Lex Fridman PodcastDmitry Korkin: Computational Biology of Coronavirus | Lex Fridman Podcast #90
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Episode Details
EPISODE INFO
- Released
- April 22, 2020
- Duration
- 2h 9m
- Channel
- Lex Fridman Podcast
- Watch on YouTube
- ▶ Open ↗
EPISODE DESCRIPTION
Dmitry Korkin is a professor of bioinformatics and computational biology at Worcester Polytechnic Institute, where he specializes in bioinformatics of complex disease, computational genomics, systems biology, and biomedical data analytics. I came across Dmitry's work when in February his group used the viral genome of the COVID-19 to reconstruct the 3D structure of its major viral proteins and their interactions with human proteins, in effect creating a structural genomics map of the coronavirus and making this data open and available to researchers everywhere. We talked about the biology of COVID-19, SARS, and viruses in general, and how computational methods can help us understand their structure and function in order to develop antiviral drugs and vaccines. Support this podcast by signing up with these sponsors:
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EPISODE LINKS: Dmitry's Website: http://korkinlab.org/ Dmitry's Twitter: https://twitter.com/dmkorkin Dmitry's Paper that we discuss: https://bit.ly/3eKghEM PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ Full episodes playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 Clips playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOeciFP3CBCIEElOJeitOr41 OUTLINE: 0:00 - Introduction 2:33 - Viruses are terrifying and fascinating 6:02 - How hard is it to engineer a virus? 10:48 - What makes a virus contagious? 29:52 - Figuring out the function of a protein 53:27 - Functional regions of viral proteins 1:19:09 - Biology of a coronavirus treatment 1:34:46 - Is a virus alive? 1:37:05 - Epidemiological modeling 1:55:27 - Russia 2:02:31 - Science bobbleheads 2:06:31 - Meaning of life CONNECT:
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SPEAKERS
Lex Fridman
hostDmitry Korkin
guest
EPISODE SUMMARY
In this episode of Lex Fridman Podcast, featuring Lex Fridman and Dmitry Korkin, Dmitry Korkin: Computational Biology of Coronavirus | Lex Fridman Podcast #90 explores Decoding Coronavirus: Computational Maps, Viral Evolution, and Pandemic Control Lex Fridman talks with computational biologist Dmitry Korkin about how bioinformatics and structural genomics are being used to understand SARS-CoV-2 and related viruses.
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