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Peter Attia MDPeter Attia MD

#117 – Stanley Perlman, M.D., Ph.D.: Insights from a coronavirus expert on COVID-19

Original release date: 6/29/20 In this episode Stanley Perlman shares insights from his impressive career studying coronaviruses–both the common and more deadly ones, like MERS and SARS. In comparing preceding coronaviruses with SARS-CoV-2, Stanley discusses how other coronaviruses can aid our current understanding of, and be used to infer about, COVID-19. He also gives his thoughts on durable immunity, therapeutic strategies, and future outbreak preparedness. We discuss: 00:00:00 - Intro 00:02:45 - His background and early work with coronaviruses 00:09:00 - Coronavirus family—various types, common traits, and scientific understanding 00:17:45 - The origin of viruses, animal to human transmission, R_0, immunity, and more 00:28:30 - Insights from the 2002 SARS outbreak 00:35:00 - Insights from the 2012 MERS outbreak 00:42:00 - Comparing SARS-CoV-2 to MERS, SARS, and other coronaviruses 00:53:30 - COVID-19 survivor potential for long-term damage 00:57:00 - Using the current pandemic for lessons on future preparedness 01:07:00 - Genetic drift and the potential for long-term immunity to COVID-19 01:22:30 - Prevention and treatment strategies for COVID-19 and future diseases 01:32:30 - Alternative hypothesis to the origin of SARS-CoV-2 01:34:30 - Determining durable immunity to COVID-19 and what a successful vaccine looks like Show notes page: https://peterattiamd.com/stanleyperlman/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 30 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life). Learn more: https://peterattiamd.com/ Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Play: http://bit.ly/TheDriveGooglePlay

Peter AttiahostStanley Perlmanguest
Jul 9, 20201h 43mWatch on YouTube ↗

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Episode Details

EPISODE INFO

Released
July 9, 2020
Duration
1h 43m
Channel
Peter Attia MD
Watch on YouTube
▶ Open ↗

EPISODE DESCRIPTION

Original release date: 6/29/20 In this episode Stanley Perlman shares insights from his impressive career studying coronaviruses–both the common and more deadly ones, like MERS and SARS. In comparing preceding coronaviruses with SARS-CoV-2, Stanley discusses how other coronaviruses can aid our current understanding of, and be used to infer about, COVID-19. He also gives his thoughts on durable immunity, therapeutic strategies, and future outbreak preparedness. We discuss: 00:00:00 - Intro 00:02:45 - His background and early work with coronaviruses 00:09:00 - Coronavirus family—various types, common traits, and scientific understanding 00:17:45 - The origin of viruses, animal to human transmission, R_0, immunity, and more 00:28:30 - Insights from the 2002 SARS outbreak 00:35:00 - Insights from the 2012 MERS outbreak 00:42:00 - Comparing SARS-CoV-2 to MERS, SARS, and other coronaviruses 00:53:30 - COVID-19 survivor potential for long-term damage 00:57:00 - Using the current pandemic for lessons on future preparedness 01:07:00 - Genetic drift and the potential for long-term immunity to COVID-19 01:22:30 - Prevention and treatment strategies for COVID-19 and future diseases 01:32:30 - Alternative hypothesis to the origin of SARS-CoV-2 01:34:30 - Determining durable immunity to COVID-19 and what a successful vaccine looks like Show notes page: https://peterattiamd.com/stanleyperlman/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 30 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life). Learn more: https://peterattiamd.com/ Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Play: http://bit.ly/TheDriveGooglePlay

SPEAKERS

  • Peter Attia

    host

    Physician and host of The Drive podcast focused on medicine, health, and longevity.

  • Stanley Perlman

    guest

    MD, PhD pediatric infectious disease physician-scientist and coronavirus researcher.

EPISODE SUMMARY

In this episode of Peter Attia MD, featuring Peter Attia and Stanley Perlman, #117 – Stanley Perlman, M.D., Ph.D.: Insights from a coronavirus expert on COVID-19 explores coronavirus Expert Perlman Explains SARS, MERS, COVID-19, Immunity and Preparedness Perlman traces his path from PhD training to medical school and pediatric infectious disease, where he studied coronaviruses in mice as a model for demyelinating disease similar to multiple sclerosis.

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