Skip to content
OpenAIOpenAI

Building AI for better healthcare — the OpenAI Podcast Ep. 14

Healthcare systems around the world are under strain, and both patients and clinicians are feeling the impact. OpenAI's Head of Health Dr. Nate Gross and Karan Singhal, who leads Health AI Research, discuss how AI can help address the biggest challenges. They cover how OpenAI is training models to handle sensitive health questions in collaboration with physicians, and how that foundation is unlocking a new generation of tools for patients, clinicians, and healthcare systems. Chapters: 00:00:38 – Origins of Nate and Karan’s interest in AI and healthcare 00:05:01 – Strategy for building AI tools for clinicians 00:06:57 – How AI models are trained for health use cases 00:10:15 – How OpenAI is able to score well on health evals 00:14:21 – Key challenges deploying AI in healthcare 00:21:05 – Collaboration with hospitals and healthcare systems 00:23:05 – Practical everyday uses of AI health assistants 00:26:43 – Biggest “wow” moment during development 00:28:46 – Feedback from clinicians and early users

Andrew MaynehostKaran SinghalguestDr. Nate Grossguest
Mar 16, 202630mWatch on YouTube ↗

Episode Details

EPISODE INFO

Released
March 16, 2026
Duration
30m
Channel
OpenAI
Watch on YouTube
▶ Open ↗

EPISODE DESCRIPTION

Healthcare systems around the world are under strain, and both patients and clinicians are feeling the impact. OpenAI's Head of Health Dr. Nate Gross and Karan Singhal, who leads Health AI Research, discuss how AI can help address the biggest challenges. They cover how OpenAI is training models to handle sensitive health questions in collaboration with physicians, and how that foundation is unlocking a new generation of tools for patients, clinicians, and healthcare systems. Chapters: 00:00:38 – Origins of Nate and Karan’s interest in AI and healthcare 00:05:01 – Strategy for building AI tools for clinicians 00:06:57 – How AI models are trained for health use cases 00:10:15 – How OpenAI is able to score well on health evals 00:14:21 – Key challenges deploying AI in healthcare 00:21:05 – Collaboration with hospitals and healthcare systems 00:23:05 – Practical everyday uses of AI health assistants 00:26:43 – Biggest “wow” moment during development 00:28:46 – Feedback from clinicians and early users

SPEAKERS

  • Andrew Mayne

    host

    Host of the OpenAI Podcast.

  • Karan Singhal

    guest

    Leads Health AI Research at OpenAI, focusing on model training, evaluation, and deployment in clinical workflows.

  • Dr. Nate Gross

    guest

    Head of Health at OpenAI and a physician with clinical training (including Emory/Grady) focused on applying AI in healthcare.

EPISODE SUMMARY

In this episode of OpenAI, featuring Andrew Mayne and Karan Singhal, Building AI for better healthcare — the OpenAI Podcast Ep. 14 explores openAI’s approach to safe, context-aware AI in healthcare workflows OpenAI frames healthcare as a high-impact, high-stakes domain where AI can expand access, reduce gaps in care, and support both patients and clinicians at scale.

RELATED EPISODES

Why AI needs a new kind of supercomputer network — the OpenAI Podcast Ep. 18

Why AI needs a new kind of supercomputer network — the OpenAI Podcast Ep. 18

What happens now that AI is good at math? — the OpenAI Podcast Ep. 17

What happens now that AI is good at math? — the OpenAI Podcast Ep. 17

Sam Altman on AGI, GPT-5, and what’s next — the OpenAI Podcast Ep. 1

Sam Altman on AGI, GPT-5, and what’s next — the OpenAI Podcast Ep. 1

How AI is accelerating scientific discovery today and what's ahead — the OpenAI Podcast Ep. 10

How AI is accelerating scientific discovery today and what's ahead — the OpenAI Podcast Ep. 10

Inside ChatGPT, AI assistants, and building at OpenAI — the OpenAI Podcast Ep. 2

Inside ChatGPT, AI assistants, and building at OpenAI — the OpenAI Podcast Ep. 2

Episode 15 - Inside the Model Spec

Episode 15 - Inside the Model Spec

Get more out of YouTube videos.

High quality summaries for YouTube videos. Accurate transcripts to search & find moments. Powered by ChatGPT & Claude AI.

Add to Chrome