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Anthropic Raises $30B from Microsoft & NVIDIA & NVIDIA’s Core Business Faces TPU Threat

Jason Lemkin is one of the leading SaaS investors of the last decade with a portfolio including the likes of Algolia, Talkdesk, Owner, RevenueCat, Saleloft and more. Rory O’Driscoll is a General Partner @ Scale where he has led investments in category leaders such as Bill.com (BILL), Box (BOX), DocuSign (DOCU), and WalkMe (WKME), among others. ----------------------------------------------- Timestamps: 00:00 Intro 01:05 Anthropic's $30BN Investment from Microsoft & NVIDIA 09:57 NVIDIA's Customer Concentration: Bull or Bear 21:27 Google vs. OpenAI: Sam Altman's "War Mode" Memo 35:25 Sierra Hits $100M ARR: Justify $10BN Price? 45:45 Implementation is the Biggest Barrier to Enterprise AI Growth 54:16 Lovable Hits $200M ARR & Rumoured $6BN Round 01:05:17 Is LLM Search Optimisation (GEO) Selling Snake Oil? What AI is a Fraud vs Real? 01:18:30 Figma Market Cap: Is the IPO Market F****** for 2026 01:27:26 Quick-Fire Round ---------------------------------------------------------------------------------------------- Subscribe on Spotify: https://open.spotify.com/show/3j2KMcZ... Subscribe on Apple Podcasts: https://podcasts.apple.com/us/podcast... Follow Harry Stebbings on X: https://x.com/harrystebbings Follow Jason Lemkin on X: https://x.com/jasonlk Follow Rory O’Driscoll on X: https://x.com/rodriscoll Follow 20VC on Instagram: https://www.instagram.com/20vchq Follow 20VC on TikTok: https://www.tiktok.com/@20vc_tok Visit our Website: https://www.20vc.com Subscribe to our Newsletter: https://www.thetwentyminutevc.com/con... ----------------------------------------------- #20vc #harrystebbings #roryodriscoll #jasonlemkin #ai #anthropic #nvidia #samaltman #google #sierra #microsoft #warmode

Rory O’DriscollguestJason LemkinguestHarry Stebbingshost
Nov 27, 20251h 32mWatch on YouTube ↗

Episode Details

EPISODE INFO

Released
November 27, 2025
Duration
1h 32m
Channel
The Twenty Minute VC
Watch on YouTube
▶ Open ↗

EPISODE DESCRIPTION

Jason Lemkin is one of the leading SaaS investors of the last decade with a portfolio including the likes of Algolia, Talkdesk, Owner, RevenueCat, Saleloft and more. Rory O’Driscoll is a General Partner @ Scale where he has led investments in category leaders such as Bill.com (BILL), Box (BOX), DocuSign (DOCU), and WalkMe (WKME), among others. ----------------------------------------------- Timestamps: 00:00 Intro 01:05 Anthropic's $30BN Investment from Microsoft & NVIDIA 09:57 NVIDIA's Customer Concentration: Bull or Bear 21:27 Google vs. OpenAI: Sam Altman's "War Mode" Memo 35:25 Sierra Hits $100M ARR: Justify $10BN Price? 45:45 Implementation is the Biggest Barrier to Enterprise AI Growth 54:16 Lovable Hits $200M ARR & Rumoured $6BN Round 01:05:17 Is LLM Search Optimisation (GEO) Selling Snake Oil? What AI is a Fraud vs Real? 01:18:30 Figma Market Cap: Is the IPO Market F****** for 2026 01:27:26 Quick-Fire Round ---------------------------------------------------------------------------------------------- Subscribe on Spotify: https://open.spotify.com/show/3j2KMcZ... Subscribe on Apple Podcasts: https://podcasts.apple.com/us/podcast... Follow Harry Stebbings on X: https://x.com/harrystebbings Follow Jason Lemkin on X: https://x.com/jasonlk Follow Rory O’Driscoll on X: https://x.com/rodriscoll Follow 20VC on Instagram: https://www.instagram.com/20vchq Follow 20VC on TikTok: https://www.tiktok.com/@20vc_tok Visit our Website: https://www.20vc.com Subscribe to our Newsletter: https://www.thetwentyminutevc.com/con... ----------------------------------------------- #20vc #harrystebbings #roryodriscoll #jasonlemkin #ai #anthropic #nvidia #samaltman #google #sierra #microsoft #warmode

SPEAKERS

  • Rory O’Driscoll

    guest

    Venture investor and panel guest discussing AI infrastructure, markets, and enterprise adoption dynamics.

  • Jason Lemkin

    guest

    SaaS founder/investor behind SaaStr, offering SaaS/AI investing and operating perspectives.

  • Harry Stebbings

    host

    Founder and host of 20VC, leading the discussion and interviewing the panelists.

EPISODE SUMMARY

In this episode of The Twenty Minute VC, featuring Rory O’Driscoll and Jason Lemkin, Anthropic Raises $30B from Microsoft & NVIDIA & NVIDIA’s Core Business Faces TPU Threat explores anthropic funding, NVIDIA concentration risk, and AI startups’ valuation debates today Anthropic’s Microsoft–NVIDIA financing is framed as both a compute pre-buy (round-tripping) and a sign that Big Tech relationships are becoming less exclusive as model competition intensifies.

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