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The Mel Robbins PodcastThe Mel Robbins Podcast

Mayo Clinic Dermatologist: 5 Small Habits for Healthier, Younger, and Amazing Skin

You are getting the ultimate guide to skincare and skin health. In today’s episode, a Mayo Clinic dermatologist will reveal the 5 small habits for healthier, younger, and more radiant skin. Whether you're dealing with dry skin, wrinkles, dark spots, acne, thinning hair, or your skin suddenly seems to be aging overnight, this episode is for you. Dr. Saranya Wyles, MD PhD, one of the leading dermatologists and physician-scientists at Mayo Clinic, is here with the science, the 5 specific things you can do to improve your skin health, and the truth about what works… and what doesn't. Dr. Wyles studies the connection between your skin, aging, and overall health. And she's going to change the way you think about skincare. Because your skin isn't just about how you look. It's the largest organ in your body, and it can serve as a check engine light for your health. What your skin may be telling you about inflammation, hormones, and underlying health conditions. What helps your skin repair itself and what accelerates aging. What's worth your money and what isn't. In today's episode, you're going to learn how to recognize important changes in your skin, protect it as you age, and take better care of your overall health. Dr. Wyles covers everything from collagen and skin aging to hormones, inflammation, sunscreen, skincare products, and the latest treatments everyone's talking about online. And she doesn't just tell you what might be wrong. She gives you clear, science-backed steps you can take to protect your skin and support your health. In this episode, you'll learn: - The warning signs in your skin you shouldn't ignore - How certain skin conditions may be connected to heart disease, diabetes, and inflammation - The 5 small habits that support healthier skin and better aging - What happens to your skin during perimenopause and menopause, and what you can do about it - How sleep, stress, nutrition, and exercise affect the way your skin looks and functions - What the research says about peptides, red light therapy, and popular anti-aging treatments - The difference between mineral, chemical, and tinted sunscreen, and which one to use - How to simplify your morning and nighttime skincare routines If you put what Dr. Wyles teaches you into practice, you'll stop guessing, stop chasing skincare trends, and start taking better care of your skin and your overall health. For more resources related to today’s episode, click here for the podcast episode page: https://www.melrobbins.com/episode/episode-447/ Follow The Mel Robbins Podcast on Instagram: https://www.instagram.com/themelrobbinspodcast I’m just your friend. I am not a licensed therapist, and this podcast is NOT intended as a substitute for the advice of a physician, professional coach, psychotherapist, or other qualified professional. Got it? Good. I’ll see you in the next episode. 00:00 Meet the Guest 02:24 What Your Skin Reveals About Your Overall Health 10:48 How Your Skin Ages 18:07 The 5 Small Things You Can Do Right Now to Improve Your Skin 19:26 Why Sleep Is One of the Best Things You Can Do for Your Skin 28:01 What to Eat for Healthier, Younger-Looking Skin 33:31 The Glowing Skin Smoothie 38:12 How Much Water Do You Really Need for Healthy Skin? 39:34 How to Choose a Moisturizer That Works 43:16 How Exercise Helps Your Skin Stay Healthy as You Age 46:57 What Stress Is Doing to Your Skin 51:36 What Your Nails Say About Your Health 52:42 Truth About Peptides: What Works and What's Hype 57:39 Sunscreen: What You Need to Know to Protect Your Skin 1:04:42 Signs of Skin Aging: What's Normal and What You Shouldn't Ignore 1:15:46 You Can Build Healthier Skin — Follow Mel: Instagram: https://www.instagram.com/melrobbins/ TikTok: http://tiktok.com/@melrobbins Facebook: https://www.facebook.com/melrobbins LinkedIn: https://www.linkedin.com/in/melrobbins Website: http://melrobbins.com​ — Sign up for Mel’s newsletter: https://melrob.co/sign-up-newsletter A note from Mel to you, twice a week, sharing simple, practical ways to build the life you want. — Subscribe to Mel’s channel here: https://www.youtube.com/melrobbins​?sub_confirmation=1 — Listen to The Mel Robbins Podcast 🎧 New episodes drop every Monday & Thursday! https://melrob.co/spotify https://melrob.co/applepodcasts https://melrob.co/amazonmusic — Looking for Mel’s books on Amazon? Find them here: The Let Them Theory: https://amzn.to/3IQ21Oe The Let Them Theory Audiobook: https://amzn.to/413SObp The High 5 Habit: https://amzn.to/3fMvfPQ The 5 Second Rule: https://amzn.to/4l54fah

Dr. Saranya WylesguestMel Robbinshost
Oct 17, 20261h 24mWatch on YouTube ↗

EVERY SPOKEN WORD

  1. 0:00 – 2:24

    Meet the Guest

    1. SW

      Your skin is your check engine light. This is not vanity. This is actually a reflection of your health.

    2. MR

      Today, on The Mel Robbins Podcast, trailblazing Mayo Clinic Dermatologist and Physician Scientist, Dr. Saranya Wyles is here.

    3. SW

      Skincare is healthcare. I want you to be concerned about changes in your skin. You have the power to influence your health, autoimmune dysfunction, kidney disease, diabetes. How you look, also known as your perceived age, can influence a lot of downstream health risk factors. Are you ready-

    4. MR

      Oh, God

    5. SW

      ... for the true skin age-

    6. MR

      Okay

    7. SW

      ... of-

    8. MR

      Oh, [beep] . Oh my God, I'm not ready to be that old.

    9. SW

      The good news is that your skin can reset. [upbeat music]

    10. MR

      I wanna invite you to stick around later in the episode to hear all about something called the clean slate, brought to you by our new sponsor, Mrs. Meyers. It's something that will help you clear up both physical and mental space, and you're gonna absolutely love this. Please help me welcome Dr. Saranya Wyles to The Mel Robbins Podcast.

    11. SW

      It's great to be here, Mel.

    12. MR

      I mean, it's incredible to have you here, so thank you for taking the time out to teach us about our skin and what our skin is trying to tell us about our health. Could you start by speaking to me and the person who's here with us about what could change about our life or our health or how we feel if we take to heart everything that you're about to teach us about our skin?

    13. SW

      Your skin is more than a beauty scorecard. It is actually information. It's a two-way conduit between the outside world and the internal systemic health that you experience. Your skin is your check engine light. It reflects your overall health. If something's starting to go wrong in your body, it can oftentimes show up on the skin as different signs. So, pay attention to the clues that it's giving you. It's a great way to influence your overall health in those distant organs too. That's the part that's key to take away, is that you have the power to influence your health. That starts at the level of your skin.

    14. MR

      That's fascinating, that we can look at our skin not as a beauty scorecard,

  2. 2:24 – 10:48

    What Your Skin Reveals About Your Overall Health

    1. MR

      because I think so many of us, particularly when you're upper in age like me-

    2. SW

      Yeah

    3. MR

      ... like 57, I start to look at all the things that I don't like what it looks like. But I don't even know how to look at my skin and see it as an engine check light that might be indicating something else that's a deeper issue.

    4. SW

      Exactly, and it could be really small signs. It's the all of a sudden moment that a lot of people describe to me. They say, "All of a sudden, I see this change in my skin. All of a sudden, this brown spot's popped up. All of a sudden, this fine line is over here. This redness is now, I'm flu- my skin is flushing."

    5. MR

      Yes.

    6. SW

      Right? It's these all-of-a-sudden moments have actually been brewing for months on end. So, the conversation's actually been started long time ago, and when you see that all-of-a-sudden spot, what's happening on the skin is really a dashboard and reflection of what's happening at your overall health. So, this is not vanity. This is actually a reflection of your health.

    7. MR

      Okay. That's really cool, because I probably am like most people that walk into your office, or walk into a dermatologist, and you're like, "I have this thing under my nose."

    8. SW

      Yeah.

    9. MR

      "Or I have this thing on my face, or my skin is suddenly this way, or this is happening and it's now a problem."

    10. SW

      Mm-hmm.

    11. MR

      And the first thing that you said is, "Hold on. The thing that suddenly appears can reveal hidden issues underneath that started a while ago."

    12. SW

      A lot of times, patients walk into my office and within the first five minutes, they're saying something like, "I'm really sorry to be talking about this. I know this is vanity. I have this concern." But that's not true. I immediately shift the conversation and say, "Skincare is healthcare. I want you to be concerned about changes in your skin, because the structure that it's showing and changing actually is a reflection of function that's happening underneath." And that's a very important conversation, because it affects patients' quality of life.

    13. MR

      I would love to hear, Dr. Wyle, what your skin reveals about what's happening in your body, and what changes may be early warning signs that something deeper is going on.

    14. SW

      It can tell you about autoimmune dysfunction. It can tell you about inflammation happening underneath. It can give you clues to disease processes like kidney disease, diabetes, chronic liver function, dysfunction. All of that can present on your skin. Psoriasis is a really good example. So, when patients have moderate to severe psoriasis, oftentimes they're at a higher risk for heart failure. There was one study that showed that if you have severe psoriasis, you're at about sixfold increased risk to your 10-year heart disease and heart event risk. This includes heart failure, heart attacks, and stroke.

    15. MR

      Got it. Okay. Why is skin health and the optimized function of your skin so important for your overall health, Dr. Wyles?

    16. SW

      So your skin is your largest living organ, and it's your largest regenerative organ. So it really, every 30 days you're getting a new layer of skin, and it has this incredible power of influencing health because if you think about it, it's our way to the outside world.

    17. MR

      Wow. All right.

    18. SW

      Yeah

    19. MR

      Well, show us what skin function means. What does your skin do?

    20. SW

      Okay, so the skin does over seven to eight different types of functions. We love to study this in our lab, so we study skin repair and wound healing. So every, a little kid who gets a cut or a scrape needs a Band-Aid, they have a boo-boo. I have two little kids of my own. And so the repair idea is that your skin naturally heals, and it, it allows you to regenerate that skin every 30 days, like we talked about, but this repair slows with age. So you heal much faster when you're younger than with older age. The other function is secretion and absorption. The skin is an active secretor. You, your skin is either oily or dry. It creates oils. It creates sweat. It absorbs topical things. So this is how we apply medications to your skin through your skin. Sensation is key. This is how we sense and perceive the world. This is how we connect, love, touch. It's all through the skin. It is also how you know when you have a paper cut, right? So when you have a paper cut, you don't know how much your skin's a good sensor till you do. Barrier defense. This is really what the skin is known for. Keeps the outside out, right? The outside world exposes us to UV pollution, particulate matter, hard chemicals, so the skin really keeps a lot of that out, and that's important when you think about barrier function. And then vitamin D synthesis. People don't talk about this enough, but vitamin D is this incredible hormone that supports our bone health, that supports our brain health, and that starts at the level of the skin. It's a conversation that your skin has with UV, and we allow that to make healthy vitamin D to support our bone and overall health. Immune surveillance, so the skin has its own microbiome, lots of friendly microbes that live on the skin, but we also monitor the skin to make sure that no one bacteria or microbe over-exaggerates or proliferates. So it really helps to keep that down. Your skin actually has its own immune system, so the localized immune system that's outside the blood immune system. And then finally, like we didn't have enough different functions to do, it's a great thermoregulator. So what does that mean? This allows us to regulate temperature, Mel. So this is how we can cool the body and be perceptive to the outside world. Evolution has really prioritized how the skin and the fat underneath it play a big role in thermoregulation.

    21. MR

      Okay, so if our skin is doing all this cool stuff, and it's part of the overall function and health, and there's this two-way relationship between what's happening on the surface and what gets communicated to your deeper health inside your body and what your inside body is connecting to the surface of your skin, and you've already taught us that if something's suddenly appearing, we gotta go back at least three months and try to understand what's been happening because this might be a signal. What is happening under the surface of the skin, Dr. Wyles, as we age?

    22. SW

      Because the skin is this beautiful living organ, I want you to think about its influence from the outside in and the inside out. So the aging process within the skin is a two-way influence. So the outside in, we're having stressors from the environment, which we collectively call the exposome. So this is UV light, the pollution, particulate matter, the ozone, smoking. All of that influences the, the skin from the outside and aging process. The inside out signaling is just as important. So these signals look like metab- metabolism, so your metabolic changes. This also looks like your hormonal changes, your genetics. So it's that two-way conversation that really drives the surface and that, that colliding of the worlds that drives the surface changes.

    23. MR

      You have two studies that you're excited about when it comes to the aging of your skin.

    24. SW

      Yes. In research studies, we're finding that how you look, also known as your perceived age, can influence a lot of downstream health risk factors. There was a recent study that showed that when you look at cancer patients, they had a study looking at over 6,000 patients and did an AI facial image analysis and found that the patient's cancer survival and prognosis correlated with how they look. Their perceived age and those changes that they're seeing at the level of the skin actually has a biological influence, and it's showing cues that could be affecting their cancer prognosis and how they're surviving through the stage.

    25. MR

      This is [beep] fascinating.

    26. SW

      So there's a great Danish twin, twin study where they looked at twins and saw how their perceived age impacted their overall health. And the older of the twins actually had more changes that are declining, um, poor cognitive health, poor physical function, um, and just that perceived age look of how someone shows up actually correlates with poor survival, shorter telomere length, and shorter telomere function, higher risk of heart disease as well. So these are cues that are sh- telling us that the skin is more than vanity. It's not necessarily that structural change, but it's the underlying function that could also be reflecting through that structure.

    27. MR

      So if your skin is aging quicker-

    28. SW

      Mm-hmm

    29. MR

      ... and you're losing the structural function that your skin is supposed to be performing, all those different things you just said, it puts you at greater risk for other things.

  3. 10:48 – 18:07

    How Your Skin Ages

    1. SW

      Exactly.

    2. MR

      How do I actually know how my skin is aging, if it's doing a good job, if it's, like, really not aging well?

    3. SW

      So when patients come to see me, we do a full facial exam and a body skin exam, and we start to look for these key signs on the skin. Now we have this technology that can actually use an AI-integrated system to look at your facial image, and it can do a facial scan to give you a predictive analysis of the different parts that age over time. Are you interested in getting one of these facial scans, Mel?

    4. MR

      Well, I'm actually nervous. I saw the team setting up some piece of equipment out there, and so I kind of knew this was coming, and I'm dreading it because I'm afraid that all those decades in the '70s and '80s when I was slathering on oil and trying to burn myself are gonna come back to haunt me. And, yes, I'm gonna do this [laughs] even though I'm nervous, and I will narrate this. So if you're listening, we are gonna take you out of the studio. We're gonna walk into our offices here in Boston. If you're watching this on video, on YouTube right now, you're about to see the behind the scenes, because they've got this thing set up in the middle of a busy production day, and so we're just gonna take you right along with us. I love it when we get out of the studio, so let's go.

    5. SW

      Let's do it.

    6. MR

      I'm a little nervous. Okay, this machine actually looks like one of those foil things that my, uh, elementary school best friend, Jodi Bricken, and I would hold up, oil ourselves up, and then try to get sunburnt in the Michigan sun.

    7. SW

      This is actually a very [laughs] advanced technology that does look very similar to that, but it's going to allow us to capture all different angles and mirrors, and there's flashing lights in here to look at your skin.

    8. MR

      Do I leave my glasses on?

    9. SW

      So you can take your glasses off.

    10. MR

      Okay.

    11. SW

      This is a curved camera. And I would like you to look right here in this middle right here.

    12. MR

      Oh, just like I do at the airport.

    13. SW

      Just-

    14. MR

      Here we go

    15. SW

      ... like that. You're gonna see some flashing lights. Okay. And it's processing, so we did good. Let's give that a few moments here, and you can come back here with me, Mel. Okay, let's go through this report. So here the higher the number is really looking at y- a percentile, right?

    16. MR

      Okay.

    17. SW

      So you, 100% is what you want to get on the report card.

    18. MR

      So let me just show, tell the person listening, they're measuring spots, wrinkles, the texture, the pores, the UV spots, the brown spots, the red areas.

    19. SW

      Let's start-

    20. MR

      Let's go through it

    21. SW

      ... let's start with spots.

    22. MR

      So you say that when you have this you want to see a high number like 100% or 90% or 80%.

    23. SW

      Exactly.

    24. MR

      So I've got a nine, which feels like a D minus-

    25. SW

      [laughs]

    26. MR

      ... on spots.

    27. SW

      So the spots-

    28. MR

      Okay

    29. SW

      ... it's actually a combination of multiple different, so wrinkles, textures, pores. So it kind of takes multiple different textural surfaces and combines it into one. So it's measuring brown spots, it's measuring red spots, it's measuring other types of pigment changes. It's also measuring some surface level changes that you can see with pore sizes too. All right, so let's go through the next step. So this is wrinkles. So here-

    30. MR

      Oh my God, they're all on my forehead.

  4. 18:07 – 19:26

    The 5 Small Things You Can Do Right Now to Improve Your Skin

    1. MR

      "Oh, God." So for the person who's kinda like me that feels as though you really kinda screwed it up, you have slathered a bazillion products on yourself, you, uh, spent way too much time in the sun. What is the good news-

    2. SW

      Mm-hmm

    3. MR

      ... about the state of your skin now, and what is possible if we, um, apply the pillars that you're about to talk about that really support the skin span and the function of your skin?

    4. SW

      The good news is that your skin can reset. Your skin can listen to cues that's coming from your internal health, and different ways that we're activating your stress cues and managing resilience, your sleep cues and getting better hours of sleep, your diet and hydration. How do we optimize those things that you can control? Um, and if not, trying to be better, 1% better every day, um, different types of environmental stressors and topicals. So if we think about the skin span pillars, it's a interconnected system.

    5. MR

      How many pillars are there for the skin span?

    6. SW

      So there's five pillars.

    7. MR

      Okay.

    8. SW

      Yeah. So there-

    9. MR

      What are the five pillars for skin span?

    10. SW

      The five pillars of skin span are sleep, diet and hydration, movement, stress reduction or recovery from stress, and then topicals and treatments.

    11. MR

      Great.

  5. 19:26 – 28:01

    Why Sleep Is One of the Best Things You Can Do for Your Skin

    1. MR

      Okay. And we're gonna go through one by one. So you said the first one is sleep. How does sleep affect skin repair, inflammation, and the way your skin ages?

    2. SW

      The first im- important thing to think about with sleep is that your skin is on a circadian clock.

    3. MR

      Ooh.

    4. SW

      So if you were to think about your skin health and what it's doing during the daytime and nighttime hours, at daytime, it goes into defense mode. So it goes into protection from the outside world. So everything about your skin, of how it's producing oils, how water secretion, um, its barrier function. We talked about its immune surveillance capacity, barrier protection. So it's in defense mode. It's fighting against the outside world, the outside damage, UV, pollution, visible light, all of these things that are creating damage. It's protecting against that, so it's in a very active mode. And then at nighttime, it switches into offense, more like a repair, regeneration. So your skin doesn't sleep at night. It actually shifts into repair mode. And this is why sleep is critical for skin health. Because when you are sleeping is when your skin is actually regenerating and repairing the damage that could have occurred during the daytime. So if we look at some studies, there's actually been a study that's looked at good sleepers. So good sleepers had 30% better epidermal barrier recovery compared to poor sleepers. So what that means is that if you're getting about seven to nine hours of sleep and you're considered a good sleeper, you actually have better barrier resilience. You, your skin can stay hydrated for longer. Your skin can protect you from the outside environment and really allow you to function at its best. This is really interesting. So in another study with 24 middle-aged women, they look at consecutive nights of sleep lost. So for women that had two consecutive nights, that's how long it took. So two consecutive nights of three to four hours of sleep disrupts your skin barrier. So overall, we saw that their hydration went down, their water loss went down, meaning that you're losing more water through your barrier. So that was a statistical significant change. So with just two consecutive nights, you can really shift your skin's hydration and barrier capacity.

    5. MR

      Dr. Wyles, this is so fascinating, and it also explains why so many of the creams you see market it as repair. But I've never heard anybody say that your skin has two modes, protection mode during the day and repair mode at night.

    6. SW

      So there are signals that are, during the morning, that your genes are sending out that's like, "Turn on defense mode."

    7. MR

      Ah.

    8. SW

      And then the signals that send on at night that's like, "Turn on protection."

    9. MR

      Okay. Hold on. Let me just see if I just got something. I love it when we're having a conversation and you start to feel smart. Don't you love that as you're listening and watching, that by just being with Dr. Wyles, you feel smarter? So can I give something back to you? And I wanna see, if you're listening or watching, if you're starting to get this, too. So Dr. Wyles, what I am learning is that sleep impacts how your skin ages and functions and what it looks like because your skin has two modes, and it's driven by the circadian rhythm. And if you're up during the day and you're on, like, we're on the, the offense mode, right?

    10. SW

      Yep.

    11. MR

      That's during the day.

    12. SW

      During the day, you're defense.

    13. MR

      Okay. So if I'm up during the day and I'm on defense, I, my skin has gotta be protecting me from the world and the UV-

    14. SW

      Yeah

    15. MR

      ... and all these, uh, people running around, and oh my God, pollutants, and-

    16. SW

      Yeah

    17. MR

      ... you know, oh my God. And now of course it's dehydrated. It's working very hard. Then I go to lay my head down on the pillow with the circadian rhythm, and my skin is like, "Oh my God. We can rest. I can go on offense mode, meaning I can take a proactive step forward-

    18. SW

      That's right

    19. MR

      ... while this, you know, you know what is sleeping."

    20. SW

      Isn't that beautiful?

    21. MR

      "And, and I can repair, and I can shed, and I can take care of myself so that when she wakes up again, we can go back into it." And if you are not getting good sleep, your skin cannot go into that mode. And if you're... Like, now I'm thinking about why I looked terrible when I had babies.

    22. SW

      Mm-hmm.

    23. MR

      Why I started to look like I had been sleeping under, like, a dumpster or, like, out camping when I got perimenopause, because my sleep was interrupted every two to three hours.

    24. SW

      Mm-hmm.

    25. MR

      So if your sleep is interrupted every few hours and you're not getting a good night's sleep, your sleep pattern is confusing your skin.

    26. SW

      Mm-hmm.

    27. MR

      And so it's probably jumping, "Wait, are we in offense? Are we in defense?"

    28. SW

      Mm-hmm.

    29. MR

      "Is she awake? Is she up?"

    30. SW

      That's right.

  6. 28:01 – 33:31

    What to Eat for Healthier, Younger-Looking Skin

    1. MR

      So the second pillar that you mentioned was diet and hydration, and I'm realizing right now that I've been hydrating this entire conversation with an iced coffee-

    2. SW

      [laughs]

    3. MR

      ... and I should switch it for water. [laughs] But let's start with diet while I switch the coffee off the table and put water on. What does your research, Dr. Wyles, say about nutrition slowing or improving the way your skin ages?

    4. SW

      So the data around skin and diet is quite good. So it's, uh, this skin-gut axis of how your skin and your gut health are interconnected and related. And a lot of this is known if we look at acne patients, too. So there's a randomized 12-week trial for acne patients, and they put them on a low glycemic index diet. This means low sugar, low carbohydrate diet. And they found that these patients had a 23% improvement in their acne flares just by switching their diet. So it's, it-

    5. MR

      Wait. Hold on.

    6. SW

      Mm-hmm.

    7. MR

      Say that again? So, 'cause, 'cause the person who is having an acne flare-up-

    8. SW

      Mm-hmm

    9. MR

      ... and does this count for all kinds of acne? Stress acne, cis- what's it called? S- s-

    10. SW

      Cystic acne

    11. MR

      ... cystic acne? Like, all of it?

    12. SW

      Yes, all of it.

    13. MR

      So if you're having an acne flare-up, what was that research?

    14. SW

      When you have a low glycemic, so low sugar, low carb diet-

    15. MR

      And what are some of the low sugar, low carb diets that would be out in the world of people like, "Oh, that kind of diet"?

    16. SW

      So vegetables, more fiber rich, uh, products, like beans and, um, dark green leafy vegetables, um-

    17. MR

      More whole foods

    18. SW

      ... more whole foods, plant-based.

    19. MR

      More, more, more protein, plant-based, that kind of stuff.

    20. SW

      Exactly.

    21. MR

      Gotcha.

    22. SW

      Versus a high sugar index. Even fruit can sometimes be in that category.

    23. MR

      Okay. Wow.

    24. SW

      Mm-hmm. So that really shifts the, and reduces the acne flares.

    25. MR

      Remind me what glycation is.

    26. SW

      So glycation is how sugars stick together. So it's sticky sugars-

    27. MR

      Okay

    28. SW

      ... that happen in your skin, and the sugar sticks to something called collagen and elastin that's present in your skin.

    29. MR

      Okay.

    30. SW

      So then it stays there for a long time and influence and break down your skin matrix.

  7. 33:31 – 38:12

    The Glowing Skin Smoothie

    1. SW

      Yeah, yeah.

    2. MR

      Um, I've heard you have a secret skin smoothie. I want you to talk to me about this smoothie and the benefits of putting specific ingredients, Dr. Wyles, in your smoothie. I see beets, I see apples, I see carrots. I don't know what the heck is in that thing.

    3. SW

      Turmeric.

    4. MR

      Oh, it's orange.

    5. SW

      Mm-hmm.

    6. MR

      Turmeric.

    7. SW

      Mm-hmm.

    8. MR

      And some seedy looking things.

    9. SW

      Mm-hmm.

    10. MR

      Okay, and you're gonna explain all of this.

    11. SW

      So this is something really special that I shared with my grandmother. I think there's a lot of wisdom that we can learn from our mothers and grandmothers, and every morning my grandmother would say, "Don't forget your ABCs." Now, I grew up in South India, in Chennai, and, um, we called our thathi. So Thathi would say, "Okay, don't forget your ABCs," and what she meant was your apples, beets and carrots.

    12. MR

      Oh, ABC. Apples-

    13. SW

      ABCs

    14. MR

      ... beet, carrot.

    15. SW

      When I had kids, this is what I turned to. I said, "I don't know what to feed them, so let me take these and stick them in an Instant Pot." So what ended up being my grandmother's recipe ended up being a convenience factor for me. This is what my kids ate almost every day. [laughs]

    16. MR

      Okay, so hold on. By Instant Pot, you mean like a Crockpot?

    17. SW

      A Crockpot.

    18. MR

      Okay, so like any slow cooker. So we're talking you're got a busy life, we don't have time to do a cooking show.

    19. SW

      Right.

    20. MR

      And neither do you in your life, so you're gonna take Instant Pot, Crockpot, whatever you want, you're gonna chuck in carrots, apples and beets?

    21. SW

      Carrots, apples and beets.

    22. MR

      And do you leave the skin on?

    23. SW

      I do. And the, and, and I'll tell you why. There's research behind this.

    24. MR

      Talk to me.

    25. SW

      In the skin of an apple-

    26. MR

      Uh-huh

    27. SW

      ... my, um, in-laws are apple farmers, so I'm really passionate about apples.

    28. MR

      No way.

    29. SW

      They are. And the reason why you keep the apple peel on is because it's got quercetin in it, and quercetin lives on apple skin, which is a type of flavonoid, which is a type of anti-senolytic. So when we think about, you know, these senescent or zombie cells, well, how do we target them? How do you get rid of them? There are natural products in fruits and vegetables that exist that can target and reduce those presence of those cells. This is a really cool fact, Mel. So with flaxseed and chia seed, you're getting alpha-linolenic acid and you're also getting fiber. And I love this fact, um, because fiber is something that we know that we need to get, uh, for healthy skin. We just talked about reducing your glycemic index. In addition to that, did you know that chia seeds also have calcium in it?

    30. MR

      They do?

  8. 38:12 – 39:34

    How Much Water Do You Really Need for Healthy Skin?

    1. SW

      Mm-hmm. Okay.

    2. MR

      As someone who has two centers at the Mayo Clinic, Dr. Wyles, how much water do you need to drink in order to have healthier skin?

    3. SW

      Yeah, so when you think about hydrating your skin, there's two ways. There's a little bit of a myth that goes around, okay? So the myth around hydrating your skin is that people think drinking water is enough to hydrate their skin barrier.

    4. MR

      It's not?

    5. SW

      But it's not.

    6. MR

      It's not?

    7. SW

      You actually need to apply moisturizer. So a lot of the studies are showing that only a portion of water that you drink shows up on the skin, right? So y- you have to think about the hydration needs can really shift. It can, uh, be affected by your climate, the humidity, and a lot of different things. So how much water do you need to drink? For women, it's about two liters a day, uh, 11 to 12 cups.

    8. MR

      So I have a large wide-mouth mason jar right here, and I typically drink two of these a day, and one of i- this is, like, four cups each.

    9. SW

      Perfect. So about eight cups is good enough, but if you can try to get to 10 or 12 cups, that's better. Especially if you're in perimenopause and menopause, your baseline water loss has increased, and our levels of stress as women have increased. [laughs] So, so you're just losing more water every day just by-

    10. MR

      We're sweating it out, ladies

    11. SW

      ... [laughs] So just aiming for about 10 cups is, is, is key for women. And for men it's, uh, two additional cups more than that, so 12 to 13.

    12. MR

      Wow.

    13. SW

      Mm-hmm.

  9. 39:34 – 43:16

    How to Choose a Moisturizer That Works

    1. MR

      Now, you also said that it's the inside and the outside.

    2. SW

      Mm-hmm.

    3. MR

      So what am I doing on the outside to hydrate my skin? Because I know people have told me before, my own dermatologists, maybe even other medical experts, but can you remind us what is the thing we're looking for that is hydrating when you put it on your skin?

    4. SW

      So the skin needs humectants. Humectants are ingredients that pull water in.

    5. MR

      Oh.

    6. SW

      So these are gonna be like glycerin, ceramides. These are gonna look like, um, colloidal oatmeal can reduce inflammation and calm the skin as w-

    7. MR

      Oatmeal is hydrating?

    8. SW

      Oatmeal is. It's finely ground. It's called colloidal oatmeal. Um, this is actually FDA approved. So if you go in a lot of the brands, uh, for eczemas-

    9. MR

      Uh-huh

    10. SW

      ... moisturizers and lotions, it'll say that it has an FDA seal on it.

    11. MR

      Huh.

    12. SW

      And it says, "National Eczema Foundation Approved for Eczema Skin." So broken skin can get a lot of benefits from colloidal oatmeal because it has the ingredients to calm the skin down. Um, the other, uh, humectant, AKA something, an ingredient that pulls water in, is beta-glucans. So beta-glucans is another active that you can look for in the ingredient list. So these are gonna pull water in. You also wanna look for moisturizers that are tub lotions that you can scoop out versus pump lotions.

    13. MR

      Why?

    14. SW

      Because tub lotions are thicker, and y- and they hold more moisture in there versus pump lotion, to get it out of the pump, they actually have to add water, which is counterintuitive. There's more liquid in there. It rubs on nicely, but it also evaporates and loses the barrier faster.

    15. MR

      I wouldn't have thought that pumping it to get it out through that little thing makes it less concentrated.

    16. SW

      It's a thinner lotion.

    17. MR

      Oh.

    18. SW

      The tub lotions are thicker.

    19. MR

      So, Dr. Wyles.

    20. SW

      Mm-hmm.

    21. MR

      I just had this image of you either at the grocery store, or Target, or CVS, or somewhere else, and you've got your two kids, and it's a Saturday, and you're pushing your cart, and then you see somebody like me just staring at the aisles, and I'm reaching for something that you know is a c- giant waste. D- is it hard for you to not walk up to people-

    22. SW

      Mel

    23. MR

      ... and be like, "Da- I d- I d- d- just buy that one down there." [laughs]

    24. SW

      I have this Target moment all the time. So whenever I'm in Target, I am so tempted by people looking at products and just seeing what ingredients there are. I just wanna go up to them and be like, "Hey, I've been there. Um, can I just help you? And I just wanna help you pick out..." Especially if they're in the baby aisle, and they're, like, choosing between different products. How do I, what do I choose, which ingredients? I just wanna go up and be like, "H- try this, and this has, you know, this is more good for sensitive skin," or, "This is better for this type of eczema-prone skin." Just, just to help them out, you know? And it's so tempting, but I have to resist myself. And this is a key conversation. People are overwhelmed with what's out there in our grocery stores and over-the-counter, which is a good thing because it's accessible.

    25. MR

      Hmm.

    26. SW

      But it also, the choices make it seem like they're s- insurmountable, and it's harder decision-making.

    27. MR

      So do you s- should you stay away from fragrance given that your s- the purpose of the moisturizer is really- To hydrate your skin

    28. SW

      Yeah, so fragrance-free, unscented. You wanna look for both of those words.

    29. MR

      Oh, okay, this is a dumb question. You ready? Those are different?

    30. SW

      Those are different. And y- this is gonna shock you. Unscented can mean that they're actually adding fragrance in to mask the scent away.

  10. 43:16 – 46:57

    How Exercise Helps Your Skin Stay Healthy as You Age

    1. SW

      Mm-hmm.

    2. MR

      Dr. Wyles, what does regular exercise and movement do for your skin, and how can movement help your skin age better?

    3. SW

      Um, I have some really cool studies here.

    4. MR

      Oh my God, I can't wait

    5. SW

      And I'm, like, so excited. Um, okay. So your skin responds to exercise, so there are some really great human data that supports this. So in a small randomized study with older adults, they found that the skin healed faster, in an average of 10 days faster, in the group that exercised compared to the group that didn't exercise.

    6. MR

      Really?

    7. SW

      It impacts wound healing. Exercise actually secretes out positive signals for your body to reduce inflammation, to help metabolic signaling, metabolic health. So one of the things that the body releases, they're called exosomes or extracellular vesicles. They're, they're really fun. They're like text messages that your body sends to each other and, and send signals of benefit, but they can also send signals of harm, but depending on where it's coming from. With exercise, this can actually be a positive cue to send circulating beneficial exosomes all around, to all distant organs, including the skin, and these messages can help that repair process that you're seeing.

    8. MR

      I wanna just remind you, as you're listening and watching, that Dr. Wyles runs two centers at the Mayo Clinic, one of which is researching and focuses on wounds.

    9. SW

      That's right. I love my research lab. Uh, we have a, the Regenerative Dermatology and Skin Longevity Lab. We're part of the Department of Dermatology. Um, and it's a, it's a good team.

    10. MR

      So is there something about the circulation that helps, too?

    11. SW

      So definitely the circulation 'cause it, the, those exosomes that are coming through are coming through the circulation. So they help create better blood flow, better messages that are going all around, so just overall, this idea, Mel, is getting back to homeostasis. I'm gonna, I'm gonna break this word down 'cause it's one of my favorite words.

    12. MR

      Homeostasis.

    13. SW

      Homeostasis.

    14. MR

      Okay.

    15. SW

      Homeostasis means reestablishing balance, and I, we love studying regenerative medicine in our lab, and the skin being the largest regenerative organ, it constantly is going through the u- the leverage of enduring stress and breaking down and being resilient to stress. There was another study, a 16-week study, in 56 middle-aged women. They looked at cardio versus resistance training, and what they found was, in these patients, they had better skin elasticity, and the upper layer of their skin, which it holds the collagen and elastin, improved. This was-

    16. MR

      Which kind of training?

    17. SW

      This is, this is with weightlifting and weight strength training.

    18. MR

      Okay. I'm so glad you said that because every medical doctor that has come on in every single field has said, for women in particular-

    19. SW

      Mm-hmm

    20. MR

      ... strength training, resistance training, non-negotiable for every aspect of your health. So if you were about to say cardio-

    21. SW

      It's a combination, but resistance training plays the bigger role-

    22. MR

      Okay

    23. SW

      ... for sure.

    24. MR

      Why?

    25. SW

      Because the skin and muscle are super interconnected. You know, we, we have a constant communication, so those strength training, those signals actually transcend to the skin. And this is actually why I tell my patients who are on GLP-1 medications, who have that weight loss that they're experiencing, that strength training becomes a very important part of their conversation because it can help tighten their skin elasticity.

    26. MR

      Well, that makes sense 'cause as you're teaching us, the skin is the largest organ. It's a living organ. It's sending information in. It's receiving information out, and the more you're pumping up your muscles, the more it must plump up and pump and tighten up your skin.

    27. SW

      Mm-hmm.

  11. 46:57 – 51:36

    What Stress Is Doing to Your Skin

    1. MR

      The fourth pillar is stress. How does chronic stress impact your skin?

    2. SW

      So let's talk about cortisol. This is the stress hormone. Um, and we've all heard about it. Um, cortisol receptors are part of your skin, and this is really fascinating why they're part of your skin. So your skin has this neuroendocrine system, fancy way of saying it's part of the fight or flight mechanism, right? And it's evolutionarily there because your skin plays an active role in that defense, right? You're going out into the world. It's, it's receiving all of the external damage from the outside world first, so it has to be frontline defense mode and reducing the inflammation. It has to be part of that fight and flight response, so there are natural cortisol receptors that are part of your skin. And it's partly there also because it's this adaptive response. So because it encounters stress, it can create adaptive signals to defray the stress, too. It's helping you combat stress. Why is this important? So this means that when you're in stressful situations, your skin knows it, and it perceives it. So if you're on a airplane in high altitude situations, your skin is stressed.

    3. MR

      Is that why I'm puffy on a plane?

    4. SW

      You can be. Yes.

    5. MR

      Wow.

    6. SW

      Yeah.

    7. MR

      Okay.

    8. SW

      UV, UV damage, that stresses out your skin. This is an interesting study. Did you know that the stress of going through a divorce can impact your skin barrier recovery? They did this study, and they found that, um, in 28 healthy women aged between 21 and 45 years old, the process of marital separation showed up on their skin. They had worse total epidermal water loss, meaning their skin lost more water. And when they took the tape strip, which is the top layer of the skin, and evaluated it, that barrier strength was not affected, but your ability to recover from injury was affected.

    9. MR

      Oh, that doesn't surprise me-

    10. SW

      Mm-hmm

    11. MR

      ... 'cause that's extraordinarily stressful.

    12. SW

      Very stressful.

    13. MR

      Does stress lead to hair loss, Dr. Wyles?

    14. SW

      Yes, and stress can show up in the hair in a different way. So hair grows in different cycles. So we grow, rest, shed, grow, rest, shed. And at any given time, our hairs are always cycling between them, and we actually have normal shedding seasons. So in the spring and the fall, you're supposed to shed a little bit more than the other seasons. So with these different cycles, there, stressors can actually shift the hair from these growth phase or resting phase into the shedding phase.

    15. MR

      Okay.

    16. SW

      And this can show up about three or four months after that stressful event. So say you've kind of had, um, lot, you know, loss of a family member, loss of a pet, a surgery, an illness, um, and a very stressful w- work situation. Whatever that is that occurred, it'll take about three or four months to re- be reflected on your skin and your hair. So it's a, it's a important clue to pay attention to, but it is a reversible clue.

    17. MR

      First of all, Dr. Wyles, how much shedding of hair? 'Cause there are those periods where I've looked down on the floor of the shower or I have, you know, washed my hair and I run my fingers through my, and I'm like, "What is this?" Like, this is like a wig in my hands. And then I start to get worried, like how much is too much?

    18. SW

      So everybody experiences a natural, normal shed every time you wash your hair.

    19. MR

      Okay.

    20. SW

      Every time you wash your hair, it's in the hundreds. It seems like a lot, but there's a lot of different structures within hair.

    21. MR

      What should you do? I-

    22. SW

      Mm-hmm

    23. MR

      ... sleep better, eat better. Is there something to do?

    24. SW

      I am a big fan of pumpkin seed oil.

    25. MR

      What?

    26. SW

      Yes. I'll tell you about this. This is a, there's actually studies around pumpkin seed oil. It's a supplement. So, uh, in a study where they supplemented 400 milligrams of pumpkin seed oil, and they followed, um, these men for about 24 weeks, and these were men that are having male pattern baldness, and they had shown that it actually can shift the androgens that influence hair loss and allow the pathways. So there's actually an, an analog that comes from pumpkin seed oil that can help reduce those types of signals and can support a healthier hair follicle environment.

    27. MR

      No kidding.

    28. SW

      Mm-hmm.

    29. MR

      Wow. I'm putting that in the cart-

    30. SW

      Mm-hmm

  12. 51:36 – 52:42

    What Your Nails Say About Your Health

    1. MR

      Okay, so let's talk about nails.

    2. SW

      Yes.

    3. MR

      Let's say your nails are breaking or you got ridges or white spots. What does that tell you?

    4. SW

      So your nails can reflect nutrition deficiency there, too, and it can have aging patterns. So ri- ridges, for instance, those can be just seen with normal aging, and it's, it's, it's okay to see those changes. But you wanna pay attention because pigment can also show up on your nails. So when you see pigment, both white patches and brown or black patches.

    5. MR

      Okay.

    6. SW

      When you have pigment changes, you need to go see a dermatologist, and this is because, especially when it's dark brown, you wanna be evaluated to make sure it's not a melanoma.

    7. MR

      Okay.

    8. SW

      Now, pigment changes can also happen during pregnancy and postpartum, or if you're darker skin types, you can also see changes in your nails. But really paying attention to those check engine light that we talked about, they can be check engine light on your nails, too, and they can give you clues even for liver dysfunction. Cirrhosis has a telltale sign that we look for on the nails. Um, fungal infections can also present as yellowing discoloration on the nails. So there's different aspects that your nails can provide, uh, for clues of what's

  13. 52:42 – 57:39

    Truth About Peptides: What Works and What's Hype

    1. SW

      going on on the inside.

    2. MR

      The fifth and final pillar that you mentioned is topicals and treatments. And Dr. Wyles, I would love to have you unpack something I see everywhere and I do not understand, and that is the word peptides.

    3. SW

      So peptides are short amino acids. They're like little Legos. So you can put them together to build a bigger protein. So when you think about it, you take these pieces, and it can function into a different type of protein. And we're familiar with GLP-1 medications. These are part of the peptide family. But think about these peptides as keys also, that can open up a door that could mean nothing or m- very limited, or it can open a very powerful door, as the one that has opened with GLP-1s and weight loss medication.

    4. MR

      Okay, so this is something that acts like a key to unlock something that is inside your body.

    5. SW

      Body.

    6. MR

      Okay. How do I know what key is gonna work and whether or not something is safe or it's complete marketing BS? Because it seems like that word is slapped on everything right now.

    7. SW

      Yes. So peptides have really gained a lot of traction right now, um, with the longevity movement and the, um, wellness space as well. You know, you have to be v- really cautious. It, it can be applied topically, or it can be applied injectables. Um, peptides currently are sourced very differently, and they're not FDA regulated at this point, although some of them can be FDA regulated and medications-

    8. MR

      Like the GLP-1

    9. SW

      ... like the GLP-1 medications.

    10. MR

      But the vast 99.9% of things, no testing, no FDA regulation, proceed with caution. Is that what you're saying?

    11. SW

      Proceed with caution, but I'm hopeful. I'm actually a fan of peptides being tested in the positive way. So right now, the FDA's creating, um, new shifts with 503A compounding pharmacies and what are gonna be bulk compounded. This is actually giving people a safer way to access peptides, but the key is to t- take that and create evidence-based clinical trials.

    12. MR

      When it comes to peptides that are getting injected, unless it's something like a GLP-1 that has been clinically tested- Dr. Wyles, is that safe?

    13. SW

      So outside of that, you're just creating an experiment on your own. You're trying to f- you're becoming... The body is a pin cushion. They're applying different types of combinations of peptides. You're working with your physician to figure out what's the right version for you. Anecdotally, we're hearing benefit, but we can't generalize that and provide guidelines without having clinical trials.

    14. MR

      Gotcha. So you're basically running an experiment on yourself.

    15. SW

      Correct.

    16. MR

      Um, what about topicals? Are there topical ingredients that are, quote, "peptides" that you're excited about even if they don't have the FDA approval yet?

    17. SW

      I'm a big fan of the topical copper peptides. There is evidence behind this. Um, there's data that's showing that it can actually help the dermal epidermal junction and create collagen, but it's really... And, and it can be delivered topically as well. So a lot of times, I wanna do a myth busted right now. Okay? I wanna talk about this glow stack peptide. So right now, a lot of people are really excited about, and it's become really popular, Mel, this glow stack. So this glow stack is BPC 157 peptide, TB500 peptide, and the GHK copper peptide, and it's an injectable combination.

    18. MR

      For your skin?

    19. SW

      For your skin. That's what they say. If you inject this stack combination, then that creates skin glow.

    20. MR

      Okay.

    21. SW

      But from a research perspective, the first two peptides, while I'm excited about [laughs] those for different reasons, they don't have any skin-generating data. And the GHK copper works really well as a topical, so we don't need to go the injectable route. Because if they are injecting it, I'd be worried about copper levels, and at what point do we need to be doing additional testing. So that stack is something that I don't recommend. Instead, I say use the topical copper peptides.

    22. MR

      Um, what non-peptide topicals do you recommend?

    23. SW

      So I like to think about your daytime and nighttime skincare differently.

    24. MR

      Okay.

    25. SW

      Because we talked about circadian rhythm s- shift.

    26. MR

      Yes

    27. SW

      So-

    28. MR

      And in the daytime, you're on defense-

    29. SW

      Mm-hmm

    30. MR

      ... protecting yourself against the world.

  14. 57:39 – 1:04:42

    Sunscreen: What You Need to Know to Protect Your Skin

    1. SW

      sunscreen.

    2. MR

      Dr. Wyles, teach us about sunscreen.

    3. SW

      All right, Mel. Sunscreen is one of the best things you could be doing for your skin. It protects your skin barrier from the outside UV exposure, so I want you to be using a broad spectrum SPF 30 or greater and reapplying the sunscreen regularly. But do you wanna be put to a test?

    4. MR

      Yes.

    5. SW

      Okay.

    6. MR

      Uh-oh, she's coming over, everybody. She's got a tray. I'm gonna narrate this for you if you're not watching on YouTube. Okay, you have a tray that has five different things on it. Tell us what's on there.

    7. SW

      So I've got a tray here with different types of sunscreen. In the bottom-

    8. MR

      Yep

    9. SW

      ... so I have a mineral sunscreen-

    10. MR

      Yep

    11. SW

      ... I have a chemical sunscreen, and I have a tinted sunscreen. So three, these are three different versions that you can get at the drugstore. And then at the top I have beef tallow and I have coconut oil. So a lot of times we're seeing beef tallow and coconut oil within our sunscreen products. So we're gonna test all of these and see against a UV camera-

    12. MR

      Okay

    13. SW

      ... how well these actually protect you from UV rays.

    14. MR

      Okay, what is real and what is BS? Here we go.

    15. SW

      All right, Mel. I'm gonna apply these-

    16. MR

      Okay

    17. SW

      ... forearm here, and we're gonna start from the top, which is we're gonna do just the sunscreen, so we'll do mineral sunscreen over here.

    18. MR

      Okay.

    19. SW

      Then I'm going to go into a chemical-

    20. MR

      And she's using a different finger.

    21. SW

      I am.

    22. MR

      Because this is very much a research project. Now, this one's rubbing in. This is more like moisturizer.

    23. SW

      Exactly.

    24. MR

      You can't even see it.

    25. SW

      So chemical sunscreens, very nice.

    26. MR

      Okay. What is the chemical in a sunscreen that blocks UV ray?

    27. SW

      So there's a lot of different types of chemicals. We actually just got a new chemical filter called bemetrizole, B-E-M-T.

    28. MR

      Uh-huh.

    29. SW

      This is the first sunscreen filter that's been approved in our market in over 20 years.

    30. MR

      Wow.

  15. 1:04:42 – 1:15:46

    Signs of Skin Aging: What's Normal and What You Shouldn't Ignore

    1. MR

      Um, I can't help but use this as my personal, uh, dermatology session, and I am just gonna say the one thing I can't stand. Like, I didn't think about my body that much 'cause I can't see my back, but the thing I have to stare at all the time is my face, and I really hate my jowls. Um, what is happening to the structure of your face as you age and your skin starts to hang there like a purse you don't want?

    2. SW

      So this is a normal aging process that is actually a structural change. Your skin is not the problem when it comes-

    3. MR

      Really?

    4. SW

      ... to the jowls, no.

    5. MR

      Okay.

    6. SW

      Your skin is actually just reflecting what's happening. Let me show you something with a cake-

    7. MR

      Okay

    8. SW

      ... that we can take a look at, and, and we'll talk about what's really happening.

    9. MR

      Okay, great. Um, we have our executive producer going outside. This is a fun episode because we, as you're watching, are taking you all over the place, and I'm doing my best to narrate it. But I just hate this, and so I just first wanna understand what's happening and second wanna understand do I just have to live with this? Is this, is, is this Mel Robbins version of radical acceptance? And I know it's a sign of aging, and I wanna age gracefully, and I don't wanna look 30 when I'm 70 or 80. I want to look my age, but energized and vibrant and, you know, just healthy. And my jowls make me feel like a sad, old hag.

    10. SW

      Well, Mel, I'm sitting across from you right now, and you look amazing. But really, what... Let's talk about the structural problem that's happening with jowls. Okay?

    11. MR

      Okay, and I'm gonna describe this because she has in front of her a beautiful cake. And imagine you're at a wedding and they give you a big old triangle slice of cake, and it's multi-layered. So there's, like, the, uh, red velvet on the top. Then we got the buttercream icing. Then we've got the vanilla cake, and then at the bottom we've got a chocolate fudge. And so we got, we've got these three layers with the frosting in between.

    12. SW

      And it smells really good. [laughs]

    13. MR

      Oh, God, we're gonna have to have a piece when we're done.

    14. SW

      So there's actually two other pieces to the cake layer, Mel, the disc and the platter that it's sitting on.

    15. MR

      Oh.

    16. SW

      And this has becomes important part of this analogy.

    17. MR

      Oh.

    18. SW

      So let's talk you through it. So what's happening within your skin is actually reflected on the layers of the cake. So your skin has three different layers.

    19. MR

      Okay.

    20. SW

      So you have the epidermis. This is the part that normally sheds out, and, you know, we talked about-

    21. MR

      So that's the top layer

    22. SW

      ... regenerative top layer.

    23. MR

      Okay.

    24. SW

      That's the red velvet. And then the second part is your dermis. This is where your collagen, elastin, all those matrix proteins live. This is the scaffold of your skin.

    25. MR

      Okay.

    26. SW

      And then in the bottom, this is your hypodermis, which is where the fat lives, how you regulate your temperature. This- ... disc that it's sitting on. This is the muscle. We're gonna call this the ligaments and the muscle that are-

    27. MR

      In my face.

    28. SW

      In your face.

    29. MR

      Okay.

    30. SW

      Um, and this is becomes the SMAS of your skin, if you will.

  16. 1:15:46 – 1:24:13

    You Can Build Healthier Skin

    1. MR

      So, Dr. Wyles, if the person listening takes one thing away from this extraordinary conversation, what would it be?

    2. SW

      You are serving your overall health, and by listening to the skin, it's a bidirectional conversation. It provides us clues and information of how your overall health is functioning. And by looking at the skin, we also have the power to influence our overall health. But really the conversation is that it's okay. You need to be more forgiving to your skin, which is functioning in so many different ways. And the final thing I'll leave you with is that the face gets the marketing budget, but the whole organ deserves the care, and that is healthcare.

    3. MR

      Ooh, I love that. The face gets the marketing budget of all these products, but the whole body is the healthcare.

    4. SW

      Exactly.

    5. MR

      This has been extraordinarily fascinating and empowering and fun. Dr. Wyles, what are your parting words?

    6. SW

      I'm so honored to have this conversation with you, Mel, and I have to say that to me, this was an experience that I manifested in a way. I thought in doing our research with my lab, looking at the skin and seeing the changes that it can confer for your overall health, I had this thought. I thought, "Wouldn't it be great if I shared this with just the world, and how important it is to think about your skin, and not just in a way that is being marketed to you, but really shift the conversation about how important it is for your overall health?" And literally three months later, I ran into you in an elevator, [laughs] and we made that connection, and, um, here I am. So thank you for this opportunity to talk to your viewers.

    7. MR

      You're welcome. And you know, there is something magical about this show. I really believe that. I was in an elevator. The doors opened up. You walked in. You had on the coolest outfit. You had on one of those tags. You were here for, like, some big medical conference at Harvard or something like that, and you said hello. I said hello to you. I c- I think I complimented your skirt or something, and then we started talking. We then find out that you're not even just incredibly dressed and super smart and really outgoing, you happen to be a rock star medical researcher doing unbelievable things, running two centers and this research lab. So yes, you did manifest this. Yes, it is important to say hello to people in elevators. Yes, it is important to put out in the world what you want to see and experience in the world. Because when you do, extraordinarily magical things happen. So thank you for having that intention. Thank you for being in that elevator. Thank you for doing the research that you do, and thank you for making us feel empowered and smart about how to take care of the largest organ in our body. I definitely am leaving here really excited, and I can't wait to share this with so many people in my life. And, you know, I'm excited for you. I want to thank you as well for making the time to listen to this or to watch this. And in case no one else tells you today, I wanted to be sure as your friend to tell you that I love you and I believe in you. I believe in your ability to create a better life, and health, your health, that is the basis of having a better life. And everything you learn today is gonna help you make smart decisions that will make you feel better in your own skin. All righty, I'll see you in the very next episode of Welcome You In, the moment you hit play. This segment is brought to you by Mrs. Meyer's. Now, you may think that you're ignoring the clutter around you, but your brain isn't. See, the little things in your home can affect you more than you realize. The noise, the clutter, even weird smells, all of these things can make it harder to relax or to get into creative head space. Mrs. Meyer's premium scented oil diffuser helps you keep your space calm with up to 60 days of long lasting garden inspired scent that fills your home, and you deserve that. Physical clutter creates mental clutter, and one of the fastest ways to clear your mind is to clear your space. You may be trying to ignore all the distractions and the mess around you, but your brain can't Let me give you an example. Have you ever been driving and all of a sudden you're getting close to where you need to go, but you're starting to feel lost, and you're looking for building number 103, but you can't tell, wait, is it on the left? Is it on the right? And as you're looking for the building, the music in the car, it's loud, it's playing. What do you do? Well, you just instinctively reach for the volume, and you turn the music down in order to concentrate on where you're going. But have you ever stopped to consider, do you need your ears to find building 103? No. So why do you turn the music down? Because while you think you can ignore all the distractions around you, your brain can't. Turning down the music silenced. It helps you see because your brain has less to process. It can focus. See, when you turn down the music, you're giving your brain a clean slate. The same is true with life. When you walk into your office or your bedroom or your kitchen and it's just filled with bills and dishes or laundry, of course, you're gonna feel overwhelmed. And here's what's interesting. That physical clutter becomes mental clutter that you take with you when you leave the room. There's really interesting research around this. Researchers put about 124 college students into a virtual subway station, and for some of them, the space was super clean, right? Everything was neatly organized. It was a very clean subway station. For other people in the study, the subway station was just super messy. There was trash scattered everywhere. Construction materials were all over the place. And the students spent eight minutes in that cluttery or clean physical environment. Then they took everyone and made them take a test that required them to focus and ignore all the distractions. Here's what they found. The students who had been in the cluttered environment before the test made significantly more mistakes. In other words, even when you're trying to tune out the mess around you, all of that clutter can make it harder for your brain to focus on what's right in front of you. So if you're feeling overwhelmed right now, wherever you see clutter, just take a minute and straighten it up. Maybe it's the corner of your desk where things are piled up. That always happens to me, too. Or your nightstand covered in books. It's got glasses with water in it, maybe reading glasses. The back seat of your car that's starting to look more like a garbage can. Maybe it's the chair in your bedroom that's morphed into a clothing rack. Just pick one space that makes you feel overwhelmed, and then just tackle it. And every time you pick something up, you put it where it belongs, you clean one surface, you organize your fanny pack. That's exactly what you're doing. You're turning down the music so you can focus. You're giving your mind a clean slate, and you will feel an immediate difference. You'll exhale, your shoulders will drop, your mind's gonna feel less cluttered, and that overwhelming stress, it'll start to dissipate. And that's what cleaning the mental slate is all about. It's a gift you give to yourself anytime you need it. Because the fastest way to create a little more calm in your mind is to create a little more space right in front of you. I want to say thank you again to our new sponsor, Mrs. Meyer's. I love Mrs. Meyer's. They look to the garden for inspiration because they believe the best stuff in life is simple. So do I. Mrs. Meyer's premium scented oil diffuser provides long-lasting garden-inspired scents like rainwater, lavender, peony, compassionflower, which fill your home with calm. Don't get hung up on the noise, clutter, and weird smells. Reclaim your space with Mrs. Meyer's. Find your outlet. Mrs. Meyer's plugin scented oil diffusers. All righty, and thank you for watching all the way to the end here on YouTube. And thank you for sharing this episode with the people in your life. I know you want to watch another episode, and you are gonna love this one. I'll welcome you in the moment you hit play. [upbeat music]

Episode duration: 1:24:13

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