The science of living longer with Eric Topol | ReThinking with Adam Grant

Slowing the process of aging is something many people are interested in—and there’s a lot of pseudoscience out there about how to do it. Eric Topol is a cardiologist at Scripps and a prolific researcher on the genetics of longevity. In this episode, Eric debunks some common myths about how to live a longer life and shares his surprising findings about what actually determines a person’s lifespan and healthspan. Adam inquires about the efficacy of health supplements, and he and Eric discuss steps for preventing diseases, the role of AI in medicine, and effective practices for living a longer, healthier life. Host & Guest Adam Grant (Instagram: @adamgrant | LinkedIn: @adammgrant | Website: https://adamgrant.net/) Eric Topol (Instagram: @erictopol1 | Website: https://drerictopol.com/) Links Books: https://drerictopol.com/books/ Substack: https://erictopol.substack.com/ Join us in person at a TED conference: https://tedtalks.social/events Become a TED Member to support our mission: https://ted.com/membership Subscribe to a TED newsletter: https://ted.com/newsletters Follow TED! X: https://www.twitter.com/TEDTalks Instagram: https://www.instagram.com/ted Facebook: https://facebook.com/TED LinkedIn: https://www.linkedin.com/company/ted-conferences TikTok: https://www.tiktok.com/@tedtoks Podcasts: https://www.ted.com/podcasts The TED Audio Collective is a collection of podcasts for the curious. The TED Audio Collective videos may be used for non-commercial purposes under a Creative Commons License, Attribution–Non Commercial–No Derivatives (or the CC BY – NC – ND 4.0 International) and in accordance with our TED Talks Usage Policy (https://www.ted.com/about/our-organiz...). For more information on using TED for commercial purposes (e.g. employee learning, in a film or online course), please submit a Media Request at https://media-requests.ted.com.

Eric TopolguestAdam Granthost

Dec 12, 202538mWatch on YouTube ↗

EPISODE INFO

Released: December 12, 2025
Duration: 38m
Channel: Re:Thinking with Adam Grant
Watch on YouTube: ▶ Open ↗

EPISODE DESCRIPTION

Slowing the process of aging is something many people are interested in—and there’s a lot of pseudoscience out there about how to do it. Eric Topol is a cardiologist at Scripps and a prolific researcher on the genetics of longevity. In this episode, Eric debunks some common myths about how to live a longer life and shares his surprising findings about what actually determines a person’s lifespan and healthspan. Adam inquires about the efficacy of health supplements, and he and Eric discuss steps for preventing diseases, the role of AI in medicine, and effective practices for living a longer, healthier life. Host & Guest Adam Grant (Instagram: @adamgrant | LinkedIn: @adammgrant | Website: https://adamgrant.net/) Eric Topol (Instagram: @erictopol1 | Website: https://drerictopol.com/) Links Books: https://drerictopol.com/books/ Substack: https://erictopol.substack.com/ Join us in person at a TED conference: https://tedtalks.social/events Become a TED Member to support our mission: https://ted.com/membership Subscribe to a TED newsletter: https://ted.com/newsletters Follow TED! X: https://www.twitter.com/TEDTalks Instagram: https://www.instagram.com/ted Facebook: https://facebook.com/TED LinkedIn: https://www.linkedin.com/company/ted-conferences TikTok: https://www.tiktok.com/@tedtoks Podcasts: https://www.ted.com/podcasts The TED Audio Collective is a collection of podcasts for the curious. The TED Audio Collective videos may be used for non-commercial purposes under a Creative Commons License, Attribution–Non Commercial–No Derivatives (or the CC BY – NC – ND 4.0 International) and in accordance with our TED Talks Usage Policy (https://www.ted.com/about/our-organiz...). For more information on using TED for commercial purposes (e.g. employee learning, in a film or online course), please submit a Media Request at https://media-requests.ted.com.

SPEAKERS

Eric Topol
guest
Cardiologist and medical researcher focused on genomics, digital medicine, and longevity/healthspan science.
Adam Grant
host
Organizational psychologist and host of the podcast ReThinking with Adam Grant.

EPISODE SUMMARY

In this episode of Re:Thinking with Adam Grant, featuring Eric Topol and Adam Grant, The science of living longer with Eric Topol | ReThinking with Adam Grant explores eric Topol debunks longevity hype and outlines prevention-driven healthspan science Topol’s “wellderly” genome-sequencing study found remarkably few genetic differences between exceptionally healthy 85+ adults and typical older adults, shifting attention toward immune aging and inflammation as key drivers of healthspan.

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