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224 ‒ Dietary protein: amount needed, ideal timing, quality, and more | Don Layman, Ph.D.

Watch the full episode and view show notes here: https://bit.ly/3Sm7snG Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Don Layman is a Professor of Food Science and Human Nutrition at the University of Illinois Urbana-Champaign. He has spent the past 40 years investigating the role of dietary protein in muscle protein synthesis. In this episode, Don describes how his decades of research have shaped his thinking around protein, muscle, anabolic factors, metabolism, and more. He explains the recommended dietary allowance (RDA) for protein: what it is, how it came about, and how it should serve only as a guide for the minimum protein necessary for survival rather than as an optimal level of protein intake. He provides an overview of the essential amino acids, explains the nuances of animal versus plant protein, and provides insights for determining protein quality, absorption rates, and how to best track your intake. He discusses the ideal timing of protein intake in relation to resistance exercise, how protein should be distributed among meals, and how limitations in protein utilization per sitting can impact those practicing time-restricted eating. Additionally, Don shares results from his clinical trials, including how a high-protein diet fared in terms of fat loss, and explains the differences in protein utilization between adolescents and adults and how the problem of reduced efficiency of protein utilization in older adults can be overcome. We discuss: 0:00:00 - Intro 0:00:08 - Don’s background: from growing up on a farm to studying nutritional biochemistry 0:04:39 - Don’s philosophy on nutrition, muscle, and metabolism 0:18:10 - The controversial relationship between saturated fat and atherosclerosis 0:26:30 - The basics of protein and amino acids 0:33:46 - Origin and limitations of the current recommended dietary allowance (RDA) for protein intake 0:43:44 - Protein sources: determining quality, absorption rates, and how to track intake 0:51:35 - Leucine, lysine, and methionine: three important essential amino acids 0:57:35 - The vital role of ruminant animals in the production of quality protein 1:04:55 - The differing needs and impacts of dietary protein for a 16-year old compared to a 65-year old 1:12:50 - Consequences of protein deficiency in childhood 1:19:50 - Muscle protein synthesis: ideal timing, small meals vs. big meals, and more 1:27:51 - Protein needs of children 1:33:07 - How important is timing protein intake around training? 1:37:27 - The role of leucine in fatty acid oxidation by muscle 1:41:07 - High protein diets for fat loss: Results from Don’s clinical trials 1:55:24 - Influence of industry funding on nutrition studies 2:01:26 - Don’s thoughts on plant-based and synthetic “meats” 2:10:05 - Problems with epidemiological studies of dietary protein -------- About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 45 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life). Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies.

Peter AttiahostDon Laymanguest
Sep 26, 20222h 14mWatch on YouTube ↗

Episode Details

EPISODE INFO

Released
September 26, 2022
Duration
2h 14m
Channel
Peter Attia MD
Watch on YouTube
▶ Open ↗

EPISODE DESCRIPTION

Watch the full episode and view show notes here: https://bit.ly/3Sm7snG Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Don Layman is a Professor of Food Science and Human Nutrition at the University of Illinois Urbana-Champaign. He has spent the past 40 years investigating the role of dietary protein in muscle protein synthesis. In this episode, Don describes how his decades of research have shaped his thinking around protein, muscle, anabolic factors, metabolism, and more. He explains the recommended dietary allowance (RDA) for protein: what it is, how it came about, and how it should serve only as a guide for the minimum protein necessary for survival rather than as an optimal level of protein intake. He provides an overview of the essential amino acids, explains the nuances of animal versus plant protein, and provides insights for determining protein quality, absorption rates, and how to best track your intake. He discusses the ideal timing of protein intake in relation to resistance exercise, how protein should be distributed among meals, and how limitations in protein utilization per sitting can impact those practicing time-restricted eating. Additionally, Don shares results from his clinical trials, including how a high-protein diet fared in terms of fat loss, and explains the differences in protein utilization between adolescents and adults and how the problem of reduced efficiency of protein utilization in older adults can be overcome. We discuss: 0:00:00 - Intro 0:00:08 - Don’s background: from growing up on a farm to studying nutritional biochemistry 0:04:39 - Don’s philosophy on nutrition, muscle, and metabolism 0:18:10 - The controversial relationship between saturated fat and atherosclerosis 0:26:30 - The basics of protein and amino acids 0:33:46 - Origin and limitations of the current recommended dietary allowance (RDA) for protein intake 0:43:44 - Protein sources: determining quality, absorption rates, and how to track intake 0:51:35 - Leucine, lysine, and methionine: three important essential amino acids 0:57:35 - The vital role of ruminant animals in the production of quality protein 1:04:55 - The differing needs and impacts of dietary protein for a 16-year old compared to a 65-year old 1:12:50 - Consequences of protein deficiency in childhood 1:19:50 - Muscle protein synthesis: ideal timing, small meals vs. big meals, and more 1:27:51 - Protein needs of children 1:33:07 - How important is timing protein intake around training? 1:37:27 - The role of leucine in fatty acid oxidation by muscle 1:41:07 - High protein diets for fat loss: Results from Don’s clinical trials 1:55:24 - Influence of industry funding on nutrition studies 2:01:26 - Don’s thoughts on plant-based and synthetic “meats” 2:10:05 - Problems with epidemiological studies of dietary protein -------- About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 45 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life). Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies.

SPEAKERS

  • Peter Attia

    host

    Physician and host of The Drive podcast, focused on longevity and metabolic health.

  • Don Layman

    guest

    Nutritional biochemist and protein metabolism researcher (Ph.D., University of Minnesota).

EPISODE SUMMARY

In this episode of Peter Attia MD, featuring Peter Attia and Don Layman, 224 ‒ Dietary protein: amount needed, ideal timing, quality, and more | Don Layman, Ph.D. explores don Layman on Protein Needs, Leucine, Timing, and Muscle-Centric Health Layman argues the RDA of 0.8 g/kg comes from flawed nitrogen balance methods built on growth studies, and that adults, especially older ones, do better at about 1.6 g/kg.

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