Manolis Kellis: Human Genome and Evolutionary Dynamics | Lex Fridman Podcast #113

Manolis Kellis is a professor at MIT and head of the MIT Computational Biology Group. He is interested in understanding the human genome from a computational, evolutionary, biological, and other cross-disciplinary perspectives. Support this podcast by supporting our sponsors: - MasterClass: https://masterclass.com/lex - Eight Sleep: https://eightsleep.com/lex - Blinkist: https://blinkist.com/lex EPISODE LINKS: Manolis Website: http://web.mit.edu/manoli/ Manolis Twitter: https://twitter.com/manoliskellis Manolis Wikipedia: https://en.wikipedia.org/wiki/Manolis_Kellis PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ Full episodes playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 Clips playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOeciFP3CBCIEElOJeitOr41 OUTLINE: 0:00 - Introduction 3:54 - Human genome 17:47 - Sources of knowledge 29:15 - Free will 33:26 - Simulation 35:17 - Biological and computing 50:10 - Genome-wide evolutionary signatures 56:54 - Evolution of COVID-19 1:02:59 - Are viruses intelligent? 1:12:08 - Humans vs viruses 1:19:39 - Engineered pandemics 1:23:23 - Immune system 1:33:22 - Placebo effect 1:35:39 - Human genome source code 1:44:40 - Mutation 1:51:46 - Deep learning 1:58:08 - Neuralink 2:07:07 - Language 2:15:19 - Meaning of life CONNECT: - Subscribe to this YouTube channel - Twitter: https://twitter.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/LexFridmanPage - Instagram: https://www.instagram.com/lexfridman - Medium: https://medium.com/@lexfridman - Support on Patreon: https://www.patreon.com/lexfridman