
The Science of Love, Desire & Attachment | Huberman Lab Essentials
Andrew Huberman (host)
In this episode of Huberman Lab, featuring Andrew Huberman, The Science of Love, Desire & Attachment | Huberman Lab Essentials explores how attachment, autonomic arousal, and neurochemistry shape romantic bonds deeply Huberman outlines the four classic attachment styles from Mary Ainsworth’s “Strange Situation” research and explains how these early templates often predict adult romantic attachment patterns, while emphasizing they can change with awareness.
How attachment, autonomic arousal, and neurochemistry shape romantic bonds deeply
Huberman outlines the four classic attachment styles from Mary Ainsworth’s “Strange Situation” research and explains how these early templates often predict adult romantic attachment patterns, while emphasizing they can change with awareness.
He frames bonding as an interaction among three major systems: autonomic nervous system regulation (the “seesaw”), neural circuits for empathy/autonomic matching (notably insula and prefrontal cortex), and “positive delusions” that stabilize relationships.
He highlights relationship failure predictors from Gottman research—criticism, defensiveness, stonewalling, and especially contempt—and connects them to breakdowns in empathy and autonomic coordination.
Finally, he discusses libido biology (testosterone, estrogen, dopamine, autonomic balance) and reviews evidence for supplements (maca, tongkat ali, tribulus) with cautions about medical oversight and individual variability.
Key Takeaways
Attachment style is an early-formed template that often persists into romance.
Secure, avoidant, ambivalent/resistant, and disorganized patterns observed in toddlers tend to predict later romantic attachment behaviors, suggesting continuity from caregiver bonding circuits to adult partnership dynamics.
Get the full analysis with uListen AI
Awareness can shift attachment patterns over time.
Huberman emphasizes that attachment “templates” are malleable, and simply knowing your tendencies—and watching them in real time—can be a powerful lever for change.
Get the full analysis with uListen AI
Healthy relationships rely on co-regulation plus self-regulation.
A strong bond often means another person’s presence improves your autonomic state, but long-term stability also requires the ability to self-soothe when they’re absent (healthy interdependence vs. ...
Get the full analysis with uListen AI
Autonomic “matching” is a biological core of empathy and bonding.
Empathy is framed as one person’s autonomic state influencing the other’s; the insula helps track internal sensations while also monitoring the other person, and the prefrontal cortex helps decide whether/how to match.
Get the full analysis with uListen AI
“Positive delusions” help stabilize love over time.
Bond durability is supported by selectively positive beliefs (e. ...
Get the full analysis with uListen AI
Contempt is the most corrosive relationship behavior.
Among Gottman’s Four Horsemen—criticism, defensiveness, stonewalling, contempt—contempt is presented as the strongest predictor of breakup/divorce because it opposes empathy, positive regard, and autonomic coordination.
Get the full analysis with uListen AI
Libido depends on balance: hormones, dopamine, and autonomic state.
Testosterone and estrogen both support libido in males and females; dopamine supports pursuit/motivation, but too much arousal can impair the parasympathetic activation needed for physical sexual arousal—so “more dopamine” is not always better.
Get the full analysis with uListen AI
Some supplements show evidence for libido, but effects and mechanisms differ.
Maca (2–3g/day) may increase desire without changing hormones; tongkat ali may increase free testosterone and libido in some; tribulus shows mixed libido results but may raise free/bioavailable testosterone in certain populations—medical guidance and monitoring are advised.
Get the full analysis with uListen AI
Notable Quotes
“The good news is that these templates can shift over time, and one of the more powerful ways to shift those templates over time is purely by the knowledge that they exist and the understanding that those templates are malleable.”
— Andrew Huberman
“The way to think about the autonomic nervous system is it's kind of a seesaw.”
— Andrew Huberman
“Dopamine is… mainly a molecule of motivation, craving, and pursuit.”
— Andrew Huberman
“They've identified what are called the Four Horsemen of Relationships… with contempt being the most powerful predictor of breaking up.”
— Andrew Huberman
“Contempt has actually been referred to as the sulfuric acid of relationship.”
— Andrew Huberman
Questions Answered in This Episode
In practical terms, how can someone accurately identify whether they’re secure, avoidant, ambivalent/resistant, or disorganized in adult relationships (beyond “gut feeling”)?
Huberman outlines the four classic attachment styles from Mary Ainsworth’s “Strange Situation” research and explains how these early templates often predict adult romantic attachment patterns, while emphasizing they can change with awareness.
Get the full analysis with uListen AI
When you say “autonomic coordination” is a hallmark of love, what observable signs (breathing, heart rate, agitation/soothing patterns) should someone look for in themselves during conflict and repair?
He frames bonding as an interaction among three major systems: autonomic nervous system regulation (the “seesaw”), neural circuits for empathy/autonomic matching (notably insula and prefrontal cortex), and “positive delusions” that stabilize relationships.
Get the full analysis with uListen AI
How do “positive delusions” differ from unhealthy denial or rationalizing clear incompatibilities—where’s the line?
He highlights relationship failure predictors from Gottman research—criticism, defensiveness, stonewalling, and especially contempt—and connects them to breakdowns in empathy and autonomic coordination.
Get the full analysis with uListen AI
For each of Gottman’s Four Horsemen, what is the closest “replacement behavior” that preserves honesty but avoids triggering defensiveness and contempt?
Finally, he discusses libido biology (testosterone, estrogen, dopamine, autonomic balance) and reviews evidence for supplements (maca, tongkat ali, tribulus) with cautions about medical oversight and individual variability.
Get the full analysis with uListen AI
The WWII bombing example suggests caregiver state imprints on children—what modern equivalents (e.g., chronic phone stress, financial stress) might create similar autonomic shaping in families?
Get the full analysis with uListen AI
Transcript Preview
Welcome to Huberman Lab Essentials, where we revisit past episodes for the most potent and actionable science-based tools for mental health, physical health, and performance. [music] I'm Andrew Huberman, and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine. Today, we are going to talk about the psychology and the biology of desire, love, and attachment. One of the most robust findings in the field of psychology is this notion of attachment styles, and this was something that was discovered through a beautiful set of studies that were done by Mary Ainsworth in the 1980s, in which she developed a laboratory condition called the strange situation task. The strange situation task involves a parent, typically a mother, in the studies that were done, but a parent or other caregiver bringing their child, their actual child, into a laboratory, and there's a room with a stranger, and the mother enters the room with the child, and there's some toys in the room, and typically, the mother and the stranger will talk. Obviously, the stranger is part of the experiment, [chuckles] it's not just some random person off the street, and the child is allowed to move about the room. They can play with toys or not. But then at some point, the mother leaves, and then at some point later, designated by the experimenter, the mother comes back. And what is measured in these studies is both how the child, the toddler, reacts to the mother leaving and how the child reacts to the mother returning at the end of the experiment. So there are a lot of variations of this, but the basic findings are that toddlers, children, fall into four different categories of attachment style. The first style is the so-called secure attachment style. The secure attachment style is one in which the child will engage with the stranger, with the experimenter, while the parent is present in the room, but that when the parent or other caregiver leaves, the child does get visibly upset. However, when the caregiver, meaning the mother or father or other caregiver, returns, the child visibly expresses happiness that the caregiver has returned. And the interpretation of this is that the secure child feels confident that the caregiver is available and will be responsive to their needs and their communications. These children are also very good at exploring novel environments after the parent is gone and while the parent is there. The second category is the so-called anxious, avoidant, or insecurely attached. They do not exhibit distress on separation, and they generally tend to have, um, some tendency to approach the, the r- the caregiver when they return, but there doesn't seem to be a, a general expression of joy. The third category is the so-called anxious, ambivalent/resistant, insecure category. The anxious, ambivalent, resistant, insecure toddlers really show distress even before separation from their mother or other caregiver, and they tend to be very clingy and difficult to comfort when the caregiver returns. And the third category of attachment style is the so-called disorganized or disoriented, or D, for the letter D, uh, babies. It seems like these children just don't really know how to react to a separation, and they just, uh, start to manifest behaviors and emotional tones that aren't observed in other situations. Now, what's interesting about this from the perspective of desire, love, and attachment, is that the categorizations of children into one of these four different categories as toddlers is strongly predictive of their attachment style in romantic partnerships later in life, which is, to me, both amazing and surprising and not surprising all at the same time. The good news is that these templates can shift over time, and one of the more powerful ways to shift those templates over time is purely by the knowledge that they exist and the understanding that those templates are malleable. So I mentioned that the neural circuits for child-parent or child-caregiver attachment are repurposed for romantic attachment later in life. But what are these neural circuits? What do they do? I mean, uh, it's so, uh, attractive, if you will, to think about a brain area that controls love or a brain area that controls desire or a brain [chuckles] area that controls attachment, but it simply doesn't work that way. Instead, there are multiple brain areas that, through their coordinated action, create a sort of a song that we call desire or a song that we call love, or a song that we call attachment, not a, a literal song, but rather different brain areas being active in different sequences and with different intensities can make us feel as if we are in the mode that we call desire or in the mode of love or in the mode of attachment. But beneath all of that is this element of autonomic arousal. So the way to think about the autonomic nervous system is it's kind of a seesaw. We can be alert and calm, or we can be very, very alert. We can be in a state of panic. We can be fast asleep, so we can be extremely calm, or we can just be kind of sleepy, um, semi-calm, um, and but still also alert. So th- think about it like a seesaw, and that seesaw has a, a hinge, and that hinge defines how tight or loose that seesaw is, how readily it can tilt back and forth. Our autonomic tone is how tight that hinge is, and there are biological mechanisms to explain this, but here, I just want to stay with the analogy of the seesaw for now. The interactions between child and caregiver early in life take-... the child and the caregiver from one end of the seesaw to the other, from being very alert in a state of play, for instance, to being nursed and being very soothed until we go to sleep. And of course, we each have a seesaw, the parent and the child has a seesaw, and they're interacting. What do I mean by that? Well, there are beautiful studies, and beautiful not in the sense that they focused on a pleasant topic, but beautiful because they were done so beautifully well, that looked at, for instance, the response of mothers and their physiologies, and the response of children and their physiologies during the bombing of cities during World War II. So an unpleasant situation, but what was revealed during the course of these studies was that if the mothers were very stressed during an onslaught of bombing of the city, the children's physiologies tended to be stressed also and persisted in being stressed long after that stressful episode was done. They actually followed these children well out for many decades afterwards. Conversely, if the parent, and, and in this case, again, it was mothers that, that were explored in these studies, had turned this whole business of going into the bomb shelters into somewhat of a game, all right? Taking it seriously, but essentially telling the children, "Okay, it's time to go," but not expressing much stress or distress, the children also didn't develop much stress or distress or trauma. Now, there were exceptions to this, of course, but in general, that was the rule, that the autonomic nervous systems of children tend to mimic the autonomic nervous systems of the primary caregiver. So if I were to offer a set of tools around these topics of desire, love, and attachment, I would say, first of all, you might want to think about whether or not you fall into the secure, insecure, or other, um, attachment styles. Second, I think it is vitally important for all of us, but certainly for people that are in relationships or seeking relationships, to be able to at least have some recognition of where our ner- autonomic nervous system tends to reside, both in terms of when we are with somebody and when they leave. When we are apart for long periods of time, can we calm ourselves? Can we self-soothe, or are we very much dependent on the presence of another in order to feel soothed? Now, I absolutely want to emphasize that there is nothing wrong, in fact, there's everything right, with feeling great in the presence of somebody else. That is actually a, a hallmark of, of strong and quality attachments. A key element of healthy interdependence is that, yes, our autonomic nervous system is adjusted by the presence of another, but that also that we can adjust our own autonomic nervous system even in the absence of that person. So if the autonomic nervous system is one key component of desire, love, and attachment, what are the other two? Not surprisingly, the dopamine system in the brain is associated with desire, love, and attachment, and mainly with desire, although to some extent, love. Dopamine is a neurochemical sometimes associated with reward, but as some of you have heard me say, uh, before, it is mainly a molecule of motivation, craving, and pursuit. And that motivation, craving, and pursuit that relates to dopamine is not unique to attachment or love or sex or mating, et cetera. It is a universal generic currency in the brain for pursuing something. I want to just discuss the two neural circuits that use dopamine, that use serotonin and oxytocin, and that collaborate with the autonomic nervous system to drive what we call desire, love, and attachment. And the three circuits are autonomic nervous system, we talked about that one. Then there's the nervous system components or the neural circuits for empathy, for being able to see and respond to and indeed match the emotional tone or the autonomic tone of another. And then there's the third category, and this might surprise some of you, it certainly surprised me, but the data point to the fact that the third neural circuit that's very important for establishing bonds is one associated with positive delusions. So given that the neural circuits for empathy are absolutely crucial for falling in love and maintaining stable attachments, I'd like to talk about those neural circuits and what they are. Now, often when we hear empathy, we think, oh, empathy is really about listening to and really understanding what somebody else is feeling, maybe even feeling what they're feeling. And indeed, that's the case, but what do we mean by that, right? What is it to feel what another feels? Well, what it means is that their seesaw is driving your seesaw, or your seesaw is somehow driving their seesaw. That's a form of empathic matching, and there are indeed neural circuits for that. The neural circuits for empathy, again, there are many, but mainly two structures that you should know about. The prefrontal cortex, which is how we perceive things outside of us and make decisions on the basis of those perceptions, how we organize those decisions. And an area of the brain called the insula, I-N-S-U-L-A. The insula is a really interesting brain area that allows us to interocept, to pay attention to what's going on inside our body and to split some of our attention to exterocept. And the insula is essentially splitting one's attention between how we feel i- ourselves, how our body feels, what we're thinking, with the thinking and the body's, bodily sensations of the other. Okay, so we have the autonomic nervous system, and then we have this thing that we're calling empathy, which is really about autonomic matching. And again, the insula and the prefrontal cortex are neural circuits that are crucial for autonomic matching because they allow us to say, "What's out there, and do I want to match to it or not?" Okay? And then the third category is the neural circuit associated with [chuckles] self-delusion. What do we mean by positive delusion? Positive delusion is belief that-... only this person can make me feel this way. Now, positive delusion is critical. If you look at the stability of relationships over time, what you find is that there are some key features of interactions between individuals that predict that a relationship will last, and those are many, but mainly fall under this category of positive delusions. I'll return to those and what those exactly look like, but there are also just a handful of things that predict that a, a relationship will fail over time. This is largely the work of the Gottmans. It's actually a husband and wife team up at the University of Washington in Seattle, and they've identified what are called the Four Horsemen of Relationships. Those four behaviors, what they call the Four Horsemen of the Apocalypse, [chuckles] uh, for relationships, are one, criticism, two, defensiveness, three, stonewalling, and four, contempt, with contempt being, um, the most powerful predictor of, uh, breaking up. Um, criticism, of course, does not mean that there's, uh, no place for criticism in stable relationships. Of course, there is. Uh, it has to do with how frequent and how intensely that criticism is voiced. Defensiveness, of course, is defensiveness, uh, we know as the sort of lack of ability to hear another or to adopt their stance, so lack of empathy, I think is, is a, um, one way to interpret defensiveness. Stonewalling, which is actually another form of lack of empathy. It's a turning off of this neural circuit that's so critical for desire, love, and attachment. The stonewalling essentially means, uh, the emotional response or the request of another is completely cut off, and then contempt, and contempt has actually been referred to as the sulfuric acid of relationship. Uh, I didn't say that, but Gottman and colleagues have, that it is, uh, such a powerful predictor of divorce and breakups, uh, in the future. Contempt, of course, uh, by definition, is the feeling that a person or thing is beneath consideration, worthlessness, or deserving scorn. That runs counter to all of the neural circuits, all three of the neural circuits that we talked about before. It certainly is, um, it is the antithesis of empathy. It is anything but a positive delusion. It's really looking at the other individual, either accurately or inaccurately, as somebody that you kind of despise, and then it is an absolute inversion of the autonomic seesaw matching that I was talking about before. It's a dissociating of your seesaw from their seesaw. They're very excited about something, you're unexcited by it, and therefore, it's not, um, surprising that it is so strongly predictive of breakups, and in the case of married couples, of divorce. I want to now talk about an article that came out a little over ten years ago that talked about the universality of love and the ability to fall in love. An article was published in The New York Times in twenty fifteen that related to some psychological studies that were done, as well as some clinical work, as well as some, uh, what I would call, um, pop psychology or things that fall outside the, the domains of academic science. And the, the whole basis of this article was, um, thirty-six questions that lead to love, and it involved a listing out, indeed, of thirty-six questions, a set divided into set one, set two, and set three, that progress from somewhat ordinary questions about life experience, um, and self-report, to more let's call them deep questions about people's, uh, values and, and things that are emotionally close to them. And I'll just give an example of a few of these. Some of the questions in set number one were, um, for instance, what would constitute a perfect day for you? For what in your life do you feel most grateful? Kind of standard questionnaire stuff. In set two, um, what is your most treasured memory? Uh, what is your most terrible memory? So these are, are, as you can tell, are drilling a little bit deeper into one's, um, personal experience and, and emotional system. And then set three, questions twenty-five, uh, through thirty-six, um, are things, um, you know, uh, what is a, a very embarrassing moment in your life? Uh, when did you last cry in front of another person, uh, and by yourself? What is something that's too serious to be joked about? So it's going, um, deeper into, uh, one's emotional system. Now, the reason this article got so much traction, and the reason I'm bringing it up today, is that there was a statement that was made in and around this article, that if two people went on a date or simply sat down and asked each other these questions, that by the end of that exchange, where one person asks thirty-six questions and the other person answers all thirty-six, and then the other person asks all thirty-six, and the other person answers all thirty-six, that they would fall in love, right? Which seems like kind of a ridiculous thing. Uh, and yet, it is the case that people who go through this exercise report feeling as if they know the other person quite well and feeling certain, uh, levels of attachment or even love and desire for the other person that they would not have predicted, uh, had they not gone through that process. So what's going on in this exchange of questions and answers of a progressively more emotional and deep level? We know, based on recent studies, and I've covered this before o- on this podcast, but I'll mention again, that when individuals listen to the same narrative, their heart rates tend to synchronize or at least follow a very similar pattern, even if they're not in the same room listening to a given narrative. So I'm not all that surprised that people find that they fall in love-... in quotes, um, after answering these questions to one another, because essentially, the way these questions are laid out is they establish a narrative. They establish a very personal narrative, and the other person is listening very closely. So I don't want to seem overly reductionist. I'll never propose that all of our sensation, perception, action, and experience in life boils down to, uh, us just being bags of chemicals and the action of those chemicals or any aspect of our nervous system. And yet, in looking across the psychological literature of development of attachment, in the psychological literature of adult and romantic attachment, and what makes and breaks those attachments, it's very clear to me, and I think courses through the literature at multiple levels, that autonomic coordination is a hallmark feature of desire, a hallmark feature of what we call love, and a hallmark feature of what we call attachment. You hear a lot out there that, you know, in order to form a really strong relationship, uh, you have to have a good relationship with yourself, or you have to love yourself, or, uh, you often hear, for instance, that, you know, it's exactly when you're not looking for a relationship that you're gonna find one. You hear this stuff, right? But none of that is really grounded in any studies. There's a particular study that I found, uh, this was published in Frontiers in Psychology, but it's a experimental study that involves, um, neuroimaging. The title of this study is Manipulation of Self-Expansion Alters Responses to Attractive Alternative Partners, and I love the design of this study. What they did in this study is they took couples, and they evaluated members of that relationship for what's called self-expansion. Now, self-expansion is a metric that involves one's perception of self as seen through the relationship to the other. In other words, that one of the reasons why many people enter relationships is that it makes us feel good about ourselves and more capable, and I would see that as a healthy interdependence, not necessarily codependence. In any event, this study looked at whether or not people have high levels of self-expansion through the actions or statements of their significant other and how that influences their perception of people outside the relationship, meaning how attractive they perceive people outside the relationship to be, turns out to be strongly influenced by, A, whether or not their self-expansion is very strongly driven by the other person that they are involved with, that they're in the romantic relationship with, and whether or not that's being expressed to them. So here's how the study went. First of all, they rated or categorized individuals on the basis of the self-expansion metric. Some people have more of a potential to experience self-expansion through others, right? Some of us feel great about ourselves, and we're kind of topped off at the... Others don't feel so great about themselves, but they can feel much better in response to praise, in particular, praise or self-expansion type, um, behaviors or statements from people that we really care about, and still other people are a mixture of the two, they kind of moderate levels of both. So they rated them on this scale, and then they had people experience self-expansion narratives. They heard their significant other say really terrific things about them and about the relationship, in particular, that the relationship, uh, that they have was exciting, novel, and challenging, so that was one form of self-expansion, and they went into some detail as to why that was the case in their particular relationship. Or they heard a narrative from a s-- from their significant other about strong feelings of love between the two that had been experienced previously in the relationship. So in the one case, it sort of directed more towards them, and in the other case, it's more about the relationship itself. And then they did brain imaging of one person in the relationship while that person assessed the attractiveness of people outside the relationship. And what they found was that people who were primed for this self-expansion had lower activation of brain areas associated with assessing others' attractiveness than did the people who experienced a lot of self-expansion. Now, the takeaway from that, at least the way I read this study, is if you're with somebody who really benefits from or experiences a lot of self-expansion, unless you really want them to pay attention to the attractiveness of other people, it stands to reason that they would benefit from more self-expansion type gestures or statements, okay? Not so much centered on the relationship. We have such a great relationship. There's so much love. It's so great. That, too, but in the context of this study and these findings, that the person is really terrific, that the relationship that they've created together is really exciting, novel, and challenging, that there's a narrative around the relationship that really has a lot to do with the dynamics between the individuals, in particular, that the person who really likes self-expansion is vital to that dynamic, okay? So it's not looking down at the relationship as a set of equals. There is sort of this bias written into this, of that this person is really essential for the relationship. I'm not saying this is something that anyone has to do. I'm not saying this is right or wrong. This is just what the data say. But what's remarkable is that in the absence of those statements, people who have or that rate high on this scale of self-expansion, rate attractive alternative partners as more attractive. Now, that's interesting to me because it means that their actual perception of others is changing. They're still seeing all these attractive people. It's just that if they're feeling filled up, uh, in air quotes, uh, psychologically filled up, emotionally filled up, autonomically filled, uh, enhanced, uh, in the, in the language that we're using today by this self-expansion narrative, well, then the same set of attractive faces appear less attractive to a given individual.... Now, whether or not this predicts cheating or loyalty, [chuckles] uh, I certainly can't say. Uh, that would be very hard to assess in a, in neuroimaging. But I find this study, again, the title, "Manipulation of self-expansion alters responses to attractive alternative partners," to be absolutely fascinating, because, again, it points to the fact that the interactions with our significant others shapes our autonomic arousal, shapes our perception of self, and thereby shapes our perception of other potential partners in the outside world, or shuts us down to the potential of other people in the outside world. And so this really does point to the idea that while it is important to link our autonomic nervous systems to establish desire, love, and attachment, that we wanna have a stable internal representation of ourselves, a stable autonomic nervous system to some degree or another, so that we can be in stable romantic partnership with another individual if that's what we're really trying to do. In the Huberman Lab podcast, I discuss both science and science-based tools, and so I'd be remiss if I didn't actually cover some of the tools that relate to those deeper biological mechanisms. Now, the hormones testosterone and estrogen are almost always the first biological chemicals and hormones that are mentioned and described and explored when thinking about desire, and love and attachment, too, for that matter, since love and attachment stem from desire. The simple stereotyped version of the hormones testosterone and estrogen are that testosterone drives libido or increases it, AKA sex drive, and that estrogen somehow blunts it or is not involved in libido and sex drive, and that is simply not the case. Yes, testosterone and some of its other forms, like dihydrotestosterone, are strongly related to libido and sex drive and the pursuit and ability to mate. However, the hormone estrogen is also strongly associated with libido and mating behavior. So much so that for people that either chemically or for some other reason have very low estrogen, libido can severely suffer. So it's a coordinated dance of estrogen and testosterone in both males and females that leads to libido or sex drive. With that said, there are things that can shift libido in both men and women in the direction of more desire or more desire to mate, either to seek mates or to mate with existing partners. Now, a common misconception is that because dopamine is involved in motivation and drive, that simply increasing dopamine through any number of different mechanisms or tools will increase libido and sex drive, and that's simply not the case either. It is true that some level of dopamine or increase in dopamine is required for increases in libido. However, because of dopamine's relationship to the autonomic nervous system, and because the autonomic nervous system is so intimately involved, no pun intended, in sexual activity, in seeking and actual mating behavior, as I described earlier, it's actually the case that if people drive their dopamine system too high, they will be in states of arousal that are high enough such that they seek and want sexual activity, but they can't actually engage the parasympathetic arm of the autonomic nervous system sufficient to become physically aroused. So this is a, an important point to make because I think that a lot of people are under the impression that if they just drive up testosterone, increase dopamine, and generally get themselves into high states of autonomic arousal, that that's gonna increase their libido. But that's simply not the way the system works. It's that seesaw and that seesawing back and forth that is the arc of arousal that we talked about earlier. Now, there are substances, legal, over-the-counter substances, uh, that fall under the categorization of supplements, that do indeed increase libido and arousal. I wanna be clear, however, that these are by no means required. Uh, many people have healthy libidos or, or have libidos that are healthy for, uh, their life and, and what they need and, and want. Um, and as always, in any discussion about supplementation, you absolutely have to check with your physician. I don't just say that to protect us, I say that to protect you. Your health and wellbeing is dependent on you doing certain things and not doing others, and everybody is different. Nonetheless, there are studies that point to specific substances that are sold over the counter, that at least in the United States, are legal, and that have been shown s- to be statistically significant in increasing measures of libido. There are many such substances, but three that in particular have good peer-reviewed research to support them are maca, M-A-C-A, which is actually a root; tongkat ali, also sometimes called longjack, I didn't name them, forgive me; and tribulus or tribulus, it's sometimes called. I'm gonna talk about each of these in sequence. But on the whole, the studies on maca are quite convincing, that consumption of two to three grams per day of maca, which generally is sold as a powder or a capsule, typically consumed early in the day because it can be somewhat of a stimulant, meaning it can increase alertness, and you wouldn't want it to interfere, uh, with sleep by taking it too late in the day. But in studies that include both men and women of durations anywhere from eight to 12 weeks, of athletes and non-athletes, and in-... different variations of maca. Turns out there's black maca, red maca, yellow maca. There are a bunch of different forms of maca, but that they can increase subjective reports of sexual desire independent of hormone systems, meaning it does not seem, at least based on the existing literature, that maca increases testosterone or changes estrogen, at least not on the timescales that these studies were done or with the measures that were, uh, performed in these studies. Another substance that has been shown to increase libido across a range of human populations is so-called Tongkat ali. This is an herb. There's a Malaysian version and an Indonesian version. Um, my understanding is that the Indonesian variety of Tongkat ali is the one that is most potent for, uh, its effects on libido. Previously, I've talked about Tongkat ali taken in four hundred milligram per day capsules as a means to increase the amount of free, meaning unbound testosterone. So testosterone has a both bound form and an unbound form. Very briefly, the bound form is bound to albumin in the blood or to so-called sex hormone binding globulin. Uh, when it's bound, it can't be biologically active at many cells. Uh, it is important that some of it be bound in order to get a sort of time release and, and proper distribution of testosterone through the body, but it is the unbound free testosterone that can really have its most potent effects. And there's some evidence that Tongkat ali can increase the amount of unbound, so-called free testosterone by lowering sex hormone binding globulin, although it is almost certain that it has other routes of mechanism as well. Nonetheless, there are some reports of Tongkat ali increasing libido. The question always comes up around discussion of supplements. Do you need to cycle these things? The only way to determine that is really to do your blood work, monitor liver enzymes, um, monitor hormone levels, a- and so forth. So I, I simply can't say whether or not you, um, need to or you don't need to cycle them. Typically, uh, Tongkat ali and maca are not cycled in any regular kind of way that I'm aware of, but, um, again, you really need to check with your doctor if you're going to initiate taking any of these things. Um, and you certainly should do your best to monitor your blood work, as well as subjective measures in evaluating whether or not they're working for you, safe for you, and so forth. The third and final substance/supplement that I want to touch on as it relates to libido is called Tribulus terrestris. So that's T-R-I-B-U-L-U-S, terrestris, T-E-R-R-E-S-T-R-I-S. This is a commonly sold over-the-counter supplement for increasing testosterone for, you know, fitness purposes and, and so on. Whether or not it actually does that to a, um, meaningful degree, uh, isn't clear, but I'm aware of four peer-reviewed studies that were focused on both males and females, um, ranging anywhere from, uh, eighteen years old all the way up to sixty-five plus, a fairly broad age range, um, where people took anywhere from, uh, seven hundred and fifty milligrams per day, divided into three equal doses. So seven hundred and fifty total per day, divided into three equal doses of Tribulus, um, or placebo for a hundred and twenty days. Um, this particular study was focused on females, um, and according to the Female Sexual Function Index questionnaire, um, no significant difference between any of the groups. However, free and bioavailable testosterone increased in the group taking Tribulus terrestris. Total testosterone did not reach statistical significance. So this is sort of the inverse of what we see with maca, where there do seem to be increases in testosterone, which would predict that there would be increase in libido. In this case, in-- this was post-menopausal women. There was no increase in libido. There was an increase in testosterone. I mention it only because there might be instances in which people want to increase their testosterone. It does seem that Tribulus, at least in that population, is capable of doing that. Now, there's a separate study that was done, a double-blind study, uh, lasting anywhere from one to six months, that had a clear and significant increase in libido. Now, this was taking six grams, so that's six, six thousand milligrams of Tribulus root for sixty days, and it did seem to increase various aspects of sexual function. I think more studies are certainly needed, but these three substances/supplements, maca, Tongkat ali, in particular, Indonesian Tongkat ali, and Tribulus, can indeed create significant increases in sexual desire, and in some cases, by adjusting the testosterone and estrogen system, in some cases, not by adjusting the testosterone and estrogen system, again, pointing to the complexity of neurochemicals and features that adjust things like libido, AKA desire. So we covered a lot of material today related to desire, love, and attachment, and yet I acknowledge that it is not exhaustive of the vast landscape that is the psychology and biology of desire, love, and attachment. Nonetheless, I hope that you found the information interesting and hopefully actionable in some cases toward the relationships of your past, of present, and potentially for the relationships of your future. Thank you for joining me for today's discussion about desire, love, and attachment. And last but certainly not least, thank you for your interest in science. [upbeat music]
Install uListen to search the full transcript and get AI-powered insights
Get Full TranscriptGet more from every podcast
AI summaries, searchable transcripts, and fact-checking. Free forever.
Add to Chrome