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Peter Attia MDPeter Attia MD

322 - Bone health for life: building strong bones, preventing age-related loss, osteoporosis, & more

View show notes here: https://bit.ly/3A4ioCW Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Belinda Beck, founder of The Bone Clinic and a leading authority on exercise physiology and bone health, delves into the science of osteoporosis, bone density, and the lifelong importance of maintaining skeletal health. In this episode, she explains how the foundation for strong bones is established during childhood, offering valuable advice for parents on optimizing bone health for their kids. She also explores how bone remodeling occurs throughout life, driven by activity, nutrition, and hormones. Belinda highlights the power of resistance training in improving bone strength, even for those at risk of bone loss, and emphasizes the role of essential vitamins and minerals in maintaining bone health. She shares practical strategies, backed by research, for preventing fractures and combating osteoporosis. We discuss: 0:00:00 - Intro 0:00:59 - Belinda’s journey into bone health research and training 0:07:12 - The physiology of bone and how bones adapt to mechanical loading 0:13:51 - Bone development from birth to adulthood, why early life is a crucial period, the functions of osteoblasts and osteoclasts, and gender differences in BMD 0:29:05 - How parents can optimize their children’s bone health through diet (calcium and vitamin D), sunlight exposure, and physical activity 0:50:25 - The best sports and activities for promoting bone health, weight training for kids, and advice for parents 0:53:00 - The impact of corticosteroid use on bone health in children and strategies to minimize negative effects 0:57:15 - Advice for people in middle age to preserve bone density: physical activity and bone-loading exercises 1:06:08 - Bone loss during the menopause transition for women: hormone replacement therapy and other strategies to mitigate BMD losses 1:10:20 - Interpreting the bone mineral density results from a DEXA scan: T-score, Z-score, and more 1:18:30 - The LIFTMOR study: testing the effects of heavy weightlifting on bone health in postmenopausal women with low bone density 1:29:05 - Profound benefits of weight training outside of BMD improvements: exploring the broader impacts on patients in the LIFTMOR study 1:40:48 - Guidance for people wanting to use exercise designed to improve their bone health -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: https://peterattiamd.com/terms-of-use/

Belinda BeckguestPeter Attiahost
Oct 21, 20241h 48mWatch on YouTube ↗

At a glance

WHAT IT’S REALLY ABOUT

Belinda Beck on Building Bone and Reversing Loss Through Heavy Lifting

  1. Beck explains that bone adapts to the loading it chronically experiences (Wolff's law), with osteoblasts forming bone, osteoclasts resorbing it, and peak bone mass reached by roughly the end of the second decade.
  2. For children, she recommends adequate calcium (about 1,000 mg a day by the teenage years), vitamin D from sun or supplements, and daily vigorous, varied, high-impact activity, noting there is no evidence that weight training stunts growth.
  3. She and Peter Attia argue that much age-related bone and muscle decline reflects sedentary behavior rather than inevitable aging, and that drugs are unlikely to replace the stimulus of mechanical loading, though Attia also highlights estrogen's importance around menopause.
  4. Beck walks through interpreting DEXA results, explaining that BMD is an areal measure, that osteoporosis is diagnosed from hip and spine scans rather than whole-body scans, and how T-scores differ from Z-scores.
  5. The LIFTMOR trial had postmenopausal women with low bone mass lift heavy free weights twice weekly for 30 minutes, producing spinal BMD gains, thicker femoral neck cortex, better function and posture, and large quality-of-life improvements, and Beck describes how people can access supervised programs.

IDEAS WORTH REMEMBERING

5 ideas

Childhood is the critical window for building bone.

Beck says bone growth is largely finished by the end of the second decade, with nobody growing bone after about 30, and genes set an estimated 70-80% of bone mass, so the goal in youth is to reach as much of one's genetic potential as possible.

High-load, varied activity matters most for bone.

Swimming, cycling and walking are great for other tissues but do little for bone, while jumping, landing, and strong muscle movements that bend bone stimulate adaptation; athletes who played multiple sports were better protected than runners who only ran.

Estrogen loss drives rapid bone loss after menopause.

Because estrogen restrains osteoclasts, women lose bone quickly for roughly five to eight years after menopause, and Attia stresses that waiting until menopause is complete to address estrogen means substantial bone has already been lost.

Age-related bone decline may largely reflect sedentary behavior.

Beck cites masters athlete data showing BMD and muscle are maintained when activity is maintained, calling the typical decline an atrophy effect rather than a genetically programmed aging effect.

Older people with osteoporosis can safely lift heavy with proper coaching.

In LIFTMOR, women trained systematically from a broomstick up to heavy deadlifts and squats at about 85% of one-rep max, with technique and extension emphasized, and no one was harmed; Beck stresses coaches need clinical training.

WORDS WORTH SAVING

5 quotes

old people are you and me who just kept living longer.

— Belinda Beck

older people are perfectly capable of learning how to do a deadlift and a squat. You know, it might be pretty ugly to start with, but they get better. And as they get stronger, they get even better.

— Belinda Beck

This is a sedentary, um, problem. This is not an age problem.

— Belinda Beck

I think we will struggle to ever find a drug that will be able to replicate, uh, the action of exercise, physical loading on muscle and bone, because you can't replicate the stimulus.

— Belinda Beck

There is nothing that a pill can do to touch the benefits of exercise.

— Peter Attia

Wolff's law and bone adaptation to loadingOsteoblasts, osteoclasts, and estrogen's roleChildhood bone building: calcium, vitamin D, and sportBest activities for bone: impact, variety, and weight trainingCorticosteroids and bone healthInterpreting DEXA T-scores and Z-scoresLIFTMOR trial and heavy resistance training for osteoporosis

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