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The Impact of H1B Visas on Startups in the US & NVIDIA Invests $100BN Into OpenAI

Jason Lemkin is one of the leading SaaS investors of the last decade with a portfolio including the likes of Algolia, Talkdesk, Owner, RevenueCat, Saleloft and more. Rory O’Driscoll is a General Partner @ Scale where he has led investments in category leaders such as Bill.com (BILL), Box (BOX), DocuSign (DOCU), and WalkMe (WKME), among others. ----------------------------------------------- In Today’s Episode We Discuss: 00:00 Intro 01:17 Nvidia's Massive $100BN Investment in OpenAI 05:45 Is Anthropic Negatively Positioned by OpenAI Gaining NVIDIA Investment 22:24 Is Triple, Triple, Double, Double Dead 41:59 Navan Files to Go Public at $8BN 54:17 Lockup Periods and Liquidity 01:02:17 Impact of H-1B Visa Changes on Startups 01:07:40 Notion Hits $500M ARR Re-Accelerating 01:16:16 Why Founder Friendly is Total BS Today 01:19:48 Kalshi Quick-Fire Round ---------------------------------------------------------------------------------------------- Subscribe on Spotify: https://open.spotify.com/show/3j2KMcZ... Subscribe on Apple Podcasts: https://podcasts.apple.com/us/podcast... Follow Harry Stebbings on X: / harrystebbings Follow Jason Lemkin on X: / jasonlk Follow Rory O’Driscoll on X: / rodriscoll Follow 20VC on Instagram: / 20vchq Follow 20VC on TikTok: / 20vc_tok Visit our Website: https://www.20vc.com Subscribe to our Newsletter: https://www.thetwentyminutevc.com/con... ----------------------------------------------- #20vc #harrystebbings #roryodriscoll #jasonlemkin #openai #nvidia #navan #anthropic #notion

Jason LemkinguestHarry StebbingshostRory O’Driscollguest
Sep 25, 20251h 25mWatch on YouTube ↗

Episode Details

EPISODE INFO

Released
September 25, 2025
Duration
1h 25m
Channel
The Twenty Minute VC
Watch on YouTube
▶ Open ↗

EPISODE DESCRIPTION

Jason Lemkin is one of the leading SaaS investors of the last decade with a portfolio including the likes of Algolia, Talkdesk, Owner, RevenueCat, Saleloft and more. Rory O’Driscoll is a General Partner @ Scale where he has led investments in category leaders such as Bill.com (BILL), Box (BOX), DocuSign (DOCU), and WalkMe (WKME), among others. ----------------------------------------------- In Today’s Episode We Discuss: 00:00 Intro 01:17 Nvidia's Massive $100BN Investment in OpenAI 05:45 Is Anthropic Negatively Positioned by OpenAI Gaining NVIDIA Investment 22:24 Is Triple, Triple, Double, Double Dead 41:59 Navan Files to Go Public at $8BN 54:17 Lockup Periods and Liquidity 01:02:17 Impact of H-1B Visa Changes on Startups 01:07:40 Notion Hits $500M ARR Re-Accelerating 01:16:16 Why Founder Friendly is Total BS Today 01:19:48 Kalshi Quick-Fire Round ---------------------------------------------------------------------------------------------- Subscribe on Spotify: https://open.spotify.com/show/3j2KMcZ... Subscribe on Apple Podcasts: https://podcasts.apple.com/us/podcast... Follow Harry Stebbings on X: / harrystebbings Follow Jason Lemkin on X: / jasonlk Follow Rory O’Driscoll on X: / rodriscoll Follow 20VC on Instagram: / 20vchq Follow 20VC on TikTok: / 20vc_tok Visit our Website: https://www.20vc.com Subscribe to our Newsletter: https://www.thetwentyminutevc.com/con... ----------------------------------------------- #20vc #harrystebbings #roryodriscoll #jasonlemkin #openai #nvidia #navan #anthropic #notion

SPEAKERS

  • Jason Lemkin

    guest

    SaaS-focused investor and founder of SaaStr, known for commentary on venture markets and startup scaling.

  • Harry Stebbings

    host

    Founder and host of The Twenty Minute VC (20VC), interviewing leading investors and founders.

  • Rory O’Driscoll

    guest

    Venture capitalist and longtime board-level investor with experience in fund construction and IPO/liquidity dynamics.

EPISODE SUMMARY

In this episode of The Twenty Minute VC, featuring Jason Lemkin and Harry Stebbings, The Impact of H1B Visas on Startups in the US & NVIDIA Invests $100BN Into OpenAI explores aI mega-financing, venture concentration, IPO mechanics, and H-1B headwinds debated The panel frames NVIDIA’s reported $100B OpenAI investment as a ‘let’s find out’ experiment that extends the scaling-laws bet by removing near-term capital constraints, while warning the economics may rely on heroic assumptions.

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