Joe Rogan Experience #1371 - Andrew Santino
Joe Rogan (host), Andrew Santino (guest), Jamie Vernon (guest), Narrator, Narrator, Narrator, Narrator, Narrator
In this episode of The Joe Rogan Experience, featuring Joe Rogan and Andrew Santino, Joe Rogan Experience #1371 - Andrew Santino explores joe Rogan and Andrew Santino Swap Food Poisoning, Fights, and Fame Stories Joe Rogan and Andrew Santino spend a long-form hang talking about Santino’s brutal food poisoning episode on a plane, using it as a launchpad into health, diet, food safety, and processed products like Impossible Burgers. They veer into stand-up life, travel hassles, sports injuries, and the physical toll of activities like wrestling, jiu-jitsu, skiing, and calisthenics. The conversation also hits contemporary culture: Trump, political polarization, sex work platforms, cult-like fandoms, social media fakery, and internet conspiracy thinking. Throughout, they mix personal anecdotes, dark humor, and casual health skepticism while repeatedly circling back to discipline, vices, and how comics manage their bodies and careers.
Joe Rogan and Andrew Santino Swap Food Poisoning, Fights, and Fame Stories
Joe Rogan and Andrew Santino spend a long-form hang talking about Santino’s brutal food poisoning episode on a plane, using it as a launchpad into health, diet, food safety, and processed products like Impossible Burgers. They veer into stand-up life, travel hassles, sports injuries, and the physical toll of activities like wrestling, jiu-jitsu, skiing, and calisthenics. The conversation also hits contemporary culture: Trump, political polarization, sex work platforms, cult-like fandoms, social media fakery, and internet conspiracy thinking. Throughout, they mix personal anecdotes, dark humor, and casual health skepticism while repeatedly circling back to discipline, vices, and how comics manage their bodies and careers.
Key Takeaways
Food poisoning can escalate fast, especially while traveling.
Santino goes from feeling normal to blacking out and vomiting uncontrollably on a 5‑hour flight, likely from mishandled vegetables; Rogan notes salad and buttered foods are common food-poisoning vectors and that undigested food in vomit suggests acute rejection.
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Highly processed “plant-based meats” aren’t automatically healthier than real meat.
They discuss a rat study on Impossible Burger’s soy leghemoglobin showing weight and blood toxicity changes, plus the heavy use of processed vegetable oils; Rogan emphasizes that whole foods and simple fats (olive, avocado, coconut oil) are generally safer bets.
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Online sex work platforms are normalizing a safer alternative to street prostitution.
OnlyFans-style services let creators monetize nudity or explicit content directly from home; Rogan and Santino frame this as legally protected, less physically dangerous, and something society will increasingly have to accept rather than moralize away.
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Closed, identity-based groups easily slide into cult-like behavior.
Their hypothetical “Red Boys” example and talk of Proud Boys and influencer ‘Nations/Armies’ show how loyalty, branding, and shared grievance can radicalize members and implicate founders in actions they never directly endorsed.
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Infections from gyms, mats, and shared spaces can be lethal if ignored.
Stories of staph, MRSA, and meningitis—from jiu-jitsu mats, dirty gyms, and water parks—underscore how minor-looking cuts can become systemic infections; they stress immediate medical attention and criticize extreme “only homeopathic” responses.
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Physical disciplines beat equipment when it comes to functional strength.
They admire bar-calisthenics athletes who build elite physiques with pull-ups, dips, and bodyweight work in parks, arguing you can achieve “comic-book” strength and aesthetics without a commercial gym if you’re disciplined.
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Media narratives and polls often rest on shaky or selective foundations.
When discussing impeachment polls and Trump being booed, they question who is actually polled and note that highly engaged outliers often skew perception—reminding listeners to treat single polls or clips as incomplete pictures.
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Notable Quotes
“Food poisoning on a five-hour flight is as bad as you think—it's a horror movie in a metal tube.”
— Andrew Santino (paraphrased from his plane vomiting story)
“You wanna be on a plant-based diet? Eat real foods. The problems start when you try to make it look like meat.”
— Joe Rogan
“The only people that answer polls are assholes.”
— Joe Rogan
“It’s kind of easy to start a cult these days.”
— Andrew Santino
“Out of all the things in nature to have sex with, vagina’s number one.”
— Joe Rogan
Questions Answered in This Episode
How credible is the rat study on Impossible Burger’s key ingredient, and what further research would be needed before drawing strong conclusions for humans?
Joe Rogan and Andrew Santino spend a long-form hang talking about Santino’s brutal food poisoning episode on a plane, using it as a launchpad into health, diet, food safety, and processed products like Impossible Burgers. ...
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Where should society draw the legal and ethical lines around online sex work, especially as platforms like OnlyFans continue to grow?
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Are we underestimating the health risks of everyday environments like gyms and locker rooms, and what practical steps actually reduce staph/MRSA risk?
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At what point does a passionate fan community or ‘nation’ cross the line into a dangerous cult-like group, and who is responsible when that happens?
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Given declining violence trends overall, why do political symbols like MAGA hats now provoke such intense, sometimes violent reactions in public spaces?
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Transcript Preview
... yeah. (glasses clinking) Two, one. (grunts) (drinks splashing)
(laughs)
Hi, Andrew Santino.
(laughs) What's up, Mr. Rogan? This is great, huh?
It's still Sober October.
Still sober.
You can't have real drinks.
No, I'm gonna have s-... I'm gonna... not gonna have real drinks. I'm gonna have this.
You can have some of this.
Cheers. I'll have some of this.
Pineken 0-0. Mm. (swallowing) Ah. It's good, right?
Oh, yeah, it's pretty good.
(grunts) (glass thudding) I know you wanna get fucked up, but you can't. How about that?
(sighs) I'm not gonna, man.
How about that?
I'm not gonna. I need n-... I need time for my stomach to clear out.
Do you think you could do Sober October?
No. You know I can't do that shit.
You can't do it?
No. A month?
A week? How about a week?
I could do a wee-... I could do sober week.
So you could do the first week of Sober October?
Yeah, I could do the v-... The reason-
Maybe, like, the first week this year, and next week-... next year, you do two weeks.
If... I'll do... I could do so-... I could do a sober... I could do a sober month, but October sucks for me. It's my birthday in October.
Oh.
So I don't wanna take it off. You know?
Mm.
Also-
Mm.
... I like drinking too much.
You like it a lot.
I could stop... I could stop weed and-
Yeah?
... anything else. But dr-
Not booze?
No, I can't.
Do you want a drink?
Nah.
I got booze right over there.
No, my tummy's so sensitive still.
Yeah, you're all messed. Let's t-... tell everybody what happened.
(laughs)
(laughs) So, uh, n- no, uh, offense to Hilarities, which is a great comedy club, we stopped there-
Mm-hmm.
... uh, Saturday night after our show in Cleveland. We went over to say hi to our friend, Jessie Mae Peluso, who was headlining there. And what was he... the dude's name?
(sighs) Andrew.
Andrew... Don't... Remember.
I don't remember.
Funny guy.
Yeah.
Anyway, um, so we say hi to them, and they, they graciously, the owners of the club, uh, graciously asked if we were hungry and we said, "Sure, we could eat." They have a nice menu.
Why not?
So I had, uh, the prime rib. It was excellent. And you had a steak with some, uh, vegetables.
That's right. I had a bunch of vegetables on the side.
This is probably around midnight.
Uh-huh.
And then, uh, we get on a plane at, like, 6:00 in the morning. We are, uh, flying back home-
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