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Lex Fridman PodcastLex Fridman Podcast

Manolis Kellis: Biology of Disease | Lex Fridman Podcast #133

Manolis Kellis is a computational biologist at MIT.

Lex FridmanhostManolis Kellisguest
Oct 25, 20202h 34mWatch on YouTube

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Episode Details

EPISODE INFO

Released
October 25, 2020
Duration
2h 34m
Channel
Lex Fridman Podcast
Watch on YouTube
▶ Open ↗

EPISODE DESCRIPTION

Manolis Kellis is a computational biologist at MIT. Please support this podcast by checking out our sponsors:

EPISODE LINKS: Manolis Website: http://web.mit.edu/manoli/ Manolis Twitter: https://twitter.com/manoliskellis Manolis YouTube: https://www.youtube.com/channel/UCkKlJ5LHrE3C7fgbnPA5DGA Manolis Wikipedia: https://en.wikipedia.org/wiki/Manolis_Kellis PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ Full episodes playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 Clips playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOeciFP3CBCIEElOJeitOr41 OUTLINE: 0:00 - Introduction 2:49 - Molecular basis for human disease 26:48 - Deadliest diseases 32:31 - Genetic component of diseases 41:22 - Genetic understanding of disease 57:09 - Unified theory of human disease 1:03:10 - Genome circuitry 1:28:13 - CRISPR 1:39:50 - Mitochondria 1:47:54 - Future of biology research 2:17:30 - The genetic circuitry of disease CONNECT:

SPEAKERS

  • Lex Fridman

    host
  • Manolis Kellis

    guest
  • Narrator

    other
  • Narrator

    other
  • Narrator

    other
  • Narrator

    other

EPISODE SUMMARY

In this episode of Lex Fridman Podcast, featuring Lex Fridman and Manolis Kellis, Manolis Kellis: Biology of Disease | Lex Fridman Podcast #133 explores Decoding Human Disease: Genetics, Brain Circuits, and Future Therapies Lex Fridman and Manolis Kellis explore how modern human genetics and computational biology are transforming our understanding of complex diseases such as obesity, Alzheimer’s, schizophrenia, heart disease, and metabolic disorders.

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