What Are The Weirdest Types Of Life? - Carl Zimmer | Modern Wisdom Podcast 394

What Are The Weirdest Types Of Life? - Carl Zimmer | Modern Wisdom Podcast 394

Modern WisdomNov 6, 202157m

Carl Zimmer (guest), Chris Williamson (host)

Why definitions of life and death are inconsistent and controversialAnimal and human perception of life, death, and disorders like Cotard SyndromeCryptobiosis and organisms that blur the line between life and non-life (e.g., tardigrades)Extreme metabolisms and unusual life strategies (snakes, slime molds, fungi-like organisms)Primate thanatology and evolutionary roots of death awareness and ritualWeird and hypothetical life: alien biochemistry, non-water solvents, silicon-based systemsOrigins of life on Earth and the debate over viruses being aliveThe case for a theory of life instead of formal definitions, and historical failures at “life’s edge”

In this episode of Modern Wisdom, featuring Carl Zimmer and Chris Williamson, What Are The Weirdest Types Of Life? - Carl Zimmer | Modern Wisdom Podcast 394 explores carl Zimmer Explores Life’s Strangest Forms And Redefines Being Alive Carl Zimmer and Chris Williamson explore why defining “life” and “death” is so scientifically and philosophically messy, despite how intuitively obvious they seem to humans and other animals.

Carl Zimmer Explores Life’s Strangest Forms And Redefines Being Alive

Carl Zimmer and Chris Williamson explore why defining “life” and “death” is so scientifically and philosophically messy, despite how intuitively obvious they seem to humans and other animals.

They examine edge cases—cryptobiotic tardigrades, shape-shifting snakes, maze‑solving slime molds, death-aware primates, and ambiguous entities like viruses—that challenge standard biological definitions.

The conversation extends to weird possible alien life (silicon, non‑water solvents), competing theories of life’s origins on Earth, and medical complexities like brain death and organ donation.

Zimmer concludes that instead of arguing over static definitions, science needs a true theory of life, akin to how chemistry replaced pre‑modern “definitions” of water with molecular understanding.

Key Takeaways

Definitions of life are fragmented and context-dependent.

Biologists, philosophers, and agencies like NASA all use different working definitions, revealing that “life” serves multiple purposes—from medical decision-making to astrobiology—and resists a single, tidy description.

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Basic life–death recognition is widespread in animals and deeply intuitive in humans.

Species from fish to primates adjust behavior around corpses or biological motion, and humans possess a felt sense of being alive that can break down in rare conditions like Cotard Syndrome, where people insist they are dead.

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Some organisms effectively pause life, challenging metabolism-based definitions.

Cryptobiotic species such as tardigrades can dry out, vitrify their internal components into a protein “glass,” halt detectable metabolism for decades, then fully revive—defying simple alive/dead binaries.

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Intelligence and memory don’t require brains or bodies like ours.

Slime molds, single giant cells without nervous systems, solve mazes, optimize paths between food sources, and use chemical “trails” as an externalized memory, showing that problem-solving is a general feature of life, not just brains.

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Medical definitions of death are partly social and ethical constructs.

The adoption of brain death criteria, driven in part by organ transplantation needs, demonstrates that when biological states are ambiguous, societies negotiate where to draw the line between life and death.

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Viruses sit at the boundary of life and force us to refine our criteria.

They lack self-sustaining metabolism and depend on host cells, yet evolve under Darwinian rules and can carry complex functions like photosynthesis genes, making them central test cases for any serious theory of life.

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A robust theory of life may be more valuable than more definitions.

Zimmer, echoing philosopher Carol Cleland, argues that definitions without a deeper theory are like medieval definitions of water; what’s needed is a unifying framework—potentially informed by alternative and extraterrestrial life—rather than endless semantic battles.

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Notable Quotes

You could argue that we don’t really have a deep conceptual understanding of life either.

Carl Zimmer

Life doesn’t really care about our absolutes that way.

Carl Zimmer

They’re just on pause, and can stay on pause for decades, maybe centuries.

Carl Zimmer (on cryptobiotic tardigrades)

You don’t need a brain to be intelligent because these slime molds are literally solving math problems with no need of a brain.

Carl Zimmer

Don’t try to define life. Definitions are pointless… What we really need is a theory of life.

Carl Zimmer, summarizing philosopher Carol Cleland

Questions Answered in This Episode

If our intuitive sense of being alive is so unreliable (as in Cotard Syndrome), how should that change the way we morally and legally define death?

Carl Zimmer and Chris Williamson explore why defining “life” and “death” is so scientifically and philosophically messy, despite how intuitively obvious they seem to humans and other animals.

Get the full analysis with uListen AI

Do organisms in cryptobiosis, with no detectable metabolism, force us to abandon metabolism as a core criterion for life?

They examine edge cases—cryptobiotic tardigrades, shape-shifting snakes, maze‑solving slime molds, death-aware primates, and ambiguous entities like viruses—that challenge standard biological definitions.

Get the full analysis with uListen AI

Should viruses be formally included within “life” for evolutionary and ecological theory, even if they fail some traditional biochemical definitions?

The conversation extends to weird possible alien life (silicon, non‑water solvents), competing theories of life’s origins on Earth, and medical complexities like brain death and organ donation.

Get the full analysis with uListen AI

How might discovering a truly alien biochemistry—different genes, solvents, or energy systems—reshape our current concepts of biology and evolution?

Zimmer concludes that instead of arguing over static definitions, science needs a true theory of life, akin to how chemistry replaced pre‑modern “definitions” of water with molecular understanding.

Get the full analysis with uListen AI

What would a genuine, testable theory of life need to explain that current ad hoc definitions and checklists cannot?

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Transcript Preview

Carl Zimmer

Let's put it this way. There are other species that can recognize things that are alive and are not alive. That doesn't mean that they have, like, a deep conceptual understanding of life. But, you know, you could argue that we don't really either. (laughs) You can see different behaviors that animals have in response to living and dead things. You can see that, uh, that some animals are, are very good at recognizing biological motion, that is the movement of living things, and can distinguish that from the movement of things, you know, like rocks or something that are moving but are not alive. And that's really important for a lot of species.

Chris Williamson

Carl Zimmer, welcome to the show.

Carl Zimmer

Thanks for having me.

Chris Williamson

It's an interesting thing talking about life and what it constitutes, right? Because I think a lot of people have heard about discussions to do with euthanasia and assisted suicide, and is this person really alive, what does it mean, philosophical arguments to do with is somebody in a coma, uh, discussions around abortion, what constitutes life during, um, childbirth and, and beforehand. And yeah, it's an interesting, an interesting area. It seems like it sort of coalesces a lot of big questions that people have.

Carl Zimmer

Uh, it really does. Um, a- and, but at the same time, uh, for as important as it is, um, there hasn't been really all that much, um, thinking among scientists about, you know, life with a big capital L. I mean, when we talk about life, w- what do we really mean? Um, and so what's really astonishing is that, you know, you can find plenty of definitions of life, uh, in the scientific literature, um, but there are different definitions. And I find if I, if, uh, I start talking about life with a scientist, um, they might very well have a definition and it's different from the one I heard from the last person. Um, so y- you have this situation wh- which is really strange. I mean, imagine like in chemistry people didn't agree on what an atom is. I mean, (laughs) that would be kind of problematic. And yet we're in this situation where scientists who study life, life in different forms, they just, they really don't agree on what it is they're talking about.

Chris Williamson

Why is it so messy?

Carl Zimmer

Um, you know, that's a good question. I think, uh, part of the problem is that, uh, i- is, is that sometimes we're trying to get at different things when we use the same word. So, you know, um, there are these, uh, issues about end of life, you know. So, um, is someone who's on a ventilator, are, are they alive? Um, and so we start to talk about, um, uh, you know, brain death as being sort of the definition of the end of life. Um, but that's really the end of one person's life, um, you know, their state of being alive. Um, whereas other people want to say, "Okay, um, you know, a snake and a tree and me, we, we all have something in common that's different than a rock. Um, what am I gonna call that?" And people will say, "Well, that's life." And so it's a, and so it can be a way of trying to pull things together into s- and trying to figure out what they have in common. Um, but, you know, e- but even then you get yourself into trouble because then, you know, you think you kind of have a nice little category of things that are alive and then someone comes along with something else, like a virus, and then everyone starts yelling all over again. Um, so, so it's, it, it's a, it's marvelously prone to lead to big arguments.

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