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All-In PodcastAll-In Podcast

E159: The Bestie Awards! Recapping the best and worst of 2023

Jason Calacanis on All-In Bestie Awards 2023: Politics, Business, Science, and Self-Owns.

Jason CalacanishostDavid SackshostChamath PalihapitiyahostDavid Friedberghost
Dec 28, 20231h 22mWatch on YouTube

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WHAT IT’S REALLY ABOUT

All-In Bestie Awards 2023: Politics, Business, Science, and Self-Owns

  1. The hosts of the All-In Podcast hold their fourth annual 'Bestie Awards,' handing out tongue‑in‑cheek accolades for the biggest winners and losers across politics, business, science, tech, and culture in 2023.
  2. They frame 2023 as a year of political upheaval (Trump’s resurgence, DEI backlash, Hamas/Israel, third‑party candidates), business concentration (Magnificent Seven, Microsoft, Uber, NVIDIA), and societal strain (antisemitism, youth malaise, ballooning debt).
  3. Science and tech discussions center on CRISPR’s first FDA‑approved treatment, explosive AI/LLM progress, and room‑temperature superconductor hype, alongside worries about over‑regulation and the need for open-source, locally run AI.
  4. The episode closes with reflections on a turbulent but formative two years, cautious optimism for 2024, and appreciation for the show’s growth, with characteristic humor, roasting, and irreverent banter throughout.

IDEAS WORTH REMEMBERING

5 ideas

Populism and non-traditional candidates reshaped 2023 politics.

Trump’s legal troubles strengthened his GOP lead; RFK Jr., Vivek Ramaswamy, and Dean Phillips showed surprising traction, signaling deep voter dissatisfaction with a Biden–Trump rematch and rising appetite for a viable third party.

DEI and ESG suffered a major legitimacy and capital backlash.

Post–October 7 campus reactions and congressional testimonies, plus shrinking ESG assets, led the hosts to label DEI/ESG the year’s political and business ‘losers,’ arguing consumers and donors are rejecting ideological corporate signaling.

Economic power concentrated further in a few mega-cap companies.

The ‘Magnificent Seven’ drove most equity gains, while Microsoft, Nvidia, Meta, and Novo Nordisk exemplified how strategic bets in AI, gaming, semaglutides, and operational discipline translated into trillions in market cap shifts.

AI progress was explosive and decentralized, heightening both promise and control fears.

From GPT-powered apps and open-source models that run locally to rapid advances in generative media, the hosts see massive productivity upside but stress that offline, open tools are key to resisting overbearing regulation and censorship.

CRISPR’s first FDA approval marks a real-world gene-editing inflection point.

Editing sickle cell patients’ genes is framed as a quietly historic breakthrough, particularly for Black patients, demonstrating that once-hypothetical gene-editing therapies are now clinically and commercially real.

WORDS WORTH SAVING

5 quotes

The biggest political winner was Donald Trump… everything the Dems have done has actually galvanized his support.

— Chamath Palihapitiya

My biggest winner in politics is abortion rights… it’s the Democrats’ only winning issue and they’re putting it on the ballot everywhere.

— David Sacks

America should be a colorblind meritocracy.

— David Sacks

The most important boundary condition to have a sustainable third party is a good name… No Labels is a terrible name.

— Chamath Palihapitiya

As long as we embrace the enlightenment and don’t embrace the dark ages, we stand a shot at keeping progress alive.

— David Friedberg

Read the available transcript
Political winners, losers, and surprises of 2023 (Trump, Saudi Arabia, abortion rights, DEI, RFK Jr., Hamas/Israel)Business winners, losers, and turnarounds (Elon Musk, Magnificent Seven, Microsoft, Uber, Disney, Novo Nordisk, Solana)Macroeconomics and policy (Fed rate pivots, banking crisis, bond market bets, national debt and normalized government spending)Science and technology breakthroughs (CRISPR for sickle cell, AI/LLM acceleration, brain decoding, failed LK-99 superconductivity)Cultural and societal trends (DEI backlash, antisemitism, Ivy League reputational damage, youth mental health and excess deaths)Awards for individuals and institutions (best CEO, best investor, worst company, ‘self-immolation’ for Ivy presidents and Giuliani)Media, memes, and tech adoption (Taylor Swift, key podcasts, viral memes, ChatGPT app, Starlink, open-source local LLMs)

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