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Instinct Raising $1B at $10B & Meta Launches Muse | Miro Sells for $1.36B After a $17.5B Valuation

Jason Lemkin is one of the leading SaaS investors of the last decade with a portfolio including the likes of Algolia, Talkdesk, Owner, RevenueCat, Saleloft and more. Rory O’Driscoll is a General Partner @ Scale where he has led investments in category leaders such as Bill.com (BILL), Box (BOX), DocuSign (DOCU), and WalkMe (WKME), among others. ----------------------------------------------- Timestamps: 00:00 - Intro 01:24 - Should Frontier AI Labs Be Forced to Slow Down? 06:04 - Is Anthropic Preparing Its Biggest IPO Risk Factor? 10:24 - What Happens if AI Becomes Impossible to Control? 17:46 - How “Pacing the Frontier” Could Hit AI Infrastructure 21:11 - Meta Enters the AI Assistant Race With Muse 27:21 - Can Standalone AI Assistants Beat Meta and OpenAI? 29:11 - Would You Invest in Instinct at $10BN? 32:08 - Why Meta Is the Biggest Threat to AI Assistant Startups 35:18 - Could Instinct Become a $50BN Acquisition? 42:16 - Miro Sells for $1.35BN After a $17.5BN Valuation 45:30 - The Bending Spoons Playbook: Raise Prices, Cut Costs 48:22 - Are We Entering the Era of SaaS Capitulation? 01:03:50 - Why Venture Is More Extreme Than Ever 01:06:38 - Mistral Raises €3BN: Europe’s AI Sovereignty Bet 01:10:32 - Adobe’s New CEO 01:15:55 - What Happens When Growth Companies Become Value Stocks? ---------------------------------------------------------------------------------------------- Subscribe on Spotify: https://open.spotify.com/show/3j2KMcZ... Subscribe on Apple Podcasts: https://podcasts.apple.com/us/podcast... Follow Harry Stebbings on X: https://x.com/harrystebbings Follow Jason Lemkin on X: https://x.com/jasonlk Follow Rory O’Driscoll on X: https://x.com/rodriscoll Follow 20VC on Instagram: https://www.instagram.com/20vchq Follow 20VC on TikTok: https://www.tiktok.com/@20vc_tok Visit our Website: https://www.20vc.com Subscribe to our Newsletter: https://www.thetwentyminutevc.com/con... ----------------------------------------------- Legal Disclaimer: The content of this podcast is for informational and entertainment purposes only and does not constitute financial or investment advice. Any discussion of stocks, public markets, or investment strategies reflects the personal opinions of the speakers and should not be relied upon when making investment decisions. Figures, valuations, and financial data referenced may be estimates or subject to error. Always consult a qualified financial adviser before making any investment decision. The views expressed are those of the individual speakers and do not represent the views of 20VC or its affiliates. ----------------------------------------------- #20vc #harrystebbings #roryodriscoll #jasonlemkin #muse #ai #anthropic #miro #instinct #meta

Rory O’DriscollguestHarry StebbingshostJason Lemkinguest
Sep 17, 20261h 19mWatch on YouTube ↗

At a glance

WHAT IT’S REALLY ABOUT

Frontier AI “pacing,” Meta’s Muse, and the new SaaS capitulation era

  1. The discussion opens with backlash to calls from Anthropic, OpenAI, and Elon Musk to “pace the frontier,” debating whether existential-risk rhetoric is credible, helpful, or a strategic move ahead of an Anthropic IPO.
  2. The hosts argue the most realistic AI dangers are cyber and “dual-use” misuse, while skepticism remains high about near-term mass unemployment claims and “10% doom” extinction probabilities.
  3. Meta’s Muse is reviewed as a high-quality AI assistant product whose speed, bundled compute, and distribution make it a uniquely serious competitor to standalone assistant startups.
  4. Instinct’s rumored $1B raise at a $10B valuation sparks a valuation-and-unit-economics debate: product demand and team strength versus infrastructure costs, latency, and incumbent pressure.
  5. The episode shifts to market structure: Miro’s $1.35B sale to Bending Spoons signals SaaS repricing and fewer exit paths, while Mistral’s mega-round highlights Europe’s push for AI sovereignty rather than frontier dominance.

IDEAS WORTH REMEMBERING

5 ideas

“If you can’t control it, don’t build it” is the core governance test for frontier AI.

Rory argues that if leaders credibly believe they’re building uncontrollable, world-ending tech, they have an ethical and managerial obligation to halt or radically constrain it—rather than outsource responsibility to governments or third-party monitors.

Anthropic’s safety messaging may be functioning like an IPO risk-factor rehearsal.

Jason frames Dario’s “pacing the frontier” comments as a proactive disclosure strategy: surface the scariest narratives early so they’re priced into public perception and investor materials before a major IPO process.

The “dark version” of AI is the mirror image of its best use cases.

They agree the most concrete near-term hazard is misuse: the same capabilities that accelerate coding, biology, and engineering can accelerate hacking, weaponization, and sabotage—especially as open-weight models spread.

Meta’s advantage is vertical integration: distribution + infra + model + product.

Meta’s Muse is praised as surprisingly polished and fast, aided by Meta’s owned infrastructure and in-house model, plus the ability to subsidize costly per-user compute in ways startups can’t match.

At $10B, Instinct looks less like a venture bet and more like an “M&A-or-bust” wager.

The panel is divided on Instinct at a $10B valuation: excitement about product pull and team quality clashes with concerns about high inference costs, sluggish latency, and the risk that success requires a massive acquisition.

WORDS WORTH SAVING

5 quotes

If the feds really thought that there was someone in downtown San Francisco building a technology that had a 10% chance of blowing up the world in the next 10 years, they would move in with a SWAT team, kill everyone in the place, and close it down.

Rory O’Driscoll

Market moves 0.1% on news of 10% probability of extinction. Capitalism took on board the risk and said, "It'll be fine."

Rory O’Driscoll

If you're building something that you can't control, then maybe you should stop building it, right? 'Cause you're the CEO.

Rory O’Driscoll

Most positive use cases for AI have a corresponding dark version. If you're superhuman at coding, you're superhuman at hacking.

Jason Lemkin

The real problem is that 10 or 15% of founders are sociopaths. They genuinely are.

Jason Lemkin

“Pacing the frontier” and AI regulation feasibilityAnthropic IPO risk narrative and public backlashDual-use AI and cyber/security threatsMeta Muse product quality and infra advantagesStandalone AI assistant startups vs incumbentsInstinct $1B raise at $10B valuation debateMiro sale to Bending Spoons and SaaS repricing/capitulation

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