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Manolis Kellis: Human Genome and Evolutionary Dynamics | Lex Fridman Podcast #113
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Manolis Kellis: Human Genome and Evolutionary Dynamics | Lex Fridman Podcast #113

Manolis Kellis is a professor at MIT and head of the MIT Computational Biology Group. He is interested in understanding the human genome from a computational, evolutionary, biological, and other cross-disciplinary perspectives.

Lex FridmanhostManolis Kellisguest
Jul 31, 20202h 29mWatch on YouTube ↗

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Episode Details

EPISODE INFO

Released
July 31, 2020
Duration
2h 29m
Channel
Lex Fridman Podcast
Watch on YouTube
▶ Open ↗

EPISODE DESCRIPTION

Manolis Kellis is a professor at MIT and head of the MIT Computational Biology Group. He is interested in understanding the human genome from a computational, evolutionary, biological, and other cross-disciplinary perspectives. Support this podcast by supporting our sponsors:

EPISODE LINKS: Manolis Website: http://web.mit.edu/manoli/ Manolis Twitter: https://twitter.com/manoliskellis Manolis Wikipedia: https://en.wikipedia.org/wiki/Manolis_Kellis PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ Full episodes playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 Clips playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOeciFP3CBCIEElOJeitOr41 OUTLINE: 0:00 - Introduction 3:54 - Human genome 17:47 - Sources of knowledge 29:15 - Free will 33:26 - Simulation 35:17 - Biological and computing 50:10 - Genome-wide evolutionary signatures 56:54 - Evolution of COVID-19 1:02:59 - Are viruses intelligent? 1:12:08 - Humans vs viruses 1:19:39 - Engineered pandemics 1:23:23 - Immune system 1:33:22 - Placebo effect 1:35:39 - Human genome source code 1:44:40 - Mutation 1:51:46 - Deep learning 1:58:08 - Neuralink 2:07:07 - Language 2:15:19 - Meaning of life CONNECT:

SPEAKERS

  • Lex Fridman

    host
  • Manolis Kellis

    guest

EPISODE SUMMARY

In this episode of Lex Fridman Podcast, featuring Lex Fridman and Manolis Kellis, Manolis Kellis: Human Genome and Evolutionary Dynamics | Lex Fridman Podcast #113 explores Digital Life, Human Genome, and Evolution’s Messy, Beautiful Intelligence Unveiled Lex Fridman and Manolis Kellis explore the human genome as a digital code underlying life, emphasizing how discrete genetic inheritance and massive variation shape both our individuality and shared humanity.

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