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Peter Attia MDPeter Attia MD

371 – Women’s sexual health: desire, arousal, and orgasms, navigating perimenopause, and more

Sally Greenwald is an OB-GYN who specializes in women’s sexual health from a hormonal and physiologic perspective, with expertise spanning desire, arousal, pelvic floor function, contraception, and menopause care. In this episode, she explains why sexual health is a vital component of overall well-being, exploring topics such as the drivers of desire, the anatomy of sexual function, myths and realities around orgasm, and the role of hormones in perimenopause and menopause. She also covers vaginal and pelvic health, pain with sex, evidence-based therapies for low desire and arousal, how contraception and medications can affect sexual function, and practical strategies for enhancing sexual satisfaction and maintaining intimacy across life stages. This episode offers a comprehensive, evidence-based discussion with immediate real-world relevance for women as well as for men who want to better understand their partners. View show notes here: https://bit.ly/3XbPAjH Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ We discuss: 0:00:00 - Intro 0:00:11 - How sexual health influences physical health, emotional well-being, and relationships 0:10:21 - Understanding the physiology of the female orgasm, sexual comfort and satisfaction, and the disparity between men and women 0:16:57 - Foreplay, the science of desire, and methods to help women cultivate arousal and connection 0:22:10 - The physiology and sources of female lubrication, the role of clitoral nerve anatomy in pleasure, and the use of lubricants and vibrators to enhance comfort and sexual health 0:30:19 - Understanding female anatomy and what is needed for orgasm 0:41:40 - Understanding sexual desire, how to cultivate it, the role of hormones, and testosterone therapy in women 0:50:48 - Personalizing perimenopause care: how desire for ovulation guides the choice between contraception and menopausal hormone therapy 1:02:13 - Considerations for choosing contraceptives and hormonal therapies during perimenopause 1:15:11 - Factors negatively affecting desire, and why female libido persists with age and fluctuates across the menstrual cycle 1:19:48 - How sexual trauma and physical pain can affect sexual health, and evidence-based strategies for recovery 1:24:29 - Vaginal care routine: lubricants, moisturizers, topical hormones, and other approaches for vaginal health 1:32:05 - Tips for sexually satisfying your female partner 1:37:15 - The pharmacology of arousal: various treatments for low sexual desire in women 1:45:31 - Sex during and after pregnancy: impact on arousal, safety of sex, and how to manage postpartum recovery and pain 1:50:24 - How Sally would redesign sex education 1:58:22 - Sally’s optimism about a new era in women’s sexual health -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: https://peterattiamd.com/terms-of-use/

Peter AttiahostSally Greenwaldguest
Nov 3, 20252h 0mWatch on YouTube ↗

At a glance

WHAT IT’S REALLY ABOUT

OB-GYN Sally Greenwald on Female Desire, Orgasm, Perimenopause, and Sexual Health

  1. Greenwald argues sexual health is health, citing links to sleep, relaxation and exercise-like energy use, and says desire discordance between partners, not frequency, is the main divorce risk factor.
  2. She describes a large orgasm gap (about 95% of men versus 30% of women usually orgasm with a partner) and explains that most women need external clitoral stimulation, adequate foreplay, and responsive rather than spontaneous desire.
  3. On hormones, she says testosterone is well-studied for hypoactive sexual desire disorder, and she frames perimenopause care around whether a woman likes to ovulate, which guides the choice between contraceptives and menopause hormone therapy.
  4. She recommends a vaginal care routine modeled on facial skincare: lubricant (silicone-based or osmolality near 300), vaginal moisturizers, and local estrogen, plus pelvic floor physical therapy.
  5. She also covers trauma recovery with sensate focus, drugs and cannabis for low desire, sex in pregnancy and postpartum, and a redesign of sex education that is anatomical and pleasure-informed rather than fear-based.

IDEAS WORTH REMEMBERING

5 ideas

Sexual health belongs on the longevity agenda

Greenwald cites better sleep and parasympathetic activation after sex, and Attia notes about two-thirds of his patients pick sex for their marginal-decade activities, which links to maintaining VO2 max.

Desire discordance matters more than frequency

Greenwald says divorce risk is similar across frequencies; the risk factor is one partner wanting more and the other less.

Most women need external clitoral stimulation and time

She says fewer than 10% orgasm from penetration alone, so foreplay, vibrators and manual stimulation are normal tools, and foreplay over 21 minutes is associated with orgasm in over 90% of women.

Women's desire is often responsive, so arousal can come first

Only about 15% of women have spontaneous desire, so she suggests lube beforehand, erotic reading, mindfulness, vibrators, and scheduled sex to build arousal.

Ask 'do you like ovulating?' to guide perimenopause treatment

She says about 70 to 80% of her patients prefer not to ovulate, and that answer steers choices between contraceptive pills, drospirenone, estradiol patches, and menopause hormone therapy.

WORDS WORTH SAVING

5 quotes

if sexual health is health and women are not experiencing it with the same amount of pleasure that men are, this is a health disparity.

— Sally Greenwald

I would like to encourage you to think about taking care of the vagina like you take care of your face.

— Sally Greenwald

If you're waiting for your husband to get a new shirt or a new Selby or anything, it... The visual stimulus is not evidence-based. Stop waiting for that.

— Sally Greenwald

if you want to be able to have sex in your marginal decade, you need to have a VO2 max of probably about 30 milliliters per kilogram per minute.

— Peter Attia

I think sexual health as a part of your health and talking about it in a very sort of like generic safe place from a physiologic perspective.

— Sally Greenwald

Sexual health and longevityOrgasm gap and clitoral anatomyResponsive versus spontaneous desireTestosterone and perimenopause hormone choicesLubricants, moisturizers and vaginal careTrauma, pain and pelvic floor therapySex education reform

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