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The Twenty Minute VCThe Twenty Minute VC

Sequoia Leaves London, Close Scout Program & End Evergreen Fund | NASDAQ Loses $2.5T in 24 hours

Jason Lemkin is one of the leading SaaS investors of the last decade with a portfolio including the likes of Algolia, Talkdesk, Owner, RevenueCat, Saleloft and more.

Jason LemkinguestHarry StebbingshostRory O’Driscollguest
Nov 12, 20261h 7mWatch on YouTube

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At a glance

WHAT IT’S REALLY ABOUT

Sequoia refocuses, Nvidia faces scrutiny, and AI markets test capital

  1. The episode breaks down Sequoia’s restructuring—leaving London, ending Scouts, merging early and growth, and winding down the Evergreen structure—through the lens of focus, LP incentives, and operational complexity.
  2. The panel debates the Nvidia situation, emphasizing it as a compliance and national-security investigation with potentially messy downstream scrutiny, even as some argue Jensen Huang is too important to lose.
  3. They discuss a sharp NASDAQ 100 selloff, with one view attributing it to positioning and forced de-risking rather than fundamentals, and another emphasizing market jitters about capital intensity and assumptions in AI.
  4. Anthropic’s IPO is framed as conservatively and strategically priced, with disagreement on whether it will pop or trade flat amid perceived market fatigue and concerns about long-term capital depth.
  5. They examine AI product economics (especially persistent agents), token pricing elasticity, and the accelerating security and M&A landscape, including heightened risk around AI API key theft and pressure on seat-based SaaS models.

IDEAS WORTH REMEMBERING

5 ideas

Sequoia’s Evergreen idea may have been right in theory, but too complex and LP-unfriendly in practice.

Rory O’Driscoll says the core insight behind Evergreen—“the real money is made after the IPO”—was intellectually correct, but the structure added complexity and forced LP behavior. He argues Sequoia likely faced timing issues (rolling it out into a drawdown), LP liquidity preferences, and misaligned incentives once partners had already “cleared carry.”

Sequoia’s restructuring signals focus—and reminds founders that VC institutions outlast individuals.

Harry Stebbings frames Sequoia’s London exit as a belief that Europe has great companies but can be covered from the U.S.; Jason Lemkin adds that many top European founders are frequently in the Bay Area anyway. Jason also draws a broader lesson: firms persist, but individual partners and structures can change quickly, so founders shouldn’t over-assume permanence in their VC relationships.

The Nvidia investigation is framed as compliance/security risk with uncertain consequences, not just scandal.

Rory O’Driscoll describes the Nvidia situation as personally messy and professionally serious, emphasizing that the investigation is about compliance and security, not the relationship itself, and that outcomes could become problematic depending on facts. Jason Lemkin argues Jensen “needs a pass” due to Nvidia’s importance, but Rory cautions this may not be easy given national-security scrutiny and potential follow-on investigations.

They disagree on what the NASDAQ drop “means,” but converge that demand and capital depth will decide the AI cycle.

Rory O’Driscoll rejects the idea that a single selloff indicates the “AI trade” cracking, arguing the key determinant is demand, visible in ARR at companies like OpenAI and Anthropic; he attributes the move more to leveraged positioning and forced de-risking. Jason Lemkin counters that markets are rational to be jittery given assumptions around capital, debt, and ongoing funding requirements.

Anthropic’s IPO is portrayed as strategically priced, but debate centers on whether investor fatigue limits upside.

Rory O’Driscoll praises Anthropic’s IPO approach: price conservatively, then potentially walk up, since “it is far better in an IPO to start low and go up.” Jason Lemkin predicts it may trade flat due to market fatigue, while Harry Stebbings relays an allocator’s concern about the “next 100 billion” of capital being a thin layer for continual funding needs.

WORDS WORTH SAVING

5 quotes

What, what the hell happened there? Why the hell are we winding down the Evergreen fund?

— Jason Lemkin

The institution may be durable, no particular partner may be durable.

— Jason Lemkin

I'm gonna say this again, and I'm gonna say it every week 'cause I-- The AI trade doesn't crack on the supply side. Doesn't crack.

— Rory O’Driscoll

Objectively speaking, he needs a pass, right?

— Jason Lemkin

Everyone's trying to steal API keys for inference, and f- they're all trying to steal Anthropic and OpenAI keys, and they have massive swarms of bots.

— Jason Lemkin

Read the available transcript
Sequoia restructuring: London, Scouts, team consolidationEvergreen fund incentives and LP liquidityFounders Fund concentration vs diversificationNvidia investigation and governance scrutinyNASDAQ 100 selloff and AI trade narrativesAnthropic IPO pricing strategy and market appetiteOpenAI revenue growth and enterprise mix shift (per Greg Brockman)

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SPEAKERS

  • Jason Lemkin

    guest

    Founder of SaaStr and a SaaS-focused investor known for scaling and advising B2B software companies.

  • Harry Stebbings

    host

    Founder and host of The Twenty Minute VC (20VC) podcast and a venture capital investor.

  • Rory O’Driscoll

    guest

    Venture capitalist and longtime software investor (known for work at Scale Venture Partners).

High quality AI-generated summary created from speaker-labeled transcript.

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