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The Diary of a CEOThe Diary of a CEO

Jessie Inchauspé: How tiny food hacks flatten glucose spikes

Inchauspé says most people spike glucose daily, fueling cravings and aging: a savory breakfast and slower order of food at meals quietly flatten the curve.

Steven BartletthostJessie Inchauspéguest
Sep 19, 20241h 40mWatch on YouTube ↗

CHAPTERS

  1. 12:00 – 35:00

    Glucose 101: Why Spikes Quietly Damage Your Body

    Jessie explains what glucose is, which foods raise it, and why spikes matter even if you don’t have diabetes. She unpacks the three core processes behind spike damage: mitochondrial overload, internal ‘cooking’ (glycation), and insulin-driven fat storage and insulin resistance.

  2. 35:00 – 1:06:00

    Hidden Sugar, Misleading Health Halos, and Sweeteners

    The conversation turns to surprising spike-inducing foods and the myth of ‘good sugar.’ Jessie contrasts whole fruit with juices and smoothies, explains why modern fruit is unnaturally sweet, and evaluates different artificial and natural sweeteners.

  3. 1:06:00 – 1:26:00

    Hormones, Fertility, PCOS, Skin, and Aging

    Jessie connects glucose and insulin dynamics to visible aging, skin conditions, and reproductive health. She describes how insulin resistance underlies many PCOS cases and how stabilizing glucose can reverse symptoms and restore fertility in some women.

  4. 1:26:00 – 1:37:00

    The Four Core Glucose Hacks and 4‑Week Experiment

    Jessie lays out her four most impactful hacks—savory breakfast, daily vinegar, veggie starters, and post-meal movement—and describes results from a 2,700‑person global trial. Participants added these habits without cutting any specific foods.

  5. 1:37:00 – 2:03:00

    Glucose, Cravings, Discipline, Mood, and Relationships

    The discussion shifts to how glucose stability shapes behavior, habits, and relationships. Jessie explains how spikes hijack the brain’s craving circuitry, influence mood, and even correlate with marital irritation in a whimsical voodoo-doll study.

  6. 2:03:00 – 2:10:00

    Beyond the Core Four: Ten Glucose Hacks and Food Order

    Building on the core protocol, Jessie outlines all 10 hacks and emphasizes the power of food order and carb ‘clothing.’ She shows how traditional pairings (grapes and cheese, rice and beans) and simple sequencing drastically change glucose outcomes without changing menus.

  7. 2:10:00 – 2:42:00

    Kids, Parenting, and the Early Metabolic Environment

    Steven asks how parents should think about sugar for children. Jessie stresses that early high-glucose diets are already driving type 2 diabetes in kids and encourages parents to see sugary convenience foods as akin to cigarettes—something you can say no to.

  8. 2:42:00 – 3:07:00

    Vinegar, Visceral Fat, and the Anti-Spike Formula

    Jessie demonstrates the vinegar hack live and introduces her supplement ‘Anti-Spike Formula,’ based on lemon-derived eriocitrin and mulberry leaf extract. She explains how these ingredients naturally boost GLP‑1 and block a portion of glucose absorption.

  9. 3:07:00 – 3:36:00

    GLP‑1 Drugs, Food Systems, and The Sugar Economy

    The conversation zooms out to the societal level: GLP‑1 drugs like Ozempic, industry incentives, and the ‘sugar economy.’ Jessie and Steven discuss why our environment almost guarantees overconsumption and how this isn’t a cartoonish conspiracy so much as misaligned incentives.

  10. 3:36:00 – 4:14:00

    Glucose, Depression, Sleep, Coffee, and Menopause

    Jessie highlights emerging links between insulin resistance and depression, and how dinner spikes impair restorative sleep and drive morning hunger. They also discuss caffeine, individual sensitivity, and how menopause worsens glucose responses but can be partly mitigated with diet.

  11. 4:14:00

    Mindset, Motivation, and a Cab Driver’s Message

    In the closing section, Jessie reflects on burnout, public scrutiny, and purpose. She recounts a powerful moment when a London cab driver, unprompted, told her that whatever she was doing was important—an affirmation that helped her continue her work.

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