#24 – Tom Dayspring, M.D., FACP, FNLA – Part V of V: Lp(a), inflammation, oxLDL, remnants, and more

ℹ️ EPISODE INFO

Released

January 1, 2020

Duration

1h 29m

Channel

Peter Attia MD

Watch on YouTube

▶ Open ↗

📝 EPISODE DESCRIPTION

Original release date: 10/19/2018 In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter’s most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part V, Peter and Tom talk about inflammation, endothelial health, and oxidative stress as they pertain to cardiovascular disease, and our attempts to monitor them using biomarkers. They also discuss a couple of very important risk factors that too few people (and doctors) know about. Tom closes the five-part series with a tragic story about his good friend that is likely all-too-common for many practicing physicians, that both haunts and motivates Dr. Dayspring to learn as much as he can about the number one killer in the United States. We discuss: -Lp(a) [2:30]; -Inflammation [17:15]; -Oxidative stress markers: Lp-PLA2 and oxLDL [20:45]; -Endothelial health markers: ADMA and SDMA [34:30]; -Remnants [43:45]; -Omega-3 fatty acids (EPA and DHA) and apoC-III [55:30]; -Red blood cells and cholesterol transport [1:07:45]; -Tom’s friend Earl [1:10:00]; -Peter’s friend JP [1:18:15]; and -More. Show notes page: https://peterattiamd.com/tomdayspring5/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 10 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is the founder of Attia Medical, PC, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity. The practice applies nutritional biochemistry, exercise physiology, sleep physiology, techniques to increase distress tolerance, lipidology, pharmacology, and four-system endocrinology to increase lifespan (delaying the onset of chronic disease), while simultaneously improving healthspan (quality of life). Learn more: https://peterattiamd.com/ Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Play: http://bit.ly/TheDriveGooglePlay

🎤 SPEAKERS

• Dr. Tom Dayspring

  guest

  Lipidologist and educator known for deep expertise in lipoproteins, atherosclerosis, and cardiovascular risk markers.

🧾 EPISODE SUMMARY

In this episode of Peter Attia MD, featuring Dr. Peter Attia and Dr. Tom Dayspring, #24 – Tom Dayspring, M.D., FACP, FNLA – Part V of V: Lp(a), inflammation, oxLDL, remnants, and more explores dayspring and Attia Close Lipidology Course: Lp(a), Oxidation, Remnants, Omega-3s Dayspring explains that statins don't lower Lp(a) because apo(a) production in the liver, not receptor clearance, is the main determinant, and that apo(a) may camouflage the LDL receptor binding domain on apoB.

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