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Peter Attia MDPeter Attia MD

330 – Autism, ADHD, and Anxiety: the rise in autism & an approach to diagnosing & treating children

View show notes here: https://bit.ly/3W68vwy Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Trenna Sutcliffe is a developmental behavioral pediatrician & the founder & medical director of the Sutcliffe Clinic in the San Francisco Bay Area, where she partners with families to provide care for children facing behavioral challenges, developmental differences, & school struggles. In this episode, Trenna shares her journey into developmental & behavioral pediatrics, including her pioneering work at Stanford & her expertise in autism, ADHD, & anxiety—the "three As." She explores the diagnostic processes, the overlap & comorbidities of these conditions, & the importance of personalized treatment plans that address both medical & environmental factors. Trenna offers valuable insights into the changing prevalence of autism, the impact of evolving diagnostic criteria, & the range of therapies & medications available to support children & their families. She also discusses the challenges in accessing care & the critical need for a holistic approach that bridges healthcare & education. We discuss: 0:00:00-Intro 0:01:09-A passion for developmental-behavioral pediatrics (DBP), & the process of diagnosing anxiety, ADHD, & autism 0:08:53-Anxiety & ADHD: assessing impairment & self-esteem & identifying anxiety & emotional well-being in young patients 0:16:45-Evolving diagnosis of autism: the spectrum & individual needs 0:28:32-Dramatic rise in autism spectrum disorder (ASD): genetics, environment, expanded diagnostic criteria 0:41:40-Exploring epigenetics & the potential multigenerational impact of environment exposures on susceptibility 0:46:22-Evolution of autism classifications, & the particular challenges for children with mildautism due to a lack of support 0:54:20-Broadening of the autism spectrum: benefits/risks of expanded diagnostic criteria & the need to focus on better outcomes 1:05:49-Overlap between ASD, ADHD, & anxiety 1:09:57-Understanding oppositional defiant disorder, & the importance of understanding the “why” behind a behavior 1:17:05-Defining developmental-behavioral pediatrics (DBP) 1:25:08-Updated methods of ABA (applied behavioral analysis) therapy: evolution, controversies, challenges of scaling autism care, & tailored interventions 1:36:21-Tips for parents trying to find & evaluate care for children with autism, ADHD, or anxiety 1:43:51-Tailored treatments for ADHD: balancing stimulant medications with behavioral training 1:56:28-The interplay between medication, behavioral therapy, & neuroplasticity in managing ADHD 2:02:10-Using medication to treat anxiety & other symptoms in kids with autism without ADHD 2:04:19-FAQs about medicating children with ADHD: benefits, side effects, dosage 2:06:52-The “superpowers” associated with level 1 autism 2:09:26-The next steps to increase support for children with ASD, anxiety, & ADHD -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, & all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, & much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan & simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only & does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information & the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, & they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures & the companies I invest in or advise, please visit my website where I keep an up-to-date & active list of such companies. For a full list of our registered & unregistered trademarks, trade names, & service marks, please review our Terms of Use: https://peterattiamd.com/terms-of-use/

Trenna SutcliffeguestPeter Attiahost
Jan 6, 20252h 15mWatch on YouTube ↗

At a glance

WHAT IT’S REALLY ABOUT

Developmental pediatrician explains diagnosing and treating autism, ADHD, and anxiety in children

  1. Sutcliffe explains that anxiety, ADHD, and autism are clinical diagnoses with no biomarkers, so they depend on expert assessment across settings and on whether traits cause real impairment in a child's function and self-esteem.
  2. The conversation covers the rise in autism to 1 in 36, with Sutcliffe saying broader criteria and awareness don't fully explain it, that autism is highly heritable but polygenic, and that environmental and epigenetic factors remain unsettled.
  3. Sutcliffe and Attia discuss the 2013 DSM-5 merging of Asperger's, PDD-NOS and autistic disorder into one spectrum, weighing better access to services against over-pathologizing and the neglect of level 1 children.
  4. Sutcliffe stresses understanding the 'why' behind behaviors such as oppositional behavior rather than relying on labels, and describes treatment as individualized, combining behavioral therapy, parent training, school collaboration, and medication when helpful.
  5. The episode closes with practical guidance for parents finding care and Sutcliffe's view that closing the supply gap requires more trained professionals, new reimbursement models, and a bridge between healthcare and education.

IDEAS WORTH REMEMBERING

5 ideas

Diagnoses are man-made boxes, and impairment is what matters

Sutcliffe says there are no blood tests or scans for these conditions, and traits only become a disorder when they impair a child's function, relationships, learning, and self-esteem.

A label alone says little about the child

Sutcliffe repeats that 'if you've met one child with autism, you've met one child with autism,' and says a diagnosis is mainly a tool for understanding the child and unlocking resources.

Understanding the 'why' drives treatment

She says oppositional behavior may stem from anxiety, impulsivity, social difficulties, or sensory overload, and that a label like ODD gives her nothing to treat, whereas the underlying cause does.

The autism increase is real but not fully explained

Sutcliffe says people in the field believe changed definitions, awareness, and resources don't explain the numbers, and that autism has very high heritability involving many genes plus possible environmental and epigenetic hits, with both speakers noting epigenetic inheritance is unproven.

Level 1 autism children often fall through the cracks

Because they have many strengths, level 1 kids frequently don't get support even though Sutcliffe says they respond well to coaching, and clinicians may label them with autism or ADHD plus anxiety.

WORDS WORTH SAVING

5 quotes

It's not just about the diagnosis, it's the journey afterwards, and it's really about personalized care.

— Trenna Sutcliffe

To me, if someone tells me their child has autism, I actually really don't know much about their child.

— Trenna Sutcliffe

I'm concerned that people get stuck on a name and don't actually see the person beneath that name.

— Trenna Sutcliffe

The purpose of a diagnosis in anywhere in medicine should be to impact an outcome. A diagnosis for the sake of a diagnosis is not a particularly valuable tool unless you're an epidemiologist.

— Peter Attia

I think of myself as a Sherpa sometimes, guiding people along this journey.

— Trenna Sutcliffe

Diagnosing anxiety, ADHD, and autism without biomarkersImpairment and self-esteem as diagnostic anchorsRising autism prevalence, genetics, and epigeneticsDSM-5 changes and level 1 autismOverlap of ASD, ADHD, and anxietyABA therapy and parent trainingADHD stimulant and non-stimulant medications

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