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Lewis HowesREVERSE AGING: What To Eat & When To Eat For LONGEVITY | Dr. Mark Hyman & Lewis Howes
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110 min read · 22,168 words- 0:00 – 2:22
Can We Live Healthy to 120 or 150?
- MHDr. Mark Hyman
So one of the key things I talk about in the book is mindset-
- LHLewis Howes
Mm
- MHDr. Mark Hyman
... you know, is how our minds really play a role in our longevity, and if we don't get that straight, we're screwed. Like, we, when people kill themselves by their thoughts. [upbeat music]
- LHLewis Howes
I think you gotta have a dream.
- LHLewis Howes
The school of greatness.
- LHLewis Howes
Really? [laughs]
- MHDr. Mark Hyman
Yeah.
- LHLewis Howes
Please welcome Lewis Howes.
- LHLewis Howes
Uh, you've got a book, Young Forever: The Secrets to Living Your Longest Healthiest Life. I'm curious, you've been studying this for a while now. You've gone all over the world and studied this with people who've lived the longest. You've been, you know, a doctor for many, many years. You've researched this stuff for a long time. Do you think it's possible to live in our 90s, in our 100s, fit, mentally sharp, healthy at that age still?
- MHDr. Mark Hyman
1,000%.
- LHLewis Howes
Really?
- MHDr. Mark Hyman
I mean, here's my plan. I wanna be 120, maybe 150. We'll see how it goes.
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
I wanna go for a hike in the mountains. I wanna swim in a cool lake with my love. I wanna go back to the cabin, make a beautiful dinner, have a glass of wine, make love, and just drift off into the neverland.
- LHLewis Howes
At 150?
- MHDr. Mark Hyman
[laughs] Yeah. Why not?
- LHLewis Howes
120, 150.
- MHDr. Mark Hyman
Actually, yes, 'cause, you know, what we see as aging, this country, is really abnormal aging. Decrepitude, decline, frailty, disease, disability, loss of cognitive function, faculties, and those are abnormal things that happen, and they don't have to happen. You know, I was in Sardinia and I met this guy, Pietro, who was 95 years old, and he had literally just stopped being a shepherd, where he was hiking up and down the mountains five miles a day, herding his sheep for, I don't know, 80 years probably. [laughs] And he was, like, straight up fit, strong, bellowing voice, super strong handshake, eyes clear. I'm like, man, you know, it's possible to be very vibrant if we know how to take care of ourselves. And what we've done in our culture is activate all of our disease systems and degradation and dysfunction. But we now know that we have an innate healing system, and we can activate our healing system. When I was in medical school, I studied a book called The Pathologic Basis of Disease.
- LHLewis Howes
Mm-hmm.
- MHDr. Mark Hyman
We never had a book called The Scientific Basis of Wellness. [laughs] Right? We never even took that class. But now we understand that the body has its ino- innate mechanisms for repair and healing, rejuvenation, renewal, that can be activated at any point in life.
- 2:22 – 6:11
A Sick Society: Chronic Disease and Longevity Science
- LHLewis Howes
Okay. So what are the disease systems that most of us are turning on throughout the world?
- MHDr. Mark Hyman
Well, so, so listen. We, we have, uh, an extraordinarily sick society. You know, America was 4% of the population of the world now, and, uh, it's 16% of the cases and deaths for COVID. Why?
- LHLewis Howes
So four... America is 4% of the population-
- MHDr. Mark Hyman
In the world
- LHLewis Howes
... of the world.
- MHDr. Mark Hyman
But we were 16% of the cases and deaths, four times what it should've been, and probably considering we have a great healthcare system, it should've been half of that, right?
- LHLewis Howes
Why, why is that, you think?
- MHDr. Mark Hyman
Yeah. Well, well it's not a question. It's an, it is a clear answer. It's because we are a very sick population. So we were pre-inflamed. We were overweight as a society. 93.2% of us are metabolically unhealthy, meaning we have high blood pressure, high cholesterol, high blood sugar, have had a heart attack or stroke, or are overweight.
- LHLewis Howes
Mm-hmm.
- MHDr. Mark Hyman
[laughs] That means 6.8% of us are healthy. So when COVID hits that population, who is obese and pre-inflamed, who is chronically ill, which is also a disease of inflammation, who is elderly, which is also a disease of inflammation, the COVID takes over and just kinda wipes these people out.
- LHLewis Howes
Mm.
- MHDr. Mark Hyman
And, and so we, we are suffering from diseases of, uh, heart disease, cancer, diabetes, dementia, all the things we see as people get older, and these are all entirely preventable. They just, they're relatively new. I mean, if you look back in the 150 years ago in all the hospital records in Mass General or the hospitals in Boston, diabetes was almost non-existent-
- LHLewis Howes
What?
- MHDr. Mark Hyman
... as a admitting diagnosis. So if there was a case of a heart attack, the entire, you know, medical school, the residents, the doctors, would all come around to see this rare case. It's like if somebody had, like, schistosomiasis today in a hospital-
- LHLewis Howes
Really?
- MHDr. Mark Hyman
... they'd come in and everyone, "What is this disease?" You know? Yeah, for sure. It was so unusual. So, uh, we now have a, a society where six in 10 of us have chronic disease, where four in 10 have more than one, where if you're over 65, you know, 80% have, have a chronic disease, and, and probably even more when you look at things a little more subtly about dysfunction that happens. So what we see as aging today is something that, uh, it gives us an impression that it's bad to get older because-
- LHLewis Howes
Yeah
- MHDr. Mark Hyman
... you're gonna become disabled, decrepit, dysfunctional, frail. But th- that's a model that is now being challenged by-
- LHLewis Howes
Wow
- MHDr. Mark Hyman
... researchers in longevity and who are proposing that we may be able to even create something called longevity escape velocity, meaning we can escape death by advancing science that will keep us living longer and longer each year we're alive.
- LHLewis Howes
Really?
- MHDr. Mark Hyman
Now, I'm not sure I'm, I'm into that [laughs] 'cause I don't know if I wanna live to be 1,000, but I do think that it, it is pushing the boundaries of what we thought is possible. And we know in animal models we've been able to extend life by a third, right? So if we, if we do certain interventions, we can take animals and make them live a third longer, which means for humans you'd live to be 120.
- LHLewis Howes
Mm.
- MHDr. Mark Hyman
So we've had women, uh, who've lived to be very old, like Madame Calment, who lived to be 122 years old, who was a French woman who was documented legitimately to be [laughs] 122 years old.
- LHLewis Howes
That's incredible.
- MHDr. Mark Hyman
It's incredible, and she was a, a wine-drinking, smoking chocoholic. [laughs] But I wouldn't follow her longevity plan. [laughs]
- LHLewis Howes
She had other things going for her to go against that, yeah.
- MHDr. Mark Hyman
Yeah, for sure. And so, so that was an anomaly, but there are, um, cases of, of very vital, healthy people, and I travel to the blue zones around the world where people live to be well over 100. I had, I had, I, I had... [laughs] saw this couple that had a combined age of 210.
- LHLewis Howes
Oh my gosh.
- MHDr. Mark Hyman
[laughs]
- 6:11 – 9:24
Ultra-Processed Food, Sugar, and Insulin Resistance
- LHLewis Howes
What are the, what would you say are the three to five main causes of our society that causes us to get overweight and get sick-
- MHDr. Mark Hyman
Yeah
- LHLewis Howes
... easily?
- MHDr. Mark Hyman
I mean, hands down, it's the food. You know-
- LHLewis Howes
Mm
- MHDr. Mark Hyman
... we are eating a diet, a toxic diet that is unlike anything we've eaten in human history. It's 60% of our calories are ultra-processed food, which means they're made from, uh, basically food-like substances that are from soy, corn, and wheat, and other additives and ingredients and fillers and colors and dyes and thickeners that are highly toxic to our systems. Uh, and they're inordinately high in sugar and starch. We've talked about this, but we eat about a pound a day of sugar and starch per person, per day in America, flour, sugar, and that's average. So [laughs] some people-
- LHLewis Howes
Right
- MHDr. Mark Hyman
... having a lot more, and it's just physiologically not something we evolved with. We used to eat 22 teaspoons a year as hunter gatherers if we were lucky to find a beehive or a berry patch. Now, we have that every day on average, and kids have, like 34, which is like 2 and 1/2 soda, like large sodas a day.
- LHLewis Howes
Right.
- MHDr. Mark Hyman
So that, that's what's driving a lot of this, and that drives this phenomenon called insulin resistance, which is at the heart of the aging process, and that insulin resistance causes-
- LHLewis Howes
Mm
- MHDr. Mark Hyman
... inflammation and all the age-related diseases. So-
- LHLewis Howes
What is insulin, for those who don't know what that is?
- MHDr. Mark Hyman
So insulin is, you know, what your pancreas makes in order to drop your blood sugar and keep your blood sugar balanced. So we, we all know Type 1 diabetics need to take insulin shots, but Type 2 diabetics ... I mean, by the way, there's, I think, been a 400% increase in Type 2 diabetes in kids [laughs] in the last 30 years, which is frightening to me. But they used to call it adult onset diabetes and they had to change the name because little kids were getting it.
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
You know, 15-year-olds are now getting liver transplants because of fatty liver from drinking too much soda. I mean, it- it is really scary stuff.
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
So, so insulin is important to keep your blood sugar in balance, but if you eat too much starch and sugar, your body pumps out more and more insulin. And then just like the boy who cried wolf, your cells don't pay attention anymore. You get resistant to the effects of insulin, and then you need more insulin, and that, you know, causes the deposition of belly fat.
- LHLewis Howes
Mm-hmm.
- MHDr. Mark Hyman
And belly fat is this dangerous fat around your organs that is not just holding up your pants, but it's pr- it's a whole organ itself. It's producing hormones and inflammatory molecules and neurotransmitters that are regulating your appetite. So it makes you really sick-
- LHLewis Howes
Mm
- MHDr. Mark Hyman
... and it's the central driver of all these age-related diseases. So that's a huge factor. There are other factors like toxins, our sedentary lifestyle, chronic stress, our sleep disruption. These are all things that are activating our disease systems, not our healing systems. So-
- LHLewis Howes
But the food is the main thing
- MHDr. Mark Hyman
... food is the, for sure, the main thing. Because, you know, think about it, you eat pounds of this stuff every day, and it's not just calories, it's information. So the molecules in the food make a difference. So in, in Ikaria, for example, one of the blue zones in Greece, they, they eat tons of wild food, wild greens. They have summer greens-
- LHLewis Howes
Mm
- MHDr. Mark Hyman
... winter greens, wild mushrooms. Every day they have wild sage tea because it's just free and cheap, right? They're poor over there [laughs]
- LHLewis Howes
Right, right,
- MHDr. Mark Hyman
So they all go out in the backyard and they pull up sa- [laughs] And it's like, turns out, I looked it up and it's full of catechins, which are these compounds in green tea that make green tea such a longevity compound, an antioxidant compound-
- LHLewis Howes
Mm
- MHDr. Mark Hyman
... an anti-inflammatory compound.
- 9:24 – 17:24
Foods for Longevity: Phytochemicals, Fats, and Protein vs. Fasting
- LHLewis Howes
What would you say the, the five main in- ingredients or foods to support longevity, whether it be like a, you know-
- MHDr. Mark Hyman
Well, this is great. It's a great question, right? So, so what should we be eating, right?
- LHLewis Howes
Mm-hmm.
- MHDr. Mark Hyman
We shouldn't be eating ultra-processed food. Process- uh, we shouldn't be eating too much starch and sugar. We shouldn't be eating refined oils. We shouldn't be eating additives and chemicals. We eat about five pounds of additives per person a year. We shouldn't be eating pesticides, herbicides, all that crap. So that's just a given. But what should we be eating? Well, start out with the most important things for longevity, which are these phytochemicals in plant foods. So the majority of your diet by volume should be colorful fruits and vegetables-
- LHLewis Howes
Mm-hmm
- MHDr. Mark Hyman
... and weird stuff if you can. You know, eat dandelion greens, eat seaweed, eat all this weird stuff because that's where all the medicine is.
- LHLewis Howes
Mm-hmm.
- MHDr. Mark Hyman
So the more colorful it is, the more heirloom it is, the more regenerative it is, the more organic it is, the more wild it is, the better it is. So if you had a wild strawberry, it's about the size of a, you know, a peanut, but it tastes like an explosion of flavor-
- LHLewis Howes
Mm-hmm
- MHDr. Mark Hyman
... if you ever ate a summer wild strawberry.
- LHLewis Howes
Sure, sure.
- MHDr. Mark Hyman
But you can go to the supermarket and buy these giant strawberries that look great, but then you put it in your mouth, it's like, "Mm, I think it's a strawberry." It's so sh-
- LHLewis Howes
[laughs]
- MHDr. Mark Hyman
You know, it's like-
- LHLewis Howes
More like an apple.
- MHDr. Mark Hyman
Yeah, like an apple, you know. [laughs]
- LHLewis Howes
[laughs]
- MHDr. Mark Hyman
But it's, it's not very tasty because-
- LHLewis Howes
Sure
- MHDr. Mark Hyman
... the, the phytochemicals aren't there.
- LHLewis Howes
Ah.
- MHDr. Mark Hyman
So we know that, uh, you want to include a rich array of these phytochemicals, and the special ones for longevity are things like fisetin that's in strawberries. From pomegranate, you can produce urolithin A, which improves your mitochondrial function. So you can have green tea, which is epigallocatechin gallate compounds, which I talked about the sage. You can have, uh, um, resveratrol, which is in red grapes, green skins.
- LHLewis Howes
Mm-hmm.
- MHDr. Mark Hyman
There's a lot, there's a lot of plant compounds that you can start to include. Curcumin, which is a powerful anti-inflammatory. So you can, you can have a wonderful time having a delicious diet.
- LHLewis Howes
Yeah.
- MHDr. Mark Hyman
And then, and then, um, mushrooms. They're not really a vegetable. I mean, they're its own category, and mushrooms have an incredible array of, uh, of compounds, these polysaccharides that, turn out, are immune modulating, anti-cancer, adaptogenic. And so we need to be including a lot more good mushrooms.
- LHLewis Howes
Okay.
- MHDr. Mark Hyman
And you can take mushrooms as supplements, but you can also eat a lot more of the good mushrooms. Uh, also garlic and onions are really important-
- LHLewis Howes
Mm
- MHDr. Mark Hyman
... for sulfur and the broccoli family specifically because they up-regulate glutathione, which is important for detox. Um, so you really wanna have a wide array of these-
- 17:24 – 20:02
Hyman's Transformation and the Tarahumara
- MHDr. Mark Hyman
I just changed my diet. It's... And I did a little bit of band resistance training.
- LHLewis Howes
Some resistance training, yeah.
- MHDr. Mark Hyman
I was always doing yoga, running, biking.
- LHLewis Howes
Mm-hmm.
- MHDr. Mark Hyman
I thought that's enough, but then I started doing a little bit resistance training. I started doing this strategy of, you know, this time-restricted eating, and then, and then adding a bunch of protein after my workouts-
- LHLewis Howes
Mm-hmm
- MHDr. Mark Hyman
... and it just, and it worked.
- LHLewis Howes
Now, what is, what's this-
- MHDr. Mark Hyman
You wanna, you wanna see?
- LHLewis Howes
Let's see it. Yeah, yeah, I do wanna see.
- MHDr. Mark Hyman
Wanna see? Okay, I'll show you.
- LHLewis Howes
You'll have to send it to me, well, I don't have the video today, yeah.
- MHDr. Mark Hyman
I'll, I'll send it to you. It's like, it's pretty, it's pretty wild, like I can't even quite believe it, you know?
- LHLewis Howes
Now, will the same strategy be at 60, in your 60s, as in your 80s?
- MHDr. Mark Hyman
Yeah, I think, you know, the po- the possibility of staying young longer is, is amazing. The, the research has shown that, that if you take even 60 years old, they can perform at the level of 30-year-olds if they're trained right.
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
So we don't have to lose that much function. And there's an amazing, uh, study on the Tarahumara Indians. The Tarahumara Indians live in Mexico-
- LHLewis Howes
Mm-hmm
- MHDr. Mark Hyman
... and they were really very, um... Here's, here's the picture of them.
- LHLewis Howes
Oh, my gosh.
- MHDr. Mark Hyman
[laughs]
- LHLewis Howes
That's crazy.
- MHDr. Mark Hyman
Yeah. [laughs] So- The Tarahumara Indians, uh-
- LHLewis Howes
Ah, yeah, we'll put it up on the screen for you to see
- MHDr. Mark Hyman
... had this belief that if you were older, you were a better runner. These were runners. They would run 100 miles a day, right? They would just do these ultra-marathons before there was anything like that. They would run from village to village, mountain to mountain.
- LHLewis Howes
Crazy.
- MHDr. Mark Hyman
And so they went down from Harvard, and they tested these people, and this is the power of mindset, right? And the beliefs and what that does. And so they believed that as you got older, you got better.
- LHLewis Howes
Ah, cool.
- MHDr. Mark Hyman
So the 20-year-olds are good, the 40-year-olds are better, and the 60-year-olds were better by every objective metric. Their pulmonary function test, their VO2 max, their, all their performance metrics that were objective, not just how fast they could run, but all the objective measures of fitness were better-
- LHLewis Howes
Mm
- 20:02 – 29:06
The Hallmarks of Aging and Biological Age
- MHDr. Mark Hyman
Yeah. And I, I think, I think the, the other, the other thing is to understand how to eat for your microbiome.
- LHLewis Howes
Mm-hmm.
- MHDr. Mark Hyman
Because we didn't, we didn't get into this yet, but there's a phenomena called the hallmarks of aging, which are these underlying things that go wrong as we age, and these are phenomena that seem to underlie all disease. So the idea is if you, if you treat these things, or if you correct these problems, called the hallmarks of aging, that it will dramatically extend life.
- LHLewis Howes
Mm.
- MHDr. Mark Hyman
So if we, if we cured all the cancer and heart disease from the planet, how many years extra do you think we'd live?
- LHLewis Howes
Phew. Um, probably an extra 10? I don't know.
- MHDr. Mark Hyman
Mm. Three to five.
- LHLewis Howes
Three to five, okay.
- MHDr. Mark Hyman
Maybe push it seven.
- LHLewis Howes
Okay.
- MHDr. Mark Hyman
If you address the hallmarks, we go to 120 or 150. So-
- LHLewis Howes
So if we eliminate diseases-
- MHDr. Mark Hyman
The number one and two killers in the world, we got rid of them, it's only gonna give us a few extra years of life.
- LHLewis Howes
Really?
- MHDr. Mark Hyman
Yeah.
- LHLewis Howes
Wow. What are the other hallmarks then?
- MHDr. Mark Hyman
Well, the, so the o- other hallmarks are really, well, driven around, uh, well, a- around these 10, I call, 10 things. One of them is the microbiome, and we'll get back to how to take care of your microbiome. But I'll just sort of list the hallmarks, and then we can come back to how to eat for your microbiome.
- LHLewis Howes
Okay. [laughs]
- MHDr. Mark Hyman
Um, but the, the first, the first thing is, that happens is you get damage to your DNA. So there's, every day there's little insults, toxins, the diet we're eating, whatever it is, stress, causing little death by a thousand cuts. But thank God you have a repair system. You know, you have a DNA repair system that goes out on a mission and starts to fix all the damages. Now, over time, you, you, you may have 99.9% fixing, but then there's that 1.1% that keeps getting worse over time. So that's one thing. Second is we get damage to our telomeres, which are these little, these little things at the end of our chromosomes that keep them safe and intact, and they shorten as we get older. And if they're too short, the cells stop replicating-
- LHLewis Howes
Mm
- MHDr. Mark Hyman
... and you die. Uh, then there's epigenetic changes, and epi- epigenetics are really important because it helps us distinguish between our chronological age and our biological age. So how, our chronological age is how long we're alive.
- LHLewis Howes
Mm-hmm.
- MHDr. Mark Hyman
I was born in 1959. I can't do anything about that. [laughs] I just can't. I'm 60, uh, 3 on the calendar, and I can't do anything about that. But my biological age-
- LHLewis Howes
Yeah
- MHDr. Mark Hyman
... is how old I am on the inside.
- LHLewis Howes
So how do we reverse the biolog- uh, the biological age while we continue to age chronologically?
- MHDr. Mark Hyman
That's the plan. So I did, I did my biological age, and I, at, at 62, and I was 43.
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
So biologically, I'm 43. I'm going for 25. But I'm chronologically 62.
- LHLewis Howes
That's crazy.
- 29:06 – 32:44
Eating for Your Microbiome and Eating with Joy
- MHDr. Mark Hyman
And the, the microbiome is really important, and it's not on the classic list of hallmarks of aging. I added it. But when you look at the literature, it's really clear that as we age, our microbiome degrades. We get what we call dysbiosis, imbalances in our gut bacteria, and those gut bacteria become toxic and inflammatory. So part of the diet you have to have is to take care of your inner garden. Mm-hmm. You need pre and probiotic foods and polyphenols. So prebiotic foods are things like, you know, asparagus, artichokes, Jerusalem artichokes, jicama, uh, plantains. These are foods that feed the good bacteria, right? And then there's probiotic foods. Sauerkraut, kimchi, miso, tempeh. These ancient foods that have been around forever that are fermented foods, that are prebiotic foods. I grew up on pickles, I'm Jewish. I didn't even know that was a probiotic food [laughs] until recently. Yeah. [laughs] And then, and then there's polyphenols, and this is an incredible discovery, that there are certain compounds in plants that your gut bacteria love. So you're not only eating for yourself, you're eating for the trillions of microbes- Mm-hmm ... that almost outnumber your cells in your gut. Right. And those microbes, when they're bad, cause inflammation and disease and diabetes and cancer and everything else. But when they're good, they regulate inflammation, they help you stay healthy. It's super important to feed them right. So you have to learn how to tend your inner garden. Mm-hmm. And there's a couple of ones that are really important, like green tea, pomegranate, cranberry. Um, and pomegranate's an interesting one. I talk about this in the book. Most people have pretty crappy microbiomes, uh, pun intended. [laughs] And the, the truth is that you, you've lost a lot of important species that you need to work with your diet to make good stuff. So- If you eat pomegranate, it has a compound in it that gets converted by good gut bacteria to something called urolithin A. Now, urolithin A-
- LHLewis Howes
Mm
- MHDr. Mark Hyman
... you might not have heard about, but you will. It's really amazing, and there's m- millions of dollars of research on this compound that is derived from pomegranate being metabolized by your gut bacteria and producing this compound. But you could also make it and give it externally. And, and in, in studies they found that without exercise, it increases fitness level through VO2 max, increases muscle strength, and increases, uh, mitochondrial-
- LHLewis Howes
Wow
- MHDr. Mark Hyman
... uh, cleanup or, uh, mitochondrial autophagy.
- LHLewis Howes
Without exercise.
- MHDr. Mark Hyman
Without exercise. And also increases, uh, mitochondrial renewal and re- and biogenesis to make new mitochondria. So basically you're taking... think about it, you're taking this, like, pomegranate, your gut's metabolizing it and you create this magical longevity-
- LHLewis Howes
Hm
- MHDr. Mark Hyman
... compound. And that's just one example.
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
Right? So we need to feed our gut bacteria with lots of these colorful vegetables.
- LHLewis Howes
That's beautiful.
- MHDr. Mark Hyman
Yeah.
- LHLewis Howes
Wow, okay. So eat for your microbiome is something you said to come back to. Is that what we're talking about here?
- MHDr. Mark Hyman
We just did.
- LHLewis Howes
And then what would be the fifth thing to add to this?
- MHDr. Mark Hyman
I think, I think, you know, the, uh-
- LHLewis Howes
Five main things, foods for longevity.
- MHDr. Mark Hyman
Yeah, I think, you know, um, I probably would say it would be, uh, eating with joy. You know, because-
- LHLewis Howes
No, I love that
- MHDr. Mark Hyman
... I think, I think people get so screwed up about food and get so obsessive and so, uh, rigid about it that, you know, part of the key is celebration-
- LHLewis Howes
Mm
- MHDr. Mark Hyman
... enjoyment, you know. It's my birthday soon, I'm having a crew over or we're having a friends Thanksgiving. You know, it's gonna be yummy and delicious, we're probably gonna overeat.
- LHLewis Howes
[laughs]
- MHDr. Mark Hyman
There's definitely gonna be some pecan pie.
- LHLewis Howes
Oh, man.
- MHDr. Mark Hyman
You know? [laughs]
- LHLewis Howes
Sounds incredible.
- MHDr. Mark Hyman
So that's okay. So I think we shouldn't be too rigid, but I think the key of community and eating with joy and eating with pleasure and savoring your food and it, it's really, really important.
- LHLewis Howes
Mm-hmm.
- 32:44 – 40:20
Lessons from the Blue Zones: Wild Food, Community and Purpose
- LHLewis Howes
What was the things that you saw when you went to these Blue Zones that they did that maybe you weren't even thinking they would do? Like, what were the surprising things they did?
- MHDr. Mark Hyman
Well-
- LHLewis Howes
Or the unsurprising things they did.
- MHDr. Mark Hyman
Yeah, I mean, well, well, the few things I saw that were kind of, kind of striking to me that made sense, but one was that in, in, in Ikaria, which was one of the Greek Blue Zones, they eat so much wild food. So they had wild greens, summer greens, winter greens. They had wild mushrooms, they had wild sage tea, they had wild fish. They had so much wild food in their diet.
- LHLewis Howes
Hm.
- MHDr. Mark Hyman
And it, and we know that wild foods are much more nutrient-dense. Why? Because they're stressed, and stressed plants make more protective compounds. Those protective compounds are called phytochemicals. They give the color and the richness and the flavor.
- LHLewis Howes
Mm-hmm.
- MHDr. Mark Hyman
And what people don't understand is the more flavorful a food is naturally, the more phytochemicals it has.
- LHLewis Howes
Interesting.
- MHDr. Mark Hyman
You know, if you go to your garden at the end of August and pick a cherry tomato that's ripened in the hot sun that explodes in your mouth, like, the most incredible flavor. But if you go to a store-bought tomato and you cut it, it's like cardboard, tasteless. What's the difference? It's the phytochemicals. So flavor always follows the phytochemical richness of a food. So, so not the stuff you put on it or sauces or salt or fat or sugar to make it taste better, which food industry does.
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
But just the natural flavor.
- LHLewis Howes
Interesting.
- MHDr. Mark Hyman
So, so you know, the more flavorful a food is, the better it is.
- LHLewis Howes
Hm.
- MHDr. Mark Hyman
So, uh, it's, it... wild- they eat a lot of wild food, and it's so flavorful. Uh, the other thing was, uh, interesting was that shepherds, um, you know, had this culture of, of going and knowing exactly which plants to feed their animals at which time of year-
- LHLewis Howes
Hm
- MHDr. Mark Hyman
... to graze them. So would shepherd them, they'd eat all these wild plants, but they know if they, this was, this herb was coming in at this time of year, they'd go eat this herb. And if this plant was coming in this time of year, they'd go eat that thing. I'm like, "Why are you doing this?" He says, "We know be- because the meat and the milk tastes better when we"-
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
"When we..." Yeah. And so it, it kind of... you know, they were not doing it 'cause it, it was better for them or 'cause it was for longevity or because-
- LHLewis Howes
Tastes better
- MHDr. Mark Hyman
... right, the cheese... yeah, tastes better. So i- it turns out that we know now that phytochemicals are not just in plants, and phyto means plant, right? They're not just in plants, they're also in animals.
- LHLewis Howes
Hm.
- MHDr. Mark Hyman
So the work of Fred Provenza and Stephen DeBette from Duke have clearly shown that when animals are eating a wide array of wild plants or a wide array of, you know, you know, planted grasses and flowers and different things, they will seek out medicine in the food. So they will literally go and eat major, like, you know, calorie crops, let's say, but then they'll go and sample from, like, 100 different plants to get their medicines.
- LHLewis Howes
Hm.
- MHDr. Mark Hyman
And so these, these wild animals, these wild plants are being eaten, and the phytochemicals are accumulating in the meat and the milk of these animals. So studies have shown, for example, that you can have as high levels of the catechins in green tea in goat milk that's from goats eating certain wild plants.
- LHLewis Howes
Really?
- MHDr. Mark Hyman
Yeah. So it's mind- mind-blowing, and there may be ways that even these get transmuted. So eating regeneratively raised meat. I went to a restaurant here in LA, uh, last night called Matu where they have regeneratively raised meat.
- LHLewis Howes
Was it amazing?
- MHDr. Mark Hyman
It was amazing. Now, it wasn't as, like, fatty and, like, kind of like marble-like corn-fed meat-
- 40:20 – 47:47
Mind, Stress, Meaning, and Loneliness
- LHLewis Howes
Why, why... Can you live long and still-
- MHDr. Mark Hyman
Hustle? [laughs]
- LHLewis Howes
... hustle or just want more, want to build something greater in your life?
- MHDr. Mark Hyman
I think you can. I think, I think it's really about, you know, what happens on the inside because-
- LHLewis Howes
Yeah
- MHDr. Mark Hyman
... you know, one of the biggest, uh, things that regulates your epigenome is your mind. So your, your biggest pharmacy in your body is between your ears.
- LHLewis Howes
Mm.
- MHDr. Mark Hyman
It's the most powerful pharmacy in the world.
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
And you can activate it for good or bad. So when we are having thoughts that are, um, you know, uh, uh, stressful thoughts, when we're in toxic relationships, when we're worried or anxious, when we aren't in, you know, harmony with ourselves, it activates all these really nasty pathways that drive inflammation and harm your mitochondria and dest- I mean, your microbiome is listening in on your thoughts.
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
It's eavesdropping. So those bugs don't like it when you are not happy.
- LHLewis Howes
Really?
- MHDr. Mark Hyman
Yeah. [laughs]
- LHLewis Howes
What, what is the process of that from an idea, a thought into the mitochondria? How does that transfer into a healthy, uh, information into a physical manifestation versus unhealthy information, data in a thought into physical-
- MHDr. Mark Hyman
Well, well-
- LHLewis Howes
... unhealth?
- MHDr. Mark Hyman
So what, what's the biochemistry of it? Well, well, for example, um, if you're stressed, you're producing cortisol and adrenaline and all these other hormones and proteins that then will trigger a whole cascade of downstream effects that activate, uh, transcription factors, that, that transcription factors-
- LHLewis Howes
Mm
- MHDr. Mark Hyman
... that turn on genes, that cause inflammation and all these other problems. So you're basically, you know, creating inflammatory thoughts are creating inflammation in your body, literally. And-
- LHLewis Howes
Isn't that crazy?
- MHDr. Mark Hyman
And you have-
- LHLewis Howes
That's-
- MHDr. Mark Hyman
... receptors on your s- like immune cells, for example, for neurotransmitters. So if, if you're stressed, your immune system is eavesdropping on your thoughts.
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
That's why if you're stressed, you are more likely to have an infection or get sick or have other bad health consequences.
- LHLewis Howes
Why do you think it is that our body is built this way that a thought can either make us feel and physically transform into joy and health-
- MHDr. Mark Hyman
Mm
- LHLewis Howes
... or feel sick and then become sick? Why do you think our body-
- MHDr. Mark Hyman
Why, from an evolutionary point of view? How do we-
- 47:47 – 57:49
What Functional Medicine Is, Gut Health, and a Patient Case
- LHLewis Howes
If you enjoyed that interview, then I know you'll love what we have coming up right now. Let's go back to functional medicine.
- MHDr. Mark Hyman
Yeah, yeah.
- LHLewis Howes
What does that actually mean?
- MHDr. Mark Hyman
So functional medicine is, is-
- LHLewis Howes
Compared to regular medicine.
- MHDr. Mark Hyman
Yeah, yeah. Well, you know, my, uh... I don't know if people listening really have a great understanding of-
- LHLewis Howes
Sure
- MHDr. Mark Hyman
... like, what's happening right now in science.
- LHLewis Howes
Uh-huh.
- MHDr. Mark Hyman
But it's profound, that the shift that's happening in our understanding of the body is, it's like Columbus going, "Hey, the earth isn't flat."
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
And, uh-
- LHLewis Howes
Right now, the last few years.
- MHDr. Mark Hyman
Right. It's just, like the last decade or two-
- LHLewis Howes
Okay
- MHDr. Mark Hyman
... with our understanding of the human genome, of systems biology, of the body as a biological network-
- LHLewis Howes
Mm-hmm
- MHDr. Mark Hyman
... as a system. It's like an ecosystem where everything's connected, working together. And so the way we organize medicine is according to these organs. You know, you've got your cardiovascular system, your neurologic system, your GI system, your, you know... And so you go to all these specialists.
- LHLewis Howes
Right.
- MHDr. Mark Hyman
Right? Everyb- And, and, and everybody treats your, their part of your body. If you have a migraine, we're actually learning that it might be related to gut flora, but-
- LHLewis Howes
Wow
- MHDr. Mark Hyman
... or if you have heart att- if, I mean, now we know that your, you might be getting cancer 'cause of your gut bacteria. Well, no oncologist is asking you what's going on in your gut microbiome. [laughs]
- LHLewis Howes
Right.
- MHDr. Mark Hyman
And so now we know, for example, like the microbiome is a great example of this disruption that's happening in healthcare. You know, the microbiome- Which is your gut flora. It's really, it's like, uh, 10 times as many cells as your own cells. It's 100 times as much DNA as your own DNA.
- LHLewis Howes
Huh.
- MHDr. Mark Hyman
So I, we're kind of lazy. We have about as much DNA as an earthworm.
- LHLewis Howes
Okay. [laughs]
- MHDr. Mark Hyman
But we borrow the DNA of the bicromes, the microbes in our gut, to do things for us. And we, we, we borrow things from plants to do things from us, like s- like-
- LHLewis Howes
Hmm
- MHDr. Mark Hyman
... for example, glucosinolates. And so the, the microbiome is this huge thing that's got two to three million genes. We only have 20,000 genes, and it regulates-
- 57:49 – 1:07:50
Practical Reset Programs, Fasting Tips, and Why He Became a Doctor
- LHLewis Howes
So if someone is listening, and they're on some type of a medication, or they're just feeling, like, constantly sick-
- MHDr. Mark Hyman
Mm-hmm, mm-hmm
- LHLewis Howes
... you know, something's just constantly happening to them, what do you think is ... You know, 'cause there's so much information online that it's scary.
- MHDr. Mark Hyman
So it's scary, right. Well, here's what I would say.
- LHLewis Howes
You know, the letter D stuff, just, like-
- MHDr. Mark Hyman
Yeah
- LHLewis Howes
... looking up anything-
- MHDr. Mark Hyman
Yeah
- LHLewis Howes
... and Googling it, and seeing all the nasty photos of, and just being like, "Ugh."
- MHDr. Mark Hyman
Yeah, right.
- LHLewis Howes
What is an approach that someone should take if they have some challenge that's constantly happening in their health? Should they first analyze the food they're intaking-
- MHDr. Mark Hyman
Mm-hmm
- LHLewis Howes
... and do, like, an analysis? Do you have, like, a process?
- MHDr. Mark Hyman
Absolutely, abs ... This is a great question, Lewis. So, you know, what I am is a doctor, and what I do is see patients in my office. That's my main job.
- LHLewis Howes
Yeah.
- MHDr. Mark Hyman
Yes, I've written a dozen books. Yes, I do a lot of stuff, but that's my main job.
- LHLewis Howes
Yeah.
- MHDr. Mark Hyman
And, and so I've learned over 30 years of doing this how to create sustainable, practical programs to help people get from sick to well-
- LHLewis Howes
Mm
- MHDr. Mark Hyman
... very quickly. And what I've done, because not everybody can come see me, and there aren't that many of us out there yet-
- LHLewis Howes
You only have so many hours in the day [laughs]
- MHDr. Mark Hyman
... and there's so, not that many functional medicine ... So I've written books and programs-
- LHLewis Howes
Yes
- MHDr. Mark Hyman
... to help people operationalize this in their own life.
- LHLewis Howes
Yes.
- MHDr. Mark Hyman
So Eat Fat, Get Thin, I mean, look, I'm, you know, you know, I could say, you know, "Do my program," but, like, I'm not, I don't really care what program you do.
- LHLewis Howes
Right.
- MHDr. Mark Hyman
As long as it's based on the basic principles, and there are a lot of my colleagues who are writing great books about this. It's all-
- LHLewis Howes
Yes
- MHDr. Mark Hyman
... it's all the same information-
- 1:07:50 – 1:18:09
Policy Changes to Fix the Food System
- LHLewis Howes
I like it. I got three questions for you. One is if you had an unlimited amount of money that you could spend on one thing to, to cure one thing in the world, what would that be?
- MHDr. Mark Hyman
One disease or one-
- LHLewis Howes
One thing in the world that you think-
- MHDr. Mark Hyman
Ah
- LHLewis Howes
... needs curing.
- MHDr. Mark Hyman
Um.
- LHLewis Howes
Or solving one issue.
- MHDr. Mark Hyman
Oof, gosh, I mean, that's, so many things flooded into me-
- LHLewis Howes
[laughs]
- MHDr. Mark Hyman
... when you said that. I mean, I think, um, you know, the thing that I think is driving so many of our economic and social ills is our food system. And, and if I had a magic wand-
- LHLewis Howes
Mm-hmm
- MHDr. Mark Hyman
... I would put in a... And I, I'm working actually on a petition right now to, I've got 150,000 people on our Fat Summit, which is an online-
- LHLewis Howes
Right
- MHDr. Mark Hyman
... summit on, and we're ex- interview over 30 experts on fat. And it's available. Anybody can go to fatsummit.com and get to see this.
- LHLewis Howes
Yeah.
- MHDr. Mark Hyman
And, and, you know, to kind of list what are the policies that would really radically change things, not just in America but around the world, if we became the, the, the beacon for this. Um-
- LHLewis Howes
Mm-hmm
- MHDr. Mark Hyman
... and I met with the surgeon general a couple of days ago, and he asked me to come to Washington to help change and shape this policy. So the things that matter are, you know, ending food subsidy, e- ending s- agricultural subsidies for commodity products like corn-
- LHLewis Howes
Yeah
- MHDr. Mark Hyman
... soy, and wheat that go into all our processed industrial food. Subsidizing fruits and vegetables and things that actually promote health.
- LHLewis Howes
Yeah.
- MHDr. Mark Hyman
Ending food marketing to kids, right? We, we, we-
- LHLewis Howes
All the cereals and sugar and pop
- MHDr. Mark Hyman
... market junk food to kids. I think we're one of only 50 countries that, that, that, uh, uh, that we are, one, one of the only countries that doesn't do this. 50 countries control food marketing to kids.
- LHLewis Howes
Really?
- MHDr. Mark Hyman
Regulate. Yeah.
- LHLewis Howes
They don't-
- MHDr. Mark Hyman
Us and Syria, no, are the only ones I think. [laughs]
- LHLewis Howes
Oh my gosh.
- MHDr. Mark Hyman
I would, uh, end all use of antibiotics in animal feed except, except in animal husbandry except for treatment of disease.
- 1:18:09 – 1:26:59
Diabetes, Food Causes of Disease, and Industry Influence
- LHLewis Howes
So let's go back to diabetes for a second. Tell me again the stat on diabetes, how many people have it-
- MHDr. Mark Hyman
Yeah
- LHLewis Howes
... or are pre-diabetic.
- MHDr. Mark Hyman
Okay. Yes.
- LHLewis Howes
And, and what, I'm undereducated on this, so how many different types of diabetes are there?
- MHDr. Mark Hyman
Okay, good.
- LHLewis Howes
And how is it caused?
- MHDr. Mark Hyman
Okay. Okay. So type 1 diabetes is an autoimmune disease. Pancreas fails. It's called ju- we used to call it juvenile diabetes. Uh, and you need insulin. It's just, it's-
- LHLewis Howes
You need it
- MHDr. Mark Hyman
... it's, you need insulin. But you-
- LHLewis Howes
If you have type 1 diabetes, you need insulin.
- MHDr. Mark Hyman
You need insulin, yeah.
- LHLewis Howes
To do what?
- MHDr. Mark Hyman
'Cause your pancreas dies. 'Cause your pancreas makes insulin and helps your blood sugar, uh, get balanced, keeps, that's the blood, it's sort of the gatekeeper that lets the, the glucose into your cells.
- LHLewis Howes
Okay.
- MHDr. Mark Hyman
So it's really important. Um, and-
- LHLewis Howes
So how does that die? How, what happens-
- MHDr. Mark Hyman
Can people die from that?
- LHLewis Howes
I mean, how does the pancreas die?
- MHDr. Mark Hyman
Oh, well, it's an autoimmune-
- LHLewis Howes
How does it get to that point?
- MHDr. Mark Hyman
It's an autoimmune, like an auto- like you get multiple sclerosis or rheumatoid arthritis.
- LHLewis Howes
Gotcha.
- MHDr. Mark Hyman
It's, it's basically your body attacks your pancreas. And, and-
- LHLewis Howes
Is that from eating a lot of bad foods?
- MHDr. Mark Hyman
Uh, well, there's been links to dairy, and actually as an, a driver of-
- LHLewis Howes
Wow
- MHDr. Mark Hyman
... type 1, uh, diabetes. Gluten, 29% of people who have type 1 diabetes have celiac that are undiagnosed.
- LHLewis Howes
Wow.
- MHDr. Mark Hyman
So, uh, celiac is a big cause of autoimmune diseases-
- 1:26:59 – 1:37:30
Dairy, Nut Milks, Food Diversity, and the 10-Day Reset
- LHLewis Howes
I'm curious, you said something about nut milk, uh, and about dairy.
- MHDr. Mark Hyman
Yeah.
- LHLewis Howes
Dairy, has dairy been declining-
- MHDr. Mark Hyman
Yeah, dairy-
- LHLewis Howes
... in the last five years?
- MHDr. Mark Hyman
Yes, dairy consumption-
- LHLewis Howes
Do you know the-
- MHDr. Mark Hyman
... has been declining dramatically.
- LHLewis Howes
Do you know the percentages or the-
- MHDr. Mark Hyman
Uh, it's, like, yeah, I think, you know, over the last few years, like, it's gone down about 25%. Borden, uh, which is a big milk producer, has been around since 18, I think, 87, has gone bankrupt.
- LHLewis Howes
What?
- MHDr. Mark Hyman
Yeah. The, a lot, and then a lot of these bu- milk producers. Now people are still eating cheese.
- LHLewis Howes
Yeah.
- MHDr. Mark Hyman
They're eating yogurt, they're eating these, but, but actual milk, uh, consumption has gone down, and the-
- LHLewis Howes
Is that-
- MHDr. Mark Hyman
... nut milks have gone up.
- LHLewis Howes
Why is that?
- MHDr. Mark Hyman
I think-
- LHLewis Howes
Is that because of education? Is that because of disease-
- MHDr. Mark Hyman
I think, you know-
- LHLewis Howes
... that-
- MHDr. Mark Hyman
[laughs] I think probably a lot of reasons.
- LHLewis Howes
Okay.
- MHDr. Mark Hyman
75% of the population is lactose intolerant.
- LHLewis Howes
Yeah.
- MHDr. Mark Hyman
So they don't feel good. Uh, you should-
- LHLewis Howes
I used to drink m- so much milk every day as a kid.
- MHDr. Mark Hyman
And how did you feel? Fine?
- LHLewis Howes
I always had, like, a stuffy nose. [laughs]
- MHDr. Mark Hyman
Right. Right.
Episode duration: 1:37:30
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