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Joe Rogan Experience #1246 - Pot Debate - Alex Berenson & Dr. Michael Hart

Alex Berenson is a former reporter for The New York Times and the author of several thriller novels and a book on corporate financial filings. His new book "Tell Your Children: The Truth About Marijuana, Mental Illness, and Violence" is available now via Amazon. Dr. Michael Hart is the founder and medical director of Readytogo clinic, a medical cannabis clinic in London, Ontario, Canada.

Joe RoganhostDr. Michael HartguestAlex Berensonguest
Feb 13, 20192h 48mWatch on YouTube ↗

EVERY SPOKEN WORD

  1. 0:044:58

    Setting the stage: benefits, risks, and why this debate matters

    1. JR

      ... two, one, and we're live, ladies and gentlemen. Uh, or gentleman, you too.

    2. MH

      (laughs)

    3. JR

      Ladies and gentlemen listening, but you too, uh, unless you have some non-binary handle that you enjoy. It's, it's a new world. Uh-

    4. MH

      I don't. (laughs)

    5. JR

      Please, please introduce yourself.

    6. MH

      Sure. So, uh, I'm Dr. Mike Hart, originally from St. John's, Newfoundland. Uh, now I'm residing in London, Ontario, and I'm a family doctor. And I've been practicing cannabis medicine for just over five years.

    7. JR

      And you, sir?

    8. AB

      Uh, my name's Alex Berenson. I used to be a New York Times reporter. Uh, then I became a spy novelist. And most recently, I wrote the book Tell Your Children: The Truth About Marijuana, Mental Illness, and Violence, which came out last month and, uh, has not endeared me to the cannabis advocacy community, I'd say.

    9. JR

      Have they, uh, attacked you mercilessly for this book?

    10. AB

      Yes, they have.

    11. JR

      Yes.

    12. AB

      And, and that's, and that's okay. Um, uh, I've also heard from a lot of parents, uh, you know, some users, but parents who've told me, uh, that the book really encapsulates their, their family's problems-

    13. JR

      Hmm.

    14. AB

      ... in the last couple years.

    15. JR

      Um, I suspect m- my, my real thoughts here, before we even get started, is that we're gonna find that the truth is somewhere in the middle here. Um, I don't think marijuana is 100% safe, honestly, for everybody. I really don't. I know too many people that have had experiences where they took too much, particularly edibles, and, uh, I don't, I don't wanna say I know anybody who had psychotic breaks, but I know some people that freaked out for weeks, you know. In fact, uh, we just had a, uh, a comedian here from Brazil, um, a couple days ago, Rafi Bastos, who said he took a couple of hits of a vape pen and was high for 14 days.

    16. MH

      (laughs)

    17. JR

      Went to a psychiatrist and, and he's a big guy. He's like 6 foot 5, 6'6", you know, and, you know, they told him to keep taking it 'cause, you know, he's like, "You're so big. Just keep smoking." And so he, he doesn't smoke, so he just kept hitting his vape pen, and he said, "I was high for fucking two weeks."

    18. MH

      Yeah, so you need to do it properly, right?

    19. JR

      Yes.

    20. MH

      It needs to be held to the same standard as any other medicine.

    21. JR

      Yeah.

    22. MH

      So we need to identify that there's risks and there's benefits to it.

    23. JR

      Yes.

    24. MH

      Right? And, and some people are definitely, you know, going to be more susceptible to those risks.

    25. JR

      Yeah.

    26. MH

      And we need to kinda, you know, tease out those people and make sure that those people, you know, don't, uh, put themselves at risk.

    27. JR

      Yeah, I, I think so as well. And this is one of the reasons why I wanna state this, 'cause I'm a well-known marijuana advocate, but I, I do believe, I believe absolutely there are great benefits to it. I think there's great benefits in terms of, uh, relieving pressure, ocular pressure for people that have glaucoma, people with AIDS who are on medication, people with cancer that are going through chemotherapy find great benefit in terms of helping them. And then there's also some people with autism, I know people that, who, their children have autism, and they give them small amounts of edible marijuana and it stops seizures. It's incredibly beneficial in the form of CBD for a lot of different ailments. But I think with all things, and this is a, a stance that I've kind of, like, really come to accept over the last few years, with all things that affect the mind, they affect everyone slightly differently.

    28. MH

      Absolutely. Yeah. Alex, you wanted to say something there?

    29. AB

      Um, no, no. Well, first of all, I, I suspect... You know, there are people who said, "Don't go on with Joe. He's just gonna, you know, he's gonna try to eat you alive, and, and especially there'll be, it'll be two on one." I told them the truth. First of all, I, I'll go on with anybody, and I am glad you had me on or you're having me on because, uh, you know, Bill Maher, he won't have me on. He's afraid to talk to me about this.

    30. JR

      Why?

  2. 4:588:44

    Is cannabis safer than alcohol? Deaths, attribution, and “associated” harms

    1. MH

      I don't... I really strongly disagree with that. And I mean, you just have to look at the death rate, right? Uh, you know, more people die from alcohol than, you know, almost all drugs combined. But when we're looking at cannabis, there's zero deaths attributed to the use of cannabis itself. Sure, you could say, you know, someone could use cannabis and, and jump off a cliff or something like that, but we're talking about the lethal dose. You cannot die from cannabis. And just based upon that alone, it makes it much, much safer than alcohol. So in addition-

    2. AB

      Yeah, how could-

    3. JR

      How could you say that if, if that is the case?

    4. AB

      So, okay, so that's a really good question. Uh, the normal number that's used for US deaths from alcohol is about 90,000. Now, about-30 to 40,000 of, of those deaths are deaths from the physical effects of alcohol, right? Essentially liver damage.

    5. MH

      Mm-hmm.

    6. AB

      Either chronic liver damage, you get cirrhosis, you die. In some cases, you can drink so much that you kill yourself in a night. Uh, so that's about 30 to 40,000 deaths. The other deaths are generally associated with alcohol, meaning somebody, uh, drank-

    7. MH

      Violence.

    8. AB

      Exactly. Violence, suicide, car accidents and the, all those numbers are basically based on studies from the '90s and before, where, you know, people looked at traffic accidents and there were a certain number of those accidents where people had a blood alcohol content of higher than 0.1. They said, "Okay, that's an alcohol associated death." That's a fine way to count as far as I'm concerned. Nobody has ever done that count for cannabis, and I can tell you based on the, on the tox screens that I've seen from Colorado, where people, uh, had cannabis in their blood and committed suicide, people had cannabis in their, or I should say THC in their blood and, uh, and got into fatal confrontations with police officers, if, if, if and when we do this number for cannabis, which we need to do as soon as possible, the number's (laughs) gonna be a lot higher than zero. I suspect it will be in the 10 to 20,000 range. We won't know till we actually do it.

    9. MH

      Okay, but let's, let's eliminate ... Let's go even over the alcohol. Let's eliminate all things like violence and let's eliminate suicide, and let's assume those people would've committed violence and committed suicide without it. You're still looking at a giant number of people who drink themselves to death.

    10. AB

      Yes. (laughs)

    11. MH

      Thousands and thousands and thousands of people every year versus zero with marijuana. And you're aware, I'm sure, that correlation does not equal causation, and that especially in a place like Colorado where you're dealing with cannabis, something that stays in the system for many, many weeks, if you're testing people and they test positive for marijuana and they wind up committing suicide or they wind up committing violence, they don't ne- even necessarily have to have been under the influence of it.

    12. AB

      Well, y- as you know, there's ... Wh- when you test the blood, you can test the, both the active metabolite and the inactive metabolite of THC.

    13. MH

      Right.

    14. AB

      So, so the test, when you do a blood test on somebody who's, you know, who's committed suicide, it's sophisticated enough to tease that out.

    15. MH

      Mm-hmm.

    16. AB

      Um, so there's a lot of people who have the active metabolite in their blood. Um, I, I agree. Alcohol is a physically toxic substance. Cannabis is a neurotoxin for a lot of people.

    17. MH

      But in addition to, you know, the deaths, there's also just the morbidity, uh, that, that's associated with alcohol. I mean, it ruins people's lives. It ruins marriages. Uh, it leads to weight gain. It leads to a lot of metabolic disturbances, right? So ... Well, you could ... I think you could say that for some people with marijuana too. I think you could say some people, especially weight gain, that some people smoke a lot of pot and they get lazy and they start eating Cheetos all day.

    18. AB

      (laughs)

    19. MH

      And, and you can also say that e- with some people, you know, the wake and bakers that, you know, seem to be wasting their lives away, and that's like the stereotypical negative con- ... You know, the ... When you, when you're talking about a negative description of a marijuana user, it's the wake and baker, right? The person who's high all the time.

    20. AB

      Mm-hmm.

    21. MH

      You could absolutely say that could rel- ruin relationships. You could absolutely say that would ruin your job.

    22. AB

      Uh-

    23. MH

      Eh, you could, but again too, you know, we're using the term marijuana-

    24. AB

      Mm-hmm.

  3. 8:4410:23

    THC vs CBD: why cannabis isn’t one thing (munchies, receptors, and THCV)

    1. MH

      And really we should be using THC or high THC when we're, when we're saying that.

    2. AB

      Okay.

    3. MH

      Because, you know, people who use, uh, high CBD every day, as, as we know, or most people that listen to this-

    4. AB

      Sure.

    5. MH

      ... probably know that CBD is non-psychoactive.

    6. AB

      Sure. Yeah.

    7. MH

      It does not get you high. So ... Super beneficial. Yes.

    8. AB

      You know, that can be-

    9. MH

      Yeah.

    10. AB

      ... yeah, extremely beneficial for, you know, a variety of different disorders that people have.

    11. MH

      Yeah. So, you know, we n- really need to be careful about using cannabis versus using, you know, THC because it's really- Well, I think- ... th- the THC that can do that. And to your point- Yeah. ... you know, but, you know, you say like, yeah, THC can cause the munchies, and of course that's, you know, not good for someone who, uh, doesn't wanna gain weight. And just, you know, so people know, the, the way that it does, uh, do that is when THC attaches to the CB1 receptor, you get an increase in a hormone called ghrelin. And ghrelin, uh, can actually induce hunger, and that's why people get, get, uh, the munchies. But, you know, that is not necessarily a bad thing if you're someone who has cancer-

    12. AB

      Sure.

    13. MH

      ... or if you're someone, you know, who, who's wasting away from, from, from a terrible illness. You know, so sometimes, you know, having, um, having the munchies is, is definitely a good thing. Um, and I know, you know, a lot of people, uh, have, have said to me, you know, "It's not available, so you should probably, you know, not talk about it as much," but there is another cannabinoid called THCV. So, you know, there's, there's over 100 cannabinoids in cannabis. THC and CBD are only two of them. You know, those are the main ones that people know about. So THCV has been shown to actually reduce appetite. So if we can get that out there in the market, you know, like we have with, with CBD, then we can almost, you know, eliminate or, or potentially, you know, substantially reduce the problem that people have with, with, uh, with THC by using it, uh, with, uh, THCV.

  4. 10:2313:48

    Medical vs recreational reality: who seeks cannabis care and what ‘medicine’ means

    1. AB

      Do- Dr. Hart, I have a question for you.

    2. MH

      Sure.

    3. AB

      When people come into your practice, do they, do they want high CBD products or do they wanna get intoxicated? And y-

    4. MH

      No, absolutely. Well, in Canada, it's fully legal.

    5. AB

      Ab- absolutely.

    6. MH

      Sure. Of course.

    7. AB

      Yeah.

    8. MH

      So it's like- Yeah. ... if they ... They don't need to go to him to get intoxicated.

    9. AB

      R- right. So people ... So you're seeing a population that is genuinely interested in the health benefits here.

    10. MH

      Absolutely. Because, I mean, if ... And, I mean, I'm glad that, that, uh, that it's legalized in Canada because it does make my job a little bit easier because be a ... Like basically everyone who's coming to me now, I know that they wanna use it medically, because if they want to use it recreationally, I mean, they just go to the store, right?

    11. AB

      Right.

    12. MH

      'Cause it's kind of a pain to, you know, get in to see me, come in and have the discussion, all that type of stuff. So, you know, the people who see me now, um, you know, they're all using it medically. Um, and then, you know, to, to answer, uh, your question though, Alex, almost all my patients, as soon as they come in, they say, "I don't wanna get high. I don't wanna get high." Like, that's almost what everyone says. So, you know, I think the word is out there that, uh, you know, CBD is non-psychoactive and it doesn't get you high, and I think that a lot of people are really interested in that compound. And, you know, if, if, if the people didn't have the, the, the success that they've had over the past few years, you know, it wouldn't be as popular as it is. So, you know, I think that, um, you know, we do need to look at the scientific evidence, but we do need to listen to others. And the anecdotal evidence is, you know, something that, that w- that we should consider because it is so strong. Alex, let me ask you this. Why don't you consider it medicine when it has proven medical benefits?

    13. AB

      Well, it obviously can be medicine for these narrow things that the FDA has approved it for, but as you know-

    14. MH

      (clears throat)

    15. AB

      ... I'm sure, a-... when people talk about it as medicine, when the, the, the, the, the ballot initiatives that have gotten it approved as medicine have really essentially deceived voters about the process, right? So you go to a, y- you go to a pot doctor, you get an authorization. That authorization essentially enables you to buy as much cannabis as you want for the next year. Most of the time, in reality, these doctors are not giving you a real medical examination. They're saying to you, "Hey, do you have pain? Do you have anxiety? Here's your authorization."

    16. MH

      Mm-hmm.

    17. AB

      It t-

    18. MH

      I don't think you should speak for every single doctor, though, okay?

    19. AB

      No, no, no. No, no, not every... No.

    20. MH

      Because we don't do that, uh, at my clinic, and I know that, you know, a lot of the clinics in Canada anyway, uh, we definitely do not do that, and, um, you know, we, we, we provide a lot of education at my clinic, and there's other clinics in Canada that also provide a lot of education.

    21. AB

      Sure. And, and, and I, and I imagine there's a spectrum. But in the US, this was a se- ... And, and I spoke to advocates for my book. I spoke to Rob Campia, who, you know, who ran the Marijuana Policy Project for a long time-

    22. MH

      Mm-hmm.

    23. AB

      ... um, for the book, and he, and he acknowledged, you know, the advocates knew that this was a backdoor route to legalization in the US.

    24. JR

      Yeah, I, I used to joke around about it.

    25. AB

      Yeah.

    26. JR

      That my doctor said, uh, "Why do you eat pot?" I said, "I get headaches." He said, "When do you get headaches?" I said, "Whenever I think about the fact that pot's illegal."

    27. AB

      (laughs)

    28. MH

      (laughs)

    29. JR

      So he wrote me a prescription.

    30. AB

      I mean, let's be honest about it.

  5. 13:4818:12

    Evidence standards clash: anecdotes vs randomized trials (and what THC actually treats)

    1. JR

      Epilepsy, autism, those are two huge things that happen with children that they've been shown to severely mitigate with, with edible marijuana.

    2. AB

      So I have to push back on you a little bit. Uh, CBD has been shown to reduce seizures in, in children with epilepsy. It's, it's FDA approved for that use.

    3. JR

      Okay, this may be anecdotal, but I have a good friend who has a child who he uses it on, and he's showed it's, it, I mean, it's been a l- a game changer.

    4. AB

      Right, so there's-

    5. MH

      Yeah, I mean, I... Well, just let me interrupt for a sec. So like I had, uh, a patient four or five years ago, and, uh, she was 20 years old. She couldn't drive a car because she had seizures, right? So you can imagine being 20 years old, not being able to drive a car, all your friends are driving around. So she uses a little bit of CBD, not even every day. She's never had a seizure since.

    6. AB

      Okay, but I think he's-

    7. MH

      And now she's able to drive her car.

    8. JR

      But, but this is, we're talking about CBD. He's talking about THC.

    9. MH

      So ...

    10. JR

      And ...

    11. AB

      So you're talking about, you're talking about a case, okay?

    12. JR

      Yeah.

    13. AB

      And, and I'm not saying that your friend's situation didn't happen. I'm not saying it's not real. What I'm saying is that the reason we have clinical trials is because science ... the way you know whether a medicine works or not, whether a chemical compound works, whatever that compound is, the best way to know is you give it to two groups of ... or you give, you give the real medicine to one group of people and you give a placebo to the other group. And you see the changes in those two groups over time, and you find out whether or not your theory about whether this works on a population level basis is real or not. That's how, that is at the core of medical science, and we've basically thrown that rule out for THC.

    14. JR

      Well, that's not entirely correct. You do know that there was, were studies that were run during the Nixon administration that showed the efficacy of marijuana and the safety of it, and those were all squashed. And you also, I'm sure you, you know like when we're talking about marijuana, you're talking about something that's federally illegal.

    15. AB

      Yes, of course.

    16. JR

      It's not something that's eagle- that's easy to run these FDA studies on.

    17. AB

      Yes. And I do think, and I say at the end of the book, I think we should drop that. I think anybody who's got a legitimate interest in researching either THC or cannabis or any of the compounds for a, for a medical condition, let them run phase one, phase two, phase three trials. Let's see if this, if this c- if this plant is good for these things.

    18. JR

      I think that's a great idea. But still, why are you saying that you don't think it is medicine when all these people find benefit in it?

    19. AB

      So, so ...

    20. JR

      Do you think they're getting it from just the CBD, the minimal amount of CBD in, in marijuana?

    21. AB

      No, I think that, again, there, there's been a lot of research done on THC and cannabis to see whether or not those, uh, whether THC as a compound and whether smoked cannabis can treat these conditions. And for the most part, the studies have been negative. The, again, there's-

    22. JR

      Negative in what way?

    23. AB

      Meaning they haven't shown any actual, uh, like, uh-

    24. JR

      Can you cite, cite these studies?

    25. AB

      Uh, they're ... I mention them in my book.

    26. JR

      Okay. Well, what, what were the conclusions of these studies when you're saying that they're not positive?

    27. AB

      That they, again, that they didn't work, that the drug did not work.

    28. JR

      Didn't work on what?

    29. AB

      On cancer, on Alzheimer's disease, on irritable bowel syndrome, on all kinds of-

    30. MH

      So, Alex, I mean, you know, you're throwing a, a few different things out there, and, you know, I appreciate the fact that we can't be going around, you know, saying things like, you know, "Cannabis cures cancer," right?

  6. 18:1227:35

    PTSD and the endocannabinoid system: Hart’s clinician argument for THC/CBD

    1. MH

      So, you know, it's, it's definitely a, a really good, um, you know, medicine for, you know, a lot of different things. And, and when we're talking about THC, you know, I, uh, I said earlier, of course, you know, we need to be careful about, about THC, but it definitely is still a medicine. And, you know, to your point with regards to, um, you know, it not being a medicine, say, for something like PTSD, you know, I come from it from a clinician's point of view, so I'm not a researcher. So I need to make sure that my patients are getting better. It's very frustrating for me just to say to someone, "Oh, there's nothing I can do for you. There's nothing I can do for you," you know? So ... And I understand that, you know, doing something sometimes, uh, is not going to be beneficial just because you're doing something. You have to do something that actually works. But, you know, we do have epidemiological studies and we have, uh, other studies that have shown that, um, you know, when, when patients are given, uh, cannabis, it can reduce their symptoms of PTSD. There's also another study. You know, I don't use this drug too often, call it, called Nabilone. So Nabilone is just pure THC. Nabilone was shown to reduce nightmares in people who have PTSD. So, you know, it's just saying just ... So just because THC is psychoactive doesn't mean that it's not a medicine. And just to keep on the topic of, of PTSD, um, in addition to that, we've identified mechanisms of action. Um, I know, I know there's one study, uh, I think Matt Hill was on the, uh ... was, was one of the authors of that study, and he noted that in people who have PTSD, there is an over 50% decrease in, uh, in levels of anandamide. So anandamide-

    2. AB

      Which is the naturally occurring-

    3. MH

      Yes.

    4. AB

      ... cannabinoid in your brain.

    5. MH

      Which is, which is, which is a naturally occurring endocannabinoid. Correct. Um, so you can get that through, through exercise, which is one excellent way to do it. You know, and that's part of the, uh, the high that y- that you get when, after you exercise. But the other way that you can get it is by using cannabis. So when, when THC attaches to those CB1 receptors, you can get a release of anandamide, and, uh, cannabidiol can actually increase anandamide, um, un- un- by another mechanism of action, uh, as well. So, you know, there's, there's different ways where we can, you know, raise a level of, of deficiency. So, you know, to me, as, as a clinician, you know, if I have someone who is not doing very well, you know, they've been on a bunch of different medications, I've identified that, you know, they have PTSD, we have a mechanisms of action, we have studies. And then again too, you know, don't discount my clinical experience, right? I've been, uh, working for over five years, you know, uh, just with, uh, just with cannabis. I mean, I do other medicines. Uh, I u- prescribe other medicines as well, but I've been doing cannabis medicine for, for over five years and, you know, there's a lot that, that I've learned, right? So as much as I've learned, you know, through reading studies, um, and, and through going to conferences and things like that, you know, for sure the, the, the best resource as a clinician is, is to learn from your patients and, and to hear what your patients tell me. And, you know, the, the things that my patients tell me is that THC is really effective for their sleep at night, and a lot of my patients, especially my veteran patients, have done really, really well w- with that. And just, just one further point too, you know, there was ... I know it was, it was in 2015 I believe it was, there was a meta-analysis done, I can pull it up if, if we need to, that indicated that, um, you know, a lot of medicines that are being used now for PTSD are just simply ineffective. And the other thing too is that there's never been a medicine made specifically for PTSD. So, all the medicines that people are using are for anxiety or they're for depression or they're for insomnia or they're f- or they're for something else, you know? But when we look at, uh, like, like a study that says people with PTSD have a lower level of anandamide, and then if you can increase that l- level of anandamide, you know, that's a good way to treat someone. It doesn't matter whether it's a vitamin, whether it's a hormone. As long as you are correcting a, a, a deficiency, you're generally gonna get excellent clinical results.

    6. AB

      So, so let me, let me sort of try to frame this a different way. Um, alcohol reduces blood pressure. Okay? Alcohol in s- you know, generally tends to reduce, uh, cardiovascular events for people. Um, and during Prohibition, you could actually get a doctor's note for alcohol as a medicine, but alcohol is not a medicine, okay? It's a recreational intoxicant. It has some positive biological qualities and some negative biological qualities, and, uh, you know, there was an argument I think in 10 to 20 years ago, should we recommend that people y- drink moderately, one to two drinks a day? And I think for the most part, uh, th- the medical profession has calmed down on this by saying, "Let's not do that. There's too many non-cardiac, uh, negative side effects with alcohol."

    7. MH

      Just on that note though, Alex, in Canada right now I know the safe alcohol drinking guidelines are 14 drinks a week for men-

    8. AB

      Right, so two, two dr-

    9. MH

      ... and nine drinks a week for, for women.

    10. AB

      Right.

    11. MH

      So-

    12. AB

      So you're saying, so, so you're saying-

    13. MH

      You know, basically it's two, two a day for men, one and a half for women, so-

    14. AB

      Right. So, so you're saying okay, like, there's we don't see huge negative consequences at that level. Okay. That's ...... that's fine. Like, that's a totally reasonable way to think about alcohol. But what we're not saying to people is, this is a medicine, and I think that's where the confusion around, uh, uh, really around high-THC cannabis lies. And, uh, and again, I don't mean to say that your friend's child is not benefiting. I, uh, if you say, uh, he or she's benefiting, I believe you. What I'm saying is that that's not good enough for science. We need randomized controlled trials. And when those trials have been done, and a lot of them have been done, Joe, a lot of them have been done, they've almost unequivocally shown that cannabis doesn't work as a medicine. The only actual place where, beyond these sort of very limited conditions like, uh, chemotherapy associated nausea, which obviously is terrible for people who have it, but isn't, you know, isn't that common fortunately, um, cannabis has been shown to work as a pain reliever, right? Probably for the same reasons that alcohol works as a pain reliever. It sort of dulls your awareness of your pain. But even in that study, or in those, even in those studies, they're mostly done against placebo, not against opioids or against NSAIDs like ibuprofen. And there was a very big study for cannabis, uh, use in chronic pain over a multi-year period, uh, in Australia that came out last year that showed that people who used cannabis had a, uh, had more pain and used more opiates at the end of four years than people who didn't. So that, so I, I, we're almost arguing about what medicine is.

    15. JR

      Mm-hmm.

    16. MH

      Yeah, that study though had a lot of flaws in it. And the other thing is that you need to look at someone who is already using cannabis versus someone who is just using opioids. So if someone is just using opioids and they wanna come off cannabis, um, you know, there's multi-

    17. AB

      Come off opiates?

    18. MH

      Oh, sorry, sorry. Come off of, of opiates with cannabis. You know, multiple studies have shown that, that that can be, uh, effective. And that's not was, what was done in the Australian study that, that you're referring to.

    19. AB

      Right, it's a more naturalistic, uh, approach.

    20. JR

      Right.

    21. MH

      And, and also too, you know, they, they didn't have access to medical marijuana during that whole, during that whole time.

    22. AB

      Right, so people were getting it actually-

    23. MH

      Tho- those are all self-reported.

    24. AB

      Right.

    25. MH

      And they were getting it from, you know, recreational sources.

    26. AB

      Sure.

    27. MH

      They weren't getting it from... That's a big, that's a big distinction though, Alex.

    28. AB

      Yeah.

    29. MH

      Like, they weren't getting it from a doctor who prescribed it to them. They were, they were, this was a self-reported study and people were getting cannabis that, you know, they didn't really know what they were getting. It wasn't, uh, they weren't given any information from a doctor. And that's why it's a medicine, Alex.

    30. AB

      Right.

  7. 27:3529:46

    Accusations of selective citation: the National Academies report and ‘not balanced’ writing

    1. MH

      Yeah. And, and we need to be, you know, careful about that, right? And, and Alex, you know, you know, one thing that, that was mentioned in your book, um, you know, was that, you know, you, you ofte- you often cited the, uh, National Academies of Science and Engineering, right? But, you know, Zeva Cooper, you know, she's a member of that committee.

    2. AB

      Sure.

    3. MH

      I mean, she put out on, on her Twitter, I mean, you can go to it. It's from January 9th, uh, of, of 2019. She says, "In response in the recent New York Times editorial on cannabis, and as a committee member-"

    4. AB

      Which ca- but that, which by the way, that came out something that I wrote down and put in the book.

    5. MH

      Hang on, let me finish, Alex. Let me finish. Let me finish.

    6. AB

      No, no, I'm just trying to give people context of where it came from.

    7. MH

      Right. But this is, um, someone you cited.

    8. AB

      Yeah. Uh, no, I didn't cite her. I cited the report.

    9. MH

      Okay, you cited, you cited the, the report.

    10. AB

      Yes. Yes.

    11. MH

      And she's a member of that, of that, okay?

    12. AB

      Yes.

    13. MH

      So she said, "In response to the recent New York Times editorial on cannabis as a committee member on NASM," which is that committee, "and cannabinoids report, we did not conclude that cannabis causes schizophrenia." Then the Drug Alliance Policy also said, "The report did not reach that conclusion." So, you know, those are pretty two authoritative, uh, you know, sources that, that are saying that, you know, in your book you didn't cite the research properly, right? And then also they're saying that you left lot out, right? They said that they have found an association between marijuana use and improved cognitive outcomes in individuals with psychotic disorders. That's straight from the same report. And, you know, you failed to mention that, right? So I think that, you know, when we're writing books or when we're giving out information, you know, you want to do it from a balanced approach and you don't want to just-... select, you know, the small amount of, of material that's just gonna support your study. You know, we wanna be truthful here. You know, Joe's show has always been ver- very truthful. I mean, Joe said right at, right at the beginning he doesn't think that, uh, that, that cannabis i- is perfect for everyone, and I don't think that either. And in Canada, you know, we have really strict guidelines to follow. Um, you know, basically no one prescribes THC to anyone under the age of o- of 25, and, you know, all the conferences and stuff that I go to, you know, we don't really have too many discussions about that. Like, the doctors don't really have many, you know, m- much of a backlash about that. Um, so-

  8. 29:4643:41

    Schizophrenia rates, data quality, and what we can’t measure in the U.S.

    1. JR

      Wh- why is the distinction the age of 25? Why they decide that age?

    2. MH

      So 25 basically is when your, your brain-

    3. JR

      Frontal lobe.

    4. MH

      ... yeah, is f- is, is, is fully developed. And when you do look, um, at the studies that do show, you know, an association between, between cannabis and, and psychosis, it's almost all in adolescence. You know, I think that Alex only has one study, um, in, in his, in his book that shows an extremely weak correlation between, um, an adult using cannabis and then developing any type of, of mental illness later. So, you know, 25, um, is, is a, is a good age, but it's definitely a, you know, kind of a, a conservative-ish, -ish age. But, you know, it's, it's something that, that we follow, and I think that, you know, we've done well with that in Canada.

    5. JR

      So, Alex, why did you leave those conclusions outta your book?

    6. AB

      So I wi- I wi- I need to push back here.

    7. JR

      Okay.

    8. AB

      Um, so the National Academy of Medicine, uh, report, uh, was, uh, drawn up by a committee of 16 researchers. Uh, Ziva Cooper is the one who's publicly said, "The report said this, uh, but I think that we should've, uh, emphasized that it also said this," okay? What I, what I wrote in that New York Times op-ed, uh, what I wrote in the book, is the plain language of the report, and the plain language is this: Cannabis use is associated with a risk of developing schizophrenia and other psychoses. The higher the use, the greater the risk. I may have a word or two wrong in that 'cause I'm doing it from memory, but that's what it said. And by the way, the committee was very clear. They separated, uh, depression. They said, "There, we don't see as nearly as high risk for depression as psychosis," uh, even though, by the way, today, just today, uh, JAMA Psychiatry, the Journal of the American Medical Association Psychiatry, uh, put out a meta-analysis s- showing that cannabis is associated with depression, uh, and suicidal thinking, uh, and actually suicide attempts at a three-and-a-half to one rate. This l- this literally was released today. Um, but to, but to go back, Ziva is one of 16 members of that committee. So if you're gonna talk... If you're gonna say that I misquoted the report, which I didn't, I quoted it entirely accurately, you need to say, "Well, why aren't the other 15 members of that committee saying that I misquoted?" Why is one person who works for the Cannabis Research Initiative at UCLA, which takes money from cannabis investors and users, she's the one who said that I misquoted it. Maybe she... M- Maybe we should ask why the other members of the committee are not speaking out against my book.

    9. MH

      Well, I think that she was just one of the 16 members that, that came out, but, you know, you can't really expect, uh, all the other members to, to potentially, you know, come out with that as well.

    10. AB

      W- Why not? Why not?

    11. MH

      Well, some people will, and s- and-

    12. AB

      If I, if I did something wrong, if I misquoted them.

    13. MH

      Well, some people will and some people won't. You know, some people have, you know, the personality. Some people have the platform, like, you know, Ziva has a bunch of followers on, on her Twitter. People know who she is. You know, a lot of people who do research actually are not into social media at all. Like, I don't think you were at all before you, you had your book, were you?

    14. AB

      Uh, yeah. I mean, or I was a novelist-

    15. MH

      Right?

    16. AB

      ... so I was promoting my book, but sure.

    17. MH

      Okay. Yeah, so, so you weren't into social media at all. So, you know, I don't think that most people on that committee are in- are into social media. You know, Ziva just, just happens to be, and, you know, I even spoke to Ziva, uh, on the phone about this, and, you know, and, and, and she said that, "Yeah, you know, I, I don't..." uh, that she agrees with everything that was in the report, but she doesn't agree with your conclusions. And to go back to what-

    18. AB

      My conclusions are quoted from the report.

    19. MH

      But you're only quoting... They're... But you're only quoting the parts that, that cite, or, or sorry, that back your, uh, y- your opinions. You're not quoting the entire part. Like, you left... Like, why did you leave out the part that said they have found an association between marijuana use and improved cognitive outcomes in individuals with psychotic disorders, right? So you're leaving out that part, so why'd you leave that part out?

    20. AB

      If, if you, if you can-

    21. JR

      Why did you leave out that part?

    22. AB

      If you can find me a psychiatrist who thinks that it's a good idea for somebody with an active psychotic disorder-

    23. MH

      Okay, but why did you leave out that part?

    24. JR

      But why did you leave out that part?

    25. AB

      Well, my book presents... Uh, it makes a case, right? It makes a case that this is a big issue that we have not heard about at all, and the reasons that we haven't heard about it have a lot to do with the advocacy community and the way they've presented this data for 25 years. I wrote a book that is trying to break through a lot of noise.

    26. JR

      So, but, still, like, to, to get a balanced approach, did you decide that you were only going to s-

    27. AB

      I, I say, I say in the introduction-

    28. JR

      ... that you were only going to write about things that confirm your, the belief that you held when you were writing this, and what you were trying to push in the title of the book and in, in the conclusion of the book?

    29. AB

      I think that's a really great question. I say in the introduction of the book this book is not balanced.

    30. JR

      Okay.

  9. 43:411:18:04

    Social media vs cannabis as drivers of youth distress: suicide stats and interpretation fights

    1. JR

      Can I-

    2. AB

      And it's, uh-

    3. JR

      Can I stop you for a second there? Because there's other factors.

    4. AB

      Oh, sure.

    5. JR

      And one of the big one is Yuval Noah Harari has a great book, uh, 21 Lessons for the 21st Century.

    6. AB

      Yeah, I wro- I read that. It's a nice book, yeah.

    7. JR

      It's great. And, uh, one of the things they talk about is the onset of social media. Uh, Jonathan Haidt talked about that as well.

    8. AB

      Yeah.

    9. JR

      And, uh, that the onset of social media, it was actually more Haidt than, uh, Y- Yuval N- Harari. But the, uh, Jonathan Haidt talks about it with young people.

    10. AB

      Yeah, I think it's a huge part of it.

    11. JR

      I think it's the cotton ball of the American mind, yeah. I think that social media and the pressures of social media have led an incredible amount of young people to, uh, serious mental distress and, you know, serious anxiety, serious depression, and suicide amongst young girls has increased some 50% according to Haidt, um, o- over the period of 2007 to, I think, 2000 and whenever his book was written. Uh, and I think they're directly correlating that to the pressures of social media and to, you know, anonymous online bullying and all these different factors that are affecting kids.

    12. MH

      Yeah.

    13. JR

      So I think that, uh, that could be considered a, a far more significant new, uh, form of, of, of distress to children and y- and young people than even marijuana.

    14. MH

      I think it does it twofold, because I think that, you know, what makes people really depressed, maybe more so than, than anxious, but definitely both, is that when you compare yourself to someone else.

    15. AB

      Yes.

    16. MH

      And, you know, people, you know, obviously th- we've done that, you know, all, all humans have done that, you know, since th- since history began. But now everything is online. You can compare your life to everyone and people are doing it all the time. And even worse than that, and, you know, we should talk about this too, is that the income gap is getting, is getting wider. So it's like people's lives, not only are they getting, you know, better than, than, than other people's lives, but it's, but it now it's on, it's on display so everyone can see it. Whereas before, you know, maybe you wouldn't, you wouldn't have seen it because it wasn't on social media.

    17. JR

      Mm-hmm.

    18. MH

      But now it's, it's on social media. So you have this huge income gap that just keeps getting bigger and bigger and bigger. And then you have people going, going on social media and they're comparing themselves. And you're absolutely right, especially in that, in that age population.

    19. AB

      Right.

    20. MH

      I mean, people under, under the age of 30, you know, they're definitely, um, you know, they're, they're being bullied online. Like I see it every day in my office. Like literally every day people are being bullied online. And that's, you know, something that I never had, you know, to deal with, uh, growing up.

    21. JR

      Yeah.

    22. MH

      Um, and, you know, a lot of kids do have, do have to, to, to deal with that. Just one more note too-

    23. AB

      Oh, sure.

    24. MH

      ... uh, on the, uh, since Colorado has, has, has legalized cannabis, this is important for, for this, uh, this, this subject and this topic. Um, they've actually seen marijuana rates decrease. So it's important for people to know that, you know, just be-

    25. AB

      No, not, no, no, no, no. They haven't seen-

    26. MH

      Yeah, I can, I can pull up the study.

    27. AB

      Did- are you talking about teen, teen use or overall use?

    28. MH

      Oh, I-

    29. AB

      Overall use has gone up.

    30. JR

      Teen use is flat, overall use is up.

Episode duration: 2:48:30

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