How to Use Cold & Heat Exposure to Improve Your Health | Dr. Susanna Søberg

How to Use Cold & Heat Exposure to Improve Your Health | Dr. Susanna Søberg

Huberman LabMay 15, 20232h 30m

Andrew Huberman (host), Susanna Søberg (guest), Narrator

Physiology of deliberate cold exposure and the cold shock responseBrown adipose tissue (brown fat): location, function, and plasticityHormetic stress, metabolism, and insulin sensitivityCold vs. heat: winter swimming plus sauna and the Søberg ProtocolSympathetic vs. parasympathetic activation, catecholamines, and moodPractical protocols: duration, temperature, frequency, and safetyIndividual variation: gender differences, adaptation, and edge cases (e.g., no measurable brown fat)

In this episode of Huberman Lab, featuring Andrew Huberman and Susanna Søberg, How to Use Cold & Heat Exposure to Improve Your Health | Dr. Susanna Søberg explores cold And Heat: Simple Weekly Habits To Supercharge Metabolism, Mood Andrew Huberman interviews Dr. Susanna Søberg about how deliberate cold and heat exposure reshape metabolism, brown fat activity, cardiovascular health, and brain chemistry. Drawing from her 2021 Cell Reports Medicine study and related work, Søberg explains how brief, uncomfortable temperature stress drives powerful hormetic adaptations. They outline practical thresholds—about 11 minutes of cold and 57 minutes of sauna per week—that improve insulin sensitivity, blood pressure, brown fat function, and resilience to cold. The conversation also covers mechanisms (sympathetic activation, catecholamines, brown fat pathways), safe protocols, individual differences, and why ending on cold (the “Søberg Principle”) extends the metabolic benefits for hours afterward.

Cold And Heat: Simple Weekly Habits To Supercharge Metabolism, Mood

Andrew Huberman interviews Dr. Susanna Søberg about how deliberate cold and heat exposure reshape metabolism, brown fat activity, cardiovascular health, and brain chemistry. Drawing from her 2021 Cell Reports Medicine study and related work, Søberg explains how brief, uncomfortable temperature stress drives powerful hormetic adaptations. They outline practical thresholds—about 11 minutes of cold and 57 minutes of sauna per week—that improve insulin sensitivity, blood pressure, brown fat function, and resilience to cold. The conversation also covers mechanisms (sympathetic activation, catecholamines, brown fat pathways), safe protocols, individual differences, and why ending on cold (the “Søberg Principle”) extends the metabolic benefits for hours afterward.

Key Takeaways

You Need Surprisingly Little Cold and Heat to Get Big Benefits

In Søberg’s winter-swimmer study, participants averaged a total of ~11 minutes of cold-water immersion and ~57 minutes of sauna per week, split across 2–3 sessions (each session: 1–2 minutes in 2–12°C water, then 10–15 minutes at ~80°C sauna, repeated three cold dips and two sauna bouts, ending on cold). ...

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The Goal Is Discomfort and Contrast, Not Extreme Temperatures

Cold and heat act as hormetic stressors: mild, time-limited challenges that trigger adaptive responses. ...

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Brown Fat Is Plastic, Trainable, and Central to Metabolic Health

Brown adipose tissue (BAT) is a mitochondria-dense, thermogenic fat depot located mainly in the supraclavicular region, along the spine, and near large vessels. ...

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Ending on Cold Extends Thermogenic and Neurochemical Benefits

After cold immersion, blood vessels constricted in the cold reopen, leading to an ‘afterdrop’—core temperature continues to fall briefly as cooled blood returns from the periphery. ...

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Cold Exposure Rapidly Boosts Catecholamines and Can Improve Mood

Immersion up to the neck in cold water triggers a strong sympathetic response: heart rate and blood pressure spike, and catecholamines (norepinephrine, epinephrine, dopamine) surge in the brain and body. ...

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Women and Smaller-Bodied People Are Colder but Also Highly Trainable

Women, on average, have more brown fat than men but colder hands, feet, and peripheral skin, and are thermally comfortable at ~24°C versus ~22°C for men. ...

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Cold and Heat Likely Lower Systemic Inflammation, Supporting Brain and Body

In Søberg’s work and others, repeated cold and heat exposures increase IL-6 acutely along with anti-inflammatory IL-10, and are associated over seasons with lower blood pressure, resting heart rate, and improved insulin sensitivity in middle-aged adults. ...

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Notable Quotes

As long as you get uncomfortably cold, it's cold enough.

Dr. Susanna Søberg

You shouldn’t think about cold water immersion as something that is comfortable. It should be hard, because that’s the point of it.

Dr. Susanna Søberg

Brown fat is like your first responder in the body to keep your temperature up.

Dr. Susanna Søberg

If you end on the cold, you have an exercise for your body going on for hours afterwards.

Dr. Susanna Søberg

We don’t need extreme exposure. We need brief, repeated exposure to different temperatures to keep our cells on their toes.

Dr. Susanna Søberg

Questions Answered in This Episode

Your study identified roughly 11 minutes of cold and 57 minutes of sauna per week as effective thresholds. If someone can only access a cold shower and no sauna, how would you modify that weekly dose and bout structure to get as close as possible to your winter-swimming results?

Andrew Huberman interviews Dr. ...

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You mentioned that women have more brown fat but are generally colder at the periphery and comfortable at higher ambient temperatures than men. Based on your unpublished mixed-sex study, are you seeing any indications that optimal cold and heat protocols should differ systematically between men and women?

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In your anecdote about the winter swimmer with no measurable brown fat, his shivering was much more intense and he resembled controls metabolically. Do you think there may be a subpopulation of people who rely primarily on muscle thermogenesis instead of BAT, and should their protocols or safety limits differ?

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You alluded to IL-6 and IL-10 shifts and the potential to lower chronic inflammation with repeated temperature stress. If someone has an inflammatory or autoimmune condition, what would you need to see in the data before confidently recommending a specific cold/heat protocol as an adjunct to their medical care?

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Traditional Scandinavian practices include putting babies to sleep outside in winter and encouraging moderate under- and overdressing seasonally. If a modern city wanted to build ‘temperature hormesis’ back into public health guidelines, what concrete, low-risk environmental or lifestyle policies would you prioritize first?

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Transcript Preview

Andrew Huberman

(music plays) Welcome to the Huberman Lab Podcast, where we discuss science and science-based tools for everyday life. I'm Andrew Huberman, and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine. Today, my guest is Dr. Susanna Søberg. Dr. Susanna Søberg completed her doctoral thesis work at the Center of Inflammation and Metabolism and the Center for Physical Activity Research at the University of Copenhagen in Denmark. Her research has focused on how deliberate cold exposure and deliberate heat exposure can be used to enhance human metabolism. She is the first author of a seminal study which discovered the minimum thresholds for deliberate heat and deliberate cold exposure for increasing brown fat thermogenesis, which is essentially a mode of increasing heat production and metabolism in the body, and for establishing actionable protocols that can be used outside of the laboratory to improve metabolism and human health. Dr. Søberg's research was published in the journal Cell Reports Metabolism in 2021, adding to a long and important history of research focusing on the role of cold and the role of heat in altering various aspects of the body's physiology, including hormone health, metabolism, and changes in neurotransmitters such as dopamine and epinephrine. In fact, today's discussion with Dr. Søberg focuses on the role of deliberate heat and deliberate cold exposure on metabolism, but it also includes discussion of the effects of cold and heat on things like neurotransmitter production, namely dopamine and epinephrine and norepinephrine, the so-called catacholamines which strongly impact mood and metabolism. In addition, Dr. Søberg answers many common questions about deliberate cold and deliberate heat exposure, including, for instance, the difference between cold showers versus cold immersion up to the neck versus total body cold immersion, including whether or not going back and forth between heat and cold changes fundamentally the way that heat and cold impact the metabolism, hormones, and neurotransmitter production. And we talk about almost every single nuance and variation on deliberate cold and deliberate heat exposure protocols as it relates to the underlying science, in particular how cold receptors at the level of the skin are impacted versus cold reception and perception at the level of the brain, and how all of that impacts systems of the brain and body relating to mental health, physical health, and performance. Based on her scientific research and academic training, as well as her understanding and use of deliberate heat and deliberate cold exposure protocols, Dr. Søberg is considered one of the world's leading experts on these topics. In fact, she is the author of a recent book entitled Winter Swimming, which is, I have to say, a terrific book because it breaks down chapter by chapter the different aspects of deliberate heat and deliberate cold into its various constituent parts, including cold acclimization, the cold shock response, dangers and safeties of cold water, the impact of cold and the impact of heat on various aspects of human health, as well as specifics relating to sauna versus ice versus cold swimming, showers, et cetera. It's a very thorough read and a very easy and accessible read that, if you are interested in deliberate cold or deliberate heat exposure or both, will allow you to embrace those protocols with the greatest degree of confidence that you're going to obtain the specific endpoints that you're interested in, and to do so safely. Before we begin, I'd like to emphasize that this podcast is separate from my teaching and research roles at Stanford. It is, however, part of my desire and effort to bring zero cost to consumer information about science and science-related tools to the general public. In keeping with that theme, I'd like to thank the sponsors of today's podcast. Our first sponsor is Plunge. Plunge makes what I believe is the most versatile at-home self-cooling cold plunge for deliberate cold exposure. I've talked numerous times on this podcast about the many benefits of deliberate cold exposure, and indeed, today's episode is focused entirely on the benefits and the science of deliberate cold exposure. Plunge uses a powerful cooling filtration and sanitation unit to give you access to deliberate cold exposure in clean water whenever you want. As we will discuss during today's episode with Dr. Susanna Søberg, deliberate cold exposure, especially deliberate cold exposure done up to the neck in water, can be used to achieve a number of important endpoints related to mental health, physical health, and performance. I've been using a Plunge for more than two years now, and I can tell you that it makes it very easy to get your deliberate cold exposure at home. It doesn't require much cleaning. In fact, it's very easy to keep clean, which is essential. You don't want bacteria and other things growing in your cold plunge. Basically, everything about the Plunge is made easy so that anyone, including myself, can get their deliberate cold exposure on a regular basis at home. If you're interested in getting a Plunge, you can go to Plunge, spell P-L-U-N-G-E, .com/huberman and get $150 off your cold Plunge. Again, that's plunge.com/huberman for $150 off. Today's episode is also brought to us by Maui Nui Venison, which I can confidently say is the most nutrient-dense and delicious red meat available. Maui Nui spent nearly a decade building a USDA-certified wild harvesting system to help balance deer populations on the island of Maui. The solution they built turns the proliferation of an invasive species into a wide range of nutrients-dense products, from butcher cuts and organ meats to bone broth and jerky. Their bone broth has an unmatched 25 grams of protein per 100 calories. Several guests on this podcast who are experts in nutrition have pointed to the value of getting at least one gram of quality protein per pound of body weight each day. With Maui Nui, that's very easy to do while eating delicious meals and getting it from a sustainable source. If you would like to try Maui Nui Venison, go to maui nui venison.com/huberman and get 20% off your first order. Again, that's maui nui venison.com/huberman to get 20% off. Today's episode is also brought to us by Thesis. Thesis makes custom nootropics, and nootropics is not a word that I like because it means smart drugs, and the brain doesn't have neural circuits for being smart, rather has neural circuits for focus, neural circuits for task switching, neural circuits for creativity, and on and on. Thesis understands this and designs custom nootropics designed to get your brain and body into a specific state in order to do the mental and/or physical work that's important to you, such as creativity or focus or clarity. If you'd like to try Thesis Nootropics, you simply go to their website...You fill out a brief quiz and they will design a custom starter pack so that you can assess which things work for you more or less well, and then they'll iterate with you over the course of the next few weeks or months to come up with the ideal nootropic kit for your needs. To get your own personalized nootropic starter kit, go online to takethesis.com/huberman. You can take that three-minute quiz, and they'll send you four different formulas to try in your first month. Again, that's takethesis.com/huberman and use the code Huberman at checkout to get 10% off your first box. I'm pleased to announce that I will be hosting two live events in September of 2023. The first live event will take place in Toronto on September 12th. The second live event will take place in Chicago on September 28th. Both live events will include a lecture and a question and answer period and are entitled The Brain Body Contract, during which I will discuss tools and science related to mental health, physical health, and performance, and I should mention that a lot of that content will have absolutely no overlap with content covered previously on the Huberman Lab Podcast or elsewhere. If you're interested in attending either or both of these events, please go to hubermanlab.com/tour and enter the code Huberman to get early access to tickets. Once again, that's hubermanlab.com/tour and use the code Huberman to access tickets. I hope to see you there. And now for my discussion with Dr. Susanna Soberg. Dr. Susanna Soberg, welcome.

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