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Joe Rogan Experience #2419 - John Lisle

John Lisle has a Ph.D. in history from the University of Texas, where he is now a professor of the history of science. His two books on the intelligence community are "The Dirty Tricks Department" and "Project Mind Control: Sidney Gottlieb, the CIA, and the Tragedy of MKULTRA." https://www.johnlislehistorian.com https://us.macmillan.com/books/9781250338747/projectmindcontrol/ Perplexity: Download the app or ask Perplexity anything at https://pplx.ai/rogan. Visible. Live in the know. Join today at https://www.visible.com Don’t miss out on all the action - Download the DraftKings app today! Sign-up at https://dkng.co/rogan or with my promo code ROGAN •GAMBLING PROBLEM? CALL 1-800-GAMBLER, (800) 327-5050 or visit https://gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY).Please Gamble Responsibly. 888-789-7777/visit https://ccpg.org (CT), or visit https://www.mdgamblinghelp.org (MD). 21+ and present in most states. (18+ DC/KY/NH/WY). Void in ONT/OR/NH. Eligibility restrictions apply. On behalf of Boot Hill Casino & Resort (KS). Pass-thru of per wager tax may apply in IL. 1 per new customer. Must register new account to receive reward Token. Must select Token BEFORE placing min. $5 bet to receive $200 in Bonus Bets if your bet wins. Min. -500 odds req. Token and Bonus Bets are single-use and non-withdrawable. Token expires 1/11/26. Bonus Bets expire in 7 days (168 hours). Stake removed from payout. Terms: https://sportsbook.draftkings.com/promos. Ends 1/4/26 at 11:59 PM ET. Sponsored by DK.

John LisleguestJoe Roganhost
Nov 26, 20252h 39mWatch on YouTube ↗

At a glance

WHAT IT’S REALLY ABOUT

CIA’s MKUltra: LSD, mind control, and the psychology of power

  1. Joe Rogan interviews historian John Lisle about his book on Sidney Gottlieb, MKUltra, and the CIA’s mind-control experiments. Lisle traces MKUltra’s origins in World War II OSS “dirty tricks,” truth-drug research, and postwar fears of Soviet brainwashing. They walk through infamous episodes such as Operation Midnight Climax, Canadian psychiatrist Ewen Cameron’s brutal “psychic driving,” and the legal battles that revealed MKUltra’s scope. The conversation widens into how secrecy, weak oversight, and human psychology enable abuse, and how similar manipulation dynamics appear in cults, media, and modern disinformation.

IDEAS WORTH REMEMBERING

5 ideas

MKUltra grew from earlier wartime ‘dirty tricks’ and truth-drug experiments.

World War II OSS projects testing THC-laced cigarettes, disguises, and sabotage created a blueprint that Sidney Gottlieb later mined when tasked with exploring mind control for the CIA.

The CIA outsourced much of MKUltra to reputable institutions using cutouts.

MKUltra contained 149 subprojects, often funneled through front organizations to universities, hospitals, and prisons; many researchers never knew their real funder was the CIA, diffusing responsibility and obscuring oversight.

Some of the most abusive work wasn’t drugs but extreme psychological ‘treatment.’

In Montreal, psychiatrist Ewen Cameron—backed by CIA money—used massive electroshock, weeks-long sensory deprivation, chemical comas, and repetitive taped messages (“psychic driving”) on patients, often leaving them far more damaged than before.

Internal and external oversight mechanisms repeatedly failed or refused to act.

CIA Inspectors General labeled MKUltra practices “illegal and unethical” yet didn’t stop them, partly out of fear for their careers, while Congress for decades avoided real intelligence oversight, enabling a “vicious cycle” of secrecy and abuse.

Key perpetrators largely escaped accountability while victims got minimal redress.

Victims’ lawsuits in the 1980s produced depositions that underpin Lisle’s book, but cases were settled quietly for modest sums, files were illegally destroyed, and architects like Gottlieb and Helms faced no serious punishment.

WORDS WORTH SAVING

5 quotes

Some conspiracies are true, and the MKUltra stuff, they actually did this.

John Lisle

It’s just what happens with people when they have that kind of unchecked power and no oversight.

John Lisle

The capacity for humans to rationalize things… is almost limitless.

John Lisle

You have to keep secrets. But at the same time, how can I know that the secrets they’re keeping is because it’s in my interest or it’s because it’s in their interest?

John Lisle

Dread the day when the press sings nothing but the praises of those in power and Congress says there are no abuses to investigate.

John Lisle

Origins and structure of MKUltra and its OSS predecessorsSidney Gottlieb, George White, and key CIA personalitiesDrug experimentation: LSD, THC, heroin, psilocybin, and incapacitating agentsOperation Midnight Climax and unwitting civilian dosingEwen Cameron’s “psychic driving,” chemical comas, and CIA fundingOversight failures, destruction of records, and the 1970s investigationsHuman psychology: rationalization, cults, false memories, and disinformation

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