How to Heal From Post-Traumatic Stress Disorder (PTSD) | Dr. Victor Carrión

How to Heal From Post-Traumatic Stress Disorder (PTSD) | Dr. Victor Carrión

Huberman LabSep 23, 20242h 26m

Andrew Huberman (host), Victor Carrión (guest)

Spectrum of stress: beneficial, chronic, and traumatic stressPTSD vs. anxiety, stress, and ADHD in childrenCue‑centered therapy and the personalized coping toolboxNeurobiology of PTSD: cortisol, HPA axis, hippocampus, prefrontal cortex, amygdalaTransgenerational and learned trauma (nature–nurture, modeling)School‑based yoga/mindfulness and sleep improvementResilience, adaptation, and organoid research on stress biology

In this episode of Huberman Lab, featuring Andrew Huberman and Victor Carrión, How to Heal From Post-Traumatic Stress Disorder (PTSD) | Dr. Victor Carrión explores healing PTSD In Kids: Cue-Based Tools To Rewire Stress Responses Andrew Huberman interviews child psychiatrist and PTSD expert Dr. Victor Carrión about the science and treatment of post‑traumatic stress, especially in children and adolescents.

Healing PTSD In Kids: Cue-Based Tools To Rewire Stress Responses

Andrew Huberman interviews child psychiatrist and PTSD expert Dr. Victor Carrión about the science and treatment of post‑traumatic stress, especially in children and adolescents.

Carrión explains stress as a spectrum—from beneficial challenge to toxic, traumatic stress—and describes how chronic or traumatic stress can dysregulate cortisol, alter brain development, and be misdiagnosed as other disorders such as ADHD.

He details “cue‑centered therapy,” which teaches children to identify triggers (cues), build a personalized coping toolbox, and use structured cognitive frameworks to create alternative responses and narratives.

The conversation also covers resilience, intergenerational trauma, school‑based yoga and mindfulness that improved children’s sleep and reduced amygdala activity, and cutting‑edge organoid research aimed at uncovering the biology of resilience.

Key Takeaways

Stress is a spectrum and some stress is essential for development.

Carrión frames stress as an inverted U‑shaped curve: modest stress improves performance, learning, coping skills, and problem‑solving, while too little stress leads to disengagement and too much leads to allostatic load (physiological cost to the body). ...

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PTSD in children is often cumulative and easily missed or misdiagnosed.

PTSD symptoms in kids commonly arise from an accumulation of stressors (violence, poverty, instability) rather than a single event. ...

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Avoidance fuels PTSD, but unstructured rumination is also harmful.

Carrión’s team uses the phrase “PTSD feeds on avoidance”: denying events, avoiding treatment, or pretending symptoms will disappear allows the condition to worsen and invites complications like substance use or self‑harm. ...

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Evening cortisol dysregulation in traumatized kids disrupts sleep and development.

Children with PTSD symptoms retain a normal circadian cortisol rhythm overall, but their pre‑bedtime cortisol remains abnormally high. ...

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Cue‑centered therapy teaches children to map triggers and build a personalized coping toolbox.

Cue‑centered therapy targets neutral sensory cues (colors, weather, sounds, timbres of voices) that became linked to trauma via classical conditioning. ...

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A simple ‘four‑corner square’ model helps break automatic reactions and create space.

Carrión uses a square with four corners—thoughts (cognitions), emotions, physical sensations (somatic), and actions—to deconstruct problematic responses (e. ...

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School‑based yoga and mindfulness can meaningfully improve sleep and brain function.

In East Palo Alto schools, a yoga‑mindfulness curriculum delivered 2–3 times weekly (15–50 minutes) led to behavior improvements so pronounced that principals noticed discipline referrals dropped. ...

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Notable Quotes

PTSD feeds on avoidance.

Dr. Victor Carrión

Children are really not [inherently] resilient; they’re more vulnerable. They have the opportunity to become resilient if we help them.

Dr. Victor Carrión

What if it’s not the presence of that adult, but there’s something in that child that makes them seek and maintain that type of relationship?

Dr. Victor Carrión

The best psychiatrists that I know actually say very little. They listen.

Dr. Victor Carrión

Stress operates in our lives as an inverted U‑shaped curve. We don’t want to get rid of stress; we just want to return to that optimal point.

Dr. Victor Carrión

Questions Answered in This Episode

In practical terms, how would a parent or teacher distinguish between a child’s hyperactivity from true ADHD versus cue‑triggered hypervigilance from trauma, especially when both might be present?

Andrew Huberman interviews child psychiatrist and PTSD expert Dr. ...

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For a teenager who recognizes that certain subtle cues (like specific tones of voice or social media content) trigger panic or dissociation, how exactly would you recommend they start mapping and working with those cues using the square model and the toolbox?

Carrión explains stress as a spectrum—from beneficial challenge to toxic, traumatic stress—and describes how chronic or traumatic stress can dysregulate cortisol, alter brain development, and be misdiagnosed as other disorders such as ADHD.

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Your organoid studies found stress‑induced changes in collagen‑related genes linked to accelerated aging—do you envision any realistic interventions (behavioral or pharmacologic) that could specifically target this ‘accelerated aging’ pathway in traumatized youth?

He details “cue‑centered therapy,” which teaches children to identify triggers (cues), build a personalized coping toolbox, and use structured cognitive frameworks to create alternative responses and narratives.

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In the Puerto Rico project, if a child benefits significantly from classroom yoga/mindfulness but still screens high for PTSS, how do you decide the intensity and format of cue‑centered therapy they receive, and are there markers that help you triage limited counseling resources?

The conversation also covers resilience, intergenerational trauma, school‑based yoga and mindfulness that improved children’s sleep and reduced amygdala activity, and cutting‑edge organoid research aimed at uncovering the biology of resilience.

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Some critics argue that widespread use of school‑based yoga and mindfulness risks ‘medicalizing’ normal stress or pushing a one‑size‑fits‑all solution—how do you respond to that concern, and what safeguards or flexibilities do you build in to respect cultural, religious, and individual differences?

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Transcript Preview

Andrew Huberman

(peaceful music) Welcome to the Huberman Lab Podcast, where we discuss science and science-based tools for everyday life. I'm Andrew Huberman, and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine. My guest today is Dr. Victor Carrion. Dr. Victor Carrion is a professor and the vice chair of psychiatry and behavioral sciences at Stanford University School of Medicine. He is one of the world's foremost experts on post-traumatic stress disorder, in particular, the treatment of post-traumatic stress disorder in children and adolescents, although his knowledge and today's discussion certainly extends to adult PTSD as well. Dr. Carrion is also the director of the Stanford Early Life Stress and Resilience Program, and today's discussion focuses on the psychological and the neurobiological underpinnings of PTSD and which treatments are most effective for PTSD. We focus heavily on a particular therapy called cue-centered therapy that was developed by Dr. Carrion and colleagues that has been shown to offset the triggering by words or events or memories that often are the precursors to PTSD episodes, and this has been shown to be effective in both children and adults. Today's discussion explores the difference between anxiety, stress, and trauma. We talk about how those things, of course, are related, but how they can be separated out to better understand if indeed somebody has trauma and how to best approach the treatment of that trauma. As you'll soon see, what makes Dr. Carrion's work so unique is that it combines the psychological, the neurobiological, but also practical tools such as mindfulness. It relates mindfulness and cognitive behavioral therapy to the underlying biology and what's known about the psychiatry and psychology of PTSD at its different stages depending on the trauma, the age of the person, et cetera. Today, Dr. Carrion clearly explains all of that so that by the end of today's conversation, you'll really understand what PTSD is and is not and of course the best ways to treat it. Before we begin, I'd like to emphasize that this podcast is separate from my teaching and research roles at Stanford. It is, however, part of my desire and effort to bring zero-cost-to-consumer information about science and science-related tools to the general public. In keeping with that theme, I'd like to thank the sponsors of today's podcast. Our first sponsor is Eight Sleep. Eight Sleep makes smart mattress covers with cooling, heating, and sleep-tracking capacity. Now, I've spoken many times before on this podcast about the critical need for us to get adequate amounts of quality sleep each night. That's truly the foundation of all mental health, physical health, and performance, and one of the best ways to ensure that you get a great night's sleep is to control the temperature of your sleeping environment, and that's because in order to fall and stay deeply asleep, your body temperature actually has to drop by about one to three degrees, and in order to wake up feeling refreshed and energized, your body temperature actually has to increase about one to three degrees. Eight Sleep makes it incredibly easy to control the temperature of your sleeping environment by allowing you to control the temperature of your mattress cover at the beginning, middle, and end of the night, and it turns out the ability to do so allows you to get the maximum amount of deep sleep, slow-wave sleep, and rapid eye movement sleep at the different stages of the night. I've been sleeping on an Eight Sleep mattress cover for nearly four years now, and it has completely transformed and improved the quality of my sleep. Eight Sleep has now launched their newest generation of the Pod Cover, the Pod 4 Ultra. The Pod 4 Ultra has improved cooling and heating capacity, higher fidelity sleep tracking technology, and even has snoring. If you'd like to try an Eight Sleep mattress cover, go to eightsleep.com/huberman to save up to $350 off their Pod 4 Ultra. Eight Sleep currently ships in the USA, Canada, UK, select countries in the EU, and Australia. Again, that's eightsleep.com/huberman. Today's episode is also brought to us by BetterHelp. BetterHelp offers professional therapy with a licensed therapist carried out entirely online. I've been doing weekly therapy for well over 30 years. Initially, I didn't have a choice, it was a condition of being allowed to stay in school, but pretty soon I realized that doing regular quality therapy is an extremely important component to overall health. In fact, I consider doing regular therapy just as important as getting regular physical exercise, including cardiovascular exercise and resistance training, which of course I also do every single week. There are essentially three components to excellent therapy. First of all, excellent therapy should provide good rapport with somebody who you can trust and talk to about all issues in your life. Second of all, it should provide support in the form of emotional support or directed guidance or both. And thirdly, expert therapy should provide useful insights, insights that can allow you to do better not just in your emotional life and relationship life, but of course also your relationship to yourself, your professional life, and all of your career and life goals. With BetterHelp, they make it very easy to find an expert therapist with whom you can build all three of these effective components of therapy. If you'd like to try BetterHelp, you can go to betterhelp.com/huberman to get 10% off your first month. Again, that's betterhelp.com/huberman. Today's episode is also brought to us by Waking Up. Waking Up is a meditation app that offers hundreds of guided meditation programs, mindfulness trainings, yoga nidra sessions, and more. I started practicing meditation when I was about 15 years old, and it made a profound impact on my life. And by now, there are thousands of quality peer-reviewed studies that emphasize how useful mindfulness meditation can be for improving our focus, managing stress and anxiety, improving our mood, and much more. In recent years, I started using the Waking Up app for my meditations because I find it to be a terrific resource for allowing me to really be consistent with my meditation practice. Many people start a meditation practice and experience some benefits, but many people also have challenges keeping up with that practice. What I and so many other people love about the Waking Up app is that it has a lot of different meditations to choose from, and those meditations are of different durations, so it makes it very easy to keep up with your meditation practice both from the perspective of novelty, you never get tired of those meditations, there's always something new to explore and to learn about yourself and about the effectiveness of meditation, and you can always fit meditation into your schedule even if you only have two or three minutes per day in which to meditate. If you'd like to try the Waking Up app, please go to wakingup.com/huberman where you can access a free 30-day trial. Again, that's wakingup.com/huberman to access a free 30-day trial. And now for my discussion with Dr. Victor Carrion.Dr. Victor Carrion, welcome.

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