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Oxford Psychiatrist: The Fastest Way To Cure RSD! (New Research)

Dr Jessica Eccles PHD is an ADHD expert specialising in RSD. Oxford and Cambridge graduate in medicine, she’s here to share groundbreaking research shedding light on RSD Chapters: 00:00 Trailer 02:13 New RSD research 15:53 The link between RSD and masking 27:46 Beth’s RSD story 33:07 How RSD makes you vulnerable 34:50 RSD coping strategies 36:18 Tiimo advert 37:53 What causes an RSD trigger 48:15 How to measure RSD 54:00 Common medication for RSD related pain 58:47 Audience questions 01:07:54 A letter to my younger self Find Dr Jessica on Instagram 👉 https://www.instagram.com/drbendybrain/ Visit Dr Jessica’s Youtube 👉 https://www.youtube.com/@BendyBrainDrJessicaEccles ADHD Chatter LIVE show tickets 👉 https://www.aegpresents.co.uk/event/adhd-chatter/?cpch=AEGPRESUK_SOCIAL&cpcn=AEGPRESUK_ADHDChatter_London_SOCIAL_Artist_11032026_OGNC_&utm_source=ig&utm_medium=social&utm_content=link_in_bio Join the ADHD Chatter Patreon community 👉 https://www.patreon.com/cw/ADHDChatter Get 30% off an annual Tiimo subscription 👉 https://www.tiimoapp.com/offers/adhdchatter Buy Alex's book entitled 'Now It All Makes Sense' 👉 https://www.amazon.co.uk/Now-All-Makes-Sense-Diagnosis/dp/1399817817 Order Alex’s latest book about Rejection Sensitive Dysphoria 👉 https://linktr.ee/adhdchatter?utm_source=linktree_profile_share&ltsid=9ffd8709-06df-444c-9936-c136fbd14d6e Producer: Timon Woodward  Recorded by: Hamlin Studios Trailer editor: Ryan Faber DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website.

Dr. Jessica EcclesguestAlex Partridgehost
May 3, 20261h 8mWatch on YouTube ↗

At a glance

WHAT IT’S REALLY ABOUT

New research reframes RSD as embodied pain and uncertainty intolerance

  1. The guest explains that RSD is widely discussed but under-researched, and new qualitative findings suggest rejection sensitivity is an embodied, physical experience often described as gut-wrenching or chest-punch pain.
  2. Their recent work links rejection sensitivity with social withdrawal and masking, and they describe (unpublished) quantitative findings suggesting rejection sensitivity can relate to dissociation moderated by masking.
  3. The conversation frames RSD and “social pain” as overlapping with physical pain in the brain, with implications for why neurodivergent people may use substances or other predictable behaviors to dampen unbearable uncertainty.
  4. They explore how triggers can arise from ambiguous social cues (e.g., a boss requesting a chat) and how rumination and pattern-learning can condition people to avoid social situations, increasing loneliness.
  5. The episode proposes ways RSD could be objectively measured in future research (brain imaging plus physiological monitoring and rejection-induction paradigms) and ends with neurodiversity-affirming guidance focused on identifying one’s “spiky profile” of needs and strengths.

IDEAS WORTH REMEMBERING

5 ideas

RSD is real to sufferers but still scientifically under-defined.

Eccles emphasizes that despite the term’s popularity, rigorous research is limited; their paper adds evidence about lived experience but broader validation and standardized definitions remain needed.

Rejection sensitivity is often experienced as whole-body pain, not just “big feelings.”

Participants described visceral sensations (gut-wrenching, punch-in-chest, temperature changes), supporting a brain–body model where social threat is processed like physical threat.

Masking may reduce immediate fallout yet increase longer-term disconnection risks.

They report emerging data that rejection sensitivity relates to dissociative experiences, with masking altering this relationship—suggesting coping by “shutting off” can have mental health costs.

Ambiguity and uncertainty are potent RSD amplifiers.

Examples like “Can we chat Monday?” illustrate how unclear cues can trigger catastrophic narratives; adding context (e.g., an agenda) can materially reduce distress, especially at work.

RSD can drive avoidance, people-pleasing, and self-sabotage that narrows life options.

The discussion highlights missed opportunities, withdrawing from social/career risks, or deliberately handing work in late to soften potential rejection—strategies that protect short-term but constrain long-term.

WORDS WORTH SAVING

5 quotes

We really don't know a lot about RSD.

Dr. Jessica Eccles

Rejection sensitivity, the research that we did suggests that it is a whole-body thing.

Dr. Jessica Eccles

If you do that for so long, how do you know who you are?

Dr. Jessica Eccles

A lot of neurodivergent people find tolerating uncertainty absolutely painful.

Dr. Jessica Eccles

The body is a context setter for our emotions.

Dr. Jessica Eccles

RSD research gap and definitionsEmbodiment: social pain as physical painMasking, withdrawal, and dissociationUncertainty intolerance and catastrophizingTics/Tourette’s, echo phenomena, and emotional dysregulationTrauma, autonomic “hair-trigger” responses, interoception/alexithymiaMeasurement ideas: physiology, Cyberball, Trier Stress Test, interventions

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