Dr. Tony Wyss-Coray on Huberman Lab: How blood resets aging

Parabiosis cut inflammation in aged mice via young blood factors; blood protein panels now assign organ age gaps that predict disease risk years before.

Dr. Tony Wyss-CorayguestAndrew Hubermanhost

Feb 23, 20261h 59mWatch on YouTube ↗

EPISODE INFO

Released: February 23, 2026
Duration: 1h 59m
Channel: Huberman Lab
Watch on YouTube: ▶ Open ↗

EPISODE DESCRIPTION

Dr. Tony Wyss-Coray, PhD, is a professor of neurology at Stanford School of Medicine who is discovering factors present in young blood and in exercised blood that can improve brain, heart and other organ health. We discuss how different organs age at different rates and how to accurately measure biological aging. We also discuss the specific proteins found in blood when we are young and that are increased by things such as exercise, sunlight exposure, short-term fasting, specific foods and social connection that can significantly increase vitality, restore youthful functioning of the brain and body and potentially increase lifespan. Show notes: https://go.hubermanlab.com/U67koOl Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman LMNT: https://drinklmnt.com/huberman ROKA: https://roka.com/huberman Function: https://functionhealth.com/huberman Huberman Lab Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab X: https://x.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter Dr. Tony Wyss-Coray Stanford cademic profile: https://med.stanford.edu/profiles/tony-wyss-coray Lab website: https://web.stanford.edu/group/twclab/cgi-bin Publications: https://scholar.google.com/citations?user=huboyZcAAAAJ&hl=en TED talk: https://www.ted.com/speakers/tony_wyss_coray X: https://x.com/wysscoray LinkedIn: https://www.linkedin.com/in/tony-wyss-coray-91592010 Timestamps 00:00:00 Tony Wyss-Coray 00:03:00 Young vs Old Animals, Age-Related Disease 00:06:35 Blood Biomarkers, Young vs Old Humans, Alzheimer's Disease 00:12:50 Sponsors: David & LMNT 00:15:28 'Young Blood' Factors, Rejuvenation, Stem Cells 00:20:15 Blood Banking; Dracula 00:23:10 Rates of Aging in Organs, Age Gap & Disease Risk; Risk Profiles & Therapies 00:33:02 NAD Levels & Aging, NMN Supplements 00:36:44 Vitality vs Longevity; Periods of Accelerated Aging 00:43:17 Sponsors: AG1 & Roka 00:45:22 Sunlight; Youthful Blood Factors, Exercise & Brain Function, Fasting 00:51:25 Exercise, Injury & Inflammation 00:56:18 Pro-health Factors, Klotho, GDF11, Stem Cell Injection Risk 01:02:35 Platelet-Rich Plasma (PRP); Exosomes 01:05:43 Smoking, EMFs, Plastics, Long-Term Accumulation, Fresh Foods, Organic Food 01:11:28 Sponsor: Function 01:13:16 Intermittent Fasting, Long-Term Fasting, Snacking 01:19:07 Sleep; Cerebrospinal Fluid (CSF) Factors & Cognitive Function 01:24:44 Exercise Type & Longevity; Exercise Enjoyment 01:32:02 Lifestyle Factors & Alzheimer's Risk; Cognitive Exercise; Chocolate 01:37:05 Alcohol & Social Connection; US vs European Food Culture 01:40:50 Deliberate Deep Breathing; Wearables, Sunlight & Artificial Light 01:49:13 Future Projects 01:56:40 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter #HubermanLab #Science Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

SPEAKERS

Dr. Tony Wyss-Coray
guest
Andrew Huberman
host

EPISODE SUMMARY

In this episode of Huberman Lab, featuring Dr. Tony Wyss-Coray and Andrew Huberman, Dr. Tony Wyss-Coray on Huberman Lab: How blood resets aging explores how young-blood factors, exercise signals, and biomarkers reshape aging science Dr. Tony Wyss-Coray explains research showing that circulating factors in young blood (and in exercised animals’ blood) can improve brain function in older mice, including reduced inflammation, stem-cell reactivation, and better memory.

RELATED EPISODES