Fastest Way To Decreased Lifespan – & You’re Doing It Daily! (Prevent Disease With This One Habit)

1. 0:00 – 2:13

   Why sunlight deficiency shows up as fatigue, inflammation, and higher mortality risk

   1. RCDr. Rangan Chatterjee0:00

      Right at the top, I wonder if we could start with the common signs that might indicate someone has a deficiency of sunlight in their life.

   2. RSDr. Roger Seheult0:12

      It could be a whole host of things. When you look at the studies of lack of sunlight or the studies where people get enough sunlight, we're literally talking about mortality. Um, and, uh, we can get into this later, but if you look at the particular causes of death as you go into the winter season, it's infectious diseases, it's non-infectious diseases. So it's gonna be interesting to sort of pin down exactly what symptoms they would be. But if we had to do that, I would say things like fatigue, inflammation, pain, inability to sleep. I mean, these are very broad, uh, symptoms, but symptoms nonetheless. I mean, there's also, uh, laboratory findings, for instance, elevated cholesterol, elevated triglycerides. These are things that have actually been statistically shown to improve when the-- there is more sunlight in the forecast or in the, in the weather report for those periods of days where, uh, those, those subjects are actually tested. There was a, an Oxford study that actually looked at that, that we can get into. So it's, it's really, um... Look, if I were to say, what is the single biggest intervention that someone can do right away that would show not only benefits in the short run, but also in the long run, and is the lowest hanging fruit, there's no question in my mind that sunlight is, is that intervention.

   3. RCDr. Rangan Chatterjee1:33

      That is such a bold statement in many ways. It's a statement that many people have probably not heard of before through the lens of health. Because when we think about health, we're thinking about nutrition, exercise, sleep, and of course, these things are important. But I guess the thing about sunlight, and I guess broadly speaking, natural light, is that we've not really prioritized it or spoken enough about it for quite a while now, have we?

2. 2:13 – 5:09

   We used to design hospitals for light: Florence Nightingale and the lost wisdom

   1. RSDr. Roger Seheult2:13

      That is, that is true. And if we look back historically, this was not something that we ignored, uh, historically in terms of health. Uh, if we just go back 100, 120 years, and, you know, uh, I always like to, to reminisce on this. You know, a building in the United States that's 100 years old, it could be a historical monument. Uh, in, in the UK, not so much. I mean, you have buildings there going back hundreds of years, more than hundreds of years, and you can see hospitals, buildings that were designed to heal, and you can see very clearly that they were designed when they're over 100 years old to bring light in, to bring fresh air in. And, um, uh, look, I'm not telling you something that you don't already know. Florence Nightingale, who by many have been considered to be the, the, the founder of modern nursing, said when she was taking care of, uh, of, uh, English soldiers in Crimea, said, "Look, there's two things that I see that have the biggest impact on the health of my patients. Number one, fresh air, but a close second to that is, is light, sunlight, not just daylight, but direct sunlight." And she's quoted as saying that, and she was... No, she was there. She was at the bedside. She was known as the, the Lady with the Lamp. And, um, that was well known, uh, at the time, and we have sort of forgotten, uh, about that. But with the benefits of modern science and, uh, and technology, we can now actually literally get down to the molecular levels and show how getting out in sunlight can be tremendously beneficial on so many different levels.

   2. RCDr. Rangan Chatterjee3:50

      Yeah, it's interesting. As I was thinking about our conversation today, I was thinking about why is it that we have perhaps undervalued natural light and sunlight over the past few decades? And of course, we can say that there wasn't enough science, and as the scientific studies are done, there's more awareness, so we can put that into practice. And I, and I think there's definitely some merit to that. At the same time, I think sometimes it comes down to what we can easily see, right? So we can see the food on our plates. We, we know what we're putting into our mouth. We can see how many steps we've taken or whether we've gone to the gym or not, right? So these things are easier to visualize and to track. But I've often thought stress is undervalued in terms of the impact it has on us because a lot of stress is invisible. We can't see it, and you can perhaps make the same case for light. Yeah, of course, the sun we can see, but as we're gonna dive into, you know, sunlight is-- there's visible things coming from the light, there's invisible things coming from the light. So I wonder if some of this is to do with, like, literally the visibility of these components in our life.

3. 5:09 – 8:14

   Making invisible light visible: infrared photography and what indoor life blocks

   1. RSDr. Roger Seheult5:09

      Absolutely. And that's what I've tried to, and you've tried to bring to people who are watching and who are interested in this, is to make health graspable at, at any level so that people can understand that. Um, I, I have to confess, and we'll get into this later, I have just come across a, a wonderful little device that, um, I, I love to use, and I can probably share some of these things later. It's a little film, and in the line of what you're talking about, it's a little film that you put over the lens of your smartphone camera, and what it does, using actually some, some quantum, uh, physics, is it'll take very-- it'll take infrared light, which has a lower energy, and using, uh, rare earth metals and some anti-Stokes effects and some physics, it'll actually, uh, shift the frequency of that high enough up into the visible spectrum so that you can actually see-The type of light that we're gonna talk about today, which is primarily infrared light, and you put this over your camera, and it's like Christmas morning for me, literally. I'm, I mean, I'm going out everywhere. I'm shooting things. My kids think I'm crazy. But it's, it's an amazing transformation where you can literally see the light coming off of the leaves. You can see what, what's going on inside, when you come into your house, how dark it is because there's a complete, uh, absence of infrared light. You can see how much the windows are preventing that light from coming in when you open one of them, and you can see the difference. Um, it's, it's quite stark. And, and I've been posting actually these things on social media, and you're absolutely right. People are like, "Wow, I've heard you talk about infrared light, but I had no idea that that's how much light was literally coming off of the trees, and this is how much light is literally being blocked by the windows that are supposed to be letting this light in." Um, and it's so devoid in- inside the homes where we spend 93% of our lives. And what you just said is, is so true about the fact that we can't see some of the most beneficial, uh, effects of the sun.

   2. RCDr. Rangan Chatterjee7:12

      I follow you on X, uh, Roger, and I've been very much enjoying all these photos that you've been posting actually because it does make the invisible visible. And I've been aware, and like you've been writing about this so many, is the importance of light. But I don't think I had that full appreciation of infrared light and actually how important it is, and literally when you come from outside to inside, it, it goes down dramatically. So I mean, we're gonna talk about that, but perhaps we should just zoom out a little bit and go, okay, so some of this thing is getting so far that, look, light is important, okay? We know that getting outside is important, and many people maybe as a kid were told by their parents, "Get outside and play," okay? But let's really try and unpick what is it about being outside that has all of these different aspects on our health? Because it's not all infrared light, is it? There's other components as well.

4. 8:14 – 18:01

   The 'macronutrients of light': visible, UV, and infrared—and what each does

   1. RSDr. Roger Seheult8:14

      Absolutely. So when we look at the light that's coming from the sun, there's basically three types of light that we wanna talk about. There is obviously the visible light, which you can see, and there is countless studies and decades of research that shows that visible light itself has a tremendous health benefit on the individual. Why? Number one, it prevents, uh, depression. So we know that people who live at high latitudes who are not exposed to enough visible light, especially during the winter months when the days are short, when they're getting up before the sun gets up and they're getting home after the sun goes down, they are susceptible to seasonal affective disorder. And a very easy way of overcoming that particular issue is with visible light into the retina that stimulates a portion of the brain that prevents, uh, depression from happening. So that's, that's visible light. That's that first aspect. We also know that visible light, especially early in the morning when the sun is coming up, helps to ground and to, um, establish a good circadian rhythm. There's something called the zeitgeber that affects the timing of all of the processes in your body, so visible light is important. So those two things right there are one of the, just the top of the list in terms of the things that visible light does when you get outside. Now, uh, in terms of the two types of invisible light, when we go past violet, we get ultraviolet light, and we all know that ultraviolet light, specifically ultraviolet light B, is very important in the production of vitamin D3 in our skin. So that type of high energy, so this is short wavelength, high energy, um, when you look at the visible spectrum, you have the colors of the rainbow. When you go off to the violet side, the wavelengths get shorter, and the, the amount of energy in those, uh, p- photons is much higher. They have the energy to penetrate just very shallowly into the skin, which is where they're needed, but the energy that they deliver is enough to actually break the bonds in these molecules of cholesterol so that it can actually change it and convert cholesterol into vitamin D. So that's... We know all about [chuckles] well, we know a lot about vitamin D. We've known about it for a long time, and we often, uh, to our detriment, simply chalk up sunlight and sunlight exposure just to giving us vitamin D. Now, surely it gives us vitamin D, um, and vitamin D is very important. There's a number of trials that show that vitamin D is important, and I supplement as well, and it's, I think it's a good idea to supplement if you're, if you're low. Um, vitamin D is important, but that's just one aspect of, of invisible light. Okay, so we've talked about visible light. We've talked about ultraviolet light. Let's go to the other extreme. So past red. This is also invisible, but this is very long wavelength, and this is what we call infrared. And today we're gonna talk about red and infrared light. And there's, there's a couple of aspects of this light that's very important to understand, and that is, is that as opposed to short wavelength with, which has high energy, infrared light is a lower energy type of light with a long wavelength, but here's the key, and this is the point that people sometimes mix up. It's this long wavelength that's actually able, despite the fact that it's low energy, is able to penetrate deeply into the human body. And because of that, this is really important to understand, going outside into the sun on a sunny day is not just for the skin. It's not just for the eyes. It's for the entire body because this particular type of light-From the sun, which is long wavelength, has actually recently been shown. There's a paper by Glen Jeffrey from University College London, professor of ophthalmology. He's just published in Nature scientific reports that this type of light from the sun not only penetrates deeply into the human body, but he has actually been able to detect it on the other side of a human being. In other words, it goes right through.

   2. RCDr. Rangan Chatterjee12:33

      Yeah. It's amazing. As, as you were describing that, Roger, I was thinking, okay, we understand when we think about food that there are three macronutrients, right? Fats, protein, and carbs.

   3. RSDr. Roger Seheult12:48

      Yeah.

   4. RCDr. Rangan Chatterjee12:48

      So perhaps now we need to start thinking about light in the same terms. We're now saying, okay, there's light, but under light there's at least three different components, from what I'm understanding from you, okay? The first one is that visible light. So we can see that. That's why going out first thing in the morning is so good for our circadian rhythm. It helps set the kind of clock in all of our cells, and that can have an impact therefore on things like mood, sleep, and our gut. There's also a second type, which is the, the ultraviolet light, the UV light, and of course for many years we've heard about vitamin D and how important that is, and many people know that sunlight outside on your skin at certain times of year will increase your production of vitamin D. So that second component is the UV light that's gonna help with vitamin D, which of course has a very powerful effect on our immune system and many other things. And then there's this third component of light, which we're gonna spend a lot of time talking about today, which is infrared light. We cannot see this part of the light spectrum, but as you're gonna describe, it has a powerful effect on our mitochondria.

   5. RSDr. Roger Seheult14:06

      Yeah.

   6. RCDr. Rangan Chatterjee14:07

      And that's why if we sort of circle back to the start of this conversation, you said that going outside and getting sunlight is the most important thing that we can all do to improve our health, right?

   7. RSDr. Roger Seheult14:21

      Yeah.

   8. RCDr. Rangan Chatterjee14:21

      Which, which I love, because when we understand that the mitochondria sits at the heart of everything, and you're gonna ... You know, I've seen many of your MedCram videos where you've actually described the powerful effect that infrared light has on our mitochondria. You're like, well, of course. A lack of sunlight is potentially gonna be impacting energy, vision, heart disease, stroke-

   9. RSDr. Roger Seheult14:46

      Yep

   10. RCDr. Rangan Chatterjee14:47

       ... dementia, everything. So I know I said a lot there, but would you agree that it's helpful to think of this like the macronutrients of food? These are also the macronutrients of light perhaps.

   11. RSDr. Roger Seheult14:59

       You know, this, that ... I actually hadn't thought of it that way until you just mentioned it, but you're absolutely right. Food is a general category, as is light, but there's different aspects that that food provides in our body depending on our needs. And just like, um, proteins are important for muscle, and, and fats are important for myelin and the brain, and carbohydrates are also important in terms of energy, uh, that need, that i- is ne- necessarily immediately, so too is vitamin D needed, uh, for certain aspects, and the products of infrared ra- radiation is also important. So I think it's actually a very good analogy, and it makes us, uh, think about things holistically, and that's, that's really, I think, gonna be the underlying theme that we're gonna see today, is what we tend to do in science, I call it scientific reductionism, and other people have called that too, is where we find something that's beneficial, we try to isolate the active ingredient, we amplify it, and we put it into a pill, and we patent it, and we give it to people. And I guess what I'm saying here is that when you go outside, you're getting a whole buffet, a whole cornucopia of things that are mixed together dynamically, um, for your body at the right time. So think about this. You're ... It's a, it's an amazing situation. There is a clock in your body that is set by the sun, and as, as the day goes forward, the amount of ultraviolet light and infrared light that you're getting from the sun also changes along with that circadian rhythm. Is it possible that we were, uh, that, that we are, uh, c- connected to that circadian rhythm so that we're supposed to be getting lots of infrared light, uh, in the morning and lots of infrared light in the evening when that's abundant, and we are ready to take in ultraviolet light in, at noontime? I, I'm, I'm s- speaking out loud, I'm thinking out loud, but I think what, what people will see as we go through these studies and we get into the minutia of some of this, and the details, and the trials, and the evidence, is you'll start to see that really the best solution is not to go out and necessarily buy a, uh, a l- a lamp or a, um, a red light thing. I mean, those have their place, but if you have the ability and you can do this, it's to go outside into the sunlight, because everything that you need is literally right there.

   12. RCDr. Rangan Chatterjee17:22

       We're saying sunlight a lot, and of course, you know, any time it's day wherever you are in the world, yes, the sun is there causing that, you know, illuminating the planet for us. But of course sometimes we can see the sun directly, and other times it's hidden behind cloud. When it comes to these three macronutrients of light, as it were, is there a problem or how do we address, you know, receiving these nutrients if we live, let's say, in northern England, where I live, where-

   13. RSDr. Roger Seheult17:56

       Yeah

   14. RCDr. Rangan Chatterjee17:56

       ... it's not sunny all the time and often it is cloudy?

5. 18:01 – 21:50

   Infrared physics and penetration: clouds, water absorption, trees as IR mirrors

   1. RSDr. Roger Seheult18:01

      Yeah, that's, that is, uh ... That poses a problem. So let's, let's get into the physics of, of infrared light-

   2. RCDr. Rangan Chatterjee18:07

      Okay

   3. RSDr. Roger Seheult18:08

      ... and talk a lot about what it is, and what it does, and why it's important, and then it, it'll become clear about where we are with, with clouds. So, uh, and, and other things as well. So as we talked about, infrared light-Recently published article in Nature Scientific Reports, Glen Jeffrey took these people outside, and it was high noon, and there was no, no clouds in the sky, and he was able to show that infrared light literally goes through the body, can be detected out the other side. And the wavelengths in that paper that he found that were the best at doing this was in the infrared spectrum. No surprise. And specifically, he picked eight hundred and fifty nanometers, which is a wavelength that's, that's in the near infrared spectrum, but definitely cannot be seen by the human eye. So there's a couple of, of properties that you need to understand about infrared light in nature. Number one, as I said, it penetrates very well. Number two, it's, it's well-absorbed by water molecules. So there will be a diminution, a reduction in the amount of infrared light on a sunny day if there is cloud cover. That's going to diminish it, uh, somewhat. The other thing that's actually very interesting as well is that, uh, leaves on trees and grass are highly reflective of infrared light. You may have realized this, uh, independently. If you go out on a nice summer day, sunny day, and you touch leaves that have been in the sun for hours, um, they're not hot because they're reflecting the particular type of light that gives warmth from the sun. And you also know this, uh, when you go out on a sunny day. If you close your eyes, cover your eyes, [clears throat] someone spins you around, you can actually feel what side of the body your-- uh, is facing the sun. And the reason is, is because infrared light not only penetrates through your body, as we've just discussed, it can also very easily penetrate through your clothes. And so you can feel that. That warmth that you feel from the sun is infrared radiation penetrating deeply into your skin, going through, uh, the tissues, and activating the, the heat receptors as they go through. So, um, what I've done actually is, uh, in terms of your question about clouds, I've taken that infrared film, put it onto my iPhone. I've actually posted this, um, on the internet, and I've done this a very same time of day as there was clouds going overhead, and I took a, a photograph and a video of when it was full sun and when there was minimal sunlight, uh, because it was covered by clouds. And what you can see very clearly is that the amount of infrared light doesn't diminish that much because the leaves and the trees are so reflective of that, that infrared light's sort of spreading everywhere and, uh, and you can pick that up very easily on the film. I'll, I'll, I'll be happy to share those with you.

   4. RCDr. Rangan Chatterjee21:05

      What is the relevance of this idea that in the Glen Jeffrey study whereby, you know, the, the sun is coming onto us, but some of that light is going through us? What does that tell us?

   5. RSDr. Roger Seheult21:20

      So it was, it was a very small fraction of the light that was coming in the other side. So what it tells us is that it is able to come through, and it was a, it was a thorax, a chest, thirty centimeters measured, and it basically went right through, and they were able to measure a fraction of that light out the other side. And what the authors of that paper said was that clearly infrared light is able to penetrate into the body, be absorbed, but it's still able to penetrate

6. 21:50 – 31:13

   What infrared does biologically: mitochondria, aging energy decline, and vision gains

   1. RSDr. Roger Seheult21:50

      through thirty centimeters. Now, the question is, is what is it doing in the human body? What is it up to? What, what effects does this actually have? So I, I try to take this slowly with people because the first thing that people have difficulty understanding is that sunlight actually is affecting their entire body when they go outside, not just the skin. Once they understand that, the next question is, "Okay, well, what is this infrared light actually doing?" For that, we actually have multiple studies that have looked at this and, and all of them have been, uh, well, m- many of them have been o- on a petri dish or in a laboratory using infrared light from artificial sources, showing very amazing, uh, changes. And none of the scientists really understood at the time that this could be the effect from the sun because they, they had no idea that infrared light was able to penetrate that deeply. So if you look at the literature in the last ten, twenty years, you'll see people doing tests with, with, um, low-level laser therapy and things to see, you know, how deep does this go and, and the way they were doing the experiments was looking to see how much it penetrates in a straight line, and they were getting, you know, a, a few-- maybe a centimeter, maybe a few centimeters. Um, just back in twenty nineteen, Scott Zimmerman, uh, pu- published a paper in Melatonin Research that he predicted it would be about eight centimeters based on his research. Um, we now know it goes much more, much more deeply, and they're basically all of the cells of the human body, even through bone, infrared light can penetrate through. So think about the effects on the brain. The question again, and you alluded to this, is what is this infrared light actually doing in the human body? Well, we know it's actually affecting changes in the mitochondria, and this is the organelle of the cell that is responsible for producing energy. It's the batteries of the cell. Now, this is important for the obvious reason, but for another reason too, which is that we have seen scientifically with research that as we get older, as we, uh, age forty years, for instance, we can see a drop in the output of these mitochondria in our, in our cells by as much as seventy percent in the retina, but over the en- uh, entire human body, thirty to fifty percent in some cases. So there's a, there's a material drop in energy production, and what infrared light is doing is it is restoring in, in some way, in a, uh, in a partial way, the energy output and the efficiencyOf those mitochondria to restore energy to the cells, whatever they happen to be cells of what... or whatever organ they happen to be, and they're restoring the function of those cells. And this paper that Glen Jeffrey showed, in this case, he was checking for color vision, which is highly dependent on energy output, and it showed that in the retina, the mitochondria was able to effectively go up enough that the threshold for color blindness in these subjects dropped statistically significantly enough to show an improvement in their vision just with this type of light exposure.

   2. RCDr. Rangan Chatterjee24:58

      Yeah. It, it's certainly incredible. As you're describing that, Roger, I'm, I'm sort of thinking about a battery that we charge, right? So... Or a phone, right? We, we, we kind of understand the concept that our smartphone needs charging, right?

   3. RSDr. Roger Seheult25:12

      Yeah.

   4. RCDr. Rangan Chatterjee25:12

      So many of us in the evening, you know, uh, during the night, we'll charge our phones, so in the morning they're ready to do what we need them to do throughout the day. But if we think about light and the fact that we're living these indoor lives now, and yes, you mentioned scientific reductionism, of course, that absolutely plays into vitamin D, where for many years, you know, we've just thought sunlight equals vitamin D. It's like, no, no, wait a minute. Sunlight equals many things.

   5. RSDr. Roger Seheult25:41

      Yeah.

   6. RCDr. Rangan Chatterjee25:41

      One thing is vitamin D, [laughs] but there's many other things that sunlight does on our body as well. But maybe this infrared light is almost charging us, so our cells and our mitochondria are actually getting charged up, and if we live indoors and we're hardly exposing ourselves to natural light, maybe many of us are running around on low charge all the time, you know? It, it seems like-

   7. RSDr. Roger Seheult26:07

      Yep

   8. RCDr. Rangan Chatterjee26:07

      ... quite reasonable based upon the research and based upon what you're saying to think that actually we're, we're almost being suboptimal versions of ourselves by not getting out in the natural light and getting charged up.

   9. RSDr. Roger Seheult26:22

      That's a great analogy. You know, have you ever put your phone on low battery mode because you didn't-

   10. RCDr. Rangan Chatterjee26:27

       Yeah

   11. RSDr. Roger Seheult26:27

       ... have enough charge and you didn't... you couldn't get to a charger fast enough?

   12. RCDr. Rangan Chatterjee26:31

       Yeah.

   13. RSDr. Roger Seheult26:31

       It's, it's jittery, right? Uh, I mean, it doesn't work as fast. This is, this is, I believe, a very good analogy as to how we are functioning. When our mitochondria go down, our metabolism goes down. We gain weight. Uh, depending on the cell type that we're talking about, if it's in the brain, it's dementia. If it's in the heart, it's congestive heart failure. If it's in the pancreas, if it's in our peripheral tissues, it's insulin resistance. All of these things, uh, have been tied to mitochondrial dysfunction. Aging has been tied to mitochondrial dysfunction. And we can talk about some, some things that are, are, you know, maybe too early to talk about, uh, but COVID, long COVID, it's tied to mitochondrial dysfunction. And I think it was really, this is the reason why I'm here talking to you about this, because, you know, uh, in my day job, I'm a critical care physician taking care of patients in the ICU, and so I saw firsthand what was happening and it led me, it drove me to research more about what was going on. You know, why were my patients who were dying low with vitamin D? Why were my patients, uh, who were dying and infected with SARS-CoV-2 dying? And, and I started to find out that SARS-CoV-2 hits the ACE2 receptor, and the ACE2 is not just a receptor for the virus, it's also... it mitigates oxidative stress, and oxidative stress is the enemy of mitochondrial function. So all of these dots started to connect for me, and I started to research this more, and I found some amazing, uh, studies that have been done by individuals who are highly skilled, but they were in their silo, and I don't know if they really connected the dots. What I started to do was take research in all of these silos all across the world and start to put together a hypothesis. And at the end of the day, what I came across was that sunlight was very beneficial, and I thought I'd discovered something new. But in fact, we had known this all along. We just didn't have the scientific research. We had the empirical understanding, but not the scientific research on this. But yeah, the, the data is overwhelming. Um, and it's, um, it, it's amazing. We can get into that, but we're going down this path trying to explain what's going on, why we're going this way, what's going on in the individual human being, and then what we can do is we can show on an epidemiological basis what's actually happening, because the truth should be redundant.

   14. RCDr. Rangan Chatterjee28:55

       Yeah. What, what you said a short while ago, I think, i- is just worth double-clicking. I, like you, am really passionate that at the end of this conversation, people start taking their light exposure much more seriously. I have been using BON CHARGE wellness products for over five years. From blue light glasses to red light therapy, BON CHARGE make it really easy to get healthy while staying at home. Now, one of my current favorites is their Demi Red Light Therapy device. There are just so many studies now showing the potential benefits of red light therapy, including better eye health, pain relief, reduced inflammation, enhanced recovery, improved sleep, and even better skin. In fact, when it comes to skin, I have many friends and family members who absolutely love the BON CHARGE Red Light Face Mask. Super light and portable, and after using it for just 10 minutes a day, are reporting more radiant and glowing skin. So if you're looking to take charge of your health at home, I would highly recommend you check out BON CHARGE. They are giving my audience 20% off all of their products. Just go to boncharge.com/livemore and use the coupon code LIVEMORE to save 20%, or click on the link in the description box below, or scan the QR code on screen.You've mentioned this, and, you know, I've covered this on the podcast many times in the past, that when our mitochondria are not working well, so when we have mitochondrial dysfunction, it can cause a whole variety of different problems. Heart disease, type 2 diabetes, obesity, dementia, inflammation, as you've mentioned, long COVID, even some cases of cancer, right? So-

   15. RSDr. Roger Seheult30:54

       Yeah

   16. RCDr. Rangan Chatterjee30:54

       ... mitochondrial dysfunction right there at the heart. And what you're saying from the research is that one of the ways in which we can address this mitochondrial dysfunction is to get large amounts of infrared light. And the way you get that infrared light is by going outside.

7. 31:13 – 35:19

   How much sunlight is enough: biphasic dosing, shade strategies, and modern indoor traps

   1. RSDr. Roger Seheult31:13

      I would agree with that. Um, but I would also n- uh, and, and there's probably some people in there thinking, oh, I need to get out there for hours in the day. What ... It's, it's very interesting. In my discussions with Glen Jeffrey and Robert Fosbury, who also collaborated, who's an astrophysicist on this, is that you, you actually don't need to get out and have large amounts of infrared light, uh, to get these type of changes. Some people might out there be thinking, well, I've got very fair skin. I burn easily. Or I've got a history of melanoma, or maybe I've had melanoma or some sort of skin cancer. And here's the good news. The good news is, is that you don't need to have massive amounts of infrared light. You just need to have small amounts, and you can get it without even being directly in the sun. Um, I've, I've taken some photographs and I've, I've measured this. You can actually get outside in the shade, so long as you're surrounded by a lot of trees, it's bright. You're gonna be getting much more infrared light in that environment than you are in your office. And in fact, I would even go so far as to say this. There, there is an aspect of infrared light called the biphasic nature of infrared light, which means that after you get enough of this infrared light, further stimulation of infrared light is actually less and less beneficial. Let me give you, uh, some examples. When Glen Jeffrey did his studies on glucose metabolism and he took subjects and exposed them to this type of light on their back, it was, it was only for about 15 to 20 minutes. Uh, Glen Jeffrey has been working with, uh, flies and humans now for, for decades, and the mitochondria all act the same. Once you have about 15 to 20 minutes of this type of light, this effect actually lasts for days. Uh, he did, uh, an experiment, um, on, on people with, with difficulty with vision, and just shining light into their eyes for about three minutes actually had an effect for days on the mitochondria. So, so, um, it doesn't have to be for a very long time, but it does have to happen. And here's where we are with the population. Look, there are some people that get outside in the sun, they're gardeners. This message for them is probably not as essential because they're out there already. But for the majority of people, and I've looked at the statistics, I think in England it's, um, 92%. In the United States, it's 93%. That's how much time we're spending indoors-

   2. RCDr. Rangan Chatterjee33:42

      Right

   3. RSDr. Roger Seheult33:43

      ... away from sunlight. And so we are talking about a huge amount of the population at very one extreme that maybe just 50 or 100 years ago, that was not the case. We were outside. We were in the sun, we were getting around, and that was enough. Uh, but now what we're talking about is, uh, people who get up in the morning, go to their car in their garage, drive to a covered parking lot, go to their office, spend the majority of the day when the sun is out inside of an office surrounded by windows that block infrared light and lit by bulbs that don't have any infrared light, come home, and they come home after the sun goes down, and they go back to their home, and they expose themselves to light at night working on their computer. And this is their existence literally for weeks on end until maybe, uh, the weekend comes and, uh, the sun happens to be up and they get outside and they get some sunlight. And so this is the existence that we're talking about. And what I'm saying is that they should make a concerted approach, a concerted effort that's very important to get outside for just literally just 20 minutes, 30 minutes if, if the sun is low in the sky, and to get that sunlight on their body on a daily basis. That right there can actually have a tremendous benefit on their health. It doesn't need to be sunbathing every single day. And it, and they don't need, necessarily need to get, uh, light panels to do this type of work, but just getting outside in the sun on a daily basis is very important.

8. 35:19 – 41:00

   Personal changes and the 'infrared scurvy' idea: why modern lighting removed a key spectrum

   1. RCDr. Rangan Chatterjee35:19

      What have you changed in your own life over the past two to three years, having, you know, gone deep into this area of research?

   2. RSDr. Roger Seheult35:27

      So I, I am a physician, and, uh, my, the nature of my work, uh, being in the hospital is shift work. So I'm in, in the hospital at 7:00 in the morning, and I get out at 7:00 at night. And, um, the nature of that is, is that I'm not gonna get exposed to a lot of light. So I've, I've, I can't keep my mouth closed about it, so I tell everyone around me. And, um, and it used to be that I would go out at lunchtime in a little patio area that had a few, uh, picnic tables, and I would always make it a point never to eat lunch in the doctor's lounge, but to get outside in the sunlight. And I always noticed that it, it helped rejuvenate me. It gave me more energy for the afternoon. And, uh, as I started to, to say this more and more to other people, I found it more and more difficult to find a seat at lunchtime when I got outside because more people started to do exactly the same thing. And I started to talk to them, and, um, they also, either because of what I told them or because they've independently researched this as well. And so I've been trying to make it a point that on my lunch breaks or any type of breaks that I have, I try to get outside. I walk around, try to get as much sunlight as I possibly can. Because our lives have, have changed.In the last 50 years. We are now primarily indoor creatures who live in climate-controlled environments, who see the outside as being kind of wild, and, uh, we, we need more control. We don't like the heat, we don't like the cold, and that's a whole nother topic about how we're not exposing ourselves to that type of extremes, which is actually really important for our human body in terms of heat shock proteins and things. So we've, we've basically tamed our environment down, and unfortunately, because of energy efficiencies, we have eliminated that portion of the solar spectrum that we considered wasteful because we, it, it provided no visible light, and, uh, wasteful because it heated up our environment. And so we've actually intentionally eliminated that type of light from our environment. And, and so what's, what's funny is, um ... It's not funny, but it's just kind of, it's strange, is n- now we have these devices that give us that back, and the results are astounding, right? And people are, like, incredulous. Like, "Why would this light panel make me so much more ... Why are the studies showing this?" And I just have to think back, you know, 300 years ago. Imagine if we were sailors on a British ship, and, um, and, you know, w- I'm watching your ... and my gums bleed, and people are falling apart and dying, and someone comes to us and say, "Hey, you see this lemon? All you gotta do is eat this lemon, and you're gonna be so much better." We're like, "How could that possibly be? How could eating a lemon make us better?" But, you know, I like to quote Robert Fosbury, who, who first said this to me. He said, "You know, Roger, lack of infrared light is the scurvy of the 21st century."

   3. RCDr. Rangan Chatterjee38:26

      Wow. Yeah, it's, it's very profound when you put it like that. I, I wonder, Roger, how much do you think, if we take a step back and look at how many of us modern humans are living, as you've said, 92, 93% of our time is spent indoor, and therefore you and I both see this huge interest in health. People feel sick, they feel tired. They're wanting advice on how to live healthier lives. And let's take nutrition, for example. There's obviously many debates over the best diet for people to have, and some people seem to feel that they have to partake in quite restrictive diets sometimes in order to feel well.

   4. RSDr. Roger Seheult39:14

      Yeah.

   5. RCDr. Rangan Chatterjee39:15

      And I've seen that with patients. Sometimes actually it really works. You know, they cut out certain things, and it actually really does help them. But if we're trying to take this big picture view, I just wonder, if we're missing these natural signals that our biology has been wired to get for tens of thousands, hundreds of thousands of years, maybe the reason we're having to restrict our diets or, you know, take all this effort over our health is because we're missing this crucial macronutrient, as you say, infrared light.

   6. RSDr. Roger Seheult39:51

      Oh, yeah.

   7. RCDr. Rangan Chatterjee39:51

      We're missing infrared light-

   8. RSDr. Roger Seheult39:52

      Yeah

   9. RCDr. Rangan Chatterjee39:52

      ... so therefore we're having to compensate. And then I guess going one step further, we often talk about the blue zones, and I know there's some, you know, controversy over the blue zones around some of the literature, some of the research, but nonetheless there do appear to be these areas around the world where people have high rates of longevity compared to their surrounding areas. And everyone's talking about diet and community and their movement-

   10. RSDr. Roger Seheult40:21

       Yeah

   11. RCDr. Rangan Chatterjee40:21

       ... and their low stress, which of course are important things. But I bet if we look at those, uh, populations, they're also spending a ton of time outside.

   12. RSDr. Roger Seheult40:32

       Yeah.

   13. RCDr. Rangan Chatterjee40:32

       And they're in warm climates, a lot of them. I know Iceland isn't technically a blue zone, and I know they've got high rates of longevity, but a lot of the high longevity hotspots are in warm areas where people will naturally spend more time outside. So when you start to try and put it all together, it does start to converge on this idea that we might be missing one of the most important ingredients for health, and it's sitting there right under our noses.

9. 41:00 – 49:00

   Beyond sunlight alone: the eight pillars (NEWSTART) and a systems view of chronic disease

   1. RSDr. Roger Seheult41:00

      Yeah. Uh, w- where do we begin? Um-

   2. RCDr. Rangan Chatterjee41:02

      [laughs]

   3. RSDr. Roger Seheult41:03

      Look, we, we as human beings are a complex machine, and we intuitively know that the good care of a complex machine is not monolithic.

   4. RCDr. Rangan Chatterjee41:14

      Yeah.

   5. RSDr. Roger Seheult41:15

      If we have an automobile that we cherish, taking care of that automobile is not just about putting the right octane fuel in the tank. You also have to change the oil. You also have to change the air filter, rotate the tires, et cetera, et cetera. And the, and the total care of that automobile is going to allow it to run for a long time. And I can sit here and talk to you about sunlight, but sunlight is really only one of the eight laws of health that I like to talk about. Um, nutrition is one of those. So we do need to put the right things into our, into our body. Exercise is another one, as you mentioned. Uh, water is another one. So the free use of water is, is important in terms of filtering things, but not just the internal use of water, but also the external use of water. Water's a very, has a very high specific heat, which means that it can absorb heat, um, and raise the temperature very little, but it can also do the opposite. It can give off a lot of heat and still keep its temperature. And so because of that property, you're able to use it to elevate body temperature in certain situations when the body needs help to do that. That's a, that's another discussion. Sunlight is just one of those laws of health that we are talking about. What are some of the other laws of health? Temperance, not eating, uh, too much, a- avoiding alcohol, smoking. Uh, as a critical care physician, I see the results of the abuse of some of these drugs. Uh, air, fresh air. People believe that fresh air, the best type of air is air that is just-nitrogen and oxygen. And I, I can tell you, uh, the best actual type of air is not only oxygen and nitrogen, but also some of the phytoncides that come off of trees-

   6. RCDr. Rangan Chatterjee42:57

      Mm-hmm

   7. RSDr. Roger Seheult42:58

      ... that actually have been shown to improve our immune system. So walking out in nature. Um, there's also good bacteria. Just like there's good bacteria for our gut, there's also good bacteria in the, in the air that actually can help, uh, suppress infections. So this is science that is looking at, you know, what is really good air. The best type of air is the air that you find outside, and as I mentioned before, Florence Nightingale seemed to see that, uh, empirically with her patients. And then finally, uh, the last two would be rest, so not only good sleep and, uh, the ability to rest, not only nightly, but also taking a break every seven days and unwinding and basing yourself, uh, once again on the values and the core values that you have, and being able to think about things that you're not allowed to think about during the week because it's, it's, it's a, such a high-stress environment that it's good to stop. It's good to sort of after you're swimming under the water for six days to pop up and look around and see where you are and where you're going in life, and to, to, to take restock of that. That's really important. And then finally, the last, uh, law of health, and look, we, we've got good research on this, and it's not, i- it's, it's out of the sort of the... A lot of people consider this out of the scientific realm, but faith, uh, has been well shown in multiple scientific studies to actually have a benefit above and beyond community. So actual, you know, coming together, worshiping. This really has a strong focus on purpose. I know a lot of people, um, kind of shy away from this, but if you, if you're open to it and you look at the research, the research is there. And what I've found is not all, but most of the chronic diseases that we see today and that I have to treat, and I see them at the end of their lives in the ICU, is the manifestation of some violation of these eight laws of health. And if... A- and I'm, I'm not against using medications. Look, uh, when people are dying in my intensive care unit, I have to save their life. There's no amount of, of natural remedies that's gonna take care of someone who's dead. We have to save their life. We have to use medications. We have to do the best that we can. But if I don't redirect them after we've saved their lives and show them where their illness has come about from a violation of one of these eight laws, I'm not really doing anything for them. I'm just sort of delaying the inevitable. If you, if you want to concentrate, and someone's out there listening to this podcast and they're saying, "Look, I'm tired of being sick. I'm tired of being ill. I'm tired of having chronic disease, and I really wanna make a, a change," what I would do is, is put out these eight pillars of health. And these are not new. These have been around for some time. Um, in fact, there's a university in, just outside of Sacramento called Weimar University that's actually put these together in a mnemonic called NEWSTART, N-E-W-S-T-A-R-T, nutrition, exercise, water, sunlight, temperance, air, rest, and trust. And put those out and, and look in your life, look back on your life, look where you've been, and see where you might be violating those laws of health. And, and those are the areas that I think we can improve on. What I think is essential, what I like to talk about and get into the evidence for, 'cause I'm sure people listening to this saying, "Okay, give us the evidence," is that, is that first, is that S right there in the middle, and that's sunlight. And I believe, you know, it's just one of the eight laws of health. If you keep it, it's still possible to mess up on the other. What you really need, to use that car analogy, is all of those eight cylinders really firing and, and, and, and firing to get the real power of the V8 engine that you need in your car. Um, all of those really need to be looked at and, and addressed.

   8. RCDr. Rangan Chatterjee46:43

      Yeah. Yeah, I love that. I mean, I love the passion there, Roger. I love the analogy with the car, because that's it, isn't it? Right? You're only as good as your weakest link. So you can-

   9. RSDr. Roger Seheult46:54

      Yeah

   10. RCDr. Rangan Chatterjee46:54

       ... nail everything in your car, put in the right petrol, you know, tune up the radiator, whatever it [chuckles] might be. I'm not a mechanic, okay? Uh, so, but if your back rear tire is flat, it doesn't matter. Like-

   11. RSDr. Roger Seheult47:09

       Right

   12. RCDr. Rangan Chatterjee47:09

       ... you can do all that. You can keep spending more money on petrol or whatever it might be. That's gonna be holding you back, and I guess you're drawing an analogy saying, "Hey, listen, maybe you, you're nailing your nutrition. Maybe you are getting 10,000 steps a day, but maybe that's indoors on a treadmill," right?

   13. RSDr. Roger Seheult47:26

       Exactly.

   14. RCDr. Rangan Chatterjee47:26

       Maybe the weak link at the moment is your lack of time outside. Now, we also have to acknowledge that going outside is free, okay? [chuckles] It's not like you have to do anything, uh, or, or buy anything. Of course-

   15. RSDr. Roger Seheult47:43

       Yeah

   16. RCDr. Rangan Chatterjee47:43

       ... some people's lifestyles and their jobs make it harder for them to do it as much as they might want to, but at its core, you're talking about something that is completely free of charge, which I think is absolutely worth remembering.

   17. RSDr. Roger Seheult47:58

       Yeah.

   18. RCDr. Rangan Chatterjee47:58

       I wanna dive into those eight pillars for sure, and I'm very interested in some of those ones at the end there, including faith. But just going back to sunlight-

   19. RSDr. Roger Seheult48:06

       Yeah

   20. RCDr. Rangan Chatterjee48:07

       ... again, or, or natural light, I guess. On your YouTube channel, which is fantastic, on MedCram, you've, you've done so many videos on light and, you know, gone through various trials as to when a human being exposes themselves to certain doses of infrared light, you can have all kinds of benefits on your health. So from the top of my, you know, memory, I can remember one study on vision, uh, one study on blood sugar-Okay?

   21. RSDr. Roger Seheult48:37

       Yeah.

   22. RCDr. Rangan Chatterjee48:38

       Everyone thinks blood sugar's just to do with foods, and occasionally I'll try and persuade them it's also to do with stress, but there's also research, isn't there, showing that actually our light exposure influences our blood sugar? So can you just go through sort of top line of some of these papers? Because it really helps build the case to people as to why exposing ourselves to light is so important.

10. 49:00 – 54:10

    Key trials and the abscopal effect: vision, glucose control, and whole-body signaling

    1. RSDr. Roger Seheult49:00

       Yeah. So this is the part that I really love because once people start to see the studies, then they start to sit down and, uh, realize that this is not, uh, hyperventilation. So randomized controlled trials are the top level of evidence that we have. It, it gets rid of a lot of the confounders, and now it's starting to come out that we have these trials that show this. So again, Glenn Jeffrey's study showing that people that were exposed to infrared light, um, in, at, uh ... not even at their head, just in their thorax, showed that there was an improvement in the mitochondria when this was given in a randomized fashion in the eye. So these cones and, uh, in the eye, in the retina, look at blue light, green light, and red light, and they are extremely dependent on energy from the surrounding mitochondria in the cell, in these cones. And to the point that as these people get older, their ability to distinguish different types of red, different types of green, is limited by the amount of energy output from the mitochondria. When Glenn Jeffrey exposed them in a randomized fashion to 850 nanometers of light, he was able to demonstrate that the threshold for that, uh, um, colorblindness significantly dropped, uh, beyond any kind of, uh, understanding or, or confounding, that in fact this was actually working. So peer-reviewed, published in Nature Scientific Reports.

    2. RCDr. Rangan Chatterjee50:22

       You said 850 nanometers of light. Just to be clear so everyone's following this-

    3. RSDr. Roger Seheult50:27

       Yeah

    4. RCDr. Rangan Chatterjee50:27

       ... that is in the invisible range, right? So we can't see this-

    5. RSDr. Roger Seheult50:33

       Correct

    6. RCDr. Rangan Chatterjee50:33

       ... okay? But it's that infrared range. And you also said something that, um, I think is worth highlighting. The light was being shone on their thorax, yet it was, it was having an impact in many areas, including their eyes. And I think in one of the videos, you spoke a- about this being called the abscopal effect, how mitochondria can communicate within the body. So can you speak to that?

    7. RSDr. Roger Seheult50:56

       Yeah.

    8. RCDr. Rangan Chatterjee50:56

       Because that is super interesting.

    9. RSDr. Roger Seheult50:58

       Yes. So we, [laughs] we know that mitochondria can communicate not only with each other within the same organ, but can also communicate in different organs of the, of the same human body. Um, in fact, we actually have seen mitochondria floating, free-floating around, not even in a cell, but floating around in the blood. So there's a lot of things that we don't understand.

    10. RCDr. Rangan Chatterjee51:20

        Mm.

    11. RSDr. Roger Seheult51:21

        But what was clear here is that it is possible to get the benefits of sunlight in parts of the body that are not being directly exposed to the sun in the another part of the body. That was what was really clearly shown here in this study.

    12. RCDr. Rangan Chatterjee51:36

        Yeah. Absolutely incredible. What's quite interesting is that I'm really fascinated at the moment with vision and whether it's possible to improve our vision and improve our eyesight. And, you know, recently I covered this on a podcast with someone called Dr. Bryce Applebaum, and I've really been thinking about this idea that, you know, our modern lives, meaning that many of us are just constantly being exposed to just near vision, whereas we've evolved out on the plains where we could actually look out into the distance and-

    13. RSDr. Roger Seheult52:09

        Yeah

    14. RCDr. Rangan Chatterjee52:09

        ... you know, spot the predator far away. And, you know, current research is suggesting that by 2050, 50% of the world's population might have myopia and therefore need some form of glasses or whatever. But there are so many case reports out there which are, are absolutely convincing me that the more time we spend outside, the better multiple aspects of our health. And of course, this study showed specifically-

    15. RSDr. Roger Seheult52:32

        Yeah

    16. RCDr. Rangan Chatterjee52:32

        ... how infrared light exposure can improve certain aspects of our vision.

    17. RSDr. Roger Seheult52:37

        Yes. A- and, and vision is, of course, very important, and it's what Glenn Jeffrey does because he's a professor of ophthalmology. But realize that it, it ... the reason why there was improvement in vision in that study was because that's what he was testing. We've looked at, uh, in other studies, uh, multiple other aspects. So people have issues with cardiovascular disease, cancer. Let's ... I mean, the data is there for that, uh, as well. He also, by the way, checked blood sugar and, as we talked about already, there was a 27% reduction in blood sugar after a glucose tolerance test. He published that as well.

    18. RCDr. Rangan Chatterjee53:11

        That was from red light exposure, wasn't it?

    19. RSDr. Roger Seheult53:13

        Yeah. 670 in that case, red light exposure. So there seems to be this red infrared area, the near-infrared, where a lot of these benefits are occurring, yes.

    20. RCDr. Rangan Chatterjee53:23

        And, and I, I'm sorry to just keep clarifying the terminology, but I think these terms sometimes people find confusing. When you say near-infrared, w- what exactly do you mean by that?

    21. RSDr. Roger Seheult53:35

        It's, it's, uh, it's very, uh, human-centric. So near-infrared is closer to the s- to the visible spectrum. So it's that type of infrared that's just beyond red.

    22. RCDr. Rangan Chatterjee53:45

        I see. Okay. Okay. Then if we just zoom out to practical things that we can do, okay? Just, just through the lens of infrared light at the moment. Of course-

    23. RSDr. Roger Seheult53:55

        Yeah

    24. RCDr. Rangan Chatterjee53:56

        ... the best case scenario is that we spend more time outside. You're saying we don't have to spend all day. You're saying these 15 to 20-minute bouts, maybe two to three times a day if we can, gives us that exposure, okay?

    25. RSDr. Roger Seheult54:09

        Yeah.

11. 54:10 – 1:03:30

    When to use red light panels vs the sun: winter benefit, office studies, and a COVID hospital trial

    1. RCDr. Rangan Chatterjee54:10

       But of course, some people are still gonna struggle to do that, and red light panels are probably one of the hottest things in wellness over the past few years. I think a few years ago there was skepticism in quite a lot of areas about the benefits. I think that skepticism is starting to change now as more and more research comes out. What is your view on red light panels and how they can help us with our health?

    2. RSDr. Roger Seheult54:40

       I think they are a tool that can be used if it's impossible to get sunlight. I'll, I'll give you some data about that, uh, understanding. There, uh, Glen Jeffrey, once again, did a study, uh, and it hasn't been published, it's in review right now, where he took people that were in a LED environment. So in an office environment lit with LED bulbs. This is a very common scenario. It was actually at a building there at UCL. And what he did was he, in a randomized fashion, put a 60-watt incandescent light bulb at each desk and, um, and turned it on in a randomized fashion, and did a very similar, uh, test that we just talked about where we measured the color blindness in these, uh, subjects. And what he found was that the presence of the incandescent bulb alone at their desk was enough to improve their vision. In other words, that incandescent bulb was giving them enough of the infrared light to improve their vision so that they actually outperformed those people that were sitting at their desk with just an LED environment. Now, there was another study that was done where it was very similar to this, where they had, uh, ag- again, in an office situation, LED bulbs. And what they did was at each of these desks, they placed a, um, a, a, a red light panel, okay? Similar to the one that we're just talking about, to see whether or not it improved general wellness. And they had a number of, of factors, wellbeing. Uh, they had a number of endpoints, which I, uh, escapes me at this moment, but there were definite, uh, a priori endpoints in that study. This is something that they found that was very interesting, and it, and it's, it's the reason for my placing sunlight above LED, um, panels, uh, red light panels, I should say. What they found was this: They found that there was an improvement in wellness in those subjects that had the red light panels at their desk, but only in the wintertime.

    3. RCDr. Rangan Chatterjee56:50

       Hmm.

    4. RSDr. Roger Seheult56:51

       So in other words, they did this, they did this e- experiment throughout the year. They only found a statistical benefit, they only found an, a, a effectiveness when they did it on subjects in the wintertime. So what does that tell me? It tells me that these things work when there is a paucity or a, a, a reduction in the amount of sunlight that someone is getting. So this brings up the paradox. The paradox is, is that sunlight is beneficial, but for any given individual, its effects are the best, are the most, are the most important, particularly and precisely at the time of year when it is the least available. And so if that becomes an issue for someone, if they are not able to get outside because of their job or because of their abilities, and they're not able to get that light in the wintertime, we'll talk about some research about why this is really important, then, then yes, definitely. And look, I'm an ICU physician. I take care of patients that are too sick to even move out of their bed. So there is a need for this. But if you're a healthy individual that can be mobile and do... and you're asking the question, "Should I invest money in a red lamp or a, uh, or a panel, or should I just go outside into the sun?" To me, the answer's pretty clear.

    5. RCDr. Rangan Chatterjee58:09

       What if someone says, "Roger, that's great, but I live in a place where six months of the year it's cold, dark, rainy, and cloudy. And even with the best intention, and even with you sharing all this wonderful research with me, I know what I'm like in the winter. I'm unlikely to motivate myself to go out when the weather is not so inviting." For that individual, would you say that, yeah, look, a bit like a supplement maybe, a food supplement?

    6. RSDr. Roger Seheult58:38

       Yeah.

    7. RCDr. Rangan Chatterjee58:39

       You know, if you're, if you're... I guess if you're spending loads of time out in the sun all the time and, and you're topped up with, uh, vitamin D from the sun converting, uh, that vitamin D in your body, then you're probably gonna have very limited benefit from vitamin D supplements 'cause you, you're already topped up from your lifestyle. And I guess it's the same principle here, isn't it? It's like if you're low, if you're light deficient, then certain things like these red light panels can perhaps be useful. Do you see it like that?

    8. RSDr. Roger Seheult59:10

       Yeah, absolutely. So one of the things that I learn as a physician is you can learn everything in the book, right? But you've gotta meet and understand the patient that's in front of you and meet them where they are and try to figure out what's the thing that's gonna work the best in their particular situation. So you've described a situation where somebody is likely not gonna be getting outside in the sun, and in this case, a panel is gonna be certainly better than nothing. Uh, look, there's, there's several studies that have shown that the type of, this type of light use is beneficial. The one that comes to mind, uh, off the top of my head is a Brazilian study where they looked at COVID patients that were admitted to the hospital. And, um, you know, let, let me just put a backstory on this. People who have COVID are very much in, uh, oxidative stress. We know that very clearly because of the ACE2 receptor. We know that their mitochondrial, uh, are damaged. We know that a lot of the issues with the, the, with the blood vessels in the lungs is that the covering of those blood vessels become so damaged because of oxidative stress that they release these, uh, factors that can cause blood clots to occur. This is all related to oxidative stress, and if you can mitigate that oxidative stress with infrared light, which is exactly what happens, then there's a hope that, that actually, uh, you could prevent a lot of the, the detrimental effects of COVID and hospitalization. So these group of researchers in Brazil did an amazing study. They actually made a light panel that you could wear. It was a jacket-It had LED lights on the inside, and it was, uh, transmitting at 940 nanometers, so that's still in the infrared spectrum, near-infrared spectrum, just past the red light. It was wonderful because you, you didn't have to blind these people because you can't see the light anyway, right? These are just LED bulbs. And, uh, they put it on all of the subjects. There was about 30 subjects, and randomly they would turn them on. Listen to how often they got it. 15 minutes a day, once a day. That was it. We're talking about exposure to infrared light for just 15 minutes, one-five. And the, the intensity of the light was 2.9 milliwatts per square centimeter. That's, that's at or below the amount of light that you would be getting from the sun, okay?

    9. RCDr. Rangan Chatterjee1:01:33

       Mm-hmm.

    10. RSDr. Roger Seheult1:01:33

        Uh, in, in that particular wavelength of infrared light. So very... Not very high. So we're talking about not very high light for 15 minutes a day. Not much. So after seven days, they did it for seven days, they compared these two groups. It was incredible. Every single endpoint that they looked at was statistically significant. Every single one of them. The people who got the... The- these were people that were admitted to the hospital that were not sick enough to be in the ICU, but sick enough to be admitted requiring oxygen, okay? COVID patients. They, their oxygen improved faster. They were able to take a deeper breath faster. They were able to sustain their breath faster. Their heart rates improved faster. Their respiratory rates improved faster. The, the cells in their immune system that were responsible for fighting the virus, instead of going down in the control group, they went up and actually improved. But the biggest number out of this whole study was instead of the average hospitalization for the COVID patient being 12 days, it was cut by four days down to eight days. These patients were out of the hospital four days faster by just getting 15 minutes of essentially what was artificial sunlight.

    11. RCDr. Rangan Chatterjee1:02:51

        I mean, that is utterly incredible, right? Utterly incredible, because we don't think about light as a nutrient like that, as a, as a, as a drug, a- as a medicine to use to increase the rate of discharge, the speed of discharge, right?

    12. RSDr. Roger Seheult1:03:09

        Yeah. Uh, and th- this is data that we've had for a long time. I mean, people who are closer to the window... Th- there's, there's numerous studies. So MICU patients, post-op patients, SICU patients, cardiac patients, they've done the research on all of these. The ones that are closer to the window, or if the window is bigger, they are discharged from the hospital faster.

12. 1:03:30 – 1:07:10

    Windows, low‑E glass, and modern building tradeoffs: why ‘near a window’ isn’t the same as outdoors

    1. RCDr. Rangan Chatterjee1:03:30

       Can I ask on that? So that's interesting, 'cause we know, for example, if we wanna make, uh, vitamin D, we know that we can't just be getting that sunlight through the window. We have to actually be outside with the sunlight on our skin.

    2. RSDr. Roger Seheult1:03:44

       Yeah.

    3. RCDr. Rangan Chatterjee1:03:45

       How does that relate to those other components of light? You know, the, the, the infrared light, um, for our circadian rhythm, all, all these kind of inputs from light. Because, you know, what happens if we're behind a window and not outside? Are we getting some benefit still or not really?

    4. RSDr. Roger Seheult1:04:03

       We are getting some benefit still, but not the full benefit of going outside. So that's why I'm such a proponent for leaving the structure and going outside. So here's, here's the issue. A lot of these studies that were done looking at hospital windows were done decades ago-

    5. RCDr. Rangan Chatterjee1:04:21

       Mm

    6. RSDr. Roger Seheult1:04:21

       ... long before we started instituting windows being put into buildings that had what we call low-E glass. This is glass that is specifically designed to not allow infrared light into the building because that heats up the environment-

    7. RCDr. Rangan Chatterjee1:04:37

       Of course

    8. RSDr. Roger Seheult1:04:37

       ... and increase the costs for air conditioning. Um, so it's unclear how much of that would be true in an environment where there is the blocking of that infrared light. Now, I don't know in England or in, in the UK, for instance, how often that kind of glass is used. I can tell you here, where I live in Southern California, it's mandatory. Uh, it's because w- we have a problem here in California with, with homes being too hot, not with being too cold. So we have gone to one extreme to prevent the overuse of air conditioning. I could see, though, very easily in higher latitude areas where the sun actually produces heat in a g- in a good way, so you don't have to heat the house, they may not mandate that as much. But this is still an issue. One of the ways you can find out if you're in your home, whether or not your glass is a low-E glass or not, if it's glass that's more than 50 years old, the chances of it being that type of glass are very low. But another way is just simply standing in the window when the sun is coming through, and if you can feel the warmth of that sun coming through that glass, you are-- your chances are that that is not a low-E glass and there's plenty of infrared light coming through. Although, not as much as if you were to go outside.

    9. RCDr. Rangan Chatterjee1:05:55

       Sorry to interrupt. To make sure you are taking action after watching this video, I have created a free special guide to help you improve your sleep and reduce fatigue. Now, in my clinical experience, most people who are struggling to sleep are doing something unconsciously in their day-to-day life that is negatively impacting their ability to sleep at night. So in this free guide, I share with you five of my very top tips, tips that I have seen transform the lives of many of my patients. So if you wanna get hold of this guide, all you have to do is click on the link in the description box below. Yeah, it's interesting that as we're getting more advanced in many ways as humans, so we can make this, you know, high-tech glass that protects us and, you know, means we have to, uh, use less-... energy to heat or cool down the house.

    10. RSDr. Roger Seheult1:06:53

        Yeah.

    11. RCDr. Rangan Chatterjee1:06:53

        We're also doing it at a huge cost to human health, and there's so many more analogies like that across society aren't there? As we've become more comfortable in our lives, as we've tried to make our lives more comfortable, actually our biology has really, really suffered. It's fascinating.

13. 1:07:10 – 1:19:04

    Sunlight risk-benefit and skin protection: UK Biobank data, melanoma nuance, and daily ‘solar rhythm’

    1. RSDr. Roger Seheult1:07:10

       Yeah. You know, you, and you know, um, Dr. Chatterjee, there's a, there's a study that just came out last year that I think, um, uh, many of your audience who a- who's living in the UK would be very interested in. This was done out of the University of Edinburgh, and it was, uh, a dermatologist-

    2. RCDr. Rangan Chatterjee1:07:25

       Mm-hmm

    3. RSDr. Roger Seheult1:07:25

       ... by the name of, uh, Dr. Richard Weller up there in Scotland, and he looked at, um, the data bank, which is a wonderful data bank, by the way. It's the world's envy. It's the UK Biobank, um, where we can get a lot of papers out of that, out of those, um, out of that data and statistics. What he did was he looked at I think it was about 3 to 400,000 subjects, both men and women, living in the UK, and he looked at two things. Number one, he looked at the use in solariums. Obviously, you know that better than a lot of, uh, our, our American friends here, over here, what, what a solarium is. But obviously it's, for those that don't know, it's, it's basically these extensions off of the home that are covered in glass where you can go out and, and be exposed to a lot of the light. So obviously by definition, this is light coming through a window. But he also coupled that with shortwave radiation. They have the ability to look particularly in the UK and over a, a period of a year decide how much shortwave radiation is coming to that area, and what I mean by that is ultraviolet light, essentially. So this is ultraviolet light we're talking about now, not infrared, but of course, when you're out in the sun, ultraviolet light is associated with infrared light as well. So all of this is coming as a package deal. Here were the findings. He found that as solar radiation went up, as solarium use went up, what went down was all-cause mortality, cancer mortality, cardiovascular mortality, um, and also non-skin cancer mortality. The big question, though, and he- that he had as a dermatologist is, well, what about melanoma? And in that study, which was a very large study, they looked at what happened to the incidence of melanoma, and while the numbers slightly went up, it was, it, it was unclear whether or not the numbers went up as a result of just by chance or whether it was statistically significant. So what we would say is, is that we could not say with greater than 95% assurity that there was any rise whatsoever in melanoma incidence in a population in the UK. Uh, and I think that's actually very important because what we have now is we have definite evidence that exposure to sunlight, and we know this from the Swedish study that was published in 2016, we know that sunlight exposure reduces the risk of all-cause mortality. It's associated with a reduction in all-cause mortality. It's associated with a reduction in cancer mortality. It's associated with a reduction in cardiovascular mortality. And yet on the other side of this, we're not seeing a dramatic increase in the incidence of melanoma, which of course is a deadly, uh, skin cancer. And so Richard Weller understood this. He actually wrote a, a, an editorial, actually a review to the, um, to a major dermatological, uh, journal called the, the Journal of Investigative Dermatology, where he published a piece called Sunlight: Time for a Rethink. And he, he mentioned in that review that a number of major organizations, dermatological organizations, even in Australia of all places, where skin cancer is a, is a real issue, um, and he's showing that those organizations are now coming to the conclusion and they're realizing that avoidance of the sun is a double-edged sword and that we need to tailor our recommendations with the understanding that there is a risk-benefit ratio. I think that's a very good first step. What I, where I'm coming from on this is that I believe you can have your cake and eat it too. Uh, it's possible for you to get the benefits of sunlight exposure, and if you're concerned about skin cancer or skin damage, because of the nature of infrared light and its ability to penetrate through clothes and its ability to reflect off of trees and be very high in your environment, if you are that type of individual, you could go outside on a sunny day, you could sit in the shade around trees, you could cover up with a, a layer of clothing, wear long sleeves, even wear a wide-rimmed hat, and I believe that you could get the benefits of infrared light in that environment much, much better than you would inside even with a window.

    4. RCDr. Rangan Chatterjee1:12:01

       Yeah. It's, i- it's really quite remarkable when you start thinking about what we've been told to fear in society and where that has come from, right? Because until relatively recently, this idea that you must fully cover up in sun cream before you go out in the sun, it wasn't really a thing. And as you say, there, there have been some unintended consequences of that. Of course, no one's saying go out there and get sunburnt.

    5. RSDr. Roger Seheult1:12:34

       No.

    6. RCDr. Rangan Chatterjee1:12:34

       At the same time, Roger, I don't know if you've seen this. I've seen this in a patient population, uh, in the past for sure, and many colleagues of mine who practice in a way to me have also seen this, that often people who used to find that they would burn a lot, when they change their lifestyle and often change-

    7. RSDr. Roger Seheult1:12:53

       Yeah

    8. RCDr. Rangan Chatterjee1:12:53

       ... their diet quite dramatically from ultra-processed foods to more minimally processed whole foods-They find that they burn less, right?

    9. RSDr. Roger Seheult1:13:02

       Yeah.

    10. RCDr. Rangan Chatterjee1:13:02

        Which-

    11. RSDr. Roger Seheult1:13:02

        Yeah

    12. RCDr. Rangan Chatterjee1:13:03

        ... is, you, you hear it enough times, you go, "There is something going on there." And then the follow-up question or the follow-up thought for me, which really fits with the theme of th- this entire conversation, is that maybe the reason that the sun appears to cause problems for some of us is because we're so sunlight deficient. Maybe if we weren't so deficient as a society, maybe if we were all getting a couple of hours of natural light exposure every day, maybe we'd have to be less worried about those potential, uh, downstream implications. Do you know what I mean? There's quite a lot to unpick there, isn't there?

    13. RSDr. Roger Seheult1:13:41

        There is. Um, there is a lot.

    14. RCDr. Rangan Chatterjee1:13:43

        [laughs]

    15. RSDr. Roger Seheult1:13:43

        Um, and, uh ... Well, where do we begin? So look, if we look at just what happens in a day when the sun comes up in the east and then sets in the west, you're ... Because the sun when it comes up has to cut through so much of the atmosphere, you're getting primarily infrared-rich light and ultraviolet-poor light. What is that doing? There's evidence that that light when it's going into the, the skin and into the body is causing the production of melatonin in the cells in the skin and in the body. This is, this is the same substance that's produced from the pineal gland right before you go to sleep, but it's a very powerful antioxidant, probably produced on orders of magnitude higher, uh, than in the pineal gland. But it's produced locally, and that melatonin is being built up, getting ready for the onslaught of the day. And then when the sun goes up, 10 o'clock in the morning, 12:00, 2:00, 3:00, 4:00, that whole area there where ultraviolet radiation is coming down to do, you know, obviously some good, right? It's producing, uh, vitamin D in the skin, but remember the skin has been bathed with this melatonin, getting ready for the onslaught. And then as the sun starts to go down, you've got melatonin once again being produced to mop up any damage, any kind of, uh, mutations that have occurred, antioxidants. And so it, the, the entire cycle of the sun as it's going from the east to the west has built in because of the atmosphere and because of what it does in the human body, almost like a built-in, uh, protective, uh, um, progression in the skin so that, uh, the damage doesn't occur as mu- as much. You can think about what might happen if you were inside the whole day and only went out at noon.

    16. RCDr. Rangan Chatterjee1:15:29

        Yeah.

    17. RSDr. Roger Seheult1:15:30

        Which is actually what I try to do, but I, I try to stay in the shade, and I do get out more o- on the weekends to make sure I build up what some people call that sort of solar callus where, you know, you've, you've used it and, and, uh, those things are in place. What you don't want is someone to all of a sudden who hasn't been outside to just go outside in ultraviolet light and, um, and ultraviolet-rich sunlight and, and get skin burned. Uh, that's, that's not at all what we wanna see. We wanna see rational, moderate sun exposure above and beyond what people are getting now, which is significantly less than what we were getting just even 30, 40 years ago.

    18. RCDr. Rangan Chatterjee1:16:11

        Yeah. As you describe that sort of path of the sun from east to west and the various wavelengths that we get exposed to throughout the day, it's an orchestra, isn't it? It's a symphony that, that ... It's, it's going on to prepare us and to get us ready for the next level of e- exposure, but we're missing that. We're sort of missing that whether we're indoor or lives. And then as you say, what often happens, it certainly happens in the UK, particularly after a long winter, you know, where the first day that it's sunny, people will literally go out all day after having had no sun, uh, all winter and then often become red or get burnt. And it's these-

    19. RSDr. Roger Seheult1:16:50

        Right

    20. RCDr. Rangan Chatterjee1:16:50

        ... kind of extremes, right, that could be causing the problems, whereas if we had that more low-grade solar exposure throughout the year, maybe that wouldn't happen. Maybe we'd build up that callus. We'd have, you know, that adaptation. The body would be used to it. And of course, we have to recognize that skin color and skin tone plays a role here, doesn't it? Because your skin tone and mine are very different because of our ethnicities. And therefore, we perhaps are gonna need different levels of sunlight in order to thrive.

    21. RSDr. Roger Seheult1:17:23

        Yeah. Let's think about what happened here. I mean, I think it's pretty well accepted that, uh, the human race originated probably near to the equator. I mean, there's debates about exactly where, but that would tell us that the original human beings were probably darker skinned. And as a result of that, um, uh, it was probably a result of the fact that sun was coming in at the equator pretty strong. But as these populations started to migrate, think about what happened, and what you saw is that these populations that start to move further and further north or south away from the equator, they start to develop lighter skin. Now, why would the body n- find the need to do that? It's, I feel, because there is the import- such ... There's ... The body places such an importance on light at those latitudes that it actually needs to pull back that melaton- or melanin, and it needs to lighten the skin so that it can get the beneficial effects of vitamin D, um, infrared light, of course, to that degree. But, but clearly you can see here that there is an adaptation that is occurring within the human species as you move away from, uh, this type of bright equatorial sun that you often get.

    22. RCDr. Rangan Chatterjee1:18:38

        What was interesting in the study you mentioned before of Glenn Jeffrey in the offices where they've got LED lights overhead, and I think you said that some of the participants had an incandescent bulb put in front of them, right? So nothing else changed.

    23. RSDr. Roger Seheult1:18:55

        Right.

    24. RCDr. Rangan Chatterjee1:18:55

        And just from getting that more broader exposure to the, all these different wavelengths of lights, they started to get better health outcomes, right?

    25. RSDr. Roger Seheult1:19:04

        Yeah.

14. 1:19:04 – 1:38:02

    LED lighting, screens, and ‘bright nights’: why light timing drives mortality, sleep, and child health

    1. RCDr. Rangan Chatterjee1:19:04

       That's quite interesting because-Incandescent bulbs are getting harder and harder to get hold of

    2. RSDr. Roger Seheult1:19:10

       Yeah

    3. RCDr. Rangan Chatterjee1:19:10

       The laws are changing. What we're able to buy these days is changing. Can you just explain what LED lights are and what has been the consequence of more LED lights coming into our lives?

    4. RSDr. Roger Seheult1:19:24

       Yeah. So LED lights are basically... Well, let's back up and talk about incandescent. Incandescent bulbs are, um, basically taking electrical energy, converting it into a thermal, uh, energy using, uh, different types of metals and filaments, and it's creating a very broad spectrum of energy coming out of that bulb. So there is visible light, but there's also probably the majority of the energy coming out of that bulb is in the infrared spectrum, and there's also heat coming out as well. So that's, that was what was invented by Thomas Edison over 100 years ago, and what has happened is we've tried to improve on that, um, on that, uh, e- equation there. We've tried to improve on that, uh, invention by saying, instead of putting so much energy into this entire cacophony of wavelengths, since the purpose of a light bulb is to produce vision, why don't we concentrate all of that energy onto the visible spectrum and cut out the, quote-unquote, "wasteful", uh, amount of wavelengths? And so you have, um, light emitting diodes, which is the product of, of, um, uh, technology, and where you have a very exquisitely high energy efficiency, where almost all of the energy that's going in is being emitted as a visible light. Okay? So, uh, that is exactly what happens with LED bulbs. You can kind of manipulate the color on those and, and it really doesn't matter for the discussion that we're having because whether you have a, a high fidelity LED bulb, one that's more blue, one that's more yellow, it's irrelevant because in all of those cases, they by definition are going to be missing the infrared, uh, spectrum-

    5. RCDr. Rangan Chatterjee1:21:15

       Mm

    6. RSDr. Roger Seheult1:21:15

       ... that we would normally be getting. And so for the very first time in human history, human beings are now being exposed to light that only contains visible wavelengths and does not contain the infrared wavelengths. So whether it's the sun, whether it's a candle, whether it's a fire, whether it's a incandescent bulb, all of those always co-transmitted visible and infrared together. Now, why is that important? Again, we've already showed very clearly that infrared light is beneficial in terms of mitochondrial output of ATP, and if you look at the back of someone's retina and look at it under a microscope, you will see that the cones, and even the rods to some degree, are highly endowed with mitochondria. In fact, it's the one tissue of the human body that has the highest concentration of mitochondria, and the reason is, is because what the retina has to do is it has to convert photoelectric energy into neurochemical transmitters that send signals back to the brain, and that has to be done rapidly and rapidly updated so that the brain can know literally by the millisecond what it is that's going on in the environment. That takes a tremendous amount of energy. And so you have two components here in the back of the retina. You have the components that are sensing the visible light, and you have the components that are generating the energy so that those sensors can do their job. And obviously visible light is important for the sensors, but the non-visible infrared light is important for the energy generators. And so now what we have is a situation where we are essentially asking the retina to make bricks without straw. We're giving them visible light.

    7. RCDr. Rangan Chatterjee1:23:11

       Mm-hmm.

    8. RSDr. Roger Seheult1:23:11

       We're giving them a load to do work on, but we're not giving them the light that we have enjoyed for millennia, and now for the first time, that light that we're exposing our eyes to does not have that infrared light to support and to n- nurture the mitochondrial activity that is required. And so when you see these studies that Glen Jeffrey publishes where he's adding light bulbs to the environment, which are, uh, incandescent light bulbs which have infrared, or he's shining specifically infrared light into those people's bodies, um, as we talked about in the first study. What we're seeing, and you shouldn't be surprised, that now that we're supplying the nutrients to the energy producers, obviously these sensors can now work at a higher level, and the amount of in- of, of red color blindness, green color blindness, and blue color blindness is gonna drop significantly, which is exactly what it showed.

    9. RCDr. Rangan Chatterjee1:24:05

       What are these screens doing to the light spectrum that we're being exposed to?

    10. RSDr. Roger Seheult1:24:13

        Yeah. So the screens do have all sorts of light, and particularly blue. It's not so much the issue of whether there is infrared or not infrared, although that is a problem. Certainly you're not getting any infrared light coming from the screens. But the issue is, is when we're using the screens. So are we using the screens during the day or are we using the screens at night? And that comes down to a circadian issue. So use of light at night, whereas light is your friend during the day. We've spent the whole time talking about how the benefits of light are, and I-- we should put a caveat on that. You know, we should really say that all of these benefits will only occur if really you're doing it when the sun is up.If you start to expose the body to light when the sun is down, that has the opposite effect. It shuts down melatonin production in the pineal gland. It, uh, increases the risk of cardiovascular disease. It increases the risk of cancer. Um, we know that very well. Uh, we actually have very good studies that show this. There's actually recently a, a, a beautiful paper that was published in the proceeds of the National Academy of Sciences, and it's titled Dark Days and Bright Nights. And, uh, this was an amazing study if I tell you about it. Um, they put-- They, they gave everybody a watch with a light sensor on it, and they stratified everybody based on a Gaussian distribution, who were the people at a particular hour that were getting more than 90% of the light of the population, and who were the people that were getting less than 50% of the light in that population. And what they did was they compared them at every individual hour. So they had a graph, and it started at four o'clock in the afternoon, and it went to three o'clock in the afternoon the next day. And they said, at each one of these hours, "Okay, in this hour, at four o'clock in the afternoon, who are the people that had greater than 95% of the light exposure at that hour, and who are the people that had less than 50? Okay, we followed them now for, for 10 or 20 years. Who died? And what was the risk? What was the associative risk?" And so they showed it, and they showed that at four o'clock in the afternoon, if you're getting in the 95th percentile, 90 to 95th percentile of light coming to your body as detected by the watch, your risk of dying according-- uh, compared to the people who got less than 50% was less than one, okay? In other words, you had a lower risk of dying if you're exposed to light at four o'clock in the afternoon. Then they did five o'clock, six o'clock, and this trend continued all the way to about nine, 10, 11 o'clock at night, and then something happened. It jumped over one and went higher than one. In other words, people past 11, 12 o'clock at night who had greater than 90% of the light of that population compared to people who were getting less than 50 had an increased risk of dying at that time. And that continued until about five or six o'clock in the morning. Then it made a quick drop down below one, and now light, once again, was no longer a liability. It was now a benefit. It was a, it was an amazing study.

    11. RCDr. Rangan Chatterjee1:27:29

        So, so light is medicine depending on when you get that light. But one thing you said there, Roger, which I just wanna clarify, you're saying even at 10:00 PM and 11:00 PM, exposure to light can perhaps be helpful? Um, I mean, when you-- you're not recommending people necessarily get their laptops out at 11:00 PM and expose themselves to lots of blue light. I don't think we can take that conclusion from that, can we?

    12. RSDr. Roger Seheult1:27:56

        No, I, I, it-- The benefits were diminishing rapidly.

    13. RCDr. Rangan Chatterjee1:28:00

        Yeah.

    14. RSDr. Roger Seheult1:28:00

        And what, and what happened was it started to go above one by the time you hit, uh, 10 or 11. There's other issues that happen when you expose your eyes to bright light at night, and that is, is that it can delay your circadian rhythm, and, and that's a real problem. So, um, again, as they went from... Well, I didn't say this before, but I'll add this. As they went from 90 percentile and up to 80 percentile and up to 70 percentile and up, they looked at different graphs. The, the magnitude of the difference started to become diminished. So th- this study told me two things. It told me-- The first thing was, is that light can be a benefit or a liability depending on when it happens.

    15. RCDr. Rangan Chatterjee1:28:41

        Mm-hmm.

    16. RSDr. Roger Seheult1:28:41

        Okay? And then number two is, and this is really dear to my heart because as a critical care physician, sometimes I have no choice, but I have to go in and take care of patients at night, and I have to do night shifts. Uh, but what it told me was that, that, that magnitude of benefit and risk was diminished in both directions when the brightness of the light was diminished. So if I have to go in at night and I have to see patients, I'm gonna make sure that I'm in a dark room or it's, it's dimly lit, or I turn down the brightness as much as possible because that makes a difference. It's not an all or nothing. And so I do believe that that's important. For people who work night shifts, um, it's different if they are daytime people who occasionally do night shift. In that situation, night shift can be detrimental, um, versus people who are on night shift all the time and they continue that trend the whole time. Um, and it's really important that if they're gonna do that, that they make sure that even on their days off, they are continuing to maintain their dark-light cycle. And of course, there's some things that you have to do. You have to make sure that your, your room is completely dark when you're sleeping during the day, that there's no light coming in. Sometimes you have to use aluminum foil around the windows. You have to get some sort of bright light exposure, um, uh, during the night to make sure that your circadian rhythm is in line. And, uh, I'll say this here because this recently just came out. It seems as though what's very important in terms of minimizing the cardiovascular risk from doing nighttime work is that you do not eat at night. So this was a very elegant study that they showed that people who-- They took normal subjects. They converted them into night shift workers for the study, and they showed very elegantly that the best time to eat is actually after you're done with your night shift and you go home and you sleep, and you intermittently eat during your sleep time, and then go back to work and don't eat at all on your night shift because that confuses the peripheral clocks with the central clocks. Very elegant study. They were almost able to completely eliminate a lot of the metabolic problems, uh, seen with diabetes, for instance, and cardiovascular disease, uh, in terms of a short-term markers for surrogates in that study. So, um, since we're on that topic, I just thought I'd mention that.

    17. RCDr. Rangan Chatterjee1:31:00

        Yeah. Yes. Super interesting and very, very helpful, of course, to people who do work night shift.There's quite a lot of research now showing us, as you've just outlined, but, but many more papers, that the more light exposure we get at night, the worse our health outcomes. I think I've heard you talk before about a 2023 China study where they looked from satellites at how much light people-

    18. RSDr. Roger Seheult1:31:26

        Yeah

    19. RCDr. Rangan Chatterjee1:31:26

        ... were being exposed to, and the more light you were being exposed to at night, the greater your risk of all-cause mortality, uh, which was quite profound.

    20. RSDr. Roger Seheult1:31:36

        Yeah, exactly. The other thing about it, too, it's even, it's even, um, worse than, than that because what we're seeing in these cities where we're using LED bulbs to light up, I mean, it's, it's cheaper now to do it, right? Because you don't use as much electricity. You can leave it on all the time, and it's actually going to use up less electricity. The problem is, is that photosynthesis is dependent on visible light. It's, it's blue and red, somewhere in that area. Um, and so what you're seeing is, um, plants in the environment that are being subject to the light from LED bulbs outside are starting to become thicker, and interestingly, the insects that are supposed to eat these leaves on a regular basis to survive can't do it because it's too tough. And so what we're seeing is we're seeing a collapse in the populations of insects in these cities where they c- th- these insects are not able to eat any more food or, uh, less food because of the light on these trees. It's, it's things that you wouldn't even think about-

    21. RCDr. Rangan Chatterjee1:32:39

        Yeah

    22. RSDr. Roger Seheult1:32:39

        ... that there are complications when you disturb the natural rhythm of light in the environment.

    23. RCDr. Rangan Chatterjee1:32:46

        Yeah. Unintended consequences of humans taking over the planet. Uh, that, [laughs] that, there's another one. Um-

    24. RSDr. Roger Seheult1:32:53

        Yeah

    25. RCDr. Rangan Chatterjee1:32:53

        ... one of the things that has concerned me the most in terms of public health, but specifically children's health over the past years, is the introduction of screens into classrooms and in particular, the fact that a lot of kids now across the world have to do their homework in the evenings on bright screens. From all the research you've done and all your clinical experience, what is your perspective on that?

    26. RSDr. Roger Seheult1:33:27

        Yeah. It, it's not good. Um, so we know that people who are blind, because there is an interruption in the, from the retina to the back of the brain where the melatonin is produced, they have less, 30% less cancer rates. Um, and, and it could very well be because there's no amount of light at night that's gonna shut down their melatonin production because the nerves are severed.

    27. RCDr. Rangan Chatterjee1:33:53

        Mm-hmm.

    28. RSDr. Roger Seheult1:33:54

        And so what does this tell you? It, it sort of reinforces this idea that light at night, especially in individuals such as children who need to have more hours of sleep than we do, right? We can get by on, I mean, ideally, we should be getting seven to eight hours of sleep. For children in school, they should be getting close to nine or 10 hours of sleep a night, and so we're, you know, they're, they're the ones that are staying up late. I mean, I have kids who are in high school, and, uh, you, what you've just mentioned is exactly what is happening in their situation. They are expected to have... In some of, some of the classes, they're expected to have phones, um, to, to be able to complete the homework because there's something online that they have to do. In other of the classes, they're expected to turn in their phone before the class begins because the teacher doesn't want distractions. I think that's actually appropriate. But when they get home, a lot of these, uh, assignments are turned in on, on electronics.

    29. RCDr. Rangan Chatterjee1:34:49

        Yeah.

    30. RSDr. Roger Seheult1:34:49

        So it's almost like, it's like you can't even get into the game without having some sort of a handheld electronic device. Let's not even talk about the fact that, the fact that they have an electronic device now allows them much more ease to get on social media-
15. 1:38:02 – 1:57:26

    Action plan + evidence: morning outdoor light, SAD boxes, nighttime darkness, and the ‘green heart’ tree study

    1. RCDr. Rangan Chatterjee1:38:02

       So I bet there's been some practical things throughout the conversation, but I wonder if we could just really focus for the next few minutes on what are the things then you recommend people do to try and mitigate this?

    2. RSDr. Roger Seheult1:38:14

       Absolutely. I believe that people need to get outside in any way they possibly can. If they're concerned about direct sunlight damaging their skin, they can cover up. And to get outside and just sit, uh, or, or exercise if they want to in an outside environment for at least 15 to 20 minutes a day. The best time of day to do that would be in the morning time. And the reason for that is because you're killing two birds with one stone. Not only are you getting the benefits of infrared light, which are bountiful in the morning, but you're also getting the visible light into your eyes, and it's causing the, uh, benefits in terms of depression and of- also in terms of setting the circadian rhythm in order. So that's sort of a double whammy. I understand, though, that for many people, they cannot do that. And so for people who get up early in the morning and are not being exposed to the sun early in the morning and have to do it later in the day, that's perfectly fine. What I would recommend doing, especially at high latitudes, where you are there in the UK and also in Canada and, and, uh, parts of Europe, is to get something called a S-A-D box or a SAD box. Um, and what does this stands for? It stands for seasonal affective disorder. It's very inexpensive. You can probably get these for about 20 bucks online. And the key here is that it, it needs to be 10,000 lux, uh, giving visible light. It sits about 30 centimeters from your face, and you're in front of it for about 20 minutes a day. You can also buy glasses that can do something very similar that can put that kind of light into the eyes. This is not a substitute for going out in the sun because-

    3. RCDr. Rangan Chatterjee1:39:56

       Mm

    4. RSDr. Roger Seheult1:39:56

       ... it will not give you any infrared light. However, it will help with the issue of seasonal affective disorder and circadian rhythm issues. So if you do this in the morning, this does not in any way make up for vitamin D from the sun. So if you need to supplement with vitamin D because you're not getting outside enough, you should do that. And it doesn't make up for the benefits of infrared light from the sun. So you still need to get outside during the day. But that light later in the day is not going to be beneficial in terms of depression and circadian rhythm unless it's done in the morning. And so we're trying to substitute for that with the visible light in the morning time. So that's the key for sunlight exposure. And then the other aspect is, is really after nine o'clock at night, we should be making a concerted effort to turn off lights if-- especially lights that are overhead because the receptors for this type of light are in the inferior portion of the retina, and they pick up particularly on overhead lighting. So if you wanna or you have to keep lights low, keep them, uh, low in intensity, but also low in the position of the, of the home if it's possible. And if it's really the best that you can do, turn them off completely. Don't go on screens unless you can help it. If you do have to go on screens, then make sure it's tuned away from the blue and more to a red. But again, the best thing would be no light. The second best thing would be no blue light and more of a red light filter. But there's evidence that that really is not as good as no light at all. And then, of course, the worst thing to do is just to turn all the lights on and, and keep the lights going and, and have that impact on your human body for, for long periods of time. Those are really, I think, the key interactive things that are beneficial, not just acutely, but also in the long run. And let me just, uh, let me just sort of give some evidence here for this because I think this is important. There was a study that was done at Oxford in congruence with, uh, Leiden University, where they had people draw blood throughout the year, and they measured their insulin sensitivity and their triglycerides. And what they found was is when they looked at the weather report in the previous seven days, by the hour, the more sunlight that was in their weather report in the past seven days predicted how their insulin sensitivity would be and their triglycerides. Specifically, more sunlight translated into lower triglycerides and higher insulin sensitivity.

    5. RCDr. Rangan Chatterjee1:42:31

       Wow.

    6. RSDr. Roger Seheult1:42:31

       That was literally within seven days. So if somebody's listening to this and saying, "Look, I'm gonna make a change starting today," we have actual evidence that shows that we will start to see changes within the first seven days. In fact, we have information based on Glen Jeffrey that literally within the, the first few minutes in terms of vision, we can start to see improvements after about 15 minutes of light. Now, what about long term?Do we have evidence for long term? I would challenge anyone listening to this podcast to simply go to a graph that is easily available at your public health department for your nation that would show based on the day of the year throughout the year, where do we see the maximum number of deaths from cardiovascular disease, from pneumonia, from kidney disease, from dementia, all these infectious and non-infectious diseases. And, and you will see a pattern. It's clear as day in all of the countries that are far enough away from the equator. The pattern is, is that the majority of the deaths, the peak of deaths, is one to three weeks after the shortest day of the year, so in December for those in the northern hemisphere. And the lowest, it's when the hospitals are the least impacted, when you have the least amount of people on your service in the ICU, as I can tell you, is one to three weeks after the longest day of the year. It's in July. And we see this pattern every single year. And what do I take from that? I take from that this: that sunlight impacts not only the health in terms of our vision, it impacts our cardiovascular health, it impacts our ability to fight infections, it, it, it helps with our kidneys. This is, this is why I had... I, I struggled a little bit with the very first question that you gave me is, what are the symptoms of somebody who is lacking sunlight? And when I see that all of these diseases literally in unison go up at the same time of the year after the shortest day of the year, and they all go down and then reach the lowest point one to three weeks after the longest day of the year, it tells me that sunlight impacts so much of our health that it's really difficult to pinpoint exactly where it is. So what we see here is we see short-term benefits, we see long-term benefits in terms of survival, and there are some very simple, inexpensive interventions that we can all do to make an effect. And I'll, and I'll end this little section with this. We are headed right now into the winter season. The sun is starting to pull back away from the northern hemisphere. If history is any determinant, if last year is any determinant, if all of the years that we've ever measured this is any determinant, we are gonna start to see an increase in flu, RSV, cardiac deaths. Look, we actually see more cardiac deaths, a difference in cardiac deaths during the flu season than total flu deaths, period. That's how much of an increase we see. We don't call it the cardiac season. We call it the flu season because flu goes to zero. But as we are headed into this part of the year, one of the things that we can do to reduce the incidence of a lot of these problems is to work hard, even though it's gonna be difficult to do, to get outside and to expose ourselves to sunlight. Let me just give you one study just to finish this up. Harvard Kennedy School, this is the political school of, of Harvard, did a study back in 2021, and they looked back at the flu virus and where it hit, and they were able to use CDC solar radiation data and, and also the incidence of flu, and they looked at 2009 specifically because the flu that year came a little bit early. So they were able to uncouple temperature, which is cold in December and warm in July, from sunlight, which is low in December and high in July, of course. And after they looked at all of this and did the correlative studies and did, um, the, the, uh, multi-regression analysis, they came up and they had this conclusion: sunlight is strongly protective against influenza. And when I saw that and I started to put all of these things together, it became very clear to me that one of the things that we are missing more and more of, especially since the pandemic, since we've become so accustomed to staying at home now and having things come to us and staying inside of our homes and not going outside, is that we are not getting enough sunlight, and so much disease and, and, uh, arthritis and inflammation, all of these diseases are as a result of us not getting enough sun exposure. We should double our efforts this winter to make sure that we're getting 15 to 20 minutes of sunlight. That's all I'm asking. Not sunbathing, no sun burning, just getting out into the sun to get that beneficial health that we all have had in the summer, but we're lacking in the wintertime.

    7. RCDr. Rangan Chatterjee1:47:37

       Oh, what a passionate plea for more time outside. You know, that's interesting, Roger, isn't it, about metabolic health? You mentioned insulin sensitivity and triglycerides. So improved insulin sensitivity, lower triglycerides, these are very good things for our metabolic health, and you're saying that that was heavily correlated with the amount of sunlight exposure one was receiving in the seven days prior to the blood test, right?

    8. RSDr. Roger Seheult1:48:04

       Yep.

    9. RCDr. Rangan Chatterjee1:48:04

       That has such widespread implications because if we're trying to help people with their metabolic health, which I'm often talking about on this show, you cover on your MedCram channel, right?

    10. RSDr. Roger Seheult1:48:17

        Yep.

    11. RCDr. Rangan Chatterjee1:48:18

        We're often talking about diet and exercise.

    12. RSDr. Roger Seheult1:48:20

        Yeah.

    13. RCDr. Rangan Chatterjee1:48:20

        And, and as you say, with your eight pillars of health, of course, those two things are important. At the same time, do not neglect light exposure. Getting outside will also help you with your metabolic health. And just a couple of things just to make sure we've, we've sort of hammered home. We have been saying sunlight a lot throughout this conversation, and I just wanna make sure it doesn't get misinterpreted by anyone. I think you're saying get outside, ideally sunlight, but of course, if you're living somewhere where it's cloudy for three weeks, you're still saying get outside because you will still be getting some of these benefits even if you can't see the sun.

    14. RSDr. Roger Seheult1:49:03

        Absolutely. So just to give you an idea, we measure the intensity of light, visible light, which correlates to invisible light as well, in measurements of lux. So right now in the room that I'm in, um, any room that you're in in your house can range between 50 and 100 lux. If you go outside on a bright, sunny day, it's about 100,000 lux, okay? So it's about a hu- you know, multiple times higher that you're seeing, a thousand times higher. Uh, on a cloudy day, it may be 20 to 30,000 lux, okay? So that's still magnitudes of order higher amount of sunlight than you're getting if you stay inside your home.

    15. RCDr. Rangan Chatterjee1:49:44

        Yeah. Wow. And, you know, on the subject of light in the day and darkness at night, uh, [laughs] I think my family think I'm quite militant at the moment because I'm literally, I'm so, you know, [laughs] with, when the kids are going to the bathroom in the evenings to brush their teeth, I'm like, "Get those lights off." You know, the bright LED lights, I set them really low, and then someone's like t- ramped them right up. So I'm thinking of getting them removed, but I've actually got these, um, sensor red lights in the hallway, so when you're walking around, it's just gorgeous. It's a low, warm light.

    16. RSDr. Roger Seheult1:50:17

        Yeah.

    17. RCDr. Rangan Chatterjee1:50:17

        I've got full spectrum bulbs in everyone's, uh, bedside tables. I mean, I'm very protective at home of our light environment in the evening as much as possible. It makes a massive difference. Yeah, you can see it from the evidence, but you can also feel it.

    18. RSDr. Roger Seheult1:50:34

        Yeah.

    19. RCDr. Rangan Chatterjee1:50:34

        You know, you can feel the warmth and a calm when you have that sort of lighting at home, and it, and it doesn't have to be that expensive. Um, Roger, I did wanna cover, there's a study I've heard you talk about before to do with the planting of green trees-

    20. RSDr. Roger Seheult1:50:51

        Oh, yeah

    21. RCDr. Rangan Chatterjee1:50:51

        ... and the impact it had on high sensitivity CRP. I wonder if you could finish off by outlining that study and the implications for us.

    22. RSDr. Roger Seheult1:51:00

        Yes. And to get a visual on this, I would invite anybody listening to this to go to Google and type in, um, infrared photography, and when it comes up and you see what inf- infrared photography does, notice the trees, notice the green leaves, and you will see that they are highly reflective of infrared light. Now, that's not all that they're useful for. As we talked about with, uh, air, which is part of that new start, they're, they also give off, uh, phytochemicals that can actually have an impact on our health-

    23. RCDr. Rangan Chatterjee1:51:31

        Mm

    24. RSDr. Roger Seheult1:51:31

        ... and that's kind of involved with forest bathing. But, um, for many years, we have had studies that have clearly showed that people who live in green spaces will have a reduction in diabetes, I mean, 20 to 30% reduction in diabetes, 20% reduction in all-cause mortality, 20 to 30% reduction in cardiovascular mortality. And so people have touted green spaces as something that we need to do. But the scientists who, um, sort of criticize those studies say, look, people who live in green spaces are higher socioeconomic classes. They have more money. They have better access to healthcare. This is the reason they have less of all of these, of these bad things. So I love this study because it really puts a stake through the heart of that argument. What happened in South Louisville, Kentucky, is in this four-square-mile area, they... This is an urban sprawl in South Louisville, Kentucky. It's called the Green Heart Project, if you wanna look this up. Recently, uh, published last year actually. They had this bold vision of going through the neighborhood, this four-square-mile area, um, and planting 8,000 trees. Now, now these are not little saplings that you pick up at your home improvement place. These were full, mature trees with leaves already on them. Can you imagine how that changed that environment so dramatically? And what they did was they took about 745 people before they started doing the planting, and they measured this marker called highly sensitive CRP, which is a surrogate marker that looks and is predictive of bad outcomes like heart attacks and strokes and things of that nature. Basically, it's a measure of inflammation in the body, and we know, we talked about this already, that inflammation is based somewhat on mitochondrial dysfunction, and that has linked to the diabetes and obesity and all of these things. So they measured the, uh, highly sensitive CRP levels. Okay. So it takes about two to three years, and they plant these 8,000 trees, all sorts of trees, and then they come back to the same 745 people, and they recheck their highly sensitive CRP levels after two to three years of these trees being in place. And again, they did not institute, you know, mandatory income. They did not institute an exercise program. They did not change their socioeconomic class. They didn't change any of that stuff. Same people, same environment except for the trees, living in the same place, ostensibly having the same income, and of course, they did all of the analysis and all of that. What did they find? There was a 13 on average to 20% reduction in CRP levels. Now, that's huge-

    25. RCDr. Rangan Chatterjee1:54:15

        That is huge

    26. RSDr. Roger Seheult1:54:15

        ... from a statistical standpoint. But what that actually translates into is about a 15% all-cause reduction in strokes, a reduction in, in cardiovascular disease, and this is just from planting trees, which we know are highly reflective of infrared light. What do I believe was happening? I believe obviously their, their environment looked better. Perhaps maybe even, uh, they wanted to go outside more. But here's the key I think that happens, is when you... the time that you do spend outside, when you have trees and plants in your environment, and you'll see this when you look up these images on Google, you will see so much light-And infrared light coming from these trees. These trees looks like they were designed to be infrared mirrors that are highly reflective of light in that environment. And I, I am convinced that when we live in spaces that are green and we go outside to enjoy those spaces, there are probably multiple levels of benefits that we're having. One of the ones that I'm convinced of based on all of this data and research is one of them is a bountiful plenty amount of infrared light that you don't need to be in direct sunlight. You can be in the shade, you can be sitting there amongst the trees, and you're getting the benefits of this infrared light that we've been talking about today.

    27. RCDr. Rangan Chatterjee1:55:35

        Yeah, just an incredible study, and I think just sort of closing off our conversation, the, the three key messages are immerse yourself in nature, get outside as often as you can, [laughs] and turn off the lights at night is, I guess, one way that we could try and summarize some of the practical natures of this conversation. Roger, look, this is the third time you've come on my show. I, I really enjoy talking to you. You're such a knowledgeable doctor, but also so passionate. I love the way you communicate these ideas. I love the way you dedicate yourself to making the videos on your MedCram YouTube channel, so helpful for so many people. If people wanna follow you and sort of find out more about you, where would you direct them to go?

    28. RSDr. Roger Seheult1:56:22

        Yeah. So we have a YouTube channel called MedCram, M-E-D-C-R-A-M, and that's where I post maybe about once, twice, maybe three times per month, some pretty high quality videos where we go through this data. Um, I'm probably on a daily basis active on X, and you can follow there. Uh, it's just my name, @rogerseheult. Um, but we also have a website called medcram.com, where we actually go over some of the sunlight aspects, and we have resources for medical professionals who can get continuing education credits, um, through, uh, our company and, um, and that's available as well.

    29. RCDr. Rangan Chatterjee1:56:59

        Roger, huge amount of gratitude from me to you for making time and sharing your wisdom with my audience, and I very much look forward to the next time.

    30. RSDr. Roger Seheult1:57:07

        Thank you so much.

Episode duration: 1:57:27