Alan Aragon on Huberman Lab: How to Lose Fat and Gain Muscle

How total daily protein and MPS triggers drive fat loss and muscle gain together; Aragon covers insulin timing, fasting myths, and calorie distribution.

Andrew HubermanhostAlan Aragonguest

Jul 7, 20252h 34mWatch on YouTube ↗

EPISODE INFO

Released: July 7, 2025
Duration: 2h 34m
Channel: Huberman Lab
Watch on YouTube: ▶ Open ↗

EPISODE DESCRIPTION

My guest is Alan Aragon, a renowned nutrition and fitness expert and researcher known for sharing the strongest evidence-based approaches to fat loss, muscle gain and overall health and fitness. We discuss how to optimize your protein intake, including how much to consume per meal and when, and the facts and myths about the “30-gram rule” and the “anabolic window” following exercise. We also discuss controversial topics such as seed oils, artificial sweeteners, animal vs. plant proteins, training fasted for fat loss and collagen supplementation. Alan Aragon clarifies the most important topics in nutrition and offers valuable time-saving yet extra-effective ways to exercise. He is a true expert in providing data-supported actionable exercise and nutrition protocols for anyone seeking to improve their body composition and health. Episode show notes: https://go.hubermanlab.com/FfBJCje *Thank you to our sponsors* AG1: ⁠https://drinkag1.com/huberman Carbon: ⁠https://joincarbon.com/huberman Wealthfront**: ⁠https://wealthfront.com/huberman David: ⁠https://davidprotein.com/huberman Function: ⁠https://functionhealth.com/huberman **This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. *Follow Huberman Lab* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab X: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Alan Aragon* Website: https://alanaragon.com Monthly Research Review: https://alanaragon.com/aarr/#aarr-pricing-table Flexible Dieting (new book): https://amzn.to/3TVwNHM Books: https://amzn.to/461Lm49 X: https://x.com/TheAlanAragon Instagram: https://www.instagram.com/thealanaragon Threads: https://www.threads.com/@thealanaragon TikTok: https://www.tiktok.com/@thealanaragon Facebook: https://www.facebook.com/alan.aragon.796/ LinkedIn: https://www.linkedin.com/in/alan-aragon *Timestamps* 00:00:00 Alan Aragon 00:02:17 Dietary Protein & Protein Synthesis Limits?, Tool: Post-Resistance Training & Protein Intake (30-50g) 00:09:16 Training Fasted, Post-Exercise Anabolic Window, Tool: Total Daily Protein 00:15:53 Daily Protein Intake, Timing & Exercise, Muscle Strength/Size 00:23:00 Sponsors: Carbon & Wealthfront 00:26:46 Does Fasted Training Increase Body Fat Loss?, Cardio, Individual Flexibility 00:36:53 Dietary Protein & Body Composition 00:38:58 Animal vs Plant Proteins (Whey, Soy, Pea, Quorn), Muscle Size & Strength 00:51:24 Sponsors: AG1 & David 00:54:14 Body Re-Composition, Gain Muscle While Losing Fat?, Tool: Protein Intake & Exercise 01:02:55 Fiber; Starchy Carbohydrates & Fat Loss, Ketogenic Diet 01:10:36 Inflammation, Fat & Macronutrients, Hyper-Palatability; Fish Oil Supplementation 01:16:52 Added Dietary Sugars, Sugar Cravings, Tool: Protein Intake 01:24:03 Artificial Sweeteners (Aspartame, Sucralose, Saccharine, Stevia), Diet Soda, Weight Loss 01:30:16 Sponsor: Function 01:32:04 Caffeine, Exercise & Fat Loss 01:34:53 Alcohol, Red Wine, Sleep, Lifestyle; Quitting Drinking & Stress Resilience 01:44:43 Seed Oils vs Animal Fats, Canola Oil, Olive Oil, Oil Production, Tool: Improve Diet Quality 01:55:50 Butter & Cardiovascular Risk, Saturated Fat, Mediterranean Keto Diet, Testosterone 02:00:43 Menstrual Cycle, Tool: Diet Breaks; Menopause Transition & Body Composition 02:07:04 Collagen Supplementation, Skin Appearance 02:12:44 Supplements: Multivitamins, Vitamin D3, Fish Oil, Creatine, Vitamin C 02:20:03 Resistance & Cardio Training, Tool: Cluster Sets & Super Sets 02:31:35 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter #HubermanLab #Health #FatLoss #MuscleGrowth #Nutrition Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

SPEAKERS

Andrew Huberman
host
Alan Aragon
guest

EPISODE SUMMARY

In this episode of Huberman Lab, featuring Andrew Huberman and Alan Aragon, Alan Aragon on Huberman Lab: How to Lose Fat and Gain Muscle explores evidence-Based Nutrition: Protein, Fat Loss, Muscle Gain, And Flexibility Explained Andrew Huberman and nutrition researcher Alan Aragon unpack evidence-based strategies for fat loss, muscle gain, and long-term health, cutting through common myths about protein limits, anabolic windows, fasted training, carbs, seed oils, sugar, alcohol, and more.

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