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Demis Hassabis on Lex Fridman: How AlphaFold Changed Biology

Hassabis conjectures any pattern shaped by nature is learnable by classical systems; alphafold solved protein folding while veo models fluid dynamics passively.

Lex FridmanhostDemis Hassabisguest
Jul 23, 20252h 28mWatch on YouTube ↗

CHAPTERS

  1. 0:00 – 1:21

    Episode highlight

  2. 1:21 – 2:06

    Introduction

  3. 2:06 – 5:48

    Learnable patterns in nature

  4. 5:48 – 14:26

    Computation and P vs NP

  5. 14:26 – 18:50

    Veo 3 and understanding reality

  6. 18:50 – 30:52

    Video games

  7. 30:52 – 36:53

    AlphaEvolve

  8. 36:53 – 41:17

    AI research

  9. 41:17 – 46:00

    Simulating a biological organism

  10. 46:00 – 52:15

    Origin of life

  11. 52:15 – 1:03:01

    Path to AGI

  12. 1:03:01 – 1:06:17

    Scaling laws

  13. 1:06:17 – 1:09:04

    Compute

  14. 1:09:04 – 1:13:00

    Future of energy

  15. 1:13:00 – 1:17:54

    Human nature

  16. 1:17:54 – 1:35:53

    Google and the race to AGI

  17. 1:35:53 – 1:42:27

    Competition and AI talent

  18. 1:42:27 – 1:48:53

    Future of programming

  19. 1:48:53 – 1:58:07

    John von Neumann

  20. 1:58:07 – 2:02:50

    p(doom)

  21. 2:02:50 – 2:05:56

    Humanity

  22. 2:05:56 – 2:12:06

    Consciousness and quantum computation

  23. 2:12:06 – 2:19:20

    David Foster Wallace

  24. 2:19:20 – 2:28:14

    Education and research

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