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Jay Shetty PodcastJay Shetty Podcast

The SUGAR Expert: Everything You Need To Know About Glucose Spikes (& 5 HACKS TO PREVENT THEM)

Today, Jay welcomes The Glucose Goddess ie. Jessie Inchauspé. Jessie is a French biochemist and New York Times bestselling author. In her books Glucose Revolution and The Glucose Goddess Method, she shares her startling discovery about the essential role of blood sugar in every aspect of our lives, and the surprising hacks to optimize it. In this interview, we discuss: 00:00 Intro 01:01 What Is Glucose? 03:40 Does Your Body NEED Sugar? 05:55 The Hidden Costs of Glucose Spikes 10:57 Change Your Breakfast Habits 15:49 Why Is Sugar Addictive? 20:00 How to Eliminate Post-Meal Cravings 25:32 The Daily Recommended Sugar Intake 30:19 The Surprising Link Between Sleep & Glucose 32:37 How Blood Sugar Levels Affect Mental Health 38:42 Ideal Foods Pre-Workout 42:22 The Benefits of Vinegar 45:21 Put “Clothing” on Your Carbs 48:57 Fruits Are Healthy Until They Gets Processed 52:50 STOP Counting Your Calories 58:17 The Anti-Spike Formula 01:01:15 The Truth About Ozempic 01:04:22 Jessie on Final Five Episode Resources: https://www.instagram.com/glucosegoddess https://twitter.com/glucosegoddesss https://www.tiktok.com/@glucosegoddess_ https://www.amazon.com/Glucose-Revolution-Life-Changing-Power-Balancing/dp/1982179414 https://www.glucosegoddess.com/ https://antispike.com/products/anti-spike-formula-pre-order?view=sl-5DD2E172

Jessie InchauspéguestJay Shettyhost
Mar 18, 20241h 11mWatch on YouTube ↗

Summaries, chapters, transcripts, and FAQs on this page are made by uListen, not YouTube.

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  1. 0:00 – 1:01

    Intro

    1. JI

      The more glucose spikes you have, the faster you age.

    2. JS

      Wow.

    3. JI

      And this shows on your skin, and your organs slowly age. Today, three out of five people are gonna die of an inflammation-based disease. If you want a healthy body, a healthy mind, you need to make sure you're not on a glucose rollercoaster. Your body doesn't care whether sugar came from an orange juice or whether sugar came from a beetroot and is now in a can of Coca-Cola. Those sugar molecules will both lead to a glucose spike.

    4. JS

      Before we jump into this episode, I'd like to invite you to join this community to hear more interviews that will help you become happier, healthier, and more healed. All I want you to do is click on the subscribe button. I love your support. It's incredible to see all your comments, and we're just getting started. I can't wait to go on this journey with you. Thank you so much for subscribing. It means the world to me. The number one health and wellness podcast.

    5. JI

      Jay Shetty.

    6. JS

      Jay Shetty. The one, the only Jay Shetty. [laughs]

  2. 1:01 – 3:40

    What Is Glucose?

    1. JS

      What is glucose, and why is it important to understand it?

    2. JI

      I love this question. So glucose is also called blood sugar, right? And glucose is your body's favorite source of energy. So make a fist right now with your hand. Okay, so as you're doing this, the muscles in your hand are burning glucose to contract. And for everybody listening to us right now, the cells in your brain are currently burning glucose to understand what we're saying, right? Every single part of your body is burning glucose every nanosecond to keep you alive. And as human beings, the main way that we provide this very important glucose to our body is by eating foods, specifically by eating two categories of foods. Starches, so that's bread, pasta, rice, potatoes, oats. And sugars, anything that tastes sweet from an apple to my favorite triple-layered chocolate cake, okay [laughs] ? So we eat starches and sugars, and we give glucose to our body. So you might think, "Okay, I want lots of energy. Who doesn't want energy? So if glucose is my body's energy, I should give my body as much glucose as possible. I should eat as many starches and sugar as, as possible." Well, that's actually not the case. I love to take the image of a plant. Do you have any plants at home?

    3. JS

      Many.

    4. JI

      Okay. So you know that in order to keep a plant alive, you need to give the plant some water, but what happens if you give the plant too much water?

    5. JS

      It dies.

    6. JI

      It dies, exactly. And the human body is similar. Some glucose, everything's going great. Too much glucose, and problems start happening.

    7. JS

      Mm.

    8. JI

      Most of us are giving our bodies too much glucose, and this leads to whole bunch of symptoms: cravings for sweet foods, chronic fatigue, brain fog, inflammation, faster aging, hormonal issues, and then long-term, the development of Type 2 diabetes. So my whole purpose is to teach people how to eat the foods that they love, the starches and the sugars, in a way that's not gonna cause problems.

    9. JS

      Mm. Mm.

    10. JI

      So how do you keep eating the spaghetti and the cookies and the bread in a way that is not going to damage your health?

    11. JS

      Mm-hmm.

    12. JI

      That's the whole thing.

    13. JS

      Mm. And that's what I really appreciate about your work-

    14. JI

      Mm

    15. JS

      ... and why I'm excited about this conversation because I think a lot of us think, "Oh, no, I have to cut things out completely."

    16. JI

      Mm-hmm.

    17. JS

      Or, "Oh, no, I'm gonna have to completely shift everything." And actually, you're saying there's... Maybe that is the case. Actually, let's-

    18. JI

      Well, you could

    19. JS

      ... let's, let's go there.

    20. JI

      You could, right?

    21. JS

      Yeah, let's talk

  3. 3:40 – 5:55

    Does Your Body NEED Sugar?

    1. JS

      about that. Is there a need? What is it that needs to be fully cut out? Are there things that we need to definitely avoid in those two buckets-

    2. JI

      Mm

    3. JS

      ... that you just shaped for us?

    4. JI

      Well, we really don't need sugar. We don't need to eat sweet foods at all. It's really just for pleasure. Your body doesn't need that amount of glucose, that amount of sugar. So when we eat sweet stuff, whether it's fruit or chocolate cake, we're doing it because it releases dopamine in our brain. Dopamine is the pleasure hormone. So sugars we could do without. But listen, I want a chocolate cake for my birthday. I don't wanna eat broccoli for my birthday, you know? And it's all around us. Sugar is delicious. It brings us this pleasure. So of course, if you could completely cut it out, it would be better for your health, but I don't think that's realistic for most people.

    5. JS

      Mm.

    6. JI

      I don't have that kind of willpower.

    7. JS

      [laughs]

    8. JI

      And I haven't seen... You must know people who have completely cut out sugar, but it's quite difficult.

    9. JS

      Yeah.

    10. JI

      What about you? What's your sugar consumption like?

    11. JS

      So I'm an extremist-

    12. JI

      Yeah

    13. JS

      ... which means I either am eating no sugar... So when I was a monk, I didn't eat sugar for three years.

    14. JI

      For sure.

    15. JS

      But then I can easily drop back into eating sugar every day-

    16. JI

      Mm-hmm

    17. JS

      ... because my mother raised me as someone who ate a chocolate bar, a chocolate biscuit, a chocolate yogurt, and a chocolate ice cream every day growing up.

    18. JI

      So you're my chocolate brother.

    19. JS

      Yes.

    20. JI

      [laughs]

    21. JS

      I... When you mentioned that chocolate triple-layered cake-

    22. JI

      You were like, "Yes"

    23. JS

      ... and you post, I'm like, that is my dream.

    24. JI

      Mm.

    25. JS

      And I have had to, through my wife's coaching, through your work, had to develop a healthier relationship with sugar because I believe a few years ago, I was genuinely addicted to sugar.

    26. JI

      Mm.

    27. JS

      And I wanna talk to you about that. And for me, it's taken a lot of retraining, a lot of steps in between, where now I'm back being the extremist where I'm not eating, uh, refined sugars at the moment.

    28. JI

      Yeah.

    29. JS

      But at the same time, I would allow myself on my birthday or an occasion to allow myself to enjoy and indulge.

    30. JI

      Mm-hmm.

  4. 5:55 – 10:57

    The Hidden Costs of Glucose Spikes

    1. JI

      Yeah.

    2. JS

      Talk to us about glucose spikes-

    3. JI

      Mm-hmm

    4. JS

      ... and why are people measuring their glucose levels, what does that show us-

    5. JI

      Yeah

    6. JS

      ... and what are we trying to get our glucose to map at?

    7. JI

      So when we eat a meal or food that contains a lot of glucose, so for example, a chocolate cake is a, is a good option, a g- good example, or a plate of pasta or anything else that's starchy or sweet, when we deliver that glucose very quickly to our body, we experience what's called a glucose spike, which means just a rapid increase in how much glucose is in your body. And if you're wearing a glucose monitor, you will see this. It will look like this mountain that's just rising and rising and rising, and then it crashes. You don't need to wear a glucose monitor to understand the benefits of my work, by the way, but it's a cool visual tool. So what happens in your body when we, we spike? Why is it bad for us? There are three main mechanisms that are going on on a physiological level that make these spikes damaging. The first one has to do with our mitochondria. The mitochondria are the powerhouse of the cell. Most people remember that from biology class. So your mitochondria are these little factories inside your cells that are responsible for turning glucose molecules into energy, okay? They're incredibly important. The problem is when you give them a glucose spike, so when you deliver them a bunch of glucose molecules very quickly, they break down. They kind of go on strike. You know, it's like when you have so much to do on your to-do list that you're just like, "I can't do anything, I have to go nap"?

    8. JS

      [laughs]

    9. JI

      That's the feeling they get. They're, like, overwhelmed by all these glucose molecules, and they cannot do their job properly anymore. And so what happens, you feel this as fatigue. So you keep eating this sugar and these carbs, but you're exhausted.

    10. JS

      Mm.

    11. JI

      You wake up in the morning, you're tired. Going to the grocery store is exhausting. Playing with your kids is draining. Your mitochondria are not functioning properly anymore.

    12. JS

      Mm.

    13. JI

      And that's why one of the main symptoms of having glucose spikes, which most of us have, is this sense of chronic fatigue.

    14. JS

      Mm-hmm.

    15. JI

      Now, the, the second thing that happens in our body when we spike has to do with cooking. So you know if you put something in the oven, like a chicken, and it goes from pink to brown? The chicken has cooked, and the browning process is called glycation. The chicken has glycated. It has-

    16. JS

      Mm

    17. JI

      ... cooked. Now, a human being, from the moment we're born, we're slowly cooking. We're slowly glycating. I know it sounds weird-

    18. JS

      Yeah

    19. JI

      ... but it's true. [laughs] For example, if you look at the cartilage of babies, it's white, but if you look at the cartilage of somebody who's 100 years old, the cartilage is brown.

    20. JS

      Mm.

    21. JI

      We glycate. We brown as we age. And so much so that glycation is actually pretty similar to aging.

    22. JS

      Mm-hmm.

    23. JI

      And then when we're fully glycated, when we're fully cooked, when we're fully aged, we die.

    24. JS

      Mm.

    25. JI

      So glycation is a process that we can't stop. We can't stop aging. You know, there's billionaires trying to reverse aging, but so far they haven't been able to.

    26. JS

      Mm.

    27. JI

      But we can slow it down or speed it up, and glucose spikes have something to do with this.

    28. JS

      Right.

    29. JI

      Glucose and glycation kind of sound s- like similar words. It's because it is the glucose that is doing the glycating.

    30. JS

      The aging.

  5. 10:57 – 15:49

    Change Your Breakfast Habits

    1. JS

      What are some of the hidden places glucose is that we may not see-

    2. JI

      Mm

    3. JS

      ... or may not understand that we can't figure out on a day-to-day basis? Because I feel like-

    4. JI

      Yeah

    5. JS

      ... when I went to that test of the no sugar cereal-

    6. JI

      Mm

    7. JS

      ... in my head, that didn't have glucose, only for me to understand it was the rice that it was made from that was having that impact on me.

    8. JI

      Uh-huh.

    9. JS

      So where, where is... Are there any others that you know that are hidden?

    10. JI

      Actually, breakfast food is usually a top offender, right?

    11. JS

      Right.

    12. JI

      So orange juice, fruit smoothies, breakfast cereal. Even if they say no sugar or low in sugar, that doesn't mean they don't contain glucose.

    13. JS

      Mm.

    14. JI

      It just means they don't contain any table sugar, but they could also contain sugar from fruit, which is, quote-unquote, "natural"-

    15. JS

      Mm-hmm

    16. JI

      ... so it doesn't have to be claimed as an added sugar in a package, right? Breakfast foods, huge, huge, huge offenders. Um, and then kind of, like, funny things that you wouldn't expect, like eating a lot of grapes- [laughs]

    17. JS

      Mm, yeah

    18. JI

      If you eat 50 grapes, that's actually a lot of sugar because the fruit that we eat today has been bred to be extremely high in sugar and concentrated in sugar. But I think breakfast foods are one of the biggest ones. Oh, also dried fruit.

    19. JS

      Mm.

    20. JI

      People don't realize that it's not because something comes from fruit that it's good for you.

    21. JS

      Mm.

    22. JI

      Dried fruit or a fruit smoothie or fruit juice can contain, you know, tens and tens of grams of sugar even though it originally came from a fruit. But your body doesn't care whether sugar came from an orange juice and is now in an orange juice or whether sugar came from a beetroot and is now in a can of Coca-Cola, right?

    23. JS

      Mm-hmm.

    24. JI

      Those sugar molecules will both lead to a glucose spike.

    25. JS

      Yeah, and it's interesting because I think the way we've been trained to have a sweet breakfast... I've switched to savory breakfast last year, and that's something you are a big, big, big proponent of.

    26. JI

      That's a big hack of mine, yes.

    27. JS

      Yeah, talk to us about that switch.

    28. JI

      Well, listen, the glucose spikes that we experience after breakfast is going to control the rest of our day. So if you eat in the morning something that is pure glucose, like most of us do, right? I grew up on orange juice and Nutella crepes-

    29. JS

      [laughs]

    30. JI

      ... so I know.

  6. 15:49 – 20:00

    Why Is Sugar Addictive?

    1. JS

      different things that come with it. Talk to us about why it's so addictive-

    2. JI

      Yeah

    3. JS

      ... obviously beyond the fact that we love the taste of it.

    4. JI

      Uh-huh.

    5. JS

      Why is it so addictive, and how do you-

    6. JI

      How does it cause those symptoms?

    7. JS

      Yeah.

    8. JI

      I think what you're talking about is if somebody goes cold turkey and just-

    9. JS

      Mm-hmm

    10. JI

      ... completely cuts things out, and that's not actually something that I recommend. I think that-

    11. JS

      Mm

    12. JI

      ... again, like I don't have that kind of willpower, um, and I wanna help people improve their health without having to give up the sugar. So even if you delay the sugar from breakfast to after lunch as dessert, you're not gonna get all those withdrawal symptoms. You're still gonna be able to enjoy it and get the dopamine but with less impact on your glucose levels.

    13. JS

      Mm.

    14. JI

      And listen, sugar is addictive, right? And that dopamine is very, very, very, very addictive. And as human beings, eating something sweet is a very easy way to get a hit. Now, what you're talking about can also be due to if somebody completely cuts out carbs, so starches and sugars completely. Let's say from today to tomorrow you cut out all carbs. That can cause issues because if you've been eating carbs your whole life, your body expects these carbs every two to three to four hours-

    15. JS

      Mm

    16. JI

      ... and your body's actually just burning glucose for energy. So all of a sudden you cut off its supply of glucose- And it becomes a little bit stressed out, especially if your body's not used to also burning fat for fuel. In a healthy body, you can switch from burning glucose for energy to burning fat for energy easily. So either you eat glucose and your body gets energy that way, or you're not eating and your body's burning fat. In most of us, we're eating every two to three to four hours some carbs, and so our body doesn't know how to burn fat for fuel anymore. It doesn't have that muscle. So the idea is to train it slowly to be able to do that-

    17. JS

      Mm-hmm

    18. JI

      ... not to just cut out completely the glucose.

    19. JS

      Yeah.

    20. JI

      You know, cut the grass from under the foot too quickly. That's gonna be difficult.

    21. JS

      Yeah, and I think that's one of the biggest challenges, right? Because when it comes to New Year's resolutions or when it comes to changing habits-

    22. JI

      Yeah

    23. JS

      ... we often think we have to go in or out immediately.

    24. JI

      I hate that.

    25. JS

      Yeah.

    26. JI

      And diets, you know?

    27. JS

      Yeah.

    28. JI

      They don't work. They're super stressful. They're actually a, a pretty strong way to control women. Like, I have been from, from the moment I was a teenager, the magazines are telling you, "Lose five pounds in a day," you know, "Lose y- your belly before summer." You're bombarded by these messages that make you feel inadequate if you're not on a diet.

    29. JS

      Mm.

    30. JI

      I mean, it's pretty messed up.

  7. 20:00 – 25:32

    How to Eliminate Post-Meal Cravings

    1. JS

      What should someone eat at 3:00 PM when they're tired?

    2. JI

      [laughs]

    3. JS

      Because everyone has that post-lunch, you know, slump-

    4. JI

      Well, they do

    5. JS

      ... afternoon slump.

    6. JI

      They do, but it actually can go away. If you steady your glucose levels and if you no longer have these spikes, you don't have to feel that post-meal slump anymore.

    7. JS

      Mm.

    8. JI

      'Cause generally that slump comes from your glucose having spiked and now dropping, because after every spike there's a drop, and this drop can make you feel really, really, really tired.

    9. JS

      Mm-hmm.

    10. JI

      So if you feel those symptoms of the post-meal crash, the best thing to do is to start with your breakfast. So have a savory breakfast. Then the second thing I would recommend is at the, at lunchtime, make sure that you start your meals with a specific type of ingredient that is gonna help balance your glucose levels. And before I tell you what that is, I wanna tell you about this amazing research study, Jay. So researchers looked at a meal, and they found that if participants ate the elements of that meal in a specific order, they could reduce the glucose spike of the meal by up to 75%.

    11. JS

      Huge. That's huge.

    12. JI

      Without changing how much they're eating, without changing what they're eating overall, just by changing the order. And when I was in school, I remember, uh, biology teachers telling us, "Oh, when you eat, it all becomes a big soup in your stomach." And so I thought, "How is this possible? How can the order in which you eat the elements of a meal have an impact?" So the research is fantastic. It turns out that when you start your meals with vegetables, the fiber in the veggies when you eat it first has time to coat your upper intestine and create a sort of protective mesh, okay? Like a shield on the walls of your intestine, and that shield then slows down how quickly the rest of the meal is going to access your bloodstream-

    13. JS

      Mm

    14. JI

      ... how quickly the molecules from the rest of the meal are gonna make their way into your bloodstream.

    15. JS

      Mm.

    16. JI

      And so veggies first is this very important hack. Now, the scientists-

    17. JS

      I used to always eat my veggies last.

    18. JI

      Really?

    19. JS

      [laughs]

    20. JI

      Because you hated them?

    21. JS

      Yeah, 'cause right, you eat all the carbs first-

    22. JI

      [laughs]

    23. JS

      ... and all the rest of it. You're like, "Oh, yeah."

    24. JI

      And you know, actually, so when you go to restaurants, they often give you bread at the beginning of the meal.

    25. JS

      Yeah.

    26. JI

      And actually it's pretty smart, so I think there's a whole conspiracy here. Because if you give people some bread at the beginning of your meal, so you're super hungry, you eat the bread. Bread is starch. It turns to glucose. So very quickly you experience this glucose spike, and about 90 minutes later you're crashing.

    27. JS

      Mm.

    28. JI

      And that's when the waiter comes over and is like, "Hi, anybody would like some dessert?" And at that point you're feeling this intense craving for sugar-

    29. JS

      Wow

    30. JI

      ... because of that glucose drop, so you're gonna order dessert.

  8. 25:32 – 30:19

    The Daily Recommended Sugar Intake

    1. JS

      How off is the recommended daily amount of grams of sugar on any given packages, right?

    2. JI

      Mm.

    3. JS

      So if you look at any processed food or any packaged food-

    4. JI

      Yeah

    5. JS

      ... it will say this is 30% of your daily amount.

    6. JI

      Yeah.

    7. JS

      How wrong is the daily amount?

    8. JI

      Well, so the American Heart Association recommends no more than 25 grams of added sugar I think for women, and 50 grams for men, something like that. But we don't need any of this sugar. We don't need to eat any sweet stuff at all. Your body does not need sugar to live. So that is an upper limit-

    9. JS

      Wow

    10. JI

      ... if you will. Yeah. That's an upper limit. It's like saying-

    11. JS

      Yeah, whereas we're seeing it as the basic requirement.

    12. JI

      Yeah. It's like saying, uh, I don't know, three cigarettes are allowed a day. It's like it doesn't mean you should smoke cigarettes.

    13. JS

      Yeah.

    14. JI

      It means like that's the upper limit after which real problems start happening. But it's better to have zero.

    15. JS

      Mm-hmm. Mm-hmm.

    16. JI

      [laughs] But then what these recommendations don't take into account is when are you eating the sugar? Is it first thing in the morning, so you're increasing inflammation, brain fog, increasing risk of diabetes, hurting your mitochondria, having cravings, aging faster, or is it after a lunch that had fiber at the beginning-

    17. JS

      Mm-hmm

    18. JI

      ... of a meal where the impact is gonna be way less hardcore on your health?

    19. JS

      Mm-hmm.

    20. JI

      So if you, if you just keep eating the same amount of sugar as you're eating but you just change when you're eating it-

    21. JS

      That's the first step

    22. JI

      ... you're already gonna see a big impact on your health.

    23. JS

      Mm-hmm.

    24. JI

      Yeah.

    25. JS

      And then second step could be reducing amounts-

    26. JI

      For sure

    27. JS

      ... strictly.

    28. JI

      And naturally, because you're not creating that cycle of addiction-

    29. JS

      Mm

    30. JI

      ... you're gonna have fewer cravings for the sugar anyway.

  9. 30:19 – 32:37

    The Surprising Link Between Sleep & Glucose

    1. JS

      massive impact.

    2. JI

      Mm.

    3. JS

      But how is what you're saying having an impact on the other way?

    4. JI

      Yeah, yeah.

    5. JS

      So I'm saying how these lifestyle choices impact my glucose cravings, but how are our glucose levels impacting our sleep?

    6. JI

      Well, for example, sleep. So sleep and glucose are, go hand-in-hand. And so what you're describing is if you wake up and you haven't slept well, you have more cravings.

    7. JS

      Mm-hmm.

    8. JI

      And you know what else happens, which is kind of unfortunate, is that when your body is tired, it cannot regulate your glucose levels as well.

    9. JS

      Mm-hmm.

    10. JI

      So anything you eat will create a bigger glucose spike.

    11. JS

      Right.

    12. JI

      So for example, if you have that cake on a day when you're rested versus a day when you're super exhausted, the exhausted day, the cake will make a bigger spike. You're eating the same cake-

    13. JS

      Mm

    14. JI

      ... but it's creating a bigger spike.

    15. JS

      Mm.

    16. JI

      Therefore, a bigger crash. Therefore, more cravings.

    17. JS

      Mm.

    18. JI

      And so when we're tired, we tend to crave more sweet foods, and that, that makes a bigger spike and a bigger drop. And then in turn, being on a glucose rollercoaster also makes your sleep that night worse.

    19. JS

      Mm.

    20. JI

      Not as deep, not as restorative. So you start this vicious cycle. Okay, here's what to do to break the cycle. First of all, use the hacks when you wake up. Right? So if you're tired, have a savory breakfast. Second thing to sort of reset your glucose balance is to exercise, even just five minutes. So next time you wake up and you're tired, do five minutes of jumping jacks. Put on a YouTube video, five minutes, you know, exercise. Anything that's gonna get your muscles working is gonna help you manage your glucose levels better-

    21. JS

      Mm, mm

    22. JI

      ... that day. And then as you steady your glucose levels, you will notice you will sleep better. And o- often people will tell me that they used to wake up in the middle of the night with a pounding heart, you know, sweats. That can be because your glucose levels are crashing as you're sleeping.

    23. JS

      Wow.

    24. JI

      Yeah. And that's why in my study, so many people improved their sleep.

    25. JS

      Mm-hmm.

    26. JI

      Not by taking sleeping pills, not by changing what's happening in their bedroom, just by changing how they're eating.

    27. JS

      Yeah.

    28. JI

      Everything is connected, Jay. You cannot just look at one thing in isolation.

    29. JS

      Mm-hmm.

    30. JI

      When you improve your glucose levels, so many systems in your body improve. It's remarkable. So you might be entering this because you want less inflammation or fewer cravings, but then what happens is you realize, "Oh, my skin is better. Oh, I sleep better. Oh, my mood has improved." [laughs] You know? All these amazing side effects. It's really beautiful to

  10. 32:37 – 38:42

    How Blood Sugar Levels Affect Mental Health

    1. JI

      watch.

    2. JS

      Yeah. You mentioned mood there. What's the connection between blood sugar levels and mental health? Because I think-

    3. JI

      Mm

    4. JS

      ... again, even though we are making those connections now, I think often we don't recognize how correlated-

    5. JI

      Yeah

    6. JS

      ... our diet and our mental health is.

    7. JI

      That's the reason I got into this in the first place. So when I was a teenager, I had an accident. I broke my back jumping off a waterfall. Had very intense surgery. I have lots of metal in my back now. And physically I was fine, because you recover fast when you're that young.

    8. JS

      Mm-hmm.

    9. JI

      But then my mental health started going really down the drain. So anxiety, depression, depersonalization. My, I felt like my brain was completely broken. I didn't feel like myself anymore. And I went on a journey to try to understand how to get better, and that's what got me studying biochemistry. That's what got me into genetics. And then almost 10 years after my accident, 10 years of darkness, I finally had my first clue. I was part of a pilot experiment, and during it, I could wear a glucose monitor. And I saw, Jay, that the days where my glucose levels were spiking and dropping a lot, my mental health was worse.

    10. JS

      Mm.

    11. JI

      And the days where my glucose levels were steady, my mental health was so much better.

    12. JS

      Mm.

    13. JI

      And this changed everything for me because I had been completely lost for the better part of a decade, trying to understand what the heck I could do to improve my mental health.

    14. JS

      Mm. Mm.

    15. JI

      And I was lost, let me tell you. And nobody said, "Oh, you should look at your lifestyle." But in that moment, I remember that day, I was feeling one of these episodes come on of depersonalization, which is this horrible mix of brain fog, feeling like a stranger in your own body. I mean, it's terrible. And I scan my glucose monitor, and I see one of the biggest glucose spikes I had ever seen. And so I started putting two and two together. I said, "Wait a minute. Is it possible that this glucose spike is actually causing this episode?" Anyway, so that opened the gates really wide for me. I was like, "Wow, this is fascinating." And I started doing all the research I could, and I, I saw that I wasn't alone, that most people experience glucose spikes on a daily basis even if they don't have diabetes-

    16. JS

      Mm-hmm, mm-hmm

    17. JI

      ... and that these spikes are correlated to all the things we spoke about and to mental health.

    18. JS

      Mm-hmm.

    19. JI

      So as I started managing my glucose levels, my mental health started improving.

    20. JS

      Mm-hmm.

    21. JI

      And so what's the connection? Well, the cells in your brain also use glucose for energy. And so you know those three things I talked about, the mitochondrial damage, the glycation, the inflammation, the insulin? Your brain cells also feel these consequences of spikes. And we don't fully understand how the brain works, but we do understand that when these things happen in the brain, it's not good. [laughs]

    22. JS

      Mm-hmm, mm-hmm.

    23. JI

      We also know that glucose spikes impact tyrosine levels, and tyrosine is an important molecule that regulates our mood. I wanna tell you about another really fun study.

    24. JS

      Yeah, please.

    25. JI

      Can I? Okay.

    26. JS

      Yeah, please. Fascinating.

    27. JI

      So bless these scientists. They're so amazing.

    28. JS

      [laughs]

    29. JI

      Okay, so let me tell you what this study is. So scientists recruited 200 married couples.

    30. JS

      Mm-hmm.

  11. 38:42 – 42:22

    Ideal Foods Pre-Workout

    1. JI

      connected.

    2. JS

      Absolutely. Is there a more ideal food before or after workouts?

    3. JI

      Oh, great question.

    4. JS

      Yeah.

    5. JI

      So this actually brings me to another hack, which is the hack about movement. So as your muscles contract and as you exercise or even as you're just, you know, walking, your muscles are burning glucose for energy.

    6. JS

      Mm.

    7. JI

      And we can use this information to our advantage. So the hack I recommend is after eating one of your meals a day, after one of your meals a day, use your muscles for 10 minutes.

    8. JS

      Mm-hmm.

    9. JI

      Go for a walk, play with your dog, tidy your apartment. I'm a very messy person-

    10. JS

      [laughs]

    11. JI

      ... so I do that one a lot, tidy your apartment. Do some calf raises if you're at your desk at work. Why not go to the gym?

    12. JS

      Mm.

    13. JI

      You know, go weightlift. Because as you do this, your muscles are gonna be using some of the glucose from the meal you just ate.

    14. JS

      Mm-hmm.

    15. JI

      And if you're an athlete and you're doing some very intense exercise, your body's gonna use up most of the glucose from whatever you eat.

    16. JS

      Mm-hmm, mm-hmm.

    17. JI

      So the more you exercise, the more you can eat glucose before or even after actually-

    18. JS

      Right

    19. JI

      ... um, and you'll experience much less of a spike.

    20. JS

      Mm-hmm.

    21. JI

      So i- if you wanna eat a cookie or chocolate cake, before or after workout is actually a pretty good time to do it.

    22. JS

      [laughs]

    23. JI

      That way, a lot of the glucose will go to your muscles instead of-

    24. JS

      Yeah

    25. JI

      ... causing a spike.

    26. JS

      That's what I've been trying to do. So the, the reason I'm asking is for myself, one of the things I struggle with is usually I'll wake up, I'll meditate in the morning, and then I'll drink a tea or something like that, like a w- a warm-

    27. JI

      Yeah

    28. JS

      ... herbal tea, and then I'll go on a hike or I'll go and work out, because I've never really found what to eat before my workout that's great for me. And then when I come back, I'll eat breakfast. I'll have my savory breakfast, and I feel good, and everything feels fine, but I often wonder, could I be doing something better-

    29. JI

      Mm

    30. JS

      ... before I go out on my hike, which, which can be like... It'll be 30 minutes normal and then 30 minutes intense incline.

  12. 42:22 – 45:21

    The Benefits of Vinegar

    1. JS

      So my nutritionist put me onto this a couple of years ago, and I hated it, but then when I saw you were rec- like, it was one of your big pillars-

    2. JI

      Oh, I know what you're about to say

    3. JS

      ... you know what I'm about to say? Yeah.

    4. JI

      Yeah.

    5. JS

      You- Go on.

    6. JI

      Vinegar. [laughs]

    7. JS

      Yes, yeah. So I was drinking a cup of vinegar, like the little whatever, the shot of vinegar.

    8. JI

      Yeah.

    9. JS

      Why a shot of vinegar before?

    10. JI

      Okay, well first of all-

    11. JS

      And tell us why now

    12. JI

      ... a shot is not good.

    13. JS

      Okay.

    14. JI

      You should always dilute it, because if it's a shot it's gonna hurt your teeth's enamel.

    15. JS

      I was literally doing a shot.

    16. JI

      [laughs]

    17. JS

      So I've gotta change that.

    18. JI

      You gotta change that. So-

    19. JS

      And that's a lot easier to dilute, yeah.

    20. JI

      Yeah. Okay. So vinegar contains a wonderful molecule called acetic acid, and acetic acid, when you have some before a meal, is going to slow down how quickly food breaks down into glucose in your body. So it's kind of like slowing down digestion, and this is really, really good. It makes you feel fuller for longer, and the glucose molecules arrive more slowly into your blood, and that's the whole point.

    21. JS

      Mm-hmm.

    22. JI

      So the hack is before a meal that's gonna be high in carbs, have one tablespoon of vinegar in a big glass of water.

    23. JS

      I was not doing that. [laughs]

    24. JI

      Five to 10 minutes. Yeah. Well, I- no wonder you didn't like it if you had it as a shot, like gosh. [laughs] And it can be any type of vinegar, apple cider vinegar, white wine vinegar, cherry vinegar, whatever. You just wanna avoid the very syrupy, like, balsamic glaze.

    25. JS

      Mm-hmm.

    26. JI

      That one's no bueno-

    27. JS

      [laughs]

    28. JI

      ... 'cause that is full of sugar. This is an easy hack, and again, science has shown us that this ingredient that most of us have in our kitchen actually has a wonderful effect on our health.

    29. JS

      Hmm.

    30. JI

      And i- it's been used for millennia. I mean, vinegar's been around forever, but now we understand the science behind it.

  13. 45:21 – 48:57

    Put “Clothing” on Your Carbs

    1. JS

      our snackers?

    2. JI

      Hmm.

    3. JS

      Our snackers that are listening who are saying, "Jesse, I love this advice. I can do that for my meals, but I'm a big snacker-

    4. JI

      Okay

    5. JS

      ... and I turn towards..." I mean, today if you look at it, whether it's a protein bar, but I guess protein bars is such a common go-to snack-

    6. JI

      Yeah

    7. JS

      ... but they have really high sugar.

    8. JI

      It depends on the bar.

    9. JS

      Yeah.

    10. JI

      It really depends. So look at the ingredients always. And if you s- so when you look at the ingredients list on the back of a product, they are ordered by weight.

    11. JS

      Hmm.

    12. JI

      So if the first ingredient says sugar, that means sugar is the most important ingredient in that product.

    13. JS

      Yeah.

    14. JI

      And then they decrease, right, in, in, in weight. So if you see in the first five ingredients of anything, whether it's a protein bar or yogurt, if there's any type of sugar in the first five ingredients, then that product is dessert.

    15. JS

      Hmm.

    16. JI

      Okay? So if it says, like-

    17. JS

      That's such a great tip.

    18. JI

      Yeah. And it doesn't have to say just sugar. It can say something like date puree, honey, dextrose, fruit juice concentrate. It has, uh, in, in Glucose Revolution I have the whole list, but, uh, manufacturers use lots of fancy words-

    19. JS

      Hmm

    20. JI

      ... to not make it sound like just cane sugar.

    21. JS

      Mm-hmm.

    22. JI

      But actually it's just cane sugar.

    23. JS

      Yeah.

    24. JI

      It's all the same molecules.

    25. JS

      Right.

    26. JI

      Right?

    27. JS

      Yeah.

    28. JI

      So sometimes you could take a-

    29. JS

      Your body's not telling the difference, as you said.

    30. JI

      No. No difference. So that's for the protein bars. And then for the snackers, okay, I have a hack-

  14. 48:57 – 52:50

    Fruits Are Healthy Until They Gets Processed

    1. JS

      Yeah, absolutely. In the book you talk about there's some research that says that eating fruit first thing in the morning without any other foods is best for digestion.

    2. JI

      Mm.

    3. JS

      Would eating it as a singular food first thing in the morning impact blood sugar? Like, what's your take on that?

    4. JI

      Well, you know this, this idea of, oh, if you eat fruit as dessert, it's gonna rot in your stomach-

    5. JS

      Mm-hmm

    6. JI

      ... or it's gonna putrefy, that's kind of a urban myth that's been floating around. So if you look at the ideal food order from that-

    7. JS

      Yes

    8. JI

      ... science, you should eat the sugar last.

    9. JS

      Mm-hmm.

    10. JI

      Right? And fruit is also in the sugar category. And so how do you reconcile both of those things? And people have asked me a lot about this concept of, oh, fruit for dessert is gonna rot in your stomach. Turns out there's no scientific evidence to support that. Nothing can rot in your stomach. Nothing can putrefy in your stomach. Sug- uh, sugar eaten last or fruit eaten last does not do that, okay?

    11. JS

      Mm.

    12. JI

      Now, even though most of us think that a piece of fruit is supernatural, they're like, "Oh, a banana, oh, a peach. Like, that's nature's bounty."

    13. JS

      Mm-hmm.

    14. JI

      Turns out, Jay, the fruit that we find today in supermarkets is actually not natural.

    15. JS

      Mm.

    16. JI

      Humans are very good at breeding stuff. So humans have bred gray wolves into Chihuahuas.

    17. JS

      [laughs]

    18. JI

      Right?

    19. JS

      Yeah, yeah.

    20. JI

      And loads of other-

    21. JS

      Yes

    22. JI

      ... breeds of dogs.

    23. JS

      Yeah.

    24. JI

      We've also bred our fruit-

    25. JS

      Mm

    26. JI

      ... and our plants to be very sweet-

    27. JS

      Mm-hmm

    28. JI

      ... and full of sugar.

    29. JS

      Mm-hmm.

    30. JI

      If you compare a banana from today to an ancestral banana, they look nothing alike.

  15. 52:50 – 58:17

    STOP Counting Your Calories

    1. JS

      ... it's really tough. Uh, one of your other hacks, uh, is stop counting calories.

    2. JI

      Yeah

    3. JS

      And I wanted to talk about that because I think that's what all of us do.

    4. JI

      [laughs]

    5. JS

      And again, that, again, the recommended 2,000 for women and 2,500-

    6. JI

      Yeah

    7. JS

      ... for men seems to be, like, such a big figure that we focus our whole diet plans-

    8. JI

      Uh-huh

    9. JS

      ... on and lives on.

    10. JI

      I love this question. Do you know, Jay, how people used to measure the amount of calories in a food?

    11. JS

      No, I don't know.

    12. JI

      Okay. So if they wanted to measure the amount of calories in a donut, here's what they used to do. They would put the donut in a little box, and they would put this box in a bigger, like an aquarium, like a, a big basin of water, okay? They'd put the donut box at the bottom of the aquarium, and then they would light the donut inside the box on fire. The donut would burn, and then they would measure by how many degrees the water in the aquarium increased.

    13. JS

      Oh my gosh.

    14. JI

      So... And that would give you the number of calories in the donut.

    15. JS

      Wow.

    16. JI

      The calories is just a measure of how much heat-

    17. JS

      Mm

    18. JI

      ... is given up when something is burned.

    19. JS

      Mm.

    20. JI

      So if you were to put an avocado in that box and burn it, it might increase the water temperature around it by the exact same number of degrees. Therefore, you would say this donut and this avocado have the same number of calories.

    21. JS

      Mm.

    22. JI

      Now, it seems pretty obvious-

    23. JS

      Yeah

    24. JI

      ... that this is kind of a silly way to measure food. It's almost like saying, "Oh, this book and this book have the same number of pages."

    25. JS

      Pages, yeah.

    26. JI

      "Therefore, they're the same book."

    27. JS

      Yeah.

    28. JI

      This is not the case, right?

    29. JS

      Totally.

    30. JI

      My book and your book might have the same number of pages, but they're not about the same topic, they're not from the same author, they don't give you the same information, don't give you the same emotion, right? And so if we just talk about foods based on how many calories they contain, we're missing what's actually key.

  16. 58:17 – 1:01:15

    The Anti-Spike Formula

    1. JS

      Jessie, we've talked about so many things today, but one thing I wanted to ask you about was the use of supplements.

    2. JI

      Mm.

    3. JS

      I take a lot of supplements every day. I've felt better because of them.

    4. JI

      Mm.

    5. JS

      It's had a big impact on my personal life. And I was always someone who was playing around. I think supplements are also things that you have to test and experiment and see what works for you as a combination.

    6. JI

      Yeah.

    7. JS

      What's your take on supplements?

    8. JI

      Well, I know supplements in the glucose space, right? And I, I can't comment on all the other stuff. I'm sure there's great things for other stuff you're trying to optimize. But when it comes to glucose... So people often ask me, "Instead of doing the vinegar hack, can I take a vinegar gummy?"

    9. JS

      Mm-hmm.

    10. JI

      "When I can't have a veggie starter, can I take fiber pills? My dad has diabetes, doesn't wanna change his diet. What can I give him?" And I spent the last few years researching extensively this space, and what are some cool molecules that could actually help your glucose levels? Unfortunately, what's on the market today At worst, actually contains sugar and creates a glucose spike under the guise of gonna help you with your glucose levels, and that's just so annoying to me. And there's some good stuff out there, but I've actually created something incredible that is the best thing on the market if you want to help your journey to steady glucose with a supplement.

    11. JS

      Mm-hmm.

    12. JI

      Now, I'll explain what it is, but I don't want people to think this is a magic pill. You should do the food hacks first and foremost, okay? That is gonna have the biggest, most powerful impact on your health.

    13. JS

      Mm-hmm.

    14. JI

      But a supplement can also help. So I've identified four plants, Jay, that have existed forever-

    15. JS

      Mm-hmm

    16. JI

      ... but that recent science has shown have an incredible impact on our glucose levels. These are white mulberry leaf, lemon extract, cinnamon, and antioxidants from green vegetables.

    17. JS

      Mm-hmm.

    18. JI

      I've put them all together into a capsule. You take it before a meal-

    19. JS

      Mm-hmm

    20. JI

      ... and it reduces the glucose spike of your meal by up to 40%.

    21. JS

      Wow.

    22. JI

      And this is more powerful than vinegar, which was up to 30%.

    23. JS

      I want it.

    24. JI

      I know.

    25. JS

      Give it to me now.

    26. JI

      I got some in my bag for you.

    27. JS

      Okay, good. [laughs] I'm, Jay, I'm being serious.

    28. JI

      I've got some.

    29. JS

      Yeah.

    30. JI

      So if you want extra help, this is the thing you need. It's called Anti-Spike Formula. You can find it on my website, antispike.com. And it not only has this immediate impact on the glucose spike of a meal, it also builds up benefit over time.

  17. 1:01:15 – 1:04:22

    The Truth About Ozempic

    1. JS

      your take on Ozempic? I mean, based on-

    2. JI

      Mm

    3. JS

      ... what you just mentioned there, what's been your assessment of it? I'm sure you've seen people who are on it.

    4. JI

      Yeah. Listen, I think for a lot of people it's been kind of a godsend. Um, they've really struggled their whole life with their weight, and for some people, that's their objective, right?

    5. JS

      Mm-hmm.

    6. JI

      So whether you take it or you don't take it, it's not m- my place to judge. But what I've found, Jay, is that if you think about it, this craze has shown us that we live in a society in which our food system is so toxic that we need to take a pill to prevent us from eating the food around us.

    7. JS

      Mm.

    8. JI

      Do you understand how sad that is?

    9. JS

      Mm.

    10. JI

      So I just feel a bit worried and a bit disheartened that we've gone to, we've gone to that place. And also, when people lose weight on Ozempic, they don't just lose fat, they also lose muscle mass.

    11. JS

      Mm.

    12. JI

      And so when you stop taking Ozempic and if you, um, gain weight back, you often just gain fat back.

    13. JS

      Mm.

    14. JI

      And so overall, you're in a worse place. So whether or not you take it, it's important to learn my hacks.

    15. JS

      Mm-hmm.

    16. JI

      So that way-

    17. JS

      Sustain it

    18. JI

      ... when you stop it, you sustain it, right?

    19. JS

      Mm.

    20. JI

      But, um, yeah. I mean, wow. Wow, what can I say?

    21. JS

      [laughs]

    22. JI

      Crazy world we live in.

    23. JS

      Yeah, absolutely.

    24. JI

      Yeah.

    25. JS

      And I appreciate you touching on that cultural challenge that we have-

    26. JI

      Mm

    27. JS

      ... on a number of parts in our conversation, and I really think that that's at the heart of a lot of what you're saying is that everyone out there who's listening right now who feels like they don't like the way they eat, they don't like what they eat, they judge their body, they look at the mirror first thing in the morning and criticize themselves, it all comes from programming and conditioning.

    28. JI

      It's not your fault.

    29. JS

      It's not your fault.

    30. JI

      No.

  18. 1:04:22 – 1:11:10

    Jessie on Final Five

    1. JS

      And Jessie, we end every conversation with a Final Five, which is our Fast Five on the podcast. And, uh, I'm excited to, uh, see what you answer.

    2. JI

      Yay.

    3. JS

      So they have to be answered in one word to one sentence maximum.

    4. JI

      Got it.

    5. JS

      So Jessie, here are your Final Five. The first question is, what is the best advice you've ever heard or received when it comes to health?

    6. JI

      Symptoms are messages.

    7. JS

      Hm. I'm gonna let you expand 'cause I like that.

    8. JI

      Okay.

    9. JS

      Yeah.

    10. JI

      If you feel symptoms from acne to psoriasis to infertility to brain fog, these are not something to suppress. They are messages. They are your body trying to communicate with you, to tell you, "Hey, there's something wrong. I need your help."

    11. JS

      Mm.

    12. JI

      Don't suppress, don't feel bad about the symptoms. Flip the script. Talk to your body. Be like, "Okay, why is there all this eczema on my arm? What's going on?" That's inflammation. That's inside. Can I help you? You see what I mean?

    13. JS

      Mm.

    14. JI

      So symptoms are messages.

    15. JS

      How, how do you think we often process symptoms instead of as messages?

    16. JI

      We- ... think our body is fighting us.

    17. JS

      Mm.

    18. JI

      We're like, "Body, why are you against me?"

    19. JS

      Mm.

    20. JI

      We don't understand it's crying for help.

    21. JS

      Mm.

    22. JI

      It's not against... Your body just wants to keep you alive. Your body's not trying to be annoying, I promise. Your body's trying to keep you alive. [laughs]

    23. JS

      That's so good. That's so good. I love that.

    24. JI

      Yeah.

    25. JS

      Your body is not trying to be annoying. [laughs]

    26. JI

      Yeah. [laughs]

    27. JS

      I love that.

    28. JI

      Yeah.

    29. JS

      No, it's so true.

    30. JI

      And your body's so much smarter than you.

Episode duration: 1:11:10

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