36 140, 150 starts to get dangerous.

Joe Rogan 6:38 Really?

Gary Brecka 6:38 People walk around at 140, 150, 160 all the time.

Joe Rogan 6:43 And they don't know it?

Gary Brecka 6:44 It's the silent killer. You don't feel it. You think you would h- feel high blood pressure, but very often it's the silent killer because you don't feel it. It's not like you hear your blood rushing in your ears, although you may. It's not like you feel pressure in your head, or pressure in your neck, or pressure in your chest. That's why high blood pressure, hypertension is, is one of the silent killers in cardiovascular disease.

Joe Rogan 7:05 Mm.

Gary Brecka 7:06 Right? In fact, one of the, one of the first primary symptoms is sudden death. Right? So we, we often put people on hypertensive medication before we actually look at whether or not they have high levels of homocysteine or whether or not they might have a gene mutation that's specifically called MTR. And you could test for it. Or MTRR. And what this gene codes for is it codes for the enzymes that break down homocysteine and turn it into an amino acid called methionine. Right? And so if this conversion is impaired and this homocysteine starts to rise and your vascular system constricts, it can drive your pressure up. And it drives your pressure up without anything being wrong with the heart. So then we start standing on the heart, which is what happened in Dana's case. Beta blockers, calcium channel blockers, diuretics, all of these things. His blood pressure was still through the roof. Um, and I think-

8:03 – 11:39

Dana’s numbers, medication limits, and the TMG intervention

Joe Rogan 8:03 And what was his number?

Gary Brecka 8:05 I think he was 160, 160/110. I want to say it was very high.

Joe Rogan 8:11 Mm.

Gary Brecka 8:12 Um, and it was consistently high. Um, we were actually ... You know, our clinical team was taking his blood pressure two or three times a day, seven days a week, and it was consistently very elevated, even though he was on blood pressure medication.

Joe Rogan 8:25 Really? So statins. Is that ... What was he ... What was he on?

Gary Brecka 8:29 So statins were just ... What you'd use on, uh, cholesterol.

Joe Rogan 8:32 Oh, okay.

Gary Brecka 8:32 Like, like a Repath or anything. So those are trying to lower-

Joe Rogan 8:34 So what is a, um, what's a hypertension medicine?

Gary Brecka 8:37 They're, they're, uh, they're called beta blockers, like Inderal.

Joe Rogan 8:39 Mm-hmm.

Gary Brecka 8:40 Calcium channel blockers. We call it ACE inhibitors. Um, sometimes we use diuretics.

Joe Rogan 8:45 And so he was still jacked up even though he was on those?

Gary Brecka 8:49 Oh, he was still jacked up even though he was on medication.

Joe Rogan 8:51 And what are the other factors? Like what are ... What other things cause hypertension?

Gary Brecka 8:55 Well, I mean, cardiovascular disease. And there are certain, you know, direct genetic links to cardiovascular disease, but they're, they're very rare. Um, but diet, atherosclerosis, you know, narrowing of the arteries, arterial sclerosis, hardening of the arteries, calcifications in the arterial wall, um, can cause pressure to go up. Um, you know, um, regurgitations in the, in heart valves can cause, you know, pressure to increase. But when you think about the heart as a muscle, right, and all four chambers are circulating blood normally and it's got a good vascular supply, but it's beating into constricted pipes, think about what happens. That pressure's gonna back up.

Joe Rogan 9:34 Mm-hmm.

Gary Brecka 9:34 Right? And so we rarely go outside the heart to diagnose whether or not ... And, and for the record, I am not a physician. I'm not licensed to practice medicine. I'm a human biologist. Um, I didn't, you know, learn my trade in, in, in medical school. I took eight years of undergrad and, and post-graduate education in human biology. But for, for 20 years I was a mortality expert in the insurance industry and I just read medical records for a living. So the vast amount of what I've come to understand about modern medicine has just come from reading thousands and thousands and thousands of medical records. And you can see very often that when people were being diagnosed with high blood pressure, they were always looking at the heart. They never looked outside the heart to say, "Well, could it possibly be beating into a dysfunctional arterial system?" And so in Dana's case, and I, I should have brought the numbers 'cause I had the week over week numbers. It was astounding. You know, we, we just put him on a simple amino acid called trimethylglycine, you know, an amino acid you can get off the shelf. And what it did was it made up for this genetic deficiency, this lack of code to break down homocysteine. And his body started to methylate, to break homocysteine down.

Joe Rogan 10:48 And is this a amino acid that pretty much everybody should be taking?

Gary Brecka 10:51 It's an amino acid that everybody with, um, uh, hypertension should consider if they have high homocysteine.

Joe Rogan 10:58 And s- explain. Say the word again. What is it? What's the amino acid called?

Gary Brecka 11:02 Trimethylglycine. TMG.

Joe Rogan 11:05 Try-

Gary Brecka 11:05 Capital T, capital M, capital G.

Joe Rogan 11:06 Is that the s- Similar to regular glycine?

Gary Brecka 11:08 No. This is trimethylglycine. It's a little bit ... It's a little bit different than the amino acid glycine. So trimethylglycine will actually help to metabolize, to help give the body the raw material it needs-

Joe Rogan 11:20 I feel like I should write that shit down.

Gary Brecka 11:21 ... to ... (laughs)

Joe Rogan 11:22 I'm gonna write down trimethylglycine.

Gary Brecka 11:23 He's gonna be on trimethylglycine tomorrow. (laughs)

Joe Rogan 11:25 Well, I just want, I just wanna keep track-

Gary Brecka 11:28 Yeah.

Joe Rogan 11:28 ... of, uh, all these different things you're saying and oftentimes I do forget. So trimethylglycine.

Gary Brecka 11:32 Yeah.

Joe Rogan 11:32 I'm gonna write that down.

Gary Brecka 11:33 Trimethylglycine. Or just put capital TMG. That's what it'll say on the bottle.

Joe Rogan 11:36 TMG. Okay.

11:39 – 16:30

“Look at the soil”: nutrient deficiency vs disease-first medicine

Gary Brecka 11:39 And so, you know, som- sometimes I use the analogy that, you know, when I was, when I was getting my second human biology degree, I was in grad school getting my human biology degree, I had to take all these plant botany courses, um, which I hated, but you have to take them. Morphology of thalloglaphites and all these crazy courses about plants. But the one thing that really stood out to me by taking all these plant biolo- biology courses is that if there's ever anything wrong in the leaves of a plant, like, the tree, the, um, you know, the trunk, the leaves, uh, or the branches, and you call a true arborist or a true botanist out to your house-... they won't even touch the leaves or the branches or the trunk of the tree. The first thing they'll do is they'll core test the soil. And they'll go, "You know what? This soil's deficient in nitrogen."

Joe Rogan 12:26 Mm.

Gary Brecka 12:27 And then they'll add nitrogen to the soil and the leaf will heal. But we don't think about human beings like this anymore. I feel like there's such a paucity of understanding of, of deep human physiology in, in a lot of the medical community, not all of the medical community. And we don't actually have faith in mankind and humanity and the body's ability to heal itself. And whether or not they might, someone might be deficient in a raw material, not pathologic or diseased. So for example, in Dana White's case, he was diagnosed with idiopathic hypertension, which he essentially did not have. He was being medicated for it, he had been medicated for it for 15 years. And he didn't really have hypertension, there was nothing really wrong with him. It's that his body couldn't break down homocysteine. It was deficient in the amino acids needed to break this homocysteine down. As soon as we put those back in his body, it started to function normally.

Joe Rogan 13:15 And where would you generally get those amino acids if you wouldn't, weren't taking them?

Gary Brecka 13:19 Um, I mean, you can get them online. I mean, there's lots of great manufacturers-

Joe Rogan 13:21 No, no, if you weren't taking them, would, is, is it, are they in food? Is it-

Gary Brecka 13:26 Oh, yeah. They're in, they're, they're in foods. That's why if you look at certain diets, like high folate diets, like carnivore diets, um, diets that are high in dietary folate, leafy greens, um, um, grass-fed meats, um, um, eggs, dairy. You'll find that they have lower incidences of, um, cancer, diets in high dietary folate. So this is a raw material that we can get from our food, but very often our food is just so nutrient deficient, right? We update the macros on the back of a lot of labels, but if you look at the micros, like how much spinach, uh, how much iron is in spinach or calcium is in spinach or how much, um, nutrients are in the, on the label of most foods, I mean, it's a fraction of what's actually listed there.

Joe Rogan 14:10 Mm.

Gary Brecka 14:10 And so we're nutrient deficient, right? Human beings are not as sick as we have been led to believe we are. The majority, in my opinion, of pathology and disease as we know it today are nutrient deficiencies, missing raw material in the human body. And we just accept all these things as a consequence of aging, weight gain, water retention, you know, lack of sleep, poor focus and concentration, lack of waking energy, hormone imbalance. And we think that the body has all of these different pathologies and diseases, but the truth is, it's usually nutrient deficient. It's astounding what happens to human beings when you give their body the raw material that it needs to do its job.

Joe Rogan 14:49 Mm.

Gary Brecka 14:49 I mean, it really is. And so if, if you are just supplementing for the sake of supplementing, then there's only a marginal chance that you're getting what you need. If you're supplementing for deficiency, that's when magic happens in the human body.

Joe Rogan 15:04 But you have to understand what those deficiencies are and you have to go to someone like yourself that's gonna-

Gary Brecka 15:09 You don't have to come to me. I mean, there's lots of people that do genetic tests, but-

Joe Rogan 15:12 But someone like yourself-

Gary Brecka 15:12 Yeah.

Joe Rogan 15:12 ... that is gonna understand how to read this stuff. 'Cause if you ha- uh, if you talked to me and said, "Uh, what's the cause of high blood pressure?" I would probably say, "Someone's fat. They're overweight, they eat too much, maybe they drink too much."

Gary Brecka 15:26 Yeah, those are very obvious causes.

Joe Rogan 15:27 Or-

Gary Brecka 15:27 Type 2 diabetes.

Joe Rogan 15:28 Right.

Gary Brecka 15:29 Um, you know, being morbidly obese, atherosclerosis, arteriosclerosis.

Joe Rogan 15:32 What are the other factors that could be?

Gary Brecka 15:35 Um, obesity. Um-

Joe Rogan 15:37 Yeah, we talked about that.

Gary Brecka 15:38 Yeah, obesity, stress, um, sleep dep-

Joe Rogan 15:40 Stress?

Gary Brecka 15:41 Oh, stress and sleep deprivation.

Joe Rogan 15:43 Hm.

Gary Brecka 15:43 High levels of cortisol. Um-

Joe Rogan 15:44 Interesting.

Gary Brecka 15:45 Um, so slep- uh, sleep deprivation, stress, um, morbid obesity, type 2 diabetes, atherosclerosis, arteriosclerosis. But those are usually more sinister and visible. You know, there are a lot of healthy looking individuals in their 20s and early 30s that are walking around with hypertension, with high blood pressure and don't know it. There are a lot of young, healthy looking individuals that are walking around with metabolic syndrome, which is a combination of very high blood fat, triglycerides, abdominal fat, um, high blood pressure, high insulin, and high sugar. But they don't, they don't manifest to the outside world, but it's going on on the inside.

Joe Rogan 16:30 Hm.

16:30 – 26:35

MTHFR, folic acid fortification, and behavioral/mood effects

Gary Brecka 16:30 That, that's why I say I think everybody at, once in their lifetime should do a genetic methylation test. And the reason for that is that you do this test once in your lifetime. You never have to repeat it. The genes you're born with are the genes you die with. And based on, there's five major genes of methylation. Based on how these five genes are working or not, you supplement for their deficiency. So for example, one of the most common gene mutations in the world is called MTHFR. It's called the motherfucker gene. (laughs)

Joe Rogan 17:00 Hm.

Gary Brecka 17:00 Um, stands for methylene tetrahydrofolate reductase, but we call it the motherfucker gene. This gene is estimated to be compromised in somewhere between 40% and 60%, depending on the study. 40% to 60% of the population has this gene mutation. And what this gene mutation does is it interrupts the ability to convert folic acid into the usable form called methyfolate. And while that might not sound like a big deal until you realize that folic acid is the most prevalent nutrient in the human diet. Folic acid, by the way, is an entirely man-made chemical. You can't find folic... We've been, we've been lied to about folic acid. I mean, it's, it's entirely man-made and synthetic. You can't find folic acid anywhere on the surface of the Earth. It does not occur naturally in nature. Folate does, but we make folic acid in a lab. And then what we've done since 1993 is we've sprayed all of our grains, all white flour, all white rice, all white bread and grains of any kind are sprayed with this chemical folic acid. It's called fortified or enriched. So when you, when you spin a box of crackers around and it says fortified whole wheat flour or enriched bleached white flour, that means it's been sprayed with folic acid. Well, 44% of the population can't convert that into the usable nutrient.

Joe Rogan 18:18 Why do they spray it with folic acid?

Gary Brecka 18:20 Well, I mean, without going down the whole road of conspiracy theory, I mean, you look at the same, you know-... pharmaceutical companies that produce folic acid, and you look at some of the, um, you look at some of the downsides of having a synthetic form of a vitamin like folic acid in the diet, and how it's correlated to higher incidences of ADD, ADHD, OCD, manic depression, bipolar. Um, it's correlated to poor gut motility, mood imbalance, anxiety. And because when you put this raw material into the human body, if you can't metabolize it, if you can't methylate it into the usable form, first of all, you now have a deficiency in the form your body needs and an excess in the nutrient you can't process. And this causes things to go haywire.

Joe Rogan 19:10 So instead of folate, it's folic ac- folic acid. And what does your body try to do with that?

Gary Brecka 19:16 So your body tries to convert folic acid into, eventually into something called methylfolate.

Joe Rogan 19:23 Right.

Gary Brecka 19:23 There's a few steps in between, tetrahydrofolate, dihydrofolate, but essentially folic acid and folate, which c- you can find all over the surface of the earth, gets converted into the usable form called methylfolate. Okay, now, this is one of the most, uh, common util- commonly utilized methylated nutrients in the human body. It helps down regulate neurotransmitters. It helps improve the intestinal motility of our gut. Um, it helps degrade thought. It helps b- actually break down catecholamines, which are fight or flight neurotransmitters that can actually stimulate thought. And so people will go a lifetime eating white bread, white flour, white rice, white pasta, uh, you know, um, breads and cereals of all kinds, and they're reading the label and they're like, "Wow, it's fortified, it's enriched."

Joe Rogan 20:13 Hm.

Gary Brecka 20:13 But fortified or enriched for 44% of the population means you can't break that, that nutrient down. This is why there, there, there's a lot of evidence that getting folic acid out of the diet has immediate behavioral changes. I mean, if you're a parent and you're listening to this podcast and it's a full contact sport to get your kid in the car to go to school in the morning, look at what you're feeding them. The standard American diet is gonna be like a Pop-Tart, a white bagel, a bowl of cereal, right? And all of those are fortified with folic acid. Well, there's a 44% chance your kid can't process that, and you're amping them up in the morning.

Joe Rogan 20:49 Hm.

Gary Brecka 20:49 It can literally be like cocaine for a six-year-old, right? It could make their mind race. So now this kid gets up and he goes to the breakfast table and he has a Pop-Tart or he has a white bagel or he has a bowl of cereal, he dumps all this folic acid in the body, and now his mind starts to ricochet, right? And, and it's a full contact sport to get him in the car. And then by the time they get to school, this, you know, the call is coming home saying, "Hey, little Johnny can't pay attention. He doesn't focus, he can't concentrate, he doesn't follow directions, can't pay attention."

Joe Rogan 21:15 Get him on Adderall.

Gary Brecka 21:16 Yeah. Get him on Adderall or Ritalin.

Joe Rogan 21:17 Hm.

Gary Brecka 21:17 And you know, essentially what that does is it says, all right, well if the mind is racing, um, then let's put an amphetamine into the body to race the central nervous system to match the pace of the mind.

Joe Rogan 21:30 Dude.

Gary Brecka 21:30 Which is a horrible solution. How about we just quiet the mind, right? Because you know, it, it... In our brains, we, we don't just create thought, right? We also dismantle thought. We break thought down, right? We transfer methyl groups from neurotransmitters and break them down so they no longer have an effect, right? Or else you'd always be in the same mood. So when we start creating thought at a faster rate than we break thought down, we call this ADD or ADHD, right? But it's not an attention deficit at all. In, uh, in many of these cases, it's an attention overload disorder. It's too many windows open at the same time, right? So if we're opening too many windows, now all of a sudden we can't pay attention. So, uh, it is not that the majority of people with ADD or ADHD lack the ability to pay attention, because they actually can hyperfocus. They lack the appen- uh, ability to pay attention to so many things, right? So, you know, you're thinking about a job you're working on and your friend walks up and you're thinking about a job, and you start talking to your friend and you notice a logo on your friend's jacket that reminds you of a vacation you want to take. So now you're thinking about a job, talking to your friend, looking at the logo, thinking about a vacation you want to take all at the same time. And why is this? Because very often it's because you have slow breakdown, slow methylation of neurotransmitters. So thought, thought, thought comes in, and now all of a sudden we're like, "This kid can't pay attention. This guy's all over the place."

Joe Rogan 23:00 Huh.

Gary Brecka 23:01 If you look at the link between that simple gene mutation, MTHFR, and its incidents in, um, its incidents in, uh, stroke, cardiovascular disease, its incidents in, um, ADD and ADHD and OCD, you'll find not a direct causal link, but enough of a prevalence to say, "Why wouldn't we just take folic acid out of the diet, add methylfolate and take a shot at correcting the course of these conditions?"

Joe Rogan 23:34 So folic acid, when did it get introduced into the human diet?

Gary Brecka 23:40 1993 is, I think, when the federal government signed a deal to spray our entire grain supply with folic acid. I want to say it was 1992 or 1993. And I forget if it was Monsanto, I forget the pharmaceutical company that convinced the US government to, um, spray our entire grain supply. But before that date, like you ever notice when you go to Europe and you eat bread in Europe, you don't feel like shit?

Joe Rogan 24:02 Yeah.

Gary Brecka 24:02 Or you go to, you go to Italy and you have a bowl of pasta and you're like, "Man, normally when I eat pasta, I feel like shit. It just sucks."

Joe Rogan 24:07 Yeah.

Gary Brecka 24:07 Okay, that's because it's not sprayed with folic acid.

Joe Rogan 24:11 Really?

Gary Brecka 24:11 Right.

Joe Rogan 24:11 Because I'd always been told that it's heirloom grains and that our n- uh, the wheat that we have today has been modified, uh, for higher yield, for smaller acreage-

Gary Brecka 24:21 Not in the US.

Joe Rogan 24:21 ... and is more complex

Gary Brecka 24:22 Well, genetically modified, first of all, you know, the GMO foods. So, um, you know, Italy banned GMO foods. Russia, actually, it's a felony to grow genetically modified foods. Um, so-... GMOs aside, and that's another thing. I mean, I tell people, "You gotta get GMO foods out of your diet." Right? We didn't genetically modify s- uh, seeds to increase yield. We modified g- seeds to be resistant to glyphosate, right? The poison in pesticides. But if you go back to the folic acid, and seed oils for that matter, but if you go back to the folic acid theory, if we stopped spraying our grains, just, just for 30 days. Don't even stop eating white bread, white flour, white pasta, white rice, um, or grains, if that's what you eat. Um, I don't eat any of those things. But if, but if that's what you eat, don't stop eating them. Just switch to the organic, non-fortified, non-enriched version, and watch what happens to your mood, your focus, your concentration, your short term recall, the depth of your sleep and your waking mind at night.

Joe Rogan 25:25 But the vast majority of wheat and rice and things that you do buy will have been enriched with folic acid.

Gary Brecka 25:31 All of it in the United States-

Joe Rogan 25:32 All of it.

Gary Brecka 25:33 ... unless it's organic.

Joe Rogan 25:35 Wow. So if someone's buying a sandwich, and you're getting it on regular bread, you're just getting a heap of folic acid.

Gary Brecka 25:42 Getting a heap of folic acid.

Joe Rogan 25:43 Get a bowl of pasta, you're getting a heap of folic acid.

Gary Brecka 25:45 Mm-hmm.

Joe Rogan 25:46 And-

Gary Brecka 25:46 A bowl of rice that's not organic, heap of folic acid.

Joe Rogan 25:48 And your body's like, "What the fuck is this?"

Gary Brecka 25:50 Your body's like, "What the fuck?" Just, just be a t- pay attention to your mood after you eat high amounts of some of those things.

Joe Rogan 25:57 Oh, believe me, I'm very aware.

Gary Brecka 25:59 (laughs)

Joe Rogan 25:59 (laughs) It's my, my number one weakness.

Gary Brecka 26:02 Yeah.

Joe Rogan 26:03 My number one weakness is bread and pasta.

Gary Brecka 26:05 S-

Joe Rogan 26:05 Like if I do go off the rails with a diet, like I have a cheat day, that's what I cheat with.

Gary Brecka 26:10 Okay. So try, try next time you go off the rails eating non-fortified, non-enriched pasta, rice, bread, fl-

Joe Rogan 26:17 Well, I have absolutely noticed that when I've gone to Italy.

Gary Brecka 26:21 Yeah.

Joe Rogan 26:21 100% noticed it.

Gary Brecka 26:22 That's why.

Joe Rogan 26:23 Eating pasta, it just seems normal. It do- Like, you know, I hear a lot about a lot of people that have gluten allergies and gluten intolerances, and now I'm wondering, like, "What does that mean?"

Gary Brecka 26:32 Well, the foods that contain gluten very often are the foods that contain folic acid.

Joe Rogan 26:35 Right.

26:35 – 29:02

Prenatal vitamins, methylfolate vs folic acid, and postpartum depression claims

Gary Brecka 26:35 Remember, 44%. This happens to pregnant women too, right? You know, postpartum depression, which, for the record, can begin before the pregnancy is over. Sometimes I get slaughtered online for saying, "Oh, you're talking about postpartum depression before the pregnancy ends." Yes, the diagnosis of postpartum depression happens very often before the pregnancy, before the pregnancy is carried to term. So 44% of women have this gene mutation. What's the first thing their OB-GYN tells them to do when they get pregnant? Take high doses of folic acid. Well, 44% of them can't process this folic acid. So what happens?

Joe Rogan 27:07 Why do they tell them to take high doses of folic acid? What's the logic behind it?

Gary Brecka 27:10 Because they're told that folic acid prevents neural tube defects, which is patently false.

Joe Rogan 27:14 Hm.

Gary Brecka 27:14 Folic acid doesn't prevent anything.

Joe Rogan 27:16 And are they-

Gary Brecka 27:17 Methylfolate prevents neural tube defects.

Joe Rogan 27:18 Are they told to take it in supplemental form? Are they told to take it in form of foods that are sprayed with folic acid?

Gary Brecka 27:24 They're told to take it in supplemental form. If you look at the majority of cheap prenatal vitamins, right? The good ones, like Thorne, Pure Encapsulations, some of these b- you know, really good big brands, they will have methylated versions of vitamins, right?

Joe Rogan 27:38 Okay.

Gary Brecka 27:38 They'll take the folic acid out.

Joe Rogan 27:39 Right.

Gary Brecka 27:40 Because what happens if you're pregnant, you have this gene mutation, MTHFR, um, number one, you have a skyrocketing incidence of miscarriage. But then because you don't have the methylfolate that your body needs for the adhesion of the egg into- implant into the uterine wall. But now she's pregnant and she starts to take a prenatal vitamin with 1400, 1600% of the daily allowance of folic acid. She starts to go nuts, right? Develops postpartum depression. Eventually, the pregnancy ends, she stops taking the prenatal vitamin, and the symptoms go away. But she still blames it on the pregnancy, not on the vitamin.

Joe Rogan 28:16 Whoa.

Gary Brecka 28:16 The truth is, I have yet to see a peer-reviewed published clinical study linking pregnancy hormones to, to postpartum depression.

Joe Rogan 28:24 Now, is there a benefit to taking methylfolate as supplement form?

Gary Brecka 28:27 A huge benefit to taking methylfolate.

Joe Rogan 28:29 And what, uh, how do you get methylfolate? Is it-

Gary Brecka 28:31 So you, you, you buy methylfolate. You get the methylated form of that nutrient. This is why I say if you, if you look at five particular genes, MTHFR, MTRR, MTR, AHCY, and COMT, dude, if you find that you have one of those gene mutations and you supplement for their deficiency, magic things will happen in your body. You know, because if you have that, for example, there's a gene mutation called

29:02 – 32:55

Anxiety, COMT, racing thoughts, and sleep: physiology-first framing

Gary Brecka 29:02 COMT, catechol-O-methyltransferase, and, you know, we all know people that are suffering from anxiety. If, if, if we haven't suffered from anxiety ourselves, chances are we know somebody who's suffered from anxiety. And if you really break down what anxiety is, right? A fear of the future, um, you know, we have to understand that it doesn't require the presence of a fear for us to feel fear, right? So you could drive home tonight and pull into your driveway, and when you get outta your car, somebody's standing in front of you with a knife, right? So that's a real fear, right? Your pupils are gonna dilate. Your heart rate's gonna increase. Your extremities are gonna flood with blood. You're gonna start to have a fight or flight response, mainly because an area of your brain has dumped catecholamines, fight or flight neurotransmitters, into your brain. Boom, now you start to have a fight or flight response. But you could also be laying on the 30th floor of a condo in bed and you could just start thinking about getting eaten by a shark.

Joe Rogan 29:57 Yeah.

Gary Brecka 29:57 Okay? And the chances of a shark getting out of the ocean and coming up a 30-floor elevator, right, are zero. But you can have the exact same reaction. So how is it that I can have the same reaction to the presence of a real fear as an entirely perceived fear? Because it doesn't require the presence of a fear for these excess catecholamines to leak into the brain.

Joe Rogan 30:19 Huh.

Gary Brecka 30:19 And this is the- why the majority of anxiety that we have seen in our practices, um, that my clinical team treats, is coming from our physiology. It's not coming from our outside environment. In fact, if you ask most people that suffer from anxiety three questions, if you say, "Have you had it on and off your entire lifetime?"... they'll say yes. There's your first sign that it's a genetic deficiency. Um, and then you say, "Well, can you point to the specific trigger that causes it?" They'll say, "Most of the time, I can't." There's your second sign that it's not coming from their outside environment. And then the third question is, "If you've ever tried anti-anxiety medications, have they worked?" The majority of the time, they'll say, "No, it just makes me feel like a zombie." That is very indicative that this is a nutrient deficiency and not a mental condition. We have a lack of-

Joe Rogan 31:06 Whoa.

Gary Brecka 31:06 Yeah.

Joe Rogan 31:07 So, do you encourage people to take methylfolate as a supplement or do you-

Gary Brecka 31:11 Absolutely. I encourage them-

Joe Rogan 31:13 What's the dose that they should take?

Gary Brecka 31:15 ... I think everybody shou- Um, well, it's, it's weight dependent but, you know, um, methylfolate, about 800 micrograms, um, a day is usually defi- is usually sufficient unless-

Joe Rogan 31:23 Is that something you take with food?

Gary Brecka 31:25 Um, you can take it with or without food. It's a, it's a non-water... it's a water-soluble vitamin, so unlike vitamins A, D, E and K, which are actually fat soluble that you need to take with food for them to be absorbed, you can actually take those even on an empty stomach, as long as you're not taking them with a bunch of other vitamins that cause you to be nauseous 'cause it changes your stomach pH. I think every single person should be at a minimum on a methylated multivitamin.

Joe Rogan 31:48 Mm.

Gary Brecka 31:49 The basic raw materials that your body needs to perform the process of methylation, because methylation is how we create neurotransmitters, right? I mean, we make serotonin from taking tryptophan and amino acid and methylating it into-

Joe Rogan 32:02 Right.

Gary Brecka 32:02 ... serotonin. We make, we make dopamine from, um, you know, phenylalanine and tyrosine. If, if you can't make these conversions, you have certain deficiencies. And yes, you can have deficiencies in neurotransmitters, which will lead to the expression of a mood disorder. You don't have a mental illness, you just have a lack of mental fitness. And this is- this is why I think-

Joe Rogan 32:23 That's crazy.

Gary Brecka 32:24 ... that we- we- we're so quick to say that we have pathology and disease or dysfunction, and then we go to chemicals and synthetics and pharmaceuticals. And I'm not anti-pharmaceutical, but what I'm saying is, before we diagnose somebody with a mental illness or an autoimmune disorder, or with an allergy or a sensitivity, or irritable bowel syndrome, or any number of other conditions, we should ask ourself what raw material could be missing from their body that could be causing this to happen.

32:55 – 39:08

Medication overreach examples: vitamin D deficiency misread as autoimmune disease

Gary Brecka 32:55 Right? I mean, like, when I was in the- when I was in the mortality space, you know, for- for- for 20 years, you know, I was reading medical records, just horrific voluminous amounts of medical records. I would see simple nutrient deficiencies get misdiagnosed as autoimmune conditions more times than I can even remember. So for example, you know, you'd have people going to their primary care physician and I would look at their medical records for five, eight, 10 years. Sometimes we had more than 10 years of medical records, and I'd see, man, this person has single digit vitamin D3 levels. Like, they are so clinically deficient in, in vitamin D3, and vitamin D3, you know, goes from about 30 nanograms per deciliter to 100 nanograms per deciliter. 60 to 80 is a perfect range, but chronic deficiency in vitamin D3, the sunshine vitamin-

Joe Rogan 33:40 Mm-hmm.

Gary Brecka 33:40 ... right, the only vitamin, by the way, that human beings can make on our own. I- I think it's arguably the most important nutrient in the human body. In fact, it was the second leading cause of morbidity in COVID for people that had a deficiency. And it's also why we said that COVID disproportionately affected minorities, because there's a higher incidence of vitamin D3 deficiency because of the pigment of their skin. But we would see- we would see these deficiencies in vitamin D3 that had gone on for decades, right? Now, all of a sudden the patient is going into their doctor and saying, "Doc, I wake up sore and achy in the morning like I had a workout the night before when I haven't. The soles of my feet and my ankles are sore when I get out of bed in the morning to walk to the bathroom. My knees and hips really bother me lately. And you know what? Just these past few weeks, it's kind of hard to make a fist." You would be shocked how many family medicine practitioners go, "You know what, Joe? You got, uh, rheumatoid arthritis. I'm gonna hit you with some high-dose prednisone. I'm gonna put you on something called a corticosteroid and you're gonna be fine." Well, we knew in the mortality space that if you ta- started corticosteroids, you had six years and one day until you were having a joint replacement. It was so accurate that if I saw you were misdiagnosed with rheumatoid arthritis and started a corticosteroid, I would artificially advance your age six years and one day, and I would schedule the joint replacement. And then what I would do is I would model the reduction in what we called your ambulatory profile, how well you ambulate, how well you move. Because sitting is the new smoking, right? Sedentary lifestyle is the leading cause of all-cause mortality. And so as I reduced your mobility, I would bring in all the diseases that exacerbate with reduced mobility. So now if you rewind that, you had a simple nutrient deficiency in vitamin D3, cholecalciferol. You were diagnosed with a condition you did not have, put on a medication that wasn't required, which led to a joint replacement that wasn't nece- necessary.

Joe Rogan 35:30 How does- how do these corticosteroids, how do they r- ruin your joints? How does that happen?

Gary Brecka 35:36 So eventually what they do is they upset the balance inside the joint, the synovial, um, the, the protein balance inside of the synovium of the joint. So initially they act- (clears throat) initially they act as an anti-inflammatory, right? They- they reduce the inflammation and you- you actually feel a little bit better. Um, it's like cortisone. You know, repeated cortisone injections have ended a lot of professional athletic careers, probably Joe Montana being the biggest, but, um, that's why we try to reduce the amount of cortisone that we actually put into, you know, athletic injuries now. But- but-

Joe Rogan 36:09 H- but h- what is the mechanism? Like how does it do that?

Gary Brecka 36:12 It- it becomes cytotoxic to the joint because it interrupts the protein metabolism in the synovium of the joint. And so what happens is the joint begins to dry out and the friction surfaces become less lubricated and then begin to contact one another. And as they contact one another, because this protein is broken down, we wear the friction surface away and you get down to anchor cartilage, which we call bone on bone, and there's a lot of nerves there, and you start to get a lot of- of joint pain.So, corticosteroids will also, um, like methotrexate, they also block and interrupt the ability for the body to convert folate to methylfolate.

Joe Rogan 36:51 Mm.

Gary Brecka 36:52 They artificially give you the same condition as this gene mutation, which is why one of the biggest side effects of corticosteroids is gut issues, because methylfolate is r- involved in the motility of the gut. You now start taking a corticosteroid, and it shuts your gut down.

Joe Rogan 37:09 And by corticosteroids, are you talking about prednisone? Like, what are the ones that they prescribe?

Gary Brecka 37:12 Prednisone, methylprednisone, um, and other oral corticosteroids ............................

Joe Rogan 37:17 'Cause I, I have a friend who had gout, and they put him on prednisone.

Gary Brecka 37:21 For short periods of time, you know, in the acute inflammatory stage, it's okay. But to take prednisone systemically, um, for a prolonged period of time, you're gonna start to hear that he starts to get low back pain, that he... Well, first of all, I'd be very surprised if he doesn't have gut issues right now. If you ask him, "Hey, do you, do you notice the incident of gas, bloating, diarrhea, constipation, irritability-"

Joe Rogan 37:43 Hmm.

Gary Brecka 37:43 "... cramping kind of going up when you started those corticosteroids?" He'll go, "Yeah, dude, my gut's a freaking mess."

Joe Rogan 37:49 Mm.

Gary Brecka 37:50 "You know, I'm constipated sometimes, and I get, then I get diarrhea. Sometimes I blow up like a tick."

Joe Rogan 37:55 So, to take it back to cortisone, so if someone has an injury, should, would you advise them to never take cortisone? Is it occasionally okay?

Gary Brecka 38:03 Occasionally, it's okay. I think most orthopedics now are trying to get away from repeated injections of cortisone other than at the inception of the acute injury.

Joe Rogan 38:13 'Cause I know a lot of athletes, you know, they'll get a, a cortisone shot if they have to perform.

Gary Brecka 38:18 Yeah, I mean, if they have to perform, but remember, that, that's also gonna cause, you know, ligamentous and tendonous laxity. You know, it's actually can be cytotoxic to those, um, to those tissues. It's cytotoxic to fibroblasts, which are the little cells that are embedded in, in, in those tissues that actually help promote healing, right? Because, um, there are, there are cells in injured tissues that are essentially, through the inflammatory process, calling platelets to the site of an injury, right?

Joe Rogan 38:46 Mm-hmm.

Gary Brecka 38:46 Which is one of the ways that we heal. We call platelets to the site of the injury. The platelet itself is kind of useless, but it has growth factors inside of it. When it arrives on site, it bursts, it drops off the growth factors, and now you start this, this healing process, which is one of the reasons why PRP works so well. You know, platelet-rich plasma, 'cause you're ta- you're, you're taking all the platelets from the body, and you're concentrating them into a site of injury, right?

Joe Rogan 39:08 Hmm.

39:08 – 1:01:03

Peptides, BPC-157 controversy, and FDA/censorship frustrations

Gary Brecka 39:08 It's why, um, man, I used to love BPC-157 till the FDA (laughs) just came down on it.

Joe Rogan 39:14 What the fuck is that about?

Gary Brecka 39:15 Ah, fuck, dude. It just-

Joe Rogan 39:16 Why did they do that?

Gary Brecka 39:17 You know what's, what's astounding is I read that whole report, and it wasn't for safety reasons, right? It wasn't, it wasn't because of the reporting of massive amounts of, um, anaphylactic shock or hospitalizations-

Joe Rogan 39:30 Right.

Gary Brecka 39:30 ... or overuse or, um, um, you know, or, or, you know, somebody having some kind of illness or effect or, you know, shock because of it. It was because of the lack of safety data, which is another way of saying it hasn't been paid to be put through full-blown, you know, FDA clinical trials, which no one's gonna do, and, and-

Joe Rogan 39:50 So, does that make BPC-157 impossible to get now?

Gary Brecka 39:54 It will, yeah, and, and a whole host of other-

Joe Rogan 39:58 But it's so effective.

Gary Brecka 39:59 It's so effective. I mean, I can't even begin to tell you how many thousands and thousands and thousands of patients my clinical team has put on BPC-157 never with an adverse event. It is so good for the gut. It's a gastric pentapeptide. It's, it's, um, you know, it's actually synthesized from gastric juice, so it, it's actually tolerated very well orally.

Joe Rogan 40:19 I started to see it orally-

Gary Brecka 40:20 Yeah.

Joe Rogan 40:20 ... which I never really saw before. I always saw it as an injectable, but I see it advertised as orally.

Gary Brecka 40:25 Well, site injecting it into the site of an injury, like if you have a lateral epicondylitis or something, you inject it to that site of injury is very good, right? It'll localize there and kind of help call platelets to that location. But it's also extraordinarily good for leaky gut.

Joe Rogan 40:40 Hmm.

Gary Brecka 40:41 Um, so people that suffer from inflammatory conditions of the bowel, irritable bowel syndrome, Crohn's disease, diverticulitis, uh, those, those sorts of things, you know, um, BPC-157 can be just a game changer.

Joe Rogan 40:53 Hmm.

Gary Brecka 40:54 'Cause it is tolerated well, orally.

Joe Rogan 40:55 And they're gonna get rid of it?

Gary Brecka 40:56 They're gonna get rid of it.

Joe Rogan 40:57 Look at these motherfuckers.

Gary Brecka 40:58 (laughs) I know.

Joe Rogan 40:59 These motherfuckers.

Gary Brecka 41:00 It's fucked up. You know, they're amino acids. They're amino acid sequences. I mean, same with growth hormone peptides, you know? Well, sermorelin's still being allowed, but ipamorelin, CGC 1295, MK-677, ibutamoren. These growth hormone peptides that kept people off of exogenous growth hormone, that worked with the naturopathic circadian release of growth hormone, that helped lots of older people fight sarcopenia, age-related muscle wasting, with virtually no side effects. By the way, so, you know, sermorelin, I think was first FDA approved in 1983, if I remember correctly. So, you know, these things have been around for decades. We have lots of safety data o- on, on these and thousands and thousands of patients without an adverse event, and we're gonna have to, we're gonna have to drop it.

Joe Rogan 41:47 And so do you think they're doing this because they want the drugs to go through these safety protocols, or do you think they're doing it because they see that people taking peptides limit the amount of pharmaceutical drugs they take?

Gary Brecka 42:02 Well, I think, I think it's a little bit of both, right? I mean, uh, the question is, where is the impetus coming from? Is it coming from the impetus to protect the public? Because if you're trying to protect the public, then why would you look at the-

Joe Rogan 42:12 Get rid of opiates.

Gary Brecka 42:13 Yeah, I mean, okay.

Joe Rogan 42:14 How come those are still available? Yeah.

Gary Brecka 42:16 Yeah, look at the addictive amyloids and opiates, and look at the side effects of... I mean, we, the whole serotonin hypothesis in depression has been disproven, but we still put people on SSRIs for depression. You know, serotonin reuptake inhibitors, and people are on these things for 15 or 18 years.

Joe Rogan 42:28 Yeah.

Gary Brecka 42:28 Right? Which is another, by the way, thing that methylation helps to fix. Um, it's, it's, it's not that all depression is related to methylation, but the, the prevailing theory when I was in the mortality space was that if you were low on serotonin, you were by definition depressed. And I was like, well, if the serotonin hypothesis were true, I was thinking about this back then, and now it's been disproven, then if, if low serotonin were depression, then why wouldn't we just raise serotonin?... why would we put people on a selective serotonin reuptake inhibitor that just rations or slows the uptake of serotonin rather than increase the supply of serotonin?

Narrator 43:05 Like with 5-HTP?

Gary Brecka 43:07 Like with 5-HTP, with, like, turning methylation back on-

Narrator 43:10 Mm-hmm.

Gary Brecka 43:10 ... from both 5-methylfolate, with the complex of B vitamins. Um, reducing... You know, urinary catecholamines are associated with anxiety and depression, and you can re- you can reduce urinary catecholamines with simple supplementation, B complex of methylated vitamins, um, you know, uh, methylated folate, sometimes something called SAMe, S-adenosylmethionine. These are generally harmless amino acids and methylated vitamins that people just need so their body can perform its duty-

Narrator 43:41 Mm-hmm.

Gary Brecka 43:41 ... so it can perform its job. You know, like, I- I- I work with- with people all the time that come in and they're like, um, "Man, my gut is a mess, Gary. You know, I've had irritable bowel syndrome or I've had, you know, Crohn's disease or diverticulitis or I have intermittent gas and bloating and constipation and irritability and cramping." And, um, you know, and I- I- I'll get their allergy test and they're like, "Man, I'm allergic to all these things, wheat, soy, corn, dairy, blueberries, bananas." I'm like, "Okay, let's- let's slow this down. Um, let's just take corn, for example. You say you're allergic to corn. Is there ever a time that you can eat corn and not have a reaction?" And they go, "Yeah, sometimes I can eat corn and not have a reaction." "Okay, then you're not allergic to corn because allergies are not transient. Allergies are consistent. So if you can sometimes eat it and sometimes not, you're not allergic to it. You don't have a sensitivity or an allergy; you have a gut motility issue." It's the most overlooked thing in all of bariatric medicine, in my opinion, because we- we stop thinking of the gut as a conveyor belt, right? It's like, remember Henry Ford? He was- he wasn't made famous for the automobile. He was made famous for the- for the-

Narrator 44:46 Production.

Gary Brecka 44:46 Yeah, for the assembly line.

Narrator 44:47 Yeah.

Gary Brecka 44:48 Right? So- so the assembly line was just a glorified conveyor belt. You put a part on it at one end, and as it kind of traverses the- the assembly line, you know, every few feet, somebody just tinkers with the part, tinkers with the part. And by the time it reaches the end, it's fully assembled. W- well, the human intestinal tract is no different, right? It's just a glorified conveyor belt. It's 30 feet long. We put contents on it at one end as it exits the stomach in a very acidic environment, and as it traverses the gut, it generally becomes slightly more alkaline, then it exits the rectum. That sequence of events is very important, right? If Henry Ford just walked into his factory one day and doubled the speed of the conveyor belt, what would happen? The entire line would break down. Nothing wrong with the conveyor belt, nothing wrong with the part on the conveyor belt, nothing wrong with the people working there, nothing wrong with the food, nothing wrong with the bacterial flora. It's not a- it's not gust- gut dysbiosis, it's not, um, improper flora, it's not an allergy, it's not a sensitivity. It is a gut motility issue. When you change the motility of the gut, you get all of the outcomes that look like, um, uh, food sensitivity, food allergy, um, you know, uh, m- bacterial flora being off, and then people start shoveling down probiotics and they get all this allergy testing and they go on these restrictive diets, and it doesn't seem to help, because they haven't addressed the motility issue. Methylfolate, complex of B vitamins, um, very often will give your body the- the raw material it needs to restore that peristaltic activity, and then you can get off the proton pump inhibitors and the Tums beca- for the acid reflux, which is now, you know, screwing things up down the- down the line. So, you know, again, I always come back to this theory that we should always look at the soil before we diagnose the disease or the pathology, because there's very little to lose by saying, "What nutrient deficiency could this person have that could be causing this condition to exist?" It's like when people come into our clinics for hormone therapy. You know, very often, we don't put them on hormone therapy. We just put them on nutrients to support healthy hormone therapy, right? I mean, if you have low vitamin D3, low DHEA, and high protein in your blood called SHBG, your hormones are going to be off, right? Free testosterone's going to be clinically deficient. Testosterone will probably also be low. And you don't need hormone therapy. Your endocrine system hasn't failed you. Your body just doesn't have the raw material it needs to do its job to produce those hormones.

Narrator 47:14 Mm-hmm.

Gary Brecka 47:14 So, you know, I- I- I really wish we would stop- or we would start going back to studying human physiology and saying, "What could we put back in this body so it can perform optimally?" I really think magic things happen to human beings if their body just has the raw material it needs to do its job.

Narrator 47:34 And most people don't.

Gary Brecka 47:35 And most people don't. But they don't-

Narrator 47:37 And the vast majority of people are nutrient deficient.

Gary Brecka 47:39 They're nutrient deficient, but they don't know what nutrient they're deficient in.

Narrator 47:42 Right.

Gary Brecka 47:42 They don't know what these five genes tell them, and they don't know whether or not they should be supplementing with methylfolate, um, avoiding folic acid, whether or not their sleep is related to their gene mutation. So, for example, if you have the gene mutation COMT, you have one of two types of sleep patterns. You- you lay down tired to go to sleep, so your body tired, but your mind is awake. And so what happens is your environment quiets, your mind wakes up. And these people, if you- if you ask them, "Well, what are you thinking about at night?" They'll tell you it's the most innocuous little nonsense. It's like, "Did I get everything on my grocery list today?"

Narrator 48:19 Right.

Gary Brecka 48:20 "Did- did my belt match my shoes? You know, did I return that Instagram po-" It's nothing that couldn't wait till the next day. Right? So why does the mind wake up at night? Because we are- we are releasing these catecholamines into the brain. We're not breaking them down at the right rate, so our mind is awake. Catechol-O-methyltransferase, this COMT, takes those- those excitatory neurotransmitters and it breaks them down. This is why things like magnesium and zinc and SAMe, um, uh, you know, work so well to help people sleep. They're not actually sleep aids. They're methylation aids.... that help you break down-

Joe Rogan 48:58 Mm.

Gary Brecka 48:59 ... neurotransmitters that create that awakened state. And this is why, um, you know, those some, same people will, will say, "You know, I work really well under pressure," right? Well, physiologically, when you tell me you work well under pressure it says, you, you're saying to me, "Well, um, I lack the ability to set priorities internally. So I use external pressure to set my priorities for me." Well, what if you didn't have to rely on that extra stress, right? What if you're, what if you didn't give equal weight to every thought that came into your mind? What if you weren't laying awake all night thinking about, you know, what color dishes you'd use for a Thanksgiving Day party and you'd lay down and actually just went right into a deep delta wave of sleep? I mean, just think of the impact that that would have on the balance of your lifetime. And you may be one simple supplement away from that. Not s-

Joe Rogan 49:51 I have never thought of it that way. I'm gonna be honest with you. I've never thought-

Gary Brecka 49:54 (laughs)

Joe Rogan 49:54 ... that thinking would be connected so inextricably to diet deficiencies.

Gary Brecka 50:01 No question, because it's, n- Because what is thinking? It's this, very often, it is this release of these catecholamines into the brain, ephedrine, norepphedrine, um, epinephrine, dopamine, one, one of which we call adrenaline. And so, you don't need a massive dump like a fight or flight response. You just need to have them rise and not be able to break them down at the right rate, e- ****** state.

Joe Rogan 50:28 So for someone who has a, a very hard time going to sleep at night, like what would be a good supplement for them?

Gary Brecka 50:34 Um, SAMe, magnesium three and eight, um-

Joe Rogan 50:37 What i- what is SAMe?

Gary Brecka 50:38 S-adenosylmethionine. S-A-M, capital S-A-M, little e. So, SAMe, S-adenosylmethionine.

Joe Rogan 50:46 I'm gonna write this down too.

Gary Brecka 50:48 (laughs)

Joe Rogan 50:48 Now that I have a hard time... I don't have a hard time, my wife does.

Gary Brecka 50:51 Does she?

Joe Rogan 50:51 Yeah, she has a hard time going to sleep. I, I can sleep on her.

Gary Brecka 50:53 Then I should do this-

Joe Rogan 50:54 The floor of a moving train.

Gary Brecka 50:56 I'll look at, I'll do a cheek swab on her and I'll tell you exactly what she's deficient in.

Joe Rogan 51:00 SAMe. Okay.

Gary Brecka 51:03 So, S-adenosylmethionine is very commonly ... um, it's, it's one of the most highly required methylated nutrients in the human body. We, we also make SAMe and eventually homocysteine breaks down to methionine, and then, uh, uh, eventually S-adenosylmethionine, which goes into the brain and helps quiet the brain. And so, we need certain raw materials, methylated nutrients, to perform certain basic functions, right? Remember that the majority of our neurotransmitters are right here.

Joe Rogan 51:32 Mm-hmm.

Gary Brecka 51:32 I think 90% of the serotonin in your body is here. If you don't have it here, you can't have it here.

Joe Rogan 51:37 Right.

Gary Brecka 51:37 So, rarely do serotonin imbalances start here. They usually start here. And so, by, by taking a methylated multivitamin, which is very simple to get, um, methylated folate, a complex of B vitamins, SAMe, trimethylglycine if you have ho- high homocysteine, you have a shot at feeling the difference between good and great. I, I mean, I think most people are walking around right now at about 60% max of their true state of normal.

Joe Rogan 52:05 Hmm.

Gary Brecka 52:05 They just accepted such an erosion of their baseline sense of normalcy, they've forgotten what it feels like to be normal. They're like, "I'm just supposed to not sleep that well. Um, I'm supposed to get a great idea in the bedroom and walk through the kitchen and wonder what the hell I'm doing in the kitchen. Um-"

Joe Rogan 52:18 Hmm.

Gary Brecka 52:19 "... You know, I'm supposed to have this little m- bit of weight gain or water retention around. I'm not really supposed to be responding to exercise in my 40s or my 50s." And none of that is true. None of that is true. You don't th- these are not consequences of aging, they're consequences of missing raw material in the human body.

Joe Rogan 52:34 Wow. So for, for people that suffer from anxiety, what would be the th- like so if you wanted to look for some sort of a genetic component to these people having anxiety, what would you look for?

Gary Brecka 52:50 I would first highly s- suspect methylfolate deficiency. Now, if there are anxiety, if you sit down with them and they say, "No, I haven't had it on and off throughout my lifetime." "Okay, when do you get anxiety?" "Okay, I'm claustrophobic. Every time I step on a crowded elevator I get anxiety." That's different.

Joe Rogan 53:05 Right.

Gary Brecka 53:05 Or, "I'm afraid of heights and every time I walk to the thir- edge of a 30th floor balcony and look over, I get, I get massive anxiety."

Joe Rogan 53:10 Right.

Gary Brecka 53:11 That's different. What I'm talking about-

Joe Rogan 53:12 That's fairly normal.

Gary Brecka 53:13 That's fairly normal, right? These situational anxieties. But generalized anxiety, idiopathic anxiety-

Joe Rogan 53:19 Illogical anxiety.

Gary Brecka 53:20 ... illogical anxiety, you know, all these conditions that people are told they have, right? And, and, and then they're tall- taught coping mechanisms. B- I am by no means against bu- um, uh, against, you know, therapy or counseling, I think those can be some of the most beneficial things that anybody doe- does, they're signs of strength. But the majority of what we teach people to do with anxiety is cope with it. Here's how you deal with it: you breathe, you get a g- um, you know, you learn to, to get a therapist, you avoid certain situations, you modify your lifestyle. We rarely say, "Why don't we supplement for the breakdown of catecholamines, fight or flight neurotransmitters, which are associated in, in urinary excretions with anxiety? Why don't we supplement for the proper breakdown of catecholamines and just see what happens?" And you watch people's anxiety eviscerate. Um, magnesium, um, calcium, um, gluconate, uh, hydroxycobalamin, this, this, uh, a sp- specific form of B12. Um, you know, when, when you take a complex of B vitamins, a certain form of B12, methylcobalamin, hydroxycobalamin, methylfolate, and you put it into these bodies and they start breaking down catecholamines for the first time and getting rid of them, they may, for the first time in their adult lifetime, be anxiety-free and be like, "What in the hell did I wait so long for?" (laughs)

Joe Rogan 54:43 Wow. So the complex of B vitamins, if someone's looking for a complex of B vi- B vitamins, like what specifically does, does it have to have in it?

Gary Brecka 54:51 Um, uh, pyridoxine, riboflavin-

Joe Rogan 54:58 Spell that, pyridoxine? How do you spell that?

Gary Brecka 55:00 P-Y-R-O-D-I-X-I-N-E, pyridoxine. And it's, it's a form called pyridoxal 5'-phosphate, but pyridoxine, riboflavin, thiamin, niacin, pantothenic acid. Now, m- if you look at a B complex, it should contain all of those things. Y- it... By virtue of the fact that it's a B complex. If you go to a good vitamin manufacturer, um, you, th- you should see that their B complex is pyridoxine, riboflavin, thiamin, niacin, pantothenic acid and then you'll see little f- certain forms of it. The one thing you wanna avoid like the plague in the B12 category, and I get a lot of shit for this, but is a form of B12 called cyanocobalamin.

Joe Rogan 55:48 How do you spell that?

Gary Brecka 55:49 C-Y-A-N-O-C-O-B-A-L-A-M-I-N, cyanocobalamin. Can we pull something up on here?

Joe Rogan 55:59 Sure.

Gary Brecka 55:59 Um, can you go to G- Google?

Narrator 56:01 Mm-hmm.

Gary Brecka 56:02 'Cause before everybody climbs all over me and says it's... It's, it's a... Basically it's a cyanide-based form of B12, right? It, um, rarely occurs naturally in nature. It's, it's... You know, the, the most bioavailable forms are called methylcobalamin, hydroxycobalamin, um, and adenosylcobalamin, but-

Narrator 56:22 Well, what do we need to look up?

Gary Brecka 56:23 Oh, um, are we gonna be able to see it or not?

Joe Rogan 56:26 Yeah.

Gary Brecka 56:26 Oh, okay. Um, just go to Google and put in cyanocobalamin, C-Y-A-N-O.

Narrator 56:32 I already did.

Gary Brecka 56:33 Okay, cyanocobalamin, um, and then put a space and put the word PubChem. So, I'm just gonna take you to the National Library of Medicine. Just click on that first link. So, I'm gonna take you to the National Library of Medicine at the N- National Institute of Health. You can go here. We're on their, uh, public chemical site and you can look up this form of B12. You see how it says cyanocobalamin B12? Can you scroll down to section 5.3? So, if I want to see the component compounds, like, "What is this made out of?" I can go right here to section 5.3 and I can look at its component compounds. Can you click on hydrogen cyanide? (clicks tongue) So, this is a flammable, acute toxic health hazard, environmental hazard. By the way, this is the most common form of B12 in the world, right? We-

Joe Rogan 57:16 What?

Gary Brecka 57:16 ... we put this in Flinstone vitamins, we put it in all kinds of vitamins. The body can't even use this, so it has to be converted into hydroxycobalamin. It's astounding that we're allowed to do this, right? Because in the US we use something called single-dose toxicity to determine whether or not something is dangerous for you, right? And people that say things like, "The dosage determines the poison," that is, that is pathetically nonsensical because nobody gets mercury poisoning from a single, um, you know, allowable dose of, of mercury. Nobody gets, um, chemical poisoning from small... Uh, a single small dose of a chemical. But let's go down here and go to, um... Go to View More at the bottom. So, just, just read that sentence right there. See, h- hydrogen cyanide is a highly toxic... See that?

Joe Rogan 58:04 Yeah, highly toxic congelate... Conjugate-

Gary Brecka 58:07 Yeah.

Joe Rogan 58:07 ... acid of cyanide that is used as chemical weapon agent. (laughs) What?

Gary Brecka 58:11 Yeah. That's what we get our B12 from.

Joe Rogan 58:12 It's characterized as a colorless gas or liquid. What? So, if you're taking B12 supplements and they have that in it-

Gary Brecka 58:19 Mm-hmm.

Joe Rogan 58:20 ... you're getting this?

Gary Brecka 58:21 You're getting that.

Joe Rogan 58:22 And you're essentially taking poison.

Gary Brecka 58:24 Essentially. You're taking cyanide-based B12. The argument is, it's not enough cyanide to cause harm, right? So... Which I agree, but there's safe levels of mercury, there's safe levels of fluoride. We... Our, our water is full of fluoride, our toothpaste is full of fluoride. But if you go look at the fluoride studies in 3,600 municipalities around the United States, there's an inverse relationship between the concentration of fluoride and the IQ.

Joe Rogan 58:47 Yeah, low IQ.

Gary Brecka 58:48 As fluoride goes up-

Joe Rogan 58:49 Yeah.

Gary Brecka 58:49 ... IQ goes down.

Joe Rogan 58:50 But-

Gary Brecka 58:50 Especially in pregnant women's teeth.

Joe Rogan 58:50 ... yeah, we talked about that on the podcast recently. We were trying to figure it out, like, "What the fuck is fluoride doing in the water?"

Gary Brecka 58:55 It's a neurotoxin, right? It actually... I think it was originally fluorohexine which actually was a byproduct of fertilizer production, and they realized that when they kept the fluorohexine in the fertilizer, it killed the seed. So, they pulled it out and they wondered, "Well, what the hell are we gonna do with all this fluorohexine? Well, I guess we'll convince water municipalities to put it into the water, because there's a marginal amount of evidence that it can create a nanoparticulate layer over the enamel and it could potentially prevent tooth decay."

Narrator 59:21 (laughs)

Gary Brecka 59:21 Ashame on them.

Joe Rogan 59:21 But you should just brush your teeth.

Gary Brecka 59:23 Or you could just brush your teeth. Right?

Joe Rogan 59:25 Yeah.

Gary Brecka 59:25 It's, it's astounding to-

Joe Rogan 59:26 The way I would describe it, I said it's like putting sunscreen in apples, because some people get cancer.

Narrator 59:32 (laughs)

Gary Brecka 59:33 (laughs)

Joe Rogan 59:33 So you should just... Every, every apple should have sunscreen in it.

Gary Brecka 59:37 Right. (laughs)

Joe Rogan 59:37 It's really that dumb.

Gary Brecka 59:38 It is that dumb. And, and, you know, when you, when you look at it, it's like... I- uh, I was looking at the back of some of these... I, I, I did a post on this the other day, I was looking at the back of these toothpaste labels and it literally says to call poison control if you swallow it.

Joe Rogan 59:52 What?

Gary Brecka 59:52 Fluoride toothpastes, it says, "If swallowed, contact poison control."

Joe Rogan 59:56 Oh my God.

Gary Brecka 59:56 But you get four times that dosage in s- in, in, in eight eight-ounce glasses of water in a day if you drink tap water. And so, you know, one of the things I tell people to permanently get out of their life besides GMO foods is tap water. Like, today should be the day that you never drink tap water again, right? Because it-

Joe Rogan 1:00:14 Yeah, 'cause I have-

Gary Brecka 1:00:15 ... fluoride poisoning.

Joe Rogan 1:00:15 ... a friend who lives in New York City, he's like, "New York City has the best tap water." I said, "Shut the fuck up."

Gary Brecka 1:00:19 Yeah. (laughs)

Narrator 1:00:19 (laughs)

Joe Rogan 1:00:19 "You should never drink that shit."

Gary Brecka 1:00:20 Yeah.

Joe Rogan 1:00:20 And I was trying to explain to him about fluoride and it goes in one ear, out the other. You sound like a kook.

Gary Brecka 1:00:26 You d- Yeah, you do.

Joe Rogan 1:00:27 "Fluoride's bad. Fluoride's good for your teeth." Like, w- how do you know?

Gary Brecka 1:00:30 Yeah.

Joe Rogan 1:00:30 Why are you saying that? Do you know what's bad for you?

Gary Brecka 1:00:32 Yeah.

Joe Rogan 1:00:32 What? Fluoride's bad for you. Fluoride's associated with low IQ.

Gary Brecka 1:00:36 Yes.

Joe Rogan 1:00:36 Do you know the higher the dose of fluoride in the drinking water, the lower the town IQ is? For real.

Gary Brecka 1:00:41 Yeah.

Joe Rogan 1:00:41 And people go like, "Yeah, come on. Why would they do that?"

Gary Brecka 1:00:44 Yeah. Yeah, it's a neurotoxin.

Joe Rogan 1:00:45 Right. But why are they still dumping that sh- Is it just some sort of a predatory relationship that they ha- the fluoride manufacturers have?

Gary Brecka 1:00:51 Well, I mean, now think of the position that you're in. You're a municipality and like, "Well, guys, we've been giving you this fluoridated water for 25 years and it's, uh, cancer-causing neurotoxin. We're gonna go ahead and pull that out." Imagine what that would... I mean, it's public panic.

Joe Rogan 1:01:02 But that's real.

1:01:03 – 1:17:25

Seed oils, fluoride, and “fact-checking”: distrust of institutional narratives

Gary Brecka 1:01:03 ... it's f-... it's absolutely real. You know, I got censored all over Instagram the other day for, for posting about seed oils. It's the same thing. I was like, "Look, guys. I didn't say particularly seed oils are bad for you. What I did say was industrial processed seed oils are bad for you." If you put a canola plant in a commercial press and it comes out gummy, and then you take that gummy canola plant and you, and you de-gum it with hexane, which is a known neurotoxin, and then you take that de-gummed oil and you heat it to 405 degrees and turn it rancid, so now you have a, a rancid neurotoxic, um, um, oil. And then you, and then you take that rancid neur- neurotoxic oil and you deodorize it with sodium hydroxide, um, which is a known carcinogen, um, and then occasionally you, you, you bleach it so, so you, you clear the liquid, then you bottle it and put it on the shelf, that is horrible for you. In fact, that's the pro-... that's the problem with the majority of our food supply is that it's not the food itself, it's the distance from the food to the table. Right? I mean, everybody vilifies meats, but if you look at grass-fed meats versus in- industrial raised cattle, they're night and day. They're completely different chemicals.

Joe Rogan 1:02:05 Yeah, but, so with seed oils, what happened? You got censored on Instagram?

Gary Brecka 1:02:11 I got fact-checked.

Joe Rogan 1:02:12 Fact-checked?

Gary Brecka 1:02:12 Yeah, so if you go into my Instagram, it has that, you know, it has that little blank page over it.

Joe Rogan 1:02:16 Can we go to that?

Gary Brecka 1:02:16 Yeah.

Joe Rogan 1:02:17 I wanna see this fact-check.

Gary Brecka 1:02:18 Oh, sure.

Joe Rogan 1:02:18 'Cause these fact-check motherfuckers are horrible.

Gary Brecka 1:02:21 Oh, yeah. So go to my, uh, @garybrecka, and then you go to my, um, reels, and it's about 20 reels down. You'll see the little clouded fact-check thing they put over top of it.

Joe Rogan 1:02:32 Hmm.

Gary Brecka 1:02:32 And it says, um, "False information. See why." And then you have to click through and then it says, um, "Food-grade, uh, seed oils are not toxic for human beings, experts say." I'm like, "Well, I'd love to debate that expert." I really-

Joe Rogan 1:02:48 Can we go to that, Jimmy?

Narrator 1:02:48 Hold on. I'm, I'm looking, I'm looking, I'm looking.

Joe Rogan 1:02:50 What would the post say? What is the post?

Gary Brecka 1:02:53 Well, y- y-... it's gonna say, "False information." It's gonna be kind of blanked out.

Joe Rogan 1:02:56 Right. But what is the post that you wrote? What does it say? What does it look like-

Gary Brecka 1:02:59 It's seed oils.

Joe Rogan 1:02:59 ... so you can find it? Just seed oils?

Gary Brecka 1:03:00 Um... Yeah, seed oils.

Joe Rogan 1:03:01 Recently?

Gary Brecka 1:03:02 Um, it's probably a few months ago now. But it's still on there. Just go to my, um, reels, not my stories, and you'll see it on there.

Narrator 1:03:09 How? 'Cause, you know, a few just saw it.

Gary Brecka 1:03:11 Yeah. Yeah.

Narrator 1:03:12 There's your reels. I don't know if-

Gary Brecka 1:03:13 All right, keep going. Down, down, down. Down, down, down. It's right around here. Keep going.

Narrator 1:03:21 There's seed oils right here.

Gary Brecka 1:03:22 No, that's... That one they didn't catch.

Narrator 1:03:24 Okay. (laughs)

Gary Brecka 1:03:25 Go to the... Yeah. Keep going. (laughs) Yeah.

Joe Rogan 1:03:28 I wonder how they do catch it.

Gary Brecka 1:03:29 I don't know either, man. I don't know how these fa-... Okay, now we're getting into it around here somewhere. Keep going. It has a little, uh... Keep going. It's pretty obvious when you see it, 'cause it's cloudy and, uh, it doesn't say.

Joe Rogan 1:03:43 The image itself is cloudy because you can't, like, click through it?

Gary Brecka 1:03:44 Yeah, like you can't... It's fuzzy. They fuzz the image out. Um-

Joe Rogan 1:03:48 Interesting.

Gary Brecka 1:03:49 Yeah, they'll fuzz it out.

Joe Rogan 1:03:50 Is that it right there?

Gary Brecka 1:03:51 No, that's smoke.

Narrator 1:03:51 No, that's, that's the UFC. Hold on. I don't know if it shows that way on the web. Maybe.

Joe Rogan 1:03:56 Interesting.

Gary Brecka 1:03:56 I don't think it's that far back. Keep going.

Narrator 1:03:58 Yeah, so I haven't... I'm pretty far back now.

Gary Brecka 1:04:00 You are? All right, kee- keep scrolling up. You probably went past it. But you'll see, they put a thing over top of it. Hold on. Keep s-

Narrator 1:04:06 I don't know if that happens on the, uh, website version of Instagram.

Gary Brecka 1:04:10 Oh. Well, I'm sure they fact-check it on there too. Um, no, it's not gonna be in the alt and human stuff. Um-

Joe Rogan 1:04:19 Scroll down a little bit, Jimmy.

Narrator 1:04:20 Mm-hmm.

Gary Brecka 1:04:23 Let me see. Keep going. Oh, it's about maybe two, three months ago.

Narrator 1:04:31 Well, this one-

Joe Rogan 1:04:31 So it's before that seed oil one.

Gary Brecka 1:04:33 Yeah. Before that one. They didn't catch that one.

Narrator 1:04:35 So that was five months ago.

Gary Brecka 1:04:36 It was before that one. Uh, so it's be-

Narrator 1:04:38 That was before that? That'd be s-

Gary Brecka 1:04:39 Yep, it was before that.

Narrator 1:04:39 Okay, so this is, then, six months ago.

Gary Brecka 1:04:44 See, even on there. Probably somewhere in there.

Joe Rogan 1:04:45 I'm just very-

Gary Brecka 1:04:45 I thought it was-

Joe Rogan 1:04:46 ... curious to see-

Gary Brecka 1:04:46 Yeah, no. I wanna show it to you too so you c-

Joe Rogan 1:04:48 ... what the experts say when you click the link.

Gary Brecka 1:04:49 These are the... These are my reels?

Narrator 1:04:51 Yes, sir.

Gary Brecka 1:04:51 Okay. Keep going down. 'Cause it was on a podcast I did with, uh, Bradley.

Joe Rogan 1:04:58 Infrared sauna, perfect aminos.

Gary Brecka 1:05:00 Yeah.

Narrator 1:05:00 This is seven, eight months ago?

Gary Brecka 1:05:03 Flight travel stuff. Keep going. Maybe it got pushed down further.

Narrator 1:05:07 Health and wellness.

Gary Brecka 1:05:07 Yeah.

Narrator 1:05:08 UFC. Super Bowl.

Gary Brecka 1:05:10 I'm sure I... I could find it on my phone if I had my phone.

Narrator 1:05:12 That's what I'm saying. It's... I don't think-

Gary Brecka 1:05:13 But I'll show it to you.

Narrator 1:05:14 ... it just shows on the website.

Gary Brecka 1:05:14 It's okay.

Narrator 1:05:15 It's like, that was my point.

Joe Rogan 1:05:15 Yeah.

Gary Brecka 1:05:15 So-

Narrator 1:05:16 They, they-

Joe Rogan 1:05:16 Yeah. But-

Narrator 1:05:16 ... they blank it out and it has a little thing over it, and then it says, "False information. See why."

Joe Rogan 1:05:20 Right.

Gary Brecka 1:05:20 And then it says, "Fact-checkers say seed oils are not bad for human beings."

Joe Rogan 1:05:24 Yeah.

Gary Brecka 1:05:24 Mm-hmm.

Joe Rogan 1:05:24 No, I've, I've seen people argue that too.

Gary Brecka 1:05:27 Mm-hmm.

Joe Rogan 1:05:28 And I'm like, "At what doses and for how long?" Because they're ubiquitous.

Gary Brecka 1:05:31 Mm-hmm.

Joe Rogan 1:05:31 They're in everything. So many people are consuming seed oils.

Gary Brecka 1:05:34 Right.

Joe Rogan 1:05:34 And they really are industrial lubricants.

Gary Brecka 1:05:36 Right.

Joe Rogan 1:05:36 That's... They, they essentially repurpose them for human use because they had a bunch of it laying around.

Gary Brecka 1:05:41 So true.

Joe Rogan 1:05:42 Yeah.

Gary Brecka 1:05:42 Crisco.

Joe Rogan 1:05:43 Yeah. And it's not good for you-

Gary Brecka 1:05:44 No.

Joe Rogan 1:05:44 ... by any stretch of the imagination. So when they said that seed oil... Are there any seed oils that are okay for you?

Gary Brecka 1:05:52 I mean, c-... a certain cold processed seed oils. I mean, I, I, I eat olive oil. I think you need-

Joe Rogan 1:05:57 Olive oil. But olive oil's... Like, you don't think of that as industrialized seed oil.

Gary Brecka 1:06:00 No.

Joe Rogan 1:06:00 It's been cold pressed.

Gary Brecka 1:06:00 And you have to watch that too, 'cause sometimes they'll put palm oil and-

Narrator 1:06:03 What does it say? Post show on the...

Joe Rogan 1:06:04 Oh, you found it?

Narrator 1:06:04 On the phone, it shows that.

Gary Brecka 1:06:06 Yeah.

Narrator 1:06:06 It says-

Joe Rogan 1:06:06 So then you see it?

Narrator 1:06:07 ... uh, fact checker lead story's conclusion false. Fact check, food-grade canola oil is not toxic for humans, experts say. That's the link that they give.

Joe Rogan 1:06:15 (laughs) That's it? Experts say.

Gary Brecka 1:06:18 But see how they have that, that blank-

Joe Rogan 1:06:19 Uh-huh.

Gary Brecka 1:06:19 ... over there? So you can't even read it.

Joe Rogan 1:06:21 Right. You can't go through it.

Gary Brecka 1:06:22 See? My face-

Joe Rogan 1:06:23 Yeah.

Gary Brecka 1:06:23 ... is all blocked out.

Joe Rogan 1:06:24 Well, I... There's a lot of things that I follow that have that, unfortunately.

Gary Brecka 1:06:27 Yeah. (laughs)

Joe Rogan 1:06:28 It's-

Gary Brecka 1:06:29 You got it for a little while. (laughs)

Joe Rogan 1:06:30 Yeah.

Gary Brecka 1:06:30 I saw you.

Joe Rogan 1:06:31 It's wi- it's w- it's wild now.

Gary Brecka 1:06:32 It's so crazy.

Joe Rogan 1:06:34 It really is wild.

Gary Brecka 1:06:34 It's so crazy. I mean, I-

Joe Rogan 1:06:36 Because there's so many corrupting factors that are changing the way people have access to information.

Gary Brecka 1:06:41 Yeah.

Joe Rogan 1:06:41 And they're not getting accessed to accurate information, and they use that fucking appeal to authority, "Experts say."

Gary Brecka 1:06:46 Mm-hmm.

Joe Rogan 1:06:47 What experts? I, I-

Gary Brecka 1:06:48 Please put this expert on, across the table.

Joe Rogan 1:06:49 Are they being paid off? Are they the same experts that the sugar industry fucking bribed in the '50s-

Gary Brecka 1:06:54 Yeah.

Joe Rogan 1:06:55 ... to tell people that saturated fat is bad for you?

Gary Brecka 1:06:57 Yeah.

Joe Rogan 1:06:57 'Cause to this day, p- people still believe that. It's wild.

Gary Brecka 1:07:00 I, I just did an explanation of what the mRNA vaccine was. I didn't even attack the mRNA vaccine. I just explained to people, 'cause people didn't understand this.

Joe Rogan 1:07:08 Here it is.

Gary Brecka 1:07:08 Oh, yeah. Boom.

Joe Rogan 1:07:08 False information. See why.

Gary Brecka 1:07:10 Reviewed by independent fact checkers.

Joe Rogan 1:07:12 By the way, that's horse shit. There's no independent fact checkers.

Gary Brecka 1:07:16 Right.

Joe Rogan 1:07:16 They're not independent.

Gary Brecka 1:07:18 No, that's very true.

Joe Rogan 1:07:18 It's horse shit. They, they have a fucking mandate.Okay. So click on that so we can just hear what he's saying.

Gary Brecka 1:07:25 ... sunflower seeds. Aren't those good for you?

Narrator 1:07:29 These seed oils are terrible, man. If you actually saw how, um, something like a canola oil was processed, right? I mean, when they actually first make canola oil, the oil comes out very, like, thick and gummy. So they use-

Joe Rogan 1:07:39 This is what you just described.

Gary Brecka 1:07:40 Yeah, just what he described. Yeah. ... to de-gum these seeds.

Joe Rogan 1:07:43 So that ... But none of this that you're saying is not true.

Gary Brecka 1:07:46 No.

Joe Rogan 1:07:46 So when you click see why, what ... where does it take you, Jamie?

Narrator 1:07:50 Well, it just ... Oh, I can't-

Gary Brecka 1:07:51 Wow.

Joe Rogan 1:07:51 It doesn't?

Narrator 1:07:52 Let me bring it back up.

Gary Brecka 1:07:53 Well, when you say see why-

Joe Rogan 1:07:54 So see why.

Gary Brecka 1:07:56 ... it just says that.

Joe Rogan 1:07:57 That's all it says, "False."

Gary Brecka 1:07:59 It just says, "False." (laughs)

Joe Rogan 1:08:01 "Fact checked. Food-grade canola oil is not toxic for humans." Not done as Paul Saladino.

Gary Brecka 1:08:06 Oh, they hammer Paul Saladino too.

Joe Rogan 1:08:07 Is food-grade canola oil for, toxic for humans since it starts with the seeds of a rape plant? No one's saying that. By the way, it's not a rape plant. It's rape seed oil. No one, no one calls it the rape plant.

Gary Brecka 1:08:19 (laughs) I know. Seeds of a rape plant.

Joe Rogan 1:08:20 That's so crazy.

Gary Brecka 1:08:21 Which is complete truth.

Joe Rogan 1:08:22 No, it's not true. In the United States, the Food and Drug Administration, which, by the way, has never been known to be corrupt-

Gary Brecka 1:08:28 Yeah. (laughs)

Joe Rogan 1:08:28 ... which sets food regulations, recognize canola oil as safe for human consumption. Well, furthermore, a Tufts University nutrition scientist told Lead Stories this ... Who is this fucking person? You just ... A Tufts University nutrition science, scientist?

Gary Brecka 1:08:43 Yeah.

Joe Rogan 1:08:43 Told Lead Stories, "There's no basis for the claim that food-grade canola oil is unsafe for humans to consume. In fact, evidence suggests that canola oil may benefit heart health." The claim about canola oil's toxicity appeared in a video posted on Instagram December 25th, 2022. In that video, an unidentified on-camera narrator claimed-

Gary Brecka 1:09:06 Paul Saladino. (laughs)

Joe Rogan 1:09:07 ... canola oil is toxic. Here's how it's made. So it tells you that, da, da, da, da, da, da. There's Paul.

Gary Brecka 1:09:13 (laughs)

Joe Rogan 1:09:13 Look at him looking guilty.

Gary Brecka 1:09:15 Looking guilty.

Joe Rogan 1:09:15 The claim that canola oil, uh, is a, is an old canard. In 2019, for instance, Lead Stories debunked a claim that canola oil causes brain damage, dementia, and weight gain. In January 4th of 2023, email to Lead Stories, Alice H. Lichtenstein, Director a- and Senior Scientist of the Cardiovascular Nutrition Laboratory at Tufts University Friedman School of Nutrition, Science, and Policy, emphasized the claims that food-grade canola oil is toxic for humans are untrue. There's no basis on which to claim that any canola oil on the market contains uric acid or the oil extract- extracted in any way that is different from other plants-

Gary Brecka 1:10:00 Oh, my God.

Joe Rogan 1:10:00 ... such as soybean oil. So what are you getting outta this?

Gary Brecka 1:10:02 Look, canola oil is made by a process of chemical refinement called RBD, refined, bleached, deodorized.

Joe Rogan 1:10:09 Yeah.

Gary Brecka 1:10:09 Which involves the use of hexane, which is what I was just talking about.

Joe Rogan 1:10:12 Yeah.

Gary Brecka 1:10:12 A volatile solvent with low toxicity. Okay. Refined, bleached, and deodorized.

Joe Rogan 1:10:18 And it's been used to extract oils from seeds since the 1930s, right when people started catching cancer a lot quicker. (laughs)

Gary Brecka 1:10:24 Yeah.

Joe Rogan 1:10:25 This article, canola, Canola Council of Canada-

Gary Brecka 1:10:29 It even says hexane.

Joe Rogan 1:10:30 It's an article from the Canola Council of Canada.

Gary Brecka 1:10:33 (laughs)

Joe Rogan 1:10:33 Two things I don't trust, the Canola Council and Canada.

Gary Brecka 1:10:36 And Canada. (laughs)

Joe Rogan 1:10:37 Seed oils are first crushed to express the oil, and the seed oil is extracted from low-boiling solvent like hexane. Deodorization is the final step. Whenever you have to fucking deodorize food, like-

Gary Brecka 1:10:47 Mm-hmm.

Joe Rogan 1:10:47 ... what are you doing? That's not an armpit.

Gary Brecka 1:10:50 Yeah.

Joe Rogan 1:10:50 It's salad dressing. (laughs)

Gary Brecka 1:10:52 E- exactly.

Joe Rogan 1:10:53 Why are you old deodorizing your fucking salad dressing?

Gary Brecka 1:10:53 And by the way, if hexane, a known neurotoxin-

Joe Rogan 1:10:56 Yeah.

Gary Brecka 1:10:57 ... um, we just use a little bit of it. Right? An- an- this is, this is the thing that we do in this country. We have something called, um, uh, w- we have com- something called single-dose toxicity, which means that, you know, if this capsule has a certain amount of arsenic in it, but it's not enough to cause a toxic reaction, then I can still give it to you.

Joe Rogan 1:11:13 Mm-hmm.

Gary Brecka 1:11:14 But it's the cumulative dose toxicity most European countries use, which is why, um, a- there are dozens of compounds that are legal in the United States that aren't legal anywhere else on the surface of the Earth. They're certainly not legal in Europe. Um, they don't use folic acid in Europe. They don't use cyanocobalamin. Um, actually, cyanocobalamin, I'm not sure if it's actually been banned.

Joe Rogan 1:11:32 God damn it, Jamie. We have to move to Europe.

Gary Brecka 1:11:35 I know.

Joe Rogan 1:11:35 Do we have to move to Europe?

Narrator 1:11:37 I don't know. I'm more interested on, like, how a small website like this becomes-

Joe Rogan 1:11:40 (laughs)

Narrator 1:11:41 ... the verified faction.

Gary Brecka 1:11:42 I know, the verified faction. (laughs)

Joe Rogan 1:11:43 They get fucking paid. They get fucking paid.

Narrator 1:11:45 That's why I was just describing it.

Gary Brecka 1:11:46 The Canola Oil Society declines.

Joe Rogan 1:11:47 Yeah. Like, there's so many of these websites that are in cahoots with big businesses. It's horse shit.

Gary Brecka 1:11:54 Yep.

Joe Rogan 1:11:54 These independent fact checkers are not independent, and they're not checking facts.

Gary Brecka 1:11:58 Right.

Joe Rogan 1:11:58 They're just spewing propaganda.

Gary Brecka 1:12:00 Well, it's, it's astounding too that you can actually be from the Canola Soc- Society defending the canola facts.

Joe Rogan 1:12:05 It's hilarious.

Gary Brecka 1:12:06 Yeah. Um, but-

Joe Rogan 1:12:07 It really is hilarious.

Gary Brecka 1:12:09 And, and, and again, the sa- same as with, with, with fluoride. So, you know, the, these ... It's, it's all of these little microtoxicities, right, that are, that, that are adding up. I mean, y- you know, when you look at cellular metabolism and how it's interrupted by all of these microtoxins, one of the reasons why people, when they go on certain types of, of diets, like a carnivore diet, experience such a dramatic improvement in health is because the majority of what's happening is they're removing a lot of these toxic chemicals.

Joe Rogan 1:12:36 Makes sense.

Gary Brecka 1:12:36 Right? Improving their mitochondria function.

Joe Rogan 1:12:37 By the way, should we change the name of rape seed?

Gary Brecka 1:12:40 I know. (laughs)

Joe Rogan 1:12:42 (laughs) You know? Do we, do we have a murder fruit? You know, like what the fuck?

Gary Brecka 1:12:44 Yeah, exactly.

Joe Rogan 1:12:45 Why is ... Why are they calling it that? An- wh- how is it the same thing as canola?

Gary Brecka 1:12:48 Like a domestic violence seed.

Joe Rogan 1:12:50 Right. Because you think of canola, you think of corn.

Gary Brecka 1:12:52 Yeah, palm kernel s- sunflower sounds great.

Joe Rogan 1:12:55 Yeah.

Gary Brecka 1:12:55 But, uh, rape seed.

Joe Rogan 1:12:57 But all of those s- seeds, saffli- uh, safflower oil, sunflower or sunseed oil, sunflower seed, all those seeds are bad.

Gary Brecka 1:13:06 All the seeds are bad.

Joe Rogan 1:13:06 All those seed oils are bad. Not that sunflower seeds are bad for you.

Gary Brecka 1:13:09 Right.

Joe Rogan 1:13:10 But those seed oils are bad due to the process, due to the hexane, due to the deodorizers.

Gary Brecka 1:13:15 Yeah, the polyunsaturated fatty acids. I mean, this is what causes the oxidation, you know, in, in cholesterol. You know, it gets oxidized and it actually starts the atherosclerotic ar- um, you know, process that starts the, the plaquing and the scarring, and it actually makes these, um ... You know, it turns them into free radicals.

Joe Rogan 1:13:31 So you're saying that seed oils themselves cause the plaquing?

Gary Brecka 1:13:35 Seed oils themselves cause the oxidation of cholesterol, which leads to, to plaquing. You know, the cholesterol really gets vilified, right? I mean, LDL cholesterol. And I mean, there's very little evidence linking LDL cholesterol on its own-... to cardiovascular disease. Now, there are some apolipoprotein As, apolipoprotein Bs, but when we- y- you look at your, your, your blood work and you see that your LDL cholesterol is marginally high. You know, let's say that it, it s- should be 99 or less and you're 109 and, and they say, "Well, you should go on a statin." I mean, marginally elevated cholesterol, when we were in the, when we were in the mortality space was a marker of longevity. At the time, what we would do is if you had low levels of triglyceride and you had elevated, marginally elevated LDL cholesterol and high HDL cholesterol, the high density lipoprotein, we would actually extend your life expectancy.

Joe Rogan 1:14:27 Really?

Gary Brecka 1:14:27 We would extend your life expectancy. If you were clinically in our, in, in, within these certain margins, if you were very low on cholesterol, like your LDL cholesterol was clinically pushed down ... Remember, cholesterol's not a fuel source, right? It's, it's ... The body can't use cholesterol for energy. It's a construction material, so we use it to build every cell wall, we use it to build cell membranes, we use it to make hormones. It's a very necessary construction material. Um, and it gets vilified because it's at the scene of a lot of crimes, but it's not pulling the trigger.

Joe Rogan 1:14:58 Mm.

Gary Brecka 1:14:58 Right? I mean, a more dangerous measure would be to have high cholesterol and very high triglycerides, because then you start to reduce the particulate size of cholesterol. You know, so remember like from high school geometry, as the size of a sphere gets smaller, its surface area to volume ratio goes up. And so a lot of these small particulate cholesterol are very dangerous because they pass through the arterial wall, they get kinda eaten by a macrophage, and they start this process of scarring. But just having elevated levels of LDL cholesterol was a marker for longevity, um, in, in the, our mortality space.

Joe Rogan 1:15:36 So, are there foods that when combined with high levels of dietary cholesterol ... Like, is, is there things that you should not eat while also consuming high levels of dietary cholesterol and they work together-

Gary Brecka 1:15:51 It's-

Joe Rogan 1:15:51 ... in a negative way?

Gary Brecka 1:15:52 Yeah, I mean, I, I'm not aware of any link between dietary cholesterol and serum concentration of cholesterol. Only 15% of the cholesterol in your bloodstream comes from diet. 85% of the cholesterol in your blood is manufactured by the liver. So, if you want to lower your cholesterol, we have to lower what we put into the front door of the liver.

Joe Rogan 1:16:10 Mm.

Gary Brecka 1:16:10 If you put high glycemic carbohydrates in the front door of the liver, you will likely ver- get not just high triglyceride, but also elevated levels of cholesterol out the back door.

Joe Rogan 1:16:20 So, elevated levels of cholesterol and high triglycerides are the problem disaster.

Gary Brecka 1:16:25 Disaster.

Joe Rogan 1:16:25 ... together?

Gary Brecka 1:16:25 Yeah.

Joe Rogan 1:16:26 And that comes from diet as well as ...

Gary Brecka 1:16:30 Sugar.

Joe Rogan 1:16:30 Sugar.

Gary Brecka 1:16:30 Yeah. I mean, sugar is the enemy. Right? I mean, so, you know, people that eat the most sugar have the highest blood fat. You know, if we go back to Dana White for a second, um, you know, he had, um, a life-threatening level of triglycerides when he was fasted. His triglycerides were around 800, which is very high.

Joe Rogan 1:16:48 For when he's fasted?

Gary Brecka 1:16:49 When he's fasted. For fasted state. Yeah, when he was fasted. And-

Joe Rogan 1:16:53 What was it like when he was eating?

Gary Brecka 1:16:54 Oof. I can't imagine.

Joe Rogan 1:16:56 Jesus.

Gary Brecka 1:16:56 But he also ate a lot of refined carbohydrates.

Joe Rogan 1:16:59 Yeah.

Gary Brecka 1:16:59 So now, re- remember, you know, this, this syndrome called metabolic syndrome, which is showing up in younger and younger and younger ages now, right, is this combination of, you know, m- abdominal fat, um, high triglyceride, high blood fat, um, high insulin, hyperinsulinemia, um, high levels of, of sugar, which is called hemoglobin A1C, the three-month average of your blood sugar, um,

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