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How to Cultivate a Positive, Growth-Oriented Mindset | Dr. Jamil Zaki

In this episode, my guest is Dr. Jamil Zaki, Ph.D., professor of psychology at Stanford University, director of the Stanford Social Neuroscience Laboratory, and the author of the new book Hope for Cynics. We discuss cynicism and its healthier, more adaptive alternative, healthy skepticism, and how embracing healthy skepticism can enhance both our emotional and physical health. We discuss the data on how cynicism affects us as individuals and in relationships, causing lower levels of happiness, poorer physical health, and reduced creativity, trust, and collaboration. He also explains novel data-supported tools that we can use to shift ourselves towards a more informed yet more positive worldview and how to adopt a mindset of “hopeful skepticism” — the ideal stance to navigate life. Dr. Zaki offers listeners a positive, hopeful view of humanity grounded in cutting-edge research from his laboratory and other top laboratories. He also offers science-supported protocols to navigate relationships in person and online better. Access the full show notes for this episode: https://www.hubermanlab.com/episode/dr-jamil-zaki-how-to-cultivate-a-positive-growth-oriented-mindset *Thank you to our sponsors* AG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman Joovv: https://joovv.com/huberman Waking Up: https://wakingup.com/huberman Function: https://functionhealth.com/huberman *Huberman Lab Social & Website* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Dr. Jamil Zaki* Website: https://www.jamil-zaki.com Stanford academic profile: https://profiles.stanford.edu/jamil-zaki Social Neuroscience Laboratory: https://www.ssnl.stanford.edu Hope for Cynics (book): https://www.jamil-zaki.com/hope-for-cynics Articles: https://www.jamil-zaki.com/media X (Personal): https://x.com/zakijam X (Lab): https://x.com/StanfordSNL Instagram: https://www.instagram.com/jamil_zaki_psych LinkedIn: https://www.linkedin.com/in/jamil-zaki-b0b4a9192 *Timestamps* 00:00:00 Dr. Jamil Zaki 00:02:12 Sponsors: Maui Nui, Joovv & Waking Up 00:06:59 Cynicism 00:12:38 Children, Attachment Styles & Cynicism 00:17:29 Cynicism vs. Skepticism, Complexity 00:23:30 Culture Variability & Trust 00:26:28 Sponsor: AG1 00:27:40 Negative Health Outcomes; Cynicism: Perception & Intelligence 00:35:59 Stereotypes, Threats 00:39:48 Cooperative Environments, Collaboration & Trust 00:44:05 Competition, Conflict, Judgement 00:48:46 Cynics, Awe, “Moral Beauty” 00:55:26 Sponsor: Function 00:57:13 Cynicism, Creativity & Workplace 01:04:19 Assessing Cynicism; Assumptions & Opportunities 01:11:11 Social Media & Cynicism, “Mean World Syndrome” 01:18:35 Negativity Bias, Gossip 01:24:03 Social Media & Cynicism, Polarization, “Hopeful Skepticism” 01:32:59 AI, Bias Correction 01:39:05 Tools: Mindset Skepticism; Reciprocity Mindset; Social Savoring 01:46:05 Tools: Leaps of Faith; Forecasting; Encounter Counting 01:51:33 Tool: Testing & Sharing Core Beliefs 01:58:09 Polarization vs. Perceived Polarization, Politics 02:06:06 Challenging Conversations, Questioning Perceptions 02:14:04 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter #HubermanLab #Mindset Disclaimer: https://www.hubermanlab.com/disclaimer

Andrew HubermanhostDr. Jamil Zakiguest
Sep 1, 20242h 16mWatch on YouTube ↗

At a glance

WHAT IT’S REALLY ABOUT

Transforming Cynicism Into Hopeful Skepticism Through Science-Backed Social Tools

  1. Andrew Huberman interviews Stanford psychologist Dr. Jamil Zaki about cynicism, trust, empathy, and how our beliefs about people shape our health, relationships, and society. Zaki defines cynicism as a rigid theory that people are fundamentally selfish and dishonest, contrasting it with adaptive, evidence-seeking skepticism. Drawing on laboratory and real‑world data, he shows that cynicism is correlated with worse mental and physical health, weaker relationships, less creativity, and distorted views of others—yet is glamorized as intelligence and social savvy.
  2. Across studies on attachment, workplaces, politics, and social media, Zaki demonstrates that people systematically underestimate the kindness, trustworthiness, and moderation of others, creating self‑fulfilling cycles of mistrust and polarization. He introduces the concept of "hopeful skepticism"—a scientific, curiosity-driven stance that questions our own negative assumptions and seeks real data about others.
  3. The episode offers concrete tools to reduce cynicism: being skeptical of one’s own cynicism, adopting a reciprocity mindset, practicing social savoring, taking calculated social risks, and deliberately documenting positive social experiences. Zaki argues that by updating our priors with better data, we can improve learning, collaboration, conflict resolution, and even national political discourse.

IDEAS WORTH REMEMBERING

5 ideas

Cynicism is a rigid theory about people, not a sharp form of intelligence

Psychologists define cynicism as the belief that people are fundamentally selfish, greedy, and dishonest, and that kindness is just a thin veneer. Unlike skepticism—which seeks evidence and updates beliefs—cynicism operates like a lawyer defending a pre-decided verdict: it looks for confirming evidence and explains away contradictions. Large-scale data show cynics are *not* more intelligent or socially accurate; in fact, cynicism correlates with lower cognitive performance and worse lie-detection than trustful, evidence-based skepticism.

Cynicism quietly erodes health, happiness, and longevity

Prospective studies following tens of thousands of people show that higher cynicism predicts lower life satisfaction, more depression and loneliness, greater cellular inflammation, higher rates of heart disease, and increased all‑cause mortality. Social support normally buffers stress responses (e.g., lower blood pressure during stressful tasks), but cynics fail to benefit from this buffering even when support is present. Zaki frames cynicism as blocking our ability to “metabolize” social nourishment, leaving people psychologically and physiologically malnourished.

Our environments can make us more or less cynical over time

Cynicism has trait-like stability but is highly shaped by context. A Brazilian study comparing ocean fishermen (who must cooperate in teams) to lake fishermen (who work and compete solo) found that over their careers ocean fishermen became more trusting and trustworthy, while lake fishermen grew less trusting and trustworthy—but both groups were *accurate* about their local environments. Similarly, workplace systems like stack ranking and zero-sum competition reduce trust, risk-taking, and knowledge sharing, thereby harming creativity and group performance.

Negativity bias and media distort our picture of other people

Humans overweight threats and negative information: we remember others’ worst traits, gossip more about selfish acts, and perceive the world as more dangerous than it is. Social media algorithms amplify outrage and moral condemnation, disproportionately surfacing extreme, conflict-oriented voices that are not representative of most people. Classic “mean world syndrome” and newer work on online outrage show we systematically overestimate how selfish, hostile, or extreme “people in general” are, which feeds cycles of mistrust and withdrawal.

We radically misperceive political opponents, fueling unnecessary polarization

Studies show that Democrats and Republicans are wrong about each other’s demographics and policy preferences (e.g., estimates of how rich Republicans are or how many Democrats are LGBTQ), and vastly exaggerate how extreme the other side’s positions are (e.g., imagining fully open vs. fully closed borders). Meta-perception studies find people think the other side hates them *twice* as much as they actually do and is up to *four times* more supportive of political violence than reality. When shown accurate data about the other side’s actual views, people’s hostility and support for anti-democratic or violent measures decline.

WORDS WORTH SAVING

5 quotes

Cynicism is a theory about human beings—the idea that people at their core are selfish, greedy, and dishonest.

Dr. Jamil Zaki

Living a cynical life, making the decision that most people can’t be trusted, stops you from being able to metabolize social calories. It leaves you malnourished in a social way.

Dr. Jamil Zaki

Naivete is trusting people in a credulous, unthinking way. I would say cynicism is mistrusting people in a credulous and unthinking way.

Dr. Jamil Zaki

The average person underestimates the average person.

Dr. Jamil Zaki

We stereotype hope and positivity as rose‑colored glasses, but in fact we’re all wearing soot‑colored glasses all the time.

Dr. Jamil Zaki

Definition and psychology of cynicism vs. skepticismAttachment, early development, and the origins of mistrustHealth, happiness, and performance consequences of cynicismSocial media, news, and the “mean world” / negativity biasWorkplace structures, competition, and creativity/trustPolitical polarization and misperceptions of the “other side”Practical tools to shift from cynicism to hopeful skepticism

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