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Paola Arlotta: Brain Development from Stem Cell to Organoid | Lex Fridman Podcast #32

Paola Arlotta is a professor of stem cell and regenerative biology at Harvard University. She is interested in understanding the molecular laws that govern the birth, differentiation and assembly of the human brain’s cerebral cortex.

Lex FridmanhostPaola Arlottaguest
Aug 12, 201957mWatch on YouTube

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Episode Details

EPISODE INFO

Released
August 12, 2019
Duration
57m
Channel
Lex Fridman Podcast
Watch on YouTube
▶ Open ↗

EPISODE DESCRIPTION

Paola Arlotta is a professor of stem cell and regenerative biology at Harvard University. She is interested in understanding the molecular laws that govern the birth, differentiation and assembly of the human brain’s cerebral cortex. She explores the complexity of the brain by studying and engineering elements of how the brain develops. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep32-sb See below for timestamps, and to give feedback, submit questions, contact Lex, etc. *CONTACT LEX:* *Feedback* - give feedback to Lex: https://lexfridman.com/survey *AMA* - submit questions, videos or call-in: https://lexfridman.com/ama *Hiring* - join our team: https://lexfridman.com/hiring *Other* - other ways to get in touch: https://lexfridman.com/contact *OUTLINE:* 0:00 - Introduction 1:05 - How unlikely is the human brain? 5:28 - Brain development process 13:57 - Brain development organization as a distributed vs centralized system 20:08 - Nature vs nurture, hardware vs software 22:38 - Brain organoids 36:40 - Our place in the history of understanding the brain 39:45 - Building a human brain 42:45 - Ethics 49:02 - Lessons from raising kids 52:14 - How has studying the brain changed your understanding of self? 54:08 - Merging with AI *PODCAST LINKS:*

*SOCIAL LINKS:*

SPEAKERS

  • Lex Fridman

    host
  • Paola Arlotta

    guest

EPISODE SUMMARY

In this episode of Lex Fridman Podcast, featuring Lex Fridman and Paola Arlotta, Paola Arlotta: Brain Development from Stem Cell to Organoid | Lex Fridman Podcast #32 explores Harvard neuroscientist decodes human brain development using lab-grown organoids Lex Fridman talks with Paola Arlotta, a Harvard professor studying how the human cerebral cortex is built from stem cells, both in embryos and in lab-grown brain organoids.

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