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Dr Rangan ChatterjeeDoctors Won't Tell You This - What Happens If You Don't Eat For 36 Hours | Dr. Pradip Jamnadas
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At a glance
WHAT IT’S REALLY ABOUT
Cardiologist Explains Fasting, Insulin, and Empowering Patients to Reverse Chronic Disease
- Dr. Jamnadas says he turned to fasting after finding that high insulin and insulin resistance, not cholesterol or blood sugar alone, appeared to underlie hardening of the arteries in many of his patients.
- He describes a gradual protocol: about three weeks of whole-food eating, then skipping meals, 18-hour fasts, one meal a day, 36-hour fasts, and finally three-day water fasts.
- He and Dr. Chatterjee discuss safety points, including adjusting blood pressure and insulin medications, eating disorders, addiction, and individual differences such as sleep apnea and women's responses.
- Dr. Jamnadas stresses that fasting empowers patients psychologically, giving them a sense of control, freedom from cravings, and a broader sense of who they are.
- He closes with four tips: eat natural foods, eat infrequently and only when hungry, sleep at least seven hours, and find pleasure in life.
IDEAS WORTH REMEMBERING
5 ideasHigh insulin was his central target
Dr. Jamnadas found patients with hardened arteries often had only mildly raised sugars but massive insulin responses, and he saw fasting as the way to bring insulin down without a drug.
Insulin affects blood pressure and fat storage
He says insulin depletes nitric oxide so vessels cannot dilate, and acts as a storage hormone, so lowering it let patients' blood pressure and weight fall, sometimes allowing medication reductions.
Fasting activates repair processes
He describes ketone production, autophagy, mitophagy, stem cell mobilization, rising growth hormone, BDNF, and lower inflammation as processes that occur or increase with fasting rather than in a fed state.
Go gradual, starting with diet
He first has patients cut sugar and processed foods for two to three weeks, then progress step by step, because going straight to long fasts led to higher failure rates, withdrawal, and keto flu.
Coronary calcium scoring can motivate prevention
He uses the CT calcium score to show asymptomatic patients they already have atherosclerosis, and links the same lifestyle changes to lower risk of dementia, kidney disease, and cancer.
WORDS WORTH SAVING
5 quotesYou are not your habits. You are not even your body. You are something that can change everything.
— Dr. Pradip Jamnadas
Because when you don't eat, guess what? You don't make insulin. That's it.
— Dr. Pradip Jamnadas
You fix the metabolism, the weight comes down as a side effect.
— Dr. Pradip Jamnadas
Fasting forgives you. Fasting, in a sense, forgives you for certain foods that, that you may then consume.
— Dr. Pradip Jamnadas
Be careful about your thoughts about who you are and how you're interacting with the world and everything that's going around you, because in an instantaneous moment, you're actually metabolizing it into physiology in your body.
— Dr. Pradip Jamnadas
High quality AI-generated summary created from speaker-labeled transcript.
