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Lewis HowesDoctor Explains Form Of PREVENTION & TREATMENT of Viruses | Roger Seheult & Lewis Howes
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EVERY SPOKEN WORD
115 min read · 22,551 words- 0:00 – 4:39
Vitamin D as a Steroid Hormone
- RSDr. Roger Seheult
We saw that people who were showing up to the hospital with COVID-19 were deficient in vitamin D
- SPSpeaker
Now, what is the, the truth about masks?
- RSDr. Roger Seheult
The problem is, is that there's two ways that the virus spreads.
- SPSpeaker
Do people need vaccines?
- RSDr. Roger Seheult
What kind of a quality of life would you like to have, is the question.
- SPSpeaker
I think you gotta have a dream. The School of Greatness. Really? [laughs] Please welcome Lewis Howes. You've been talking more about the impacts of vitamin D and how it can help prevent COVID-19 and potentially treat COVID-19. Is that what I've been learning more from your content? So are you able to share, uh, a little bit about the backstory of this discovery you've been finding and the research you've been finding and, uh, some ways we can apply this to our own life?
- RSDr. Roger Seheult
So I take care of patients in the hospital, in the ICU. Many of them recently, obviously, have COVID-19. Um, obviously it didn't used to be that way. I would just take care of regular people in the ICU, uh, and now we've just been totally flooded with, with this here in Southern California. And, uh, you know, just as a, as a, as a clinician, as a physician, I've had to look into and to try to keep up with all of the science that's coming down from, from COVID-19. I mean, a, a year ago we knew nothing about this disease, and science focused on this like a laser, and things started to come out, and what we were kinda forced to do was to look and see if we had current treatments available that might work for it, and that's how we have come to this, to this position. But the, the vitamin D, uh, interestingly, uh, Lewis, it's, it's, it's kind of funny and ironic. Uh, back in college when I was an undergrad, uh, one of the things that I did, I, is I worked in an organic chemistry research lab. I was a, a chemistry major, uh, so yeah, total nerd-
- SPSpeaker
[laughs]
- RSDr. Roger Seheult
... uh, type of thing here. But one of my jobs as an undergraduate, uh, researcher in the lab was to make vitamin D products for the graduate students to do their research on. I worked with, uh, uh, Do- Dr. Okamura, who was a biochemist, but he, he worked with, uh, um, a, a... He was a chemist, but there was a number of, of, uh, biochemists, this was at UCR, that were looking at vitamin D and its ability to bind t- to its receptor-
- SPSpeaker
Hmm
- RSDr. Roger Seheult
... and, and make all of these things. So let, let's talk a little bit about vitamin D since we started with that. I- if you just go to Google and you just Google vitamin D and the structure of vitamin D, uh, one of the things that you'll be struck with is it's a bunch of rings and circles, for those of you who don't know chemistry. But then, but then do the same thing for testosterone or estrogen or cortisol or aldosterone. These are essential, uh, steroids that the body needs to live. If, if you, uh, lose these steroid hormones, you'll, you'll die i- in, in a matter of weeks to months.
- SPSpeaker
Hmm.
- RSDr. Roger Seheult
And if you look at vitamin D, it's, it's unique that, f- to any other vitamin, vitamin B, vitamin B3, B6, uh, B12, C, none of those look like this. Vitamin D is a steroid hormone, and what that means, what we know that that means, is that vitamin D binds to its receptor and goes into the nucleus of cells, and it affects how that cell transcribes its DNA, how it makes proteins. And so that's the first thing that you oughta realize, that vitamin D is not just some cofactor that binds to something and, and allows something to happen. It actually changes the behavior of your cells.
- SPSpeaker
So without... So what does that mean? So with vitamin D, it changes the behavior of your cells, enhancing the behavior of your cells, making it healthier, stronger, uh, you know, indestructible in a sense, and with-
- RSDr. Roger Seheult
It depends. Yeah, it depends on the cell function. So sometimes the vitamin D will, uh, inhibit transcription of proteins. Sometimes it will enhance the transcription of proteins, and depending on what you want or what you need, that could have different effects.
- SPSpeaker
Vitamin D, i- uh, in general, is it good for people, or am I hearing you say that sometimes vitamin D may not be good i- in certain cases?
- RSDr. Roger Seheult
No, i- it's, uh, it's, it's good to have it when you have it, and, and in other words, sometimes you don't wanna be transcribing proteins.
- SPSpeaker
Gotcha.
- RSDr. Roger Seheult
For instance, if you're in a cytokine storm, and, uh, w- what is a cytokine storm that causes pneumonia in COVID-19? It's where you have too much cytokines. Cytokines are proteins. And where are those proteins coming from? They're coming from cells that are producing them. And so vitamin D modulates this. It's, it's the, it's the, the person with the lever that's saying, "This is what we need at this moment. This is not what we need at this moment."
- SPSpeaker
Wow, okay. So what else have you been finding in the research on, uh, vitamin D on how it actually can prevent, uh, COVID?
- 4:39 – 9:22
Evidence for Vitamin D: Meta-Analyses and Observational Studies
- RSDr. Roger Seheult
Yeah, so vitamin D is kind of like the, the cry wolf, the boy that cries wolf, because for years-
- SPSpeaker
[laughs]
- RSDr. Roger Seheult
... medicine has been looking at vitamin D and saying, "Oh, man, it's good for rickets, but it's probably good for a whole bunch of other things." And they've done studies on it, and sometimes it comes up blank, sometimes it comes up. So it's kind of like, yeah, when a lot of scientists heard that vitamin D might be beneficial in COVID-19, they said, "Yeah, fool me once, you know, shame on you. Fool me twice, shame on me," type of thing. So that's why there's been a lot of resistance-
- SPSpeaker
Hmm
- RSDr. Roger Seheult
... to saying that vitamin D is, is, is working. But if you go back to a study called, called a meta-analysis, this is where they take tons of studies and they pool it together so that the, the, the robustness of the data is huge and they can find things better. Uh, there was a study, a landmark study that was published in the British Medical Journal just a few years ago by, uh, by a scientist named Martineau, who did a meta-analysis looking at vitamin D supplementation, and he found pretty significantly that vitamin D supplementation on a regular basis, taking it either daily or weekly, decreased the incidence of acute chest infections. A- and this has been borne out multiple times. Um, there's a, uh, a- an Irish study, uh, that looked at this called Tilda, and, and they reported it recently as well. This is for acute chest infections, so generally viruses, viruses that affect the chest, so influenza, rhinovirus, probably coronavirus is in there too, all of this done before COVID-19. So we knew- From a medical standpoint, that vitamin D supplementation, especially in, in patients, you know, this was done in Northern Europe where vitamin D deficiency is quite, uh, you know, plentiful. Uh, so to see that that worked there, now let's take it and apply it to COVID-19 to see if it also works in COVID-19. Of course, the studies take a long time to do-
- SPSpeaker
Right
- RSDr. Roger Seheult
... and we didn't have those studies early on. So that's where things started.
- SPSpeaker
And what, what have the studies shown you? Uh, or are, are you doing some of these studies yourself in your labs, or are you seeing research that's being done and applying the science?
- RSDr. Roger Seheult
No. So I'm not actually doing the research, but I'm ... But, uh, you almost need somebody to, to do this type of work where you basically look across the spectrum-
- SPSpeaker
Mm
- RSDr. Roger Seheult
... see the data that's coming out, and put it together and make sense of it.
- SPSpeaker
Yeah. So what have you seen with this?
- RSDr. Roger Seheult
Yeah. So okay, so you've gotta remember, before we get started in the research, is that there are certain types of research that tell you certain things.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
There are large observational studies where you just kind of look and see what's going on, and you'll see things that are associated with each other. It doesn't tell you that one is necessarily causing the other, you just see them showing up together. And that, that sort of gives you a hypothesis, like maybe these are connected. For instance, if you, if, if you saw that a lot of people with lung cancer also carried cigarette lighters in their pocket, right? You couldn't say that the cigarette lighter is causing the cancer, but they're showing up together, so maybe there's either something else that they're both causing or caused by each other. So that's what we started seeing in the, in the first part of 2020, is observational studies. What would we see? We saw that people who were showing up to the hospital with COVID-19 were deficient in vitamin D, that people who did worse in COVID-19 were deficient in vitamin D. We started seeing that people who are older, people who have darker skin are the people that also are deficient in vitamin D, and they also have worse COVID. A- and so we started to see this, this connection, but the, but the words that go through any, any graduate of medical school or any, uh, biostatistician will tell you that cau- that association does not necessarily mean causation.
- SPSpeaker
Mm.
- RSDr. Roger Seheult
And so that's where we were for the most of 2020, until just the last few months, was these studies over and over again. Yes, we can predict how well they're gonna do based on their vitamin D levels. Yes, if they're lower, they're probably gonna have a worse course. But the part that, that we couldn't say w- based on that data was if we give vitamin D, is that gonna change something?
- SPSpeaker
Right.
- RSDr. Roger Seheult
Because maybe the disease is making the vitamin D go down and make them sick.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
And it's just like, you know, if I take a cigarette lighter out of someone's pocket, is it gonna make their lung cancer go away-
- SPSpeaker
No
- RSDr. Roger Seheult
... or prevent? Right. So that's the kind of thing. So now enter randomized controlled trials. And this is what we do. We say, "Okay, we're gonna start off, we're gonna randomize people, we're gonna blind ourselves to it, blind them to it. For one we're gonna give vitamin D, for the other we're not, and then we're gonna see what happens."
- SPSpeaker
Yeah. And so how many of these trials have been going on, and what are the findings from these, uh, these blind tests?
- 9:22 – 11:28
Randomized Trials of Vitamin D in COVID-19
- RSDr. Roger Seheult
So there's a lot of trials going on right now looking at this. There's one where they're actually gonna look at about 5,000 people. It's being conducted in Great Britain, and we don't have that data yet. The data that we do have are on a few. Let's talk about those. So there's one called the SHADE study. This was done in India on just about 100 or so people, where they gave mega doses of vitamin D in people coming into the hospital with COVID-19. 60,000 units they gave. 60-
- SPSpeaker
Is this, is it injected? Is this orally? Is this-
- RSDr. Roger Seheult
This is, this is oral, uh, oral medication. So 60,000 ... I mean, generally speaking, when you buy over the counter tablets-
- SPSpeaker
You take 5,500-
- RSDr. Roger Seheult
... or capsules
- SPSpeaker
... right? You're like ...
- RSDr. Roger Seheult
E- exactly. Exactly. So this is 60,000 units daily-
- SPSpeaker
[laughs]
- RSDr. Roger Seheult
... for seven days.
- SPSpeaker
That's a lot of vitamin D.
- RSDr. Roger Seheult
It is a lot of vitamin D. So for, for seven days they, they did this. And, uh, what they found was that the inflammatory markers in those patients were lower, and they found that as opposed to, uh, only 20% of the patients clearing the virus after, uh, three weeks, 60% of the patients cleared the virus in, in three weeks. So it, you know, it wasn't powered to look at survival and these sorts of things. Uh, they didn't notice any difference there, uh, in terms of that. But that was a study that was done. There was another study that was done in Brazil where they gave, you know, 250,000 units times one. They just gave them a whopping, I mean-
- SPSpeaker
Just a-
- RSDr. Roger Seheult
It's, it was like-
- SPSpeaker
Just a- [laughs]
- RSDr. Roger Seheult
Yeah.
- SPSpeaker
You're drinking vitamin D in supplement form.
- RSDr. Roger Seheult
E- exactly. Uh, it was, it was incredible. Uh, they didn't not, they didn't see any difference there, although they did measure that vitamin D levels went up inside-
- SPSpeaker
[laughs]
- RSDr. Roger Seheult
... so it worked. Uh, they did not notice any improvement. The, the problem there though, of course, is, uh, there was some problem with the randomization in that study where the, the intervention group, the vitamin D group, actually had, uh, sicker patients, more diabetes. Um-
- SPSpeaker
Mm
- RSDr. Roger Seheult
... and so it wasn't clear whether or not that was just a bad randomization or whether there was no effect. The one that has the most promise, a- and this is, this is the thing you gotta understand about vitamin D, is vitamin D ...
- 11:28 – 15:36
Sunlight, UVB, and How the Body Makes Vitamin D
- RSDr. Roger Seheult
Let's, so let's back up a little bit and talk about vitamin D. So people say, "Well, should I take vitamin D3, D2? What is vitamin D?" So this is how it works. You have cholesterol in your body, and it, it's, it's hanging around, and when ultraviolet B radiation comes from the sun, it comes through the epidermis, which is the top layer of your skin, and then it penetrates down into the dermis, and it, uh, comes with just enough energy to do a conformational change on one of the, uh, carbon, uh, bonds, which flips it, to be, I'm, to be kind of nerdy here, but it, it actually converts, the ultraviolet radiation converts the cholesterol structure into vitamin D.
- SPSpeaker
When you get sunlight, is there a, a certain amount of sunlight on a daily basis we should be consuming? On the skin?
- RSDr. Roger Seheult
So you typically want to... There's people that have gone into the details of this, and I can never remember, but you need about, you know, 15, 20, 30 minutes of sunlight a day. A- and since we're on the topic, there's different types of ultraviolet light. There's UVA, UVB, and UVC. So let's dispense with UVC, 'cause it doesn't have much to do with the conversation, although there is some data that UVC can kill coronavirus, but that's another topic. UVA can penetrate pretty far, and unfortunately, UVA has no role in the production of vitamin D. Uh-
- SPSpeaker
What is UVA?
- RSDr. Roger Seheult
... it's not useful. UVA is ultraviolet radiation that, that causes skin aging. It can cause cancers on your skin, uh, melanoma. So it's not something that you really wanna have, and it can, and sometimes it can actually even penetrate through glass.
- SPSpeaker
Hmm.
- RSDr. Roger Seheult
Uh, unfortunately, UVB does not penetrate glass, so sitting in front of a window with the sun coming in is not gonna help you in terms of vitamin D.
- SPSpeaker
Really?
- RSDr. Roger Seheult
You actually have to be... Yeah. You actually have to be-
- SPSpeaker
You have to be-
- RSDr. Roger Seheult
... in the sun
- SPSpeaker
... exposed with no blockage, nothing in between.
- RSDr. Roger Seheult
Absolutely, yeah. So-
- SPSpeaker
And that's UVA?
- RSDr. Roger Seheult
Uh, so UVA will not penetrate gla- sorry, will penetrate glass. UVB will not penetrate glass, and it's the UVB that we need. So, uh, if you're sitting out-
- SPSpeaker
Okay. So how do you get UVB? That's just sitting out in the sun-
- RSDr. Roger Seheult
You gotta-
- SPSpeaker
... bathing
- RSDr. Roger Seheult
... you gotta go in the sun.
- SPSpeaker
And, and what about people who say, "You know what? I don't wanna look older with my skin. I don't wanna get skin disease or cancer, so I'm gonna lather up with all this, uh, sunscreen to protect my skin." Should we use sunscreen, or is it more, you know, be in the sun for 15 minutes, then put sunscreen on?
- RSDr. Roger Seheult
Yeah, so that's exactly right. B is not gonna penetrate sunscreen very well either. So it's, it's really, it boils down to this risk-benefit.
- SPSpeaker
Hmm.
- RSDr. Roger Seheult
You know, so you've gotta look, and, and this is-
- SPSpeaker
Do I wanna look good [laughs] and, and not have wrinkles, or do I wanna-
- RSDr. Roger Seheult
Yeah
- SPSpeaker
... be healthy? [laughs]
- RSDr. Roger Seheult
So, so there are some, there are some solutions to this, right? So, uh, fish oil is rich in vitamin D. There are certain, uh, um, like mushrooms that are rich in vitamin D.
- SPSpeaker
Hmm.
- RSDr. Roger Seheult
And of course, we- look, we live in 2021, right? We've got supplementation, so you can-
- SPSpeaker
Yeah
- 15:36 – 18:34
Calcifediol Trial in Spain
- SPSpeaker
yeah.
- RSDr. Roger Seheult
Yeah, so you, so you go through, you get vitamin D, but you're still not done yet, because now the liver has to convert that into something called 25 hydroxy vitamin D. The liver takes-
- SPSpeaker
Hmm
- RSDr. Roger Seheult
... a little hydroxyl group, puts it onto the carbon, and now it's ready to be used. This is the form, by the way, that we measure when you go to the doctor and you get a blood test.
- SPSpeaker
Okay.
- RSDr. Roger Seheult
We're gonna measure the 25 hydroxy vitamin D. So all of these studies that we've talked about, uh, were measuring 25 hydroxy vitamin D levels. But the studies that we were, uh, describing, like for instance the SHaDe study and the Brazilian study, these are g- given vitamin D. So they still have to go through the liver. They still have to get hydroxylated, and that can take, uh, several days. So in this last study-
- SPSpeaker
Hmm
- RSDr. Roger Seheult
... uh, that was done in Cordona, Spain, they jumped right ahead and they supplemented these patients. They gave them, uh, pretty high doses of the 25 hydroxy vitamin D to start off with, and the results in that pilot study were pretty astounding. In the intervention group, they went from 50% of patients needing intensive care unit to just 2%, and that's a massive, uh, reduction in terms of the need for intensive care.
- SPSpeaker
So-
- RSDr. Roger Seheult
Uh, yeah
- SPSpeaker
... okay, so what did they do? When they came into, uh, the hospital, they gave them this dosage right away?
- RSDr. Roger Seheult
They gave it, they gave them a high dose, uh, of this medication called 25 hydroxy vitamin D, otherwise known as calcifediol. That's the, the, the medical name for 25 hydroxy vitamin D. They gave it to them on day one, day three, and on day seven.
- SPSpeaker
And it reduced to 2%, uh, uh, eliminating it, or what, what, what-
- RSDr. Roger Seheult
To, to, it, it went from 50% of the patients in the placebo group needing, uh, ICU to 2% of the patients in the intervention group, in the calcifediol group needing intensive care. That's a dramatic reduction.
- SPSpeaker
So intensive care meaning being on a ventilator-
- RSDr. Roger Seheult
They have to go to the-
- SPSpeaker
... being, uh, you know-
- RSDr. Roger Seheult
Exactly
- SPSpeaker
... being taken care of the whole time. So, and the others-
- RSDr. Roger Seheult
Yeah
- SPSpeaker
... two, only 2% being in there, and then what? Their symptoms went away eventually after 14 days?
- RSDr. Roger Seheult
Yeah, nobody died in the intervention group. Uh, 7.7% of those in the placebo group, uh, died. So, uh, you know, th- there was also some issues with randomization there, except in the opposite direction, that there w- seemed to be sicker people in the placebo group, so the randomization wasn't perfect. And, um-
- SPSpeaker
Mm-hmm
- RSDr. Roger Seheult
... but, but they're planning on doing a much bigger, uh, study. Uh, so we'll, we'll get some data probably here in the next few months.
- SPSpeaker
So this is a drug, or this is a supplement?
- RSDr. Roger Seheult
This is a drug. So this, you're required a prescription for this, and it's not cheap. It's actually currently used by kidney doctors to, uh, treat, uh, problems with the parathyroid gland, which is responsible for calcium in patients with kidney disease. So it's, it's not readily available, uh, but, uh, uh, it is available to, if you need to use it in the hospital, and we've been ... doing it recently, just started recently. Um, and I, so I don't have a lot of data, uh, on our patients that we're seeing, but, uh, obviously some people are getting better, some people are not.
- 18:34 – 25:16
Daily Supplement Protocol: Vitamin D, NAC, Zinc, Quercetin
- SPSpeaker
What are you recommending to people in terms of, uh, a daily prescription for natural remedies? Uh, you know, is it go out into the sun at 8:00 a.m. for 15 minutes? Is it take vitamin D supplements? Is it eat mushrooms? What, what are you suggesting to your patients?
- RSDr. Roger Seheult
So for people who have not contacted COVID-19, we actually did a video on this on MedCram. It was, uh, update 59. Uh, we recently just did, uh, the top 10 tips for, for, you know, if you actually have p- uh, positive COVID. And so what I'm recommending is based on, a lot of it's based on data in other viruses.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
Some of it's based on data in COVID-19. But we can just go down the list. Number one, vitamin D. So let's talk about vitamin D. How much should you be taking? The, you know, there's been some studies that show that if people who are at risk for vitamin D, uh, deficiency, so people who are darker color, living at higher latitudes, specifically above the 35th parallel, which is around the, the southern border of Tennessee.
- SPSpeaker
Mm.
- RSDr. Roger Seheult
If you're in California, it's kind of, uh, just south of Santa Barbara, that area, um, then taking, uh, vitamin D supplemation- supplementation is a good idea. So how much is too much? We actually-
- SPSpeaker
[laughs]
- RSDr. Roger Seheult
... probably overestimate the toxicity of vitamin D. It's, it's probably one of the safest fat-soluble vitamins. That being said, it's not completely risk-free, but the society, uh, endocrinology society says this. They say that what, what is the maximum dose that you can take without supervision from a physician, and, uh, for someone who is at risk for vitamin D deficiency? The answer is 4,000 international units daily.
- SPSpeaker
4,000 daily?
- RSDr. Roger Seheult
Yeah.
- SPSpeaker
Okay.
- RSDr. Roger Seheult
And, and, and so what would I do if someone asked me, uh, you know, I take 5,000 international units daily just because I had my levels checked.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
Uh, I think the, the right answer is, if you can, get your levels checked.
- SPSpeaker
Got it.
- RSDr. Roger Seheult
And where would you wanna be? It's measured in nanograms per milliliter. Uh, I would say based on the data that we've seen, the retrospective data in the United States, we see that there is an increase in SARS-CoV-2 positivity once you start going below 50 nanograms per milliliter.
- SPSpeaker
Hmm. Okay.
- RSDr. Roger Seheult
So if you're, if, if you're not above 50, you might wanna bump it up at least over the winter season. And, and, and wouldn't you know it, uh, [laughs] that what are we seeing? We're seeing a rebound in SARS-CoV-2, uh, in the winter season.
- SPSpeaker
Hmm.
- RSDr. Roger Seheult
So this, you know, this is not, it's not rocket science. It's because we're not getting enough sunlight. The days are short. People don't have enough vitamin D. A- and so this is what, what the theory is.
- SPSpeaker
Okay.
- RSDr. Roger Seheult
So that's vitamin D.
- SPSpeaker
Number three?
- RSDr. Roger Seheult
Uh, so the other thing that, that I would talk about is, uh, NAC. That's one of the things that we've been talking about. NAC is N-acetylcysteine. There is, uh, there's some qu- pretty good data that shows that SARS-CoV-2, when it infects your cell, it knocks out the receptor called the ACE2 receptor. This ACE2 receptor is very important in regulating oxidative stress in your body. Uh, we could talk for an hour about oxidative stress and hydroxy radicals and, and things that, that are very high in people who get COVID-19. So diabetes, obesity, oxidative stress is very high, so you get this viral hit, and it tips you over the edge. So one of the things that may be beneficial is consuming products that are antioxidants.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
So, you know, berries, strawberries, raspberries, elderberries, blackberries, all of those are excellent things to do. But if you want to increase even more, then taking 600 milligrams of NAC twice daily was shown in a previous study to reduce the symptoms of the flu, uh, virus in a winter season when it was done prospectively. So in other words, they randomized people to placebo versus 600 milligrams of NAC twice daily, and they did not see a difference in the incidence of the flu in those people, but they did notice a significant reduction in the severity-
- SPSpeaker
Hmm
- RSDr. Roger Seheult
... of the illness that the people suffered when they were on NAC.
- SPSpeaker
So instead of being-
- RSDr. Roger Seheult
So I don't have data
- 25:16 – 30:44
Contrast Showers and the Innate Immune System
- RSDr. Roger Seheult
Yes. A- a- and then the last thing, I left, I left the last thing for, uh, for the end, and that's something that you're probably like, "Well, what are you doing with this?" And it's a l- it's a long story that we can break into, but, uh, contrast showers.
- SPSpeaker
Oh, yes. You're speaking my language.
- RSDr. Roger Seheult
Yeah.
- SPSpeaker
You're speaking my... So hot and cold, or-
- RSDr. Roger Seheult
Correct
- SPSpeaker
... cold only?
- RSDr. Roger Seheult
I do hot for five minutes-
- SPSpeaker
Mm
- RSDr. Roger Seheult
... and then I do cold for one minute, and then I do five for hot again, and then one for cold, and then finish it up with three for hot and one for cold. And, and the one that, that clued me on to that, uh, formula was, uh, a Dr. Neil Nedley, who is out of, uh, Weimar, California, who, who's actually done a lot of, uh, research and, and actually has a, uh, a clinic up there, uh, called Newstart that's, that's doing this sort of stuff and, and with amazing results.
- SPSpeaker
So what is... So this isn't clinically tested yet, but you're, you feel like this-
- RSDr. Roger Seheult
Well, let me, let me tell you the story.
- SPSpeaker
Yeah, tell me the story.
- RSDr. Roger Seheult
It's, it's, it's a long story, but, uh-
- SPSpeaker
Bec- because, 'cause we've had, uh, you know, Wim Hof on, who is a-
- RSDr. Roger Seheult
Yes
- SPSpeaker
... proponent of this and, and the power of boosting immunity and how-
- RSDr. Roger Seheult
Yeah
- SPSpeaker
... he's done these kind of superhuman tests where they have injected him with, uh, you know, viruses, and he's been able to essentially say, "No, go away from my body," [laughs] in the cold and through breathing and mindset. So, uh-
- RSDr. Roger Seheult
Yeah
- SPSpeaker
... yeah, I'd love to hear your story on this.
- RSDr. Roger Seheult
[clears throat] So you don't need to, to be w- [laughs] You don't need to be Hof to do that.
- SPSpeaker
[laughs]
- RSDr. Roger Seheult
You don't need to be, uh, you know, part of the Polar Bear Club. Uh, not to say that there isn't some use for that. So I, I, I started to look into the research on this, and one of the areas that really held my fascination was the 1919 pandemic.
- SPSpeaker
Mm.
- RSDr. Roger Seheult
1918, uh, flu pandemic and what happened. So, so one of the things that you've got to understand about COVID is the timing. Timing is everything, and really there are two phases to this disease, and you can really draw the line, uh, with COVID is when someone is at home versus when someone is at the hospital. COVID and what's going on with COVID at home is completely a different animal than what's going on in the hospital-
- SPSpeaker
Mm
- RSDr. Roger Seheult
... and I'll explain. Uh, and this has been borne out by research and studies, and, and I think this is, this is not controversial, this is pretty well understood, is that when somebody's infected with SARS-CoV-2, it suppresses the innate immune system. Now, the innate immune system is part of your immune system that gives you a fever. It sends out these macrophages to, to kill, uh, things that don't look like, uh, what it's supposed to look like, as opposed to the adaptive immune system, which is later on. That's antibodies. That's protein structures. That's T cells, B cells. So what the virus does is it, it, it has this strategy where it infects the person, it suppresses the immune system, and allows it to replicate and spread into multiple organs of your body. And then when the adaptive immune system comes on, it now has all of these cells that it has to attack. All of that inflammation, especially in the lung, can put you into pneumonia-
- SPSpeaker
Mm
- RSDr. Roger Seheult
... gets you hospitalized and on, on a ventilator. And so the, the, the, the strategy should be at the beginning of the virus is to im- improve, is to substantiate, is to boost the innate immune system to get rid of the virus before it gets to that phase. But what we're noticing is when people get to the hospital and they have pneumonia, is the, the immune system is overamped. It's causing, uh, inflammation too much, and that's why things like steroids work.
- SPSpeaker
Mm.
- 30:44 – 41:26
1918 Pandemic: Sanitariums vs. Army Camps and Fomentations
- RSDr. Roger Seheult
So what was it back in, prior to 1928? What was it that we did in, in these hospitals, uh, when the flu pandemic arrived? Uh, and so I started to research that, and what I found was something that was really interesting and started to really attract my attention and start to look into it. If you go back, there was, uh, a h- there was a number of hospitals, especially in the northeastern part of the United States, which is where, you know, America basically was, was centered at that time, that was... There was this rebirth, if you, if you will, uh, among the snake oil experts and, and the people peddling, uh, you know, uh, morphine and arsenic for all of these things that could work. There was this understanding or this rebirth in the late 1800s about natural remedies and about- Mm-hmm ... things, you know, uh, in terms of, of nature and of fresh air, sunlight, these sorts of things. And these hospitals, they were known as, as sanitariums. Well, there was, uh, one particular fellow, actually a number of them. There was a Dr. Jackson in New York, but more, uh, notably, uh, John Harvey Kellogg, who you may recognize that name as, as starting Kellogg's Corn Flakes and, and this health food industry back at that time. He was the, the director of the Battle Creek Sanitarium in Michigan, which was the world's largest hospital, and they saw very, very, uh, you know, elite patients. People like, uh, you know, J.C. Penney, people like Montgomery Ward- Mm ... people like Franklin Delano Roosevelt- Wow ... Amelia Earhart. They would all go to this hospital for the- They were like the Cleveland Clinic of their time ... for this... Exactly. Yeah. Exactly. And, and these weren't just, like, things that they were pulling out of a hat. These things worked, and that's why people went there, because it was the state of the art. So what did they do? They were using hydrothermal therapy. They were heating up the pa- I mean, if you can see pictures of this, it's- Mm-hmm ... it's, it's a hilarious crack-up because you'll look down the hospital hallway and you'll see these rooms, these treatment rooms with little holes, and out of these little holes were their heads. The patients' heads were popping out, and this room was used to heat up the body- It was a hot box ... to simulate a- It was a sauna. Exactly. Yeah. Exactly. Yeah. That's exactly what they were doing, and keeping their head cool. Mm-hmm. Now, this, this, uh, this tar- type of treatment spread and, and it was, it was well understood, and I, I think the zenith of this- Mm ... interestingly, was a guy by the name of, um, uh, Wagner Jauregg. He was an Austrian psychiatrist, and he had, uh, his insane asylum there in Austria and, and there was obviously a, a lot of people with, uh, neurosyphilis. Neurosyphilis is a condition, obviously, where you have syphilis that goes to the brain. It's, it's a, it's a type of bacteria. Uh, it's an organism. And this is before penicillin, so how... We, we couldn't treat it. We could treat malaria, but we couldn't treat it. So, so this guy, Jaure- Jauregg, uh, Wagner Jauregg, noticed that when his neurosyphilis patients had fevers, they actually responded and they, they got better. Their symptoms abated. Mm. And so he had this idea: What would happen if I purposefully infected them with malaria? [laughs] Right. 'Cause malaria gives you really high fevers. And so he did it, and wouldn't you know it, he cured them of their neurosyphilis- No way ... and then he treated them. Yeah. And then he treated them with, uh... He treated them with the known treatment at the time for malaria. Cleared the malaria. So he was able to basically cure neurosyphilis by inducing a fever. [laughs] And for this, he, he actually won the Nobel Prize in Medicine, ironically, in 1927, the year before penicillin was discovered. So if you look at the 30,000-foot level about where we've come in the United States, and in fact, the world, in the last hundred years, we were going down a path of enhancing the body's own way of dealing with the virus- Mm-hmm ... or whatever bacteria, whatever it was. You know, the immune system is so incredibly complex. We didn't understand it at the time, but we understand it now, and it has so many ways, so many angles of attacking pathogens- Mm-hmm ... that if we are able to just turn on that machine, that machine is gonna be... I mean, let's look at it. People who get infected with coronavirus today, more than 80% of them recover on their own because of the immune system. It's only a, a, a small amount of people that cannot, cannot deal with the infection and, and they end up in the hospital. Of course, we have so many people being infected that it's overwhelming our system. So what happened in 1928 was the discovery of penicillin, the discovery of all these medications, randomized control trials, the fe- the, the, the FDA, that what we've done is we've... Since that time, we've gone down a road where we, we take a chronic disease, we f- we study it, we know, and we, we do the randomized trials, which is what we should do, and we come up with treatments that treat that. And that works really well until you have a pandemic. [laughs] And now you have a, a, a brand-new disease that comes on, on, on the scene. It is overwhelming everybody. We don't... There's no way we can do the randomized control trials fast enough. And so what I became interested in is, is there something that we can do that isn't a pill, that i- that doesn't need to be prescribed, that doesn't need to have a factory to make, that we can do to already enhance a system that we are already given when we're born to help deal with the disease that's already kinda dealing with it anyway? But if we could just go from 80% to 85, 80 to 90%, that would take care of it. That would have a tremendous impact on, on taking off the stress from our, our healthcare system. So that's what I intended to do. So I looked at what were these guys doing at the time of the pandemic? Because here these people are. They know what to do with these diseases. This is the treatments that they're using. What did they do during the pandemic to treat this? And wouldn't you know it, I found- ... the resource, and it was amazing. And, and, uh, I'll stop there to see if there's [laughs] any questions before I go on, because the next part was just mind-blowing.
- SPSpeaker
Yeah, what's the re- what's the resource or what's the research-
- RSDr. Roger Seheult
Okay
- SPSpeaker
... on this?
- RSDr. Roger Seheult
Okay. So there was this guy b- by the name of Dr. Ruble. Dr. Ruble was the medical director of the, of the sanitarium in Boston. It was the New England Sanitarium, and he said, this is what he said. He said, uh, basically I'm paraphrasing. He, he wrote this article in a ... It wasn't even a scientific journal. It was a, a, it was a church periodical.
- SPSpeaker
Hmm.
- RSDr. Roger Seheult
Um, these were all, these were all Seventh Day Adventist institutions in the northeastern part of the United States that were doing hydrotherapy. Same thing with the Battle Creek Sanitarium. And what he wrote in there is like, "The pandemic has offered us this opportunity to really put to the test these type of treatments that we're doing. Let's see if it works." So this is what he did. He coupled, he, he got all of the information from about s- 10 sanitariums in the northeast of the United States, and he pooled the data. And then he went to the Army camps, 'cause in the Army camps they had the best, they had the brightest doctors. They had all of the resources. A- as you remem- remember from, uh, 1918, these people from Europe, these soldiers were coming back to the United States. The war had just ended, and they were bringing back unfortunately with them the, the flu.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
And so as they came back, they made these camps in the United States and they were treating these people. So about 20% of the people in the camps came down with the flu, and when they came down with the flu, again, two components to the disease. The first part was the virus, the, the viral replication phase, and then pneumonia. And if they got pneumonia, there's no antibiotics. It was about, it was a d- it was almost like a death sentence, 'cause it was about 40 to 50% mortality rate, okay?
- SPSpeaker
Wow.
- RSDr. Roger Seheult
So the key was is you don't want them to get to the pneumonia stage. You wanna get this before it gets to the pneumonia stage. And the, the thinking, the, the thinking in the Army camps at the time was what's killing these people? It must be the fever. It must be the symptoms of the flu. And so aspirin had just come out in 1899, Bayer aspirin. Ironically it was a German company that came up with aspirin.
- SPSpeaker
Hmm.
- RSDr. Roger Seheult
And so they were giving aspirin to all of these people in the camps. I mean, 'cause aspirin would take away the fever. Aspirin ... Ironically the fever is the sign that the innate immune system is doing something, right? You get interferon, fever goes up. And so the very thing that was trying to help these patients, they were getting rid of-
- SPSpeaker
They were, they were suppressing it-
- RSDr. Roger Seheult
Was-
- SPSpeaker
... which was causing-
- RSDr. Roger Seheult
Exactly
- SPSpeaker
... them to be more sick.
- RSDr. Roger Seheult
Exactly. And so a- at the end of the day, it was about 10, 15% of these patients were coming down with pneumonia, okay? Because they were giving aspirin and all of these sorts of things. Compare that now to what was going on in the sanitariums. So in the sanitariums they were not doing this. What they were doing, what was the treatment? What was the rational treatment in the words of Dr. Ruble that they were doing? So as soon as they came down with symptoms, they would isolate them. They would put them in bed. They would have them rest. Uh, they would also expose them several times a day to sunlight, sunshine, fresh air. Ventilation was very important. And then they would do something called fomentations, and that's the old term for hydrotherapy. Essentially what they would do practically speaking is they would get a pot of boiling water. They would put these towels into the pot of boiling water, take it out, wring it out, and they would place it on the bed. They, the patient would lie on this with a, a sheet in between so they wouldn't be burned, and then they would place fomentations on top of them, basically creating, if you will, a, a hot box. And they would do this for about 20 minutes. When they were done, they would then put cold water on them and rub it, and so basically to cause vasoconstriction we now understand-
- SPSpeaker
Hmm
- RSDr. Roger Seheult
... and lock that heat in. So only about 2 to 3% of those patients came down with pneumonia. So at the end of the day, the overall case infectivity, uh, mortality rate was like 6% for the, uh, Army camps, and 1% for, uh, these, these hospitals, uh, these sanitariums. So then I looked at that. I, I said, "That, that is remarkable."
- SPSpeaker
Yeah. [laughs]
- RSDr. Roger Seheult
That here we have ... It's not a randomized control trial. Different populations, different things, but it at least tells me that this has been tried before. I mean, a Nobel Prize has been given on the basis of, of this type of treatment. And, and here's something that you don't need a prescription for. You don't need a test. If you feel bad, you can start this right away. And, and so as one of my recommendations, going back-
- SPSpeaker
Hmm
- RSDr. Roger Seheult
... to the ori- original question, doing contrast showers is a nice way of, of doing this as a tonic to help prevent and keep your, uh, immune system on kind of a sentinel mode, looking around. But if you actually come down with it, if I've, if I've gotten where I think I might be coming down with something, I will, I will do the hot fomentations, and you'll just be sweating there. But after you're done, it's, it's ... You, you feel amazing.
- SPSpeaker
Really?
- RSDr. Roger Seheult
Yeah.
- 41:26 – 50:40
Practicing Hydrotherapy at Home and the Finnish Sauna Example
- SPSpeaker
So if you feel like, "Okay, I'm getting a cold, I'm getting a flu, I'm getting a virus," whatever, something, what would you do from that moment as you started to feel that? You go right into hot/cold showers? Is it the, the-
- RSDr. Roger Seheult
So first thing I would do is I would alert my wife. [laughs]
- SPSpeaker
Yeah, of course.
- RSDr. Roger Seheult
'Cause it's hard to do it on yourself.
- SPSpeaker
Yeah.
- RSDr. Roger Seheult
And, and what she'll do is she'll get a, a, a, a large foot bath, and she'll put the hottest water you can tolerate in there and put that on the ground. I'll-
- SPSpeaker
Just for your feet?
- RSDr. Roger Seheult
... I'll lay down. Yep, and I'll put my feet in there. Um, and that, that helps. A- anything that, any part of your body that you can do to try to heat it up, heat up your core body temperature is important.
- SPSpeaker
Okay.
- RSDr. Roger Seheult
So, so basically we- we'll put down a hot towel. I'll lay on that, keep my feet in there. Anything that, that will increase your core body temperature.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
Cover me up with a, a, a blanket. So I'll be basically in a h- [laughs] in my own hot box. I'll have a, a, a cold towel on my head, cold towel across my carotid arteries here so that my head remains cool and it doesn't know that my body's being heated-
- SPSpeaker
Huh
- RSDr. Roger Seheult
... but I'm being heated up. And, uh, and then that's for about 20 minutes, and then that comes off. I get cold water on the feet, cold water on, on my chest, uh, and then, uh, for just a brief moment for about 30 seconds, and then I go lay down. And, uh, you can do that once, twice a day. And what that will do, a- a- and there's, this is not hocus pocus.
- SPSpeaker
[laughs]
- RSDr. Roger Seheult
They've actually, they have actually done the studies where they, they will take monocytes, which are responsible for secreting interferon, take monocytes out of ... They've done the study where they take them out of people at different temperatures, and then they expose them to, uh, you know, a bacterial challenge or some, some sort of, uh, foreign challenge. And right when you get to about 39 degrees- The interferon response goes up tenfold. I mean, it starts to go up, starts to go up, and then right about 39 degrees centigrade, which is, uh, you know, maybe 102 degrees Fahrenheit, uh, you get a tenfold increase in interferon response, which is exactly the same substance that we are lacking early on in the course of this disease, COVID-19.
- SPSpeaker
Is this something that someone could prevent on a weekly basis where they do hot-cold as well, or is this just something you do in the shower? It's like, "Okay, let me do hot-cold for five minutes and, and help me there."
- RSDr. Roger Seheult
I, so I, I do my showers hot-cold, but, um, that's another point that you bring up, because there is a whole society-
- SPSpeaker
[laughs]
- RSDr. Roger Seheult
... on this planet that does literally this pretty much twice a week, five times a week, and y- you know who I'm talking about.
- SPSpeaker
Yeah, and they don't get sick.
- RSDr. Roger Seheult
Yeah.
- SPSpeaker
Or they, they, they say that, you know, I talked to Wim Hof and he's like, "I don't remember the last time I got sick." And, uh-
- RSDr. Roger Seheult
Yeah, I mean, I mean, there's, uh, the Fins.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
That there are so many saunas in Finland that if you were to ask every Finnish person to go into a sauna at the same time, there would be enough saunas to do that.
- SPSpeaker
[laughs] Yeah. And then they jump in the cold. They jump in-
- RSDr. Roger Seheult
Exactly
- SPSpeaker
... the cold water.
- RSDr. Roger Seheult
And, and so if you look at the, the COVID data in Finland, uh, they, they outperform just about any other Nordic country-
- 50:40 – 57:40
Politics, Masks, Ventilation and Airplanes
- SPSpeaker
Now, what is the, the truth about, uh, masks in your opinion? Or I guess based on the data.
- RSDr. Roger Seheult
Yeah, so basically the pro- here's the problem. The problem is, is that there's two ways that the virus spreads. A- a- and here are the two ways. It can spread in large droplets. So if I'm standing in front of you and I speak, and, you know, spittle comes out of my mouth and lands on you, uh, in that droplet are probably hundreds of thousands if not millions of particles of the virus, and, and that's a large amount. And if, if you, you know, if that goes into your mouth, or you wipe, or you touch, you're gonna get the virus. So what masks do is that they avoid, they, they completely eliminate that. That's why the masks don't have to be, uh, to the level of being airborne. They don't have to filter out viral particles. They just have to eliminate droplets.
- SPSpeaker
Mm.
- RSDr. Roger Seheult
But unfortunately, that's not the only way that it spreads.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
So if you can imagine, uh, it, being in a room and somebody's smoking on the, on the other side of that room, even if they're wearing a mask and you're wearing a mask, you're gonna eventually smell the smoke. Because the, the very tiny little particles of smoke are going to fill up that room eventually because of diffusion. That's another way, an airborne way. That's another way that the virus spreads, and masks aren't gonna help that. That's why you can go, you... If everybody went to a large meeting and everyone wore masks and it was an enclosed room with no ventilation, uh, COVID's gonna spread like wildfire.
- SPSpeaker
Mm.
- RSDr. Roger Seheult
And, and that's why we, we get these different... They say like, "Look, look here, the masks didn't help. Why are they making us wear a mask?" It's 'cause there's two different ways. And so the way you take care of that way of the virus spreading is through ventilation. And really, unfortunately, the CDC hasn't gotten onto this until just recently. There's a guy that we had on, um, a researcher from the Harvard School of Public Health, Dr. Joseph Allen, who's been really on this since the very beginning, talking about ventilation, talking about cracking your windows open, talking about if you're in a room, making sure that there's enough turnover of air in the room.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
And so really, you gotta do both of those. A- and so it, you know, a- and people don't understand that. Unfortunately, politicians don't understand that. You know, uh, here we, we have outdoor dining shutting down. So, so why is that? We don't want people congregating. But it's outdoors, and so the chances of you getting a virus outdoors in well-ventilated areas is pretty low. So what do people do? Instead of having their parties at outside dining, they go home and they have big parties inside of a house. And, and what happens is we get, you know, a lot of people, uh, coming down with the virus.
- SPSpeaker
I'm surprised more. So-
- RSDr. Roger Seheult
Yeah
- SPSpeaker
... 'cause I've been hearing, uh, that people are s- well, wearing the mask all day long, they're still getting it, certain people, right?
- RSDr. Roger Seheult
Yeah.
- SPSpeaker
So it's not, it's not only the m- the mask pro- helps, but it's not, you can still can s- get the virus.
- RSDr. Roger Seheult
Well, well, and here's the, here's the case in point. So imagine getting a bunch of people all wearing masks into a long cylinder and keeping them in there for hours on end.
- SPSpeaker
Are you, are you talking about when we go on a plane? [laughs]
- RSDr. Roger Seheult
Exactly. A- and we haven't r- I mean, there's been some stories, but for the, for the by and large, we haven't had massive outbreaks of, of COVID-19 coming from planes.
- SPSpeaker
Why is that?
- RSDr. Roger Seheult
And why is that? Here it is, is because that air is highly filtered through HEPA filters. 50% of the air coming out of those jets from up above, 50% of that air comes from outside, which ostensibly I would hope has no viral particles, and the other half is coming recirculating from the plane, but it's gone through extensive HEPA filtration-
- SPSpeaker
Mm
- RSDr. Roger Seheult
... where it completely takes out the virus. And so that is probably the cleanest place that you can possibly be-
- SPSpeaker
Really? [laughs]
- RSDr. Roger Seheult
... is on a plane. Absolutely. And the problem with it-
- SPSpeaker
Even if someone's sitting next to you-
- RSDr. Roger Seheult
Well-
- SPSpeaker
... like, one foot away-
- RSDr. Roger Seheult
If they're sitting-
- SPSpeaker
... and they cough
- RSDr. Roger Seheult
... if they're sitting...
- 57:40 – 1:06:27
Comorbidities, Diet, and Compassionate Lifestyle Change
- SPSpeaker
I'm curious about this comorbidities, uh, idea.
- RSDr. Roger Seheult
Yeah.
- SPSpeaker
What do you think, or what is the research proving and showing is one of the main comorbidities when someone has this, whether it's obesity or diabetes or something else, is also impacting it at a high level? That if they decreased that thing, they should have a greater chance of defending themselves and having a stronger immune system for-
- RSDr. Roger Seheult
Yeah
- SPSpeaker
... not getting COVID?
- RSDr. Roger Seheult
It, it's the chicken and the egg-
- SPSpeaker
Mm-hmm
- RSDr. Roger Seheult
... unfortunately, because we see that stress, oxidative stress causes obesity, and then obesity causes oxidative stress. A- and then, uh, when you have a lot of fat, you store a lot of fat-soluble things and make it not available, so, like, vitamin D is a fat-soluble vitamin. So, so it's hard to tease out exactly what it is, but we do know this. Here are the comorbid things. Here are the things that, that, that make people more susceptible to dying from COVID-19. Kidney disease.
- SPSpeaker
Hmm.
- RSDr. Roger Seheult
Kidney disease is, is, is a big thing. Number two, diabetes. Uh, and so those are, are very big things. So why, why would that be? When you get infected with the virus, the virus is binding to this protein called ACE2, okay? ACE2 is part of a huge, complex system of, of enzymes that regulate your oxidative stress. And so imagine you are, imagine that you are obese, imagine that you have kidney disease, diabetes. Your body is literally sitting on the edge of a cliff. Not literally, figuratively sitting on the edge of a cliff.
- SPSpeaker
[laughs] Right, right.
- RSDr. Roger Seheult
Okay? All right? And, and it's basically getting by. It's getting by. You're, you're not in any kind of... I mean, it's, it's compensating for the system. Now imagine that you completely remove this, this enzyme. By the way, ACE2 is responsible for cutting down on oxidative stress and increasing proteins that, uh, cause reduction, uh, antioxidants, essentially. So now you basically pull the mat from under the whole thing. You tip it over the edge, and you can see very clearly how, uh, this type of a hit cannot be compensated for.
- SPSpeaker
Hmm.
- RSDr. Roger Seheult
It's, it's... I mean, there's so many different analogies I can use, but the virus basically causes everything to start unraveling, and once things start to unravel, uh, things become compounded and you reach that point of no return. And unfortunately for some of the patients, by the time they reach the hospital, we have already reached the point of no return in a lot of those cases.
- SPSpeaker
No return meaning death.
- RSDr. Roger Seheult
Yeah.
- SPSpeaker
And kidney disease and diabetes are two major factors that will increase the likeness of this. Is that right?
- RSDr. Roger Seheult
Absolutely.
- SPSpeaker
And how do we, [laughs] how do we prevent diabetes and kidneys disease?
- RSDr. Roger Seheult
Well, I, I think a lot of it has to do with diet and activity.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
Um, these are things that we as a culture, as a society, have placed more emphasis on commercialism, advertising, taste, uh, short-term benefits, and not really the long-term benefits. It's kind of like we've been, uh, in class, and we've been, uh, you know, cramming for quizzes all along, and now we're sitting down for the final exam, and, and we got nothing.
- SPSpeaker
That was my whole life in school. [laughs]
- RSDr. Roger Seheult
[laughs]
- SPSpeaker
Okay.
- RSDr. Roger Seheult
Yeah, I mean, it... Yeah. I, I, I mean, I could talk to you about so many different things. We, we know, for instance, that high-fructose corn syrup is a big inhibitor of vitamin D. We know that. We, we know that, uh, the scientists-
- SPSpeaker
Hmm
- RSDr. Roger Seheult
... when they-
- SPSpeaker
Really?
- RSDr. Roger Seheult
... when they induce... Yeah. When they induce oxidative stress models in their, in their mice, how do they do that? By feeding them high-fructose corn syrup. Um, there's one country on this planet that consumes more high fructose corn syrup than any other country. In fact, number two is less than half of that consumption.
- 1:06:27 – 1:14:56
Exercise, Depression, Anxiety and the J-Curve
- SPSpeaker
How does depression and anxiety play in with weakening your immune system and attracting more-
- RSDr. Roger Seheult
Oh
- SPSpeaker
... coronavirus?
- RSDr. Roger Seheult
A- a- and this is not... I'll have to be honest with you. This is not something that I was an expert in until recently. I'm not even an expert in it now. I'm just starting to learn about it. I, I'm not a psychiatrist. I'm not a neurologist. But I can tell you that depression and anxiety are, are two things that rev each other up. Anxiety causes depression, and, uh, anxiety is something that you get when, when we're in this pandemic. We've been in this pandemic for about a year now.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
And, uh, people are very anxious. They're anxious about getting COVID-19. There's just a recent article that came out that showed that children, a recent study in children, uh, that have had distance learning and, and these sorts of things that, that anxiety is becoming more and more, uh, prevalent, uh, suicides, et cetera. And, and what we f- what I found, there was a interesting, uh, research article that was published by Dr. Jennifer Heisz out of the, uh, the FIT Lab in McMaster University in Ontario that I thought was excellent work. She looked at a ran- she did a randomized control trial, and she took students right before exams. So you remember what it was like before exams, right?
- SPSpeaker
It was stressful.
- RSDr. Roger Seheult
Six weeks be- yeah
- SPSpeaker
[laughs]
- RSDr. Roger Seheult
Six weeks before exams. They, they looked at them for six weeks, and all of these students were gonna go through exams. Very stressful time in their life. Their, their careers are dependent on this. Uh, this was before COVID. And, and they randomized them to three different tracks. Number one, do nothing. Just keep doing what you're doing. That was the control group. Number two was a low-intensity, uh, exercise regimen. So they did three times a week.
- SPSpeaker
Meaning, uh-
- RSDr. Roger Seheult
So they did-
- SPSpeaker
... a walk, a jog, a hike, or...?
- RSDr. Roger Seheult
In this case, they were very specific. They, they had to do it, uh, very scientifically, so they actually did a VO2 max test, which is... If you don't know what that is-
- SPSpeaker
Yeah
- RSDr. Roger Seheult
... it's where they put a thing in your mouth, you pedal, and they measure. So th- they, they made it a very specific percentage of their total max. It turned out to be, you know, getting their heart rate up to about 140, uh-
- SPSpeaker
Mm-hmm
- RSDr. Roger Seheult
... beats per minute for about-
- SPSpeaker
Sure
- RSDr. Roger Seheult
... 20 minutes. Um, and they did it three times a week.
- SPSpeaker
Okay.
- RSDr. Roger Seheult
And they did it for six weeks, so 18 treatments, okay?
- SPSpeaker
And the third group?
- RSDr. Roger Seheult
And then the third, the third group was this high-intensity group. So heart rate was, like, 180 beats per minute, okay? Really high-intensity, uh, exercise, again, three times a week for, for six weeks. And what did they measure? They measured cytokines. Uh, so these inflammatory cytokines like IL-6, which has been implicated in, in COVID-19. They looked at depression scores, uh, so validated depression scores, not just, you know... And, and they blinded the, the, the researchers to which students were getting what. I don't know how they did it, but that, that's what they did. So they looked at, at, at blood tests. They looked at depression scores. They looked at a whole host of things. What did they find? This is what they found. They found... First, first thing they found that was amazing was in the control group, in the control group, that depression scores at the beginning versus at the end of the six weeks, which ended just at the same time as finals, depression scores went up dramatically. So first thing that they found was, number one, it doesn't take a long time of stress exposure to increase your risk of depression. That was six weeks. We're, we're in it for a full year.
- SPSpeaker
So six-
- RSDr. Roger Seheult
Right?
- SPSpeaker
So six weeks in the control group, the depression went up across the board of all three groups?
- RSDr. Roger Seheult
No, just in the control group.
- SPSpeaker
The control group meaning the one that didn't do anything.
- RSDr. Roger Seheult
Didn't do any exercise.
- 1:14:56 – 1:22:12
Understanding the COVID Vaccine: Risk, Benefit and mRNA
- SPSpeaker
Now, can you explain more about the vaccine? And y- this is, again, gonna be controversial on different sides. We have people that are science-based and love the science, and then we have a certain part of the population that is 100% against vaccines. We've had this conversation with doctors in the past-
- RSDr. Roger Seheult
Yeah
- SPSpeaker
... uh, who, you know, I'll, I'll put out information about this, and people, you know, went unfollow and, and unsubscribe from everything that I've ever done.
- RSDr. Roger Seheult
[laughs]
- SPSpeaker
Uh, so based on scientific evidence and what we-
- RSDr. Roger Seheult
Yeah
- SPSpeaker
... know so far with this new vaccine that's out there, what is in the vaccine? Sh- you know, what is your recommendation? And if people don't wanna get the vaccine, do you feel like that's okay as well?
- RSDr. Roger Seheult
Good question. So the vaccine is, is like this big umbrella, and we- we'll have to talk... I'll probably limit my talk to just the ones that are available, because there are-
- SPSpeaker
Yeah
- RSDr. Roger Seheult
... gonna be so many different types made using different techniques and, and how they, how they work. The question... Well, first of all, the first thing that you have to understand is that nothing in life is without risk. Everything has risk, and the decisions that we make, uh, as medical doctors, as, as providers is, is what I'm about to do gonna have more risk than benefit or more benefit than risk? And that determines what we do. When you go to the supermarket, uh, you could get in a head-on collision. You could get... Y- you know, y- all of these sorts of things could happen, but you, in your mind, make a mental calculation that getting food from the supermarket has a better benefit than the risk of you getting in a head-on collision, so you do it, okay?
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
So in other words, if we find that there are risks with something, it doesn't necessarily mean that we don't do it. We do things all the time in the hospital to patients that have risk, but we believe that we are correct in doing it because the, the benefit we're gonna derive is greater than that risk. Sometimes we're right, sometimes we're wrong, but if we do it hundreds of times, sometimes you're gonna have problems, sometimes you're not. Okay, so that's the first thing. Second thing is, uh, w- the decision to get vaccinated in a pandemic is not a decision to get vaccinated versus nothing. It's to get vaccinated versus getting the infection. That's, that's the decision that you have to make. And so when you look at the risks of getting vaccinated, for instance, what is the long-term effects of getting the vaccine? We don't really know the long-term effects because it hasn't been a long time-
- SPSpeaker
Right
- RSDr. Roger Seheult
... since we've gotten the vaccine. But if you look at other vaccines that we've done in the past, we can see that most of the long-term effects that have occurred on those vaccines usually pop up within the first two to three months, and so we can kinda get a sense about what the long-term side effects are gonna be. Now, let's look at the virus. We don't know the long-term implications of being infected with coronavirus.
- SPSpeaker
Mm.
- RSDr. Roger Seheult
Do people get diseases after viruses? Absolutely. Can people get post-viral, uh, uh, complications? Absolutely. People can get myocarditis, Guillain-Barre. These, this is a condition where you basically, you can't move, uh, a- and, and you need to go on a ventilator just by getting the infection. Uh, there's a recent study that showed that over half of normal asymptomatic athletes still had signs of myocarditis, that's inflammation of the heart tissue, after, uh, either a mild or asymptomatic bout of COVID-19. Okay? So i- i- you c- you've gotta do this understanding really what your choices are. In both cases, the vaccine and the virus, what happens is a particle infects one of your cells, it releases an messenger RNA, which is an information packet that tells your cell what kind of protein to make. In the case of the virus, the, the ribosome, which is part of the cell, is gonna make more viral particles, and those viral particles are gonna spread to other cells and make more viral particles, and that's exactly what's happening in the first phase of, uh, uh, of COVID-19. In the, in the, uh, case of the vaccine, the vaccine is much more attenuated. It's just a little component, a little information packet on just the protein. It's just making a little portion of the protein, the spike protein. And so your cell, when this information packet goes in, the cell is going to make a lot of these proteins and put them on the surface-
- SPSpeaker
Mm
- RSDr. Roger Seheult
... and maybe present them outside so that your immune system can kinda look at what's coming down the pike potentially and be ready for it with antibodies, so when that virus really comes in- The antibodies can cover it, can, uh, prevent it from, uh, uh, spreading, and you can basically suppress the, the infection. And, and appar- apparently, course, according to the, uh, studies, it's 95% effective at doing that. This messenger RNA is like a, uh, it's like a, a sticky note. It's like a, you know those 3M yellow sticky things-
- SPSpeaker
Yeah
- RSDr. Roger Seheult
... you can put on?
- SPSpeaker
Yeah, yeah.
- RSDr. Roger Seheult
So I, I, I think it like your, your DNA is like your Social Security card. You, you don't laminate it, you put it in your filing cabinet, you never take it out.
- SPSpeaker
[laughs]
- RSDr. Roger Seheult
That, that number can do a lot of good things. You can apply for a loan, you pay your taxes with it. I- if you're let- you know, I, I have my number memorized. Some people don't, but if you ever had to use it, you would take it out, you'd look at it, you'd write it down on a sticky note. You put it down. You put the security card back, 'cause it's very important, and then you'd use that sticky note. And then, you know, after you're done with it, you'd rip it up and you'd throw it away. The messenger RNA is the sticky note, okay? It's there one day, it's gone the next.
- SPSpeaker
Hm.
- RSDr. Roger Seheult
Messenger RNA doesn't stick around. It doesn't last.
- SPSpeaker
Really?
- RSDr. Roger Seheult
No. No, it, it's there... It, that messenger RNA is telling the cell, "I want you to make this protein now."
- SPSpeaker
And then it goes away.
- RSDr. Roger Seheult
Cells, you don't... Right. You don't want the cells to be making that protein for the rest of their lives. You want the protein to be made when it needs to be made. A- and that's why it's so important that these proteins that go into the nucleus to tell what type of messenger RNA needs to be made have to be turned on and turned off. That's what vitamin D, uh, as we discussed, does, i- in many different s- senses. But the messenger RNA is there when you want the protein, it's gone when you don't want the protein.
- 1:22:12 – 1:30:26
Vaccines in General, Side Effects, Faith and Herd Immunity
- SPSpeaker
So do people need vaccines, uh, you know, to, to survive, to thrive, to be healthy in today's world? Should kids be getting the vaccine? Or, you know, can we still survive and live our lives without it? Before we continue this video, make sure to subscribe below and turn on the notification bell right now so you don't miss out on these great videos every single day.
- RSDr. Roger Seheult
Sometimes we take things for granted when we don't have them.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
Uh, what kind of a quality of life would you like to have, is the question. Uh, the fact that we don't have polio today, the fact that we don't have to worry about smallpox today, those are direct consequences of, of our ancestors in this country and around the world realizing that if they took this vaccine, we could eliminate those diseases.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
And, and we've effectively done that.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
When we in this country started to say that a vaccine choice for me, what, what's the, what's the stuff that goes into the integration of making a choice about whether or not I get the vaccine? And for some people, it's been, "Hey, if you, if you don't want your daughter to get HPV," you know, basically, uh, cervical cancer, "then get this vaccine. If you don't want your son who's going away to college to get, uh, meningitis, get this vaccine." A- a- and that's how I, uh... Honestly, that's how the, the, the pharmaceutical companies have marketed these vaccines, is this vaccine is going to help you. What we've completely forgotten, I think, is how vaccines help us.
- SPSpeaker
Hm.
- RSDr. Roger Seheult
Us as individuals. So we ha- we got, all of us have gotten the benefits because our ancestors, maybe our grandparents, got the polio vaccine and the smallpox vaccine.
- SPSpeaker
And they didn't spread it.
- RSDr. Roger Seheult
'Cause we essentially eliminated it. Yeah.
- SPSpeaker
They didn't spread it, yeah.
- RSDr. Roger Seheult
It's, it's eliminated. It's gone. It's not even, it's not really even a risk at this point, right? We, we-
- SPSpeaker
Because they got vaccinated, and so-
- RSDr. Roger Seheult
Ex-
- SPSpeaker
Since they didn't-
- RSDr. Roger Seheult
Exactly
- SPSpeaker
... spread it and kill more people, we don't have it anymore.
- RSDr. Roger Seheult
And it, it got eliminated.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
It's because everybody si- so, so it's kind of gestalt, right? Gestalt, by definition, is when the sum of the parts are greater than all of the sum of the parts, right?
- SPSpeaker
Mm-hmm. Wow.
- RSDr. Roger Seheult
The, the greater is greater than the sum of the parts.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
So, so yes, there is a benefit to the recipient of the vaccine, but there is something bigger, there is something bigger in, in the, that we all get as a derived benefit when everybody gets the vaccine, and that is the elimination of the disease or the near elimination of the disease.
- SPSpeaker
What are the negative effects, potential negative effects? Obviously, we haven't had, uh, enough time to really test this, but what could be the negative effects of taking the vaccine? What, what could that-
- RSDr. Roger Seheult
Oh
- SPSpeaker
... do potentially to the body?
- RSDr. Roger Seheult
So there, the... So yeah, I- I'm not gonna tell you that this is a panacea. There are, there are... First of all, there are common reactions that can occur when you get the vaccine. So this basically is your immune system. Your immune system is revving up. You're gonna feel bad when your interferon levels go up. Um-
- 1:30:26 – 1:43:04
Kids, Vaccines, Immune Exposure, and Further Immune Boosters
- SPSpeaker
I'm curious your thought. I wanna talk about kids again for a second, because obviously there's a lot of parents who are, um, you know, not sure about the, what's proper information, what should I do with my kids, all these things. Should kids at a certain age be getting this vaccine? Is that more dangerous to have young kids getting vaccines? And also, what's your thoughts on, in general, on protecting and trying to have your kids so perfectly clean, and never touched by anyone-
- RSDr. Roger Seheult
[laughs]
- SPSpeaker
... and always rubbed down with wipes and your face and-
- RSDr. Roger Seheult
Yeah
- SPSpeaker
... you know, sanitized life bubble versus allowing kids to be exposed to as much potential, uh, diversified, uh, organisms to build their immune system. What's your scientific thoughts on that?
- RSDr. Roger Seheult
Okay. So let's, uh, that's, that's a... [laughs] There's so many things that have just popped into my head.
- SPSpeaker
[laughs]
- RSDr. Roger Seheult
So let's, let's talk about, uh, the vaccine. So the vaccine is approved down to the age of 16 years of age right now. So, um, anybody over the age of 16 or above c- can get it. I think that's a reasonable thing to do. I would say That the reason for children or kids or young people to get the vaccine, although I have seen people in their 30s in the hospital, I have seen that, um, it's, it's more for, uh, herd immunity at that point. Because it's those children or those individuals that are gonna go to grandma and grandpa-
- SPSpeaker
Mm-hmm
- RSDr. Roger Seheult
... and spread it potentially. So to the degree that we have data now that shows that asymptomatic spread can be prevented by getting the vaccine, we do have some data on that, about 67% in the Moderna vaccine, for instance, uh, that would be, uh, helpful. I don't believe that a vaccine in a 16-year-old is going to do much in terms of preventing them from having hospitalization, 'cause they're not getting hospitalized then, right now. They're actually doing f- fine.
- SPSpeaker
So they're getting-
- RSDr. Roger Seheult
Less-
- SPSpeaker
... COVID-
- RSDr. Roger Seheult
Yeah
- SPSpeaker
... but they're just like n- no symptoms or-
- RSDr. Roger Seheult
Hardly any symptoms
- SPSpeaker
... very little. It's like, "Ah, I lost my taste, but I'm fine."
- RSDr. Roger Seheult
Yeah. A- a- and why is that? It's because young people have great innate immune systems.
- SPSpeaker
Mm-hmm.
- RSDr. Roger Seheult
Innate immune systems in children are very strong. I mean, any little virus, and what do they do? They get a fever.
- SPSpeaker
Mm.
- RSDr. Roger Seheult
I mean, most pediatric visits are for fevers, and that's because kids have great innate immune systems, and that's what we oughta be doing with adults, is trying to figure out how to improve their innate immune system.
- SPSpeaker
Mm.
- RSDr. Roger Seheult
Now, if you're going less than 16 years of age, in that situation, uh, you know, we need more data. A- a- and right now we don't have that data. They're looking at doing that. They're, they're actually doing the studies at this point. But even more so for the young kids, right? Because they're not, while there are some risks of getting post-infectious complications, like we, we saw this thing earlier last year about Kawasaki disease type of thing, uh, post-infectious type of things, it would be good. But I think the, the primary protection that we're getting there is preventing the spread to those that are gonna be ending up in the hospital. That's why the vaccination schedule that you're seeing, the 1A, 1B, 1C, 2, 3, et cetera, is starting out with these very critically elderly patients who are in nursing homes, for instance, who are the most susceptible to getting, uh, getting the disease.
- SPSpeaker
Yeah.
- RSDr. Roger Seheult
And, and, and, and probably the last people that'll be getting this vaccine will be those less than 16.
- SPSpeaker
And do you think-
- RSDr. Roger Seheult
Now, you als- yeah.
- SPSpeaker
Yeah.
- RSDr. Roger Seheult
What was the other thing you mentioned? Yeah.
- 1:43:04 – 1:52:19
Virus Variants, Closing Thoughts and the Three Truths
- SPSpeaker
And, and I've got a fin- a couple final questions here, but one is about, uh, new mutations of COVID impact-
- RSDr. Roger Seheult
Yeah
- SPSpeaker
... on the vaccine testing and treatments. If, uh, you know, you get the vaccine, and then there's a new mutation, will we need multiple vaccines? How will that impact those strands, those new strands, I guess?
- RSDr. Roger Seheult
Yeah, very good question. So the f- the four variants that we're looking at right now is the UK variant, which we found out first. There is a South African variant. There's a Brazilian variant, and then of course there's a variant here in the United States out of s- uh, out of San Jose. And so what we know as of today, um, we know that there is data that is just, that was just published yesterday that showed that the UK variant is gonna be just fine in terms of the coverage that we have with the current vaccine.
- SPSpeaker
Okay.
- RSDr. Roger Seheult
So that's good news, and, and that's despite mutations in the spike protein.
- SPSpeaker
Hmm.
- RSDr. Roger Seheult
We don't yet have that data for the South African or the Brazilian or the United States variant, but they are working on that currently. As it turns out, if- If those are go the way as the UK variant, we will not need to have a new vaccine. But if there is, if there's something called an escape mutation where, where the vaccine... where the, the virus is able to escape the immunity put on by the human body, here's, here's the, the silver lining there a little bit, is that all they would have to do is change the sequence of the messenger RNA in the vaccine that they're already giving to reflect the new structure of the, of the, of the spike protein. And so it would not take very long for that new vaccine to be developed.
- SPSpeaker
Gotcha.
- RSDr. Roger Seheult
The other thing I was gonna mention real quickly is that your immune system is so smart that it also, the, the, the, the cells that make the antibodies against that virus also have in it a slight mutation to anticipate, believe it or not, to anticipate that type of a mutation.
- SPSpeaker
That's crazy.
- RSDr. Roger Seheult
Yeah.
- SPSpeaker
The, the human body is fascinating.
- RSDr. Roger Seheult
Yes.
- SPSpeaker
This has been probably one of the most informative interviews I've done on this topic, definitely, and, uh, I'm just very grateful for your consistent research, testing, understanding, and access to this information to be able to share this with us. I know you're in the, uh, the hospital on a weekly basis treating people. I know you're, uh, constantly doing research on... and, and I know you're educating people over at MedCram.com with incredible data, uh, you know, information that is extremely helpful for people to understand this on the science, on the, on the medical side of things, and, uh, the practical tips that you give as well. So I just wanna acknowledge you, Dr. Seheult, for, for showing up in a big way for people and, and putting yourself out there and educating us with content, with videos, so that people can be more informed and, and hopefully make better decisions for what's right for them and their families, for their health. And, uh, I'm, again, I acknowledge you for, for doing it in an understandable way, where you can break down the data and the science, but then also, uh, give some good stories and analogies so that common people like myself can understand what, what you're talking about. Um, I want people to follow you over on social media. You're everywhere, MedCram Videos, Twitter, MedCram on Instagram, Facebook, and MedCram, C-R-A-M, .com. Lots of incredible videos over there. We'll have it linked up in the show notes. Where else can we go to connect with you or, or support you?
- RSDr. Roger Seheult
Well, that's it. You've just mentioned those. Uh, just, uh, yeah, it's, um, uh, thank you very much for inviting me on, uh, Lewis. It's been, uh, it's been amazing. And, uh, but yeah, uh, follow us on, on, uh, Twitter and also on, uh, uh, on the YouTube channel MedCram.
- SPSpeaker
Yeah, your YouTube is great. You got some amazing videos, and I'm sure they'll be linked up here as well.
- RSDr. Roger Seheult
And I'd also say, too, it's not just me on MedCram. We also get, uh, experts in the field. We recently had Shane Crotty, who is a, uh, a expert, um, virologist, immunologist down there at, uh, La Jolla, and recently, uh, Dr. Joseph Allen at the s- uh, Harvard School of Public Health. So we try to get experts in the field to talk, uh, and explain.
- SPSpeaker
Amazing. Yeah, I want everyone to check this stuff out, 'cause I think we're gonna need more of this information over the next year and beyond as things evolve in, in this, uh, this virus. Um, I wanna ask you a question I ask everyone at the end of my episodes. It's called the three truths question. It's a hypothetical question, and I'd like you to imagine you live a very long life, and it's your last day. And for whatever reason, all of the content you've ever created, all the stuff on MedCram, and anything else you create for the rest of your life, it has to go with you to the next place after you, you leave this earth. So no one has access to any of your information, but you get to leave behind three lessons you know to be true from your life and your existence that you've learned that you would leave with the world. And this is all we have to remember you by are these three lessons, or what I like to call the three truths. What would you say are yours?
- RSDr. Roger Seheult
I would say that whenever someone comes to you with something new, it's good to be skeptical-
- SPSpeaker
Mm-hmm
- RSDr. Roger Seheult
... and not be driven by every wind of, of, uh, of saying. But at the same time, at the same time that you're doing that, leave part of your mind open to the possibility that it can be true of, of what they're saying, and investigate it for yourself. Don't believe anybody. Be skeptical, but investigate it, 'cause it could be the truth.
- SPSpeaker
Yeah.
- RSDr. Roger Seheult
I, I... the reason why I say that is because we live in a world of information, and it's no longer a question about whether or not the truth is out there or whether we have to search for the truth or find the truth. The truth is there. The problem is, is expressing it and getting people to believe it, because there are so many alternative motives that people suspect other people of having that to, to be open-minded and to find it.
- SPSpeaker
That's number one.
- RSDr. Roger Seheult
Okay. [laughs] Uh, that was number one. Um-
- SPSpeaker
Number two, your second-
- RSDr. Roger Seheult
Num-
- SPSpeaker
... second truth.
- RSDr. Roger Seheult
Number two, I would say that, uh, you know, uh, I guess I'm informed by my, uh, by my upbringing and by my spirituality, and so I believe that, uh, uh, that good doesn't come from within, it, good comes from above.
Episode duration: 1:52:19
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