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Episode Details
EPISODE INFO
- Released
- September 11, 2019
- Duration
- 2h 19m
- Channel
- The Joe Rogan Experience
- Watch on YouTube
- ▶ Open ↗
EPISODE DESCRIPTION
David Sinclair, Ph.D., A.O. is a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. His new book "Lifespan: Why We Age And Why We Don't Have To" is now available.
SPEAKERS
Joe Rogan
hostDavid Sinclair
guestNarrator
otherNarrator
otherNarrator
other
EPISODE SUMMARY
In this episode of The Joe Rogan Experience, featuring Joe Rogan and David Sinclair, Joe Rogan Experience #1349 - David Sinclair explores David Sinclair Explains How We Might Slow, Stop, Reverse Aging Harvard longevity researcher David Sinclair joins Joe Rogan to discuss the latest science on why we age and how elements of that process may be slowed or even reversed. They cover drug combinations like metformin, DHEA, and human growth hormone that appear to reduce biological age on the Horvath epigenetic clock, as well as Sinclair’s own regimen of NMN, resveratrol, metformin, and lifestyle interventions. Sinclair explains emerging tools such as epigenetic clocks, senolytic drugs that clear “zombie” cells, and gene therapies that can rejuvenate tissues like the retina in mice. The conversation also weaves in practical issues—exercise, fasting, sleep, diet, alcohol—and broader ethical, medical, and societal questions around extending human healthspan.
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