How to Improve Your Vitality & Heal From Disease | Dr. Mark Hyman

My guest is Dr. Mark Hyman, M.D., a physician and world leader in the field of functional medicine. We discuss a systems-based framework for diagnosing and treating the root causes of disease, rather than simply managing symptoms. We also cover cutting-edge health and longevity tools such as peptides, NAD/NMN, exosomes, proactive blood testing and cancer screening, as well as nutrition, supplementation, detoxification, and strategies for addressing specific diseases and health challenges. This discussion will benefit anyone seeking to improve their vitality or combat specific health concerns. Read the episode show notes: https://go.hubermanlab.com/iKSCqnh *Thank you to our sponsors* AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman ROKA: https://roka.com/huberman *Dr. Mark Hyman* Website: https://drhyman.com UltraWellness Center: https://www.ultrawellnesscenter.com Books: https://drhyman.com/pages/about-dr-hyman Newsletter: https://drhyman.com/pages/longevity Podcast: https://drhyman.com/blogs/content/tagged/podcast Function Health: https://www.functionhealth.com Facebook: https://www.facebook.com/drmarkhyman Instagram: https://www.instagram.com/drmarkhyman YouTube: https://www.youtube.com/user/ultrawellness X: https://x.com/drmarkhyman TikTok: https://www.tiktok.com/@drmarkhyman Threads: https://www.threads.net/@drmarkhyman LinkedIn: https://www.linkedin.com/in/drhyman *Timestamps* 00:00:00 Dr. Mark Hyman 00:01:48 Functional Medicine, Chronic Fatigue Syndrome, Mercury; Systems Medicine 00:08:51 Metabolic Psychiatry; Medicine, Creating Health vs Treating Disease 00:12:19 Sponsors: Joovv & Eight Sleep 00:15:06 Wholistic View of Body, Root Causes 00:19:48 Medicine & Research; “Exposome”, Impediments & Ingredients for Health, Whole Foods 00:26:30 Seed Oils, Starch & Sugar, Ultra-Processed Foods; Obesity Rise 00:36:27 Sponsors: Function & ROKA 00:40:05 Tool: Ingredients for Health, Personalization; Multimodal Approach 00:46:25 Essential Supplements, Omega-3s, Vitamin D3, Multivitamin, Iodine, Methylated B12 00:56:54 Supplements & Traditional Medicine; Limited Budget & Nutrition 01:02:54 Air, Tool: Air Filters; Tap Water Filter; Tool: Health, Expense & Whole Foods 01:09:03 Food Industrialization, Processed Foods 01:14:23 Sponsor: AG1 01:16:18 Declining American Health & Nutrition, Politics, MAHA 01:26:03 Toxins, Food Additives, Generally Recognized As Safe (GRAS) 01:29:25 SNAP Program & Soda, Food Industry & Lobbying 01:36:58 Big Food, Company Consolidation, Nutrition Labels 01:44:21 GLP-1 Agonists, Doses, Risks; Food as Medicine, Ketogenic Diet 01:51:29 Cancer, Diets & Alcohol 01:54:03 Blood Markers, ApoB, Cholesterol, Tool: Test Don’t Guess, Individualization 02:02:54 Mercury; Tool: Detoxification, Sulforaphane, N-Acetylcysteine (NAC) 02:04:56 Endocrine Disrupting Chemicals, Fertility, Tool: Hormone Panels; Heavy Metals 02:11:36 Upregulate Detox Pathways, Gut Cleanse, Tools: Cilantro Juice, Fiber 02:17:08 Peptides, PT-141 (Vyleesi), BPC-157, Thymosin Alpha-1; Risks, Cycling 02:22:03 Cancer Screening, Data & Personalized Health; Alzheimer’s Disease 02:30:45 Longevity Switches, NAD, NMN; Exosomes, Stem Cells 02:39:50 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter #HubermanLab #Science #Health Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

Andrew HubermanhostDr. Mark Hymanguest

Apr 14, 20252h 42mWatch on YouTube ↗

EPISODE INFO

Released: April 14, 2025
Duration: 2h 42m
Channel: Huberman Lab
Watch on YouTube: ▶ Open ↗

EPISODE DESCRIPTION

My guest is Dr. Mark Hyman, M.D., a physician and world leader in the field of functional medicine. We discuss a systems-based framework for diagnosing and treating the root causes of disease, rather than simply managing symptoms. We also cover cutting-edge health and longevity tools such as peptides, NAD/NMN, exosomes, proactive blood testing and cancer screening, as well as nutrition, supplementation, detoxification, and strategies for addressing specific diseases and health challenges. This discussion will benefit anyone seeking to improve their vitality or combat specific health concerns. Read the episode show notes: https://go.hubermanlab.com/iKSCqnh *Thank you to our sponsors* AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman ROKA: https://roka.com/huberman *Dr. Mark Hyman* Website: https://drhyman.com UltraWellness Center: https://www.ultrawellnesscenter.com Books: https://drhyman.com/pages/about-dr-hyman Newsletter: https://drhyman.com/pages/longevity Podcast: https://drhyman.com/blogs/content/tagged/podcast Function Health: https://www.functionhealth.com Facebook: https://www.facebook.com/drmarkhyman Instagram: https://www.instagram.com/drmarkhyman YouTube: https://www.youtube.com/user/ultrawellness X: https://x.com/drmarkhyman TikTok: https://www.tiktok.com/@drmarkhyman Threads: https://www.threads.net/@drmarkhyman LinkedIn: https://www.linkedin.com/in/drhyman *Timestamps* 00:00:00 Dr. Mark Hyman 00:01:48 Functional Medicine, Chronic Fatigue Syndrome, Mercury; Systems Medicine 00:08:51 Metabolic Psychiatry; Medicine, Creating Health vs Treating Disease 00:12:19 Sponsors: Joovv & Eight Sleep 00:15:06 Wholistic View of Body, Root Causes 00:19:48 Medicine & Research; “Exposome”, Impediments & Ingredients for Health, Whole Foods 00:26:30 Seed Oils, Starch & Sugar, Ultra-Processed Foods; Obesity Rise 00:36:27 Sponsors: Function & ROKA 00:40:05 Tool: Ingredients for Health, Personalization; Multimodal Approach 00:46:25 Essential Supplements, Omega-3s, Vitamin D3, Multivitamin, Iodine, Methylated B12 00:56:54 Supplements & Traditional Medicine; Limited Budget & Nutrition 01:02:54 Air, Tool: Air Filters; Tap Water Filter; Tool: Health, Expense & Whole Foods 01:09:03 Food Industrialization, Processed Foods 01:14:23 Sponsor: AG1 01:16:18 Declining American Health & Nutrition, Politics, MAHA 01:26:03 Toxins, Food Additives, Generally Recognized As Safe (GRAS) 01:29:25 SNAP Program & Soda, Food Industry & Lobbying 01:36:58 Big Food, Company Consolidation, Nutrition Labels 01:44:21 GLP-1 Agonists, Doses, Risks; Food as Medicine, Ketogenic Diet 01:51:29 Cancer, Diets & Alcohol 01:54:03 Blood Markers, ApoB, Cholesterol, Tool: Test Don’t Guess, Individualization 02:02:54 Mercury; Tool: Detoxification, Sulforaphane, N-Acetylcysteine (NAC) 02:04:56 Endocrine Disrupting Chemicals, Fertility, Tool: Hormone Panels; Heavy Metals 02:11:36 Upregulate Detox Pathways, Gut Cleanse, Tools: Cilantro Juice, Fiber 02:17:08 Peptides, PT-141 (Vyleesi), BPC-157, Thymosin Alpha-1; Risks, Cycling 02:22:03 Cancer Screening, Data & Personalized Health; Alzheimer’s Disease 02:30:45 Longevity Switches, NAD, NMN; Exosomes, Stem Cells 02:39:50 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter #HubermanLab #Science #Health Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

SPEAKERS

Andrew Huberman
host
Dr. Mark Hyman
guest
Narrator
other

EPISODE SUMMARY

In this episode of Huberman Lab, featuring Andrew Huberman and Dr. Mark Hyman, How to Improve Your Vitality & Heal From Disease | Dr. Mark Hyman explores functional Medicine, Food, And Lab Testing To Reverse Chronic Disease Andrew Huberman and Mark Hyman discuss functional medicine as a systems‑biology approach that targets root causes—diet, toxins, hormones, microbiome, and lifestyle—rather than just naming and drugging diseases. Hyman explains how his own collapse from mercury‑induced chronic fatigue forced him to reverse‑engineer each body system and build a new operating system for clinical medicine. They detail practical nutrition (whole foods, low sugar/starch, cautious fats), core supplements, toxin avoidance and detox pathways, and how to use modern lab testing and wearables to become CEO of one’s own health. They also address GLP‑1 drugs, peptides, NAD, exosomes, and the politics of food and public health, including why big food and captured institutions resist meaningful nutrition reform.

RELATED EPISODES