
The Scary New Research On Sugar & How They Made You Addicted To It! Jessie Inchauspé | E243
Steven Bartlett (host), Jessie Inchauspé (guest), Narrator, Narrator, Narrator
In this episode of The Diary of a CEO, featuring Steven Bartlett and Jessie Inchauspé, The Scary New Research On Sugar & How They Made You Addicted To It! Jessie Inchauspé | E243 explores glucose Spikes, Sugar Addiction, And Simple Hacks That Transform Your Health Biochemist and author Jessie Inchauspé (the "Glucose Goddess") explains how everyday eating patterns create harmful blood sugar spikes that quietly drive fatigue, cravings, hormonal issues, mental health struggles, and long‑term disease. She links her own severe depersonalization and panic attacks after a traumatic back injury to unstable glucose, which launched her deep dive into biochemistry and continuous glucose monitoring.
Glucose Spikes, Sugar Addiction, And Simple Hacks That Transform Your Health
Biochemist and author Jessie Inchauspé (the "Glucose Goddess") explains how everyday eating patterns create harmful blood sugar spikes that quietly drive fatigue, cravings, hormonal issues, mental health struggles, and long‑term disease. She links her own severe depersonalization and panic attacks after a traumatic back injury to unstable glucose, which launched her deep dive into biochemistry and continuous glucose monitoring.
Inchauspé dismantles common nutrition myths (calories, fruit juice, “healthy” breakfasts) and shows how glucose affects mitochondria, insulin, aging, brain function, fertility, and weight regulation even in people without diabetes. She emphasizes that our biology is mismatched with today’s ultra-processed, sugar-saturated environment.
Most importantly, she offers practical, low-friction “glucose hacks” that let people keep eating foods they love while dramatically reducing glucose spikes—such as changing food order, adding veggie starters, choosing savory breakfasts, using vinegar, and moving after meals. The conversation blends hard science with emotional vulnerability about health, family, and the importance of learning to "fly" your own body.
The episode positions glucose balance as a foundational lever for physical and mental health, arguing that understanding a few simple principles can cut through diet confusion, reduce shame around cravings, and help people partner with their bodies instead of fighting them.
Key Takeaways
Glucose Spikes Quietly Drive Everyday Symptoms And Long-Term Disease
Even without diabetes, most people experience frequent blood sugar spikes that manifest as cravings, afternoon crashes, brain fog, poor sleep, skin issues, and hormonal problems. ...
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Your Body Isn’t Sabotaging You—Cravings Are Biochemical, Not Moral Failures
When you eat sugar or refined starch, your glucose rises sharply then crashes. ...
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Think Less About Calories, More About What Food Does To Your Glucose
Calories were originally measured by literally burning food in a sealed device and seeing how much they heat water—an approach that says nothing about hormones, inflammation, or how you feel. ...
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Simple Eating-Order And Composition Hacks Dramatically Flatten Glucose Spikes
Eating in the sequence “veggies first, then proteins and fats, starches and sugars last” can reduce a meal’s glucose spike by up to ~75% without changing what or how much you eat. ...
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Savory Breakfasts Set Up A Stable Day; Sweet Breakfasts Trigger Rollercoasters
Breakfast is a key determinant of your day’s glucose pattern. ...
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Vinegar And Post-Meal Movement Are Powerful, Easy Tools
A tablespoon of vinegar diluted in a tall glass of water before eating can lower the glucose spike of that meal by up to 30% and the insulin response by ~20%. ...
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Modern “Healthy” Choices Like Fruit Juice Can Be Metabolic Traps
Today’s fruit is already bred to be larger and sweeter than ancestral varieties; when it is juiced, blended, or dried, the protective fiber is removed or destroyed and the sugar is concentrated. ...
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Notable Quotes
“If you don't have your health, you really don't have much.”
— Jessie Inchauspé
“The more spikes you have, the faster you die.”
— Jessie Inchauspé
“Sugar gives you pleasure; it does not give you energy.”
— Jessie Inchauspé
“Learn the glucose hacks and then just eat everything you love.”
— Jessie Inchauspé
“Most of us are unknowingly eating in a way that causes many of the symptoms we suffer from on a daily basis.”
— Jessie Inchauspé
Questions Answered in This Episode
You mentioned capturing a glucose spike that directly triggered a depersonalization episode—what did that specific meal or situation look like, and what did you change immediately afterward?
Biochemist and author Jessie Inchauspé (the "Glucose Goddess") explains how everyday eating patterns create harmful blood sugar spikes that quietly drive fatigue, cravings, hormonal issues, mental health struggles, and long‑term disease. ...
Get the full analysis with uListen AI
If someone with PCOS or fertility challenges applied your hacks consistently for 12 weeks, what biomarkers or symptoms would you expect to shift first, and how would you track progress?
Inchauspé dismantles common nutrition myths (calories, fruit juice, “healthy” breakfasts) and shows how glucose affects mitochondria, insulin, aging, brain function, fertility, and weight regulation even in people without diabetes. ...
Get the full analysis with uListen AI
You argue that fruit juice is metabolically similar to soda; how do you respond to nutritionists who still recommend 100% fruit juice for children or as part of a "balanced" breakfast?
Most importantly, she offers practical, low-friction “glucose hacks” that let people keep eating foods they love while dramatically reducing glucose spikes—such as changing food order, adding veggie starters, choosing savory breakfasts, using vinegar, and moving after meals. ...
Get the full analysis with uListen AI
For people who lift weights or are athletes and rely on carbs around training, how would you adapt your glucose hacks so they can perform optimally without compromising long-term metabolic health?
The episode positions glucose balance as a foundational lever for physical and mental health, arguing that understanding a few simple principles can cut through diet confusion, reduce shame around cravings, and help people partner with their bodies instead of fighting them.
Get the full analysis with uListen AI
Do you worry that focusing on glucose could become another form of orthorexia or food anxiety for some people, and what practical boundaries or mindsets do you recommend to keep this empowering rather than obsessive?
Get the full analysis with uListen AI
Transcript Preview
I'm gonna be completely honest with you here. It's important. (dramatic music) I thought the subject matter of glucose was ******* boring until I read your book, and then I was like, "Oh, my God."
(laughs)
(laughs)
(laughs) Jessie Inchauspé- The Glucose Goddess- ... is a biochemist. An author. Teaching us the best hacks to eat right. Without giving up the foods that we love.
Glucose is your body's favorite source of energy. Your brain cells are using glucose to think, speak, move. So when you flood your body with too much glucose too quickly, what happens is what I call a glucose spike. The more spikes you have, the faster you die.
In your book, you talk about these 10 hacks.
Yeah.
Eat food in the right order.
Yeah.
After you eat, move. Drink vinegar before you eat.
Yeah.
You're such a weirdo.
(laughs)
(laughs)
(laughs)
Learn the glucose hacks and then just eat everything you love. Like that's the thing you have to understand.
Wh- why do you care about this stuff?
Well, I went through my own sort of health journey. It was awful. And I was like, "I need to figure out how to fix myself." Like, "I need to understand what's going on because otherwise I just don't wanna live anymore." It was really to that point. I was like, "Either I figure out how to fix this or this is just too painful of an existence."
Before this episode starts, I have a small favor to ask from you. Two months ago, 74% of people that watch this channel didn't subscribe. We're now down to 69%. My goal is 50%. So if you've ever liked any of the videos we've posted, if you like this channel, can you do me a quick favor and hit the subscribe button? It helps this channel more than you know. And the bigger the channel gets, as you've seen, the bigger the guests get. Thank you and enjoy this episode. (upbeat music) Jessie.
Steven.
What is it that you do and why does it matter?
(sighs) I teach people about how food impacts their body, and it matters because most of us are unknowingly eating in a way that causes many of the symptoms that we suffer from on a daily basis. So it matters because once people understand how their dietary habits are impacting them, and once they make change, their whole universe upgrades. All of the things that they thought were just who they were, you know, the poor energy, the cravings, the acne, the bad sleep, the hormonal issues, all of a sudden, they can vanish. And so they kind of reconnect with their true selves once they're past all of those symptoms.
Wh- why do you care about this stuff?
(sighs) Many different reasons. Um, one is a personal story. The other is because I see a lot of people suffering from diseases that they don't understand and that unknowingly they're making worse. Mi- one big examples f- one big example for me is people who have type 2 diabetes, and a lot of people who have type 2 diabetes are eating in a way that's making it worse, but they think they're eating in a way that's good for them. And that breaks my heart into pieces, you know? I wanna give people the power back. I wanna give people the information back because the landscape we live in, you know, the, the marketing messages about food, all the confusing packaging, the confusing advice, the fads, that's really destructive. And so I wanna help people, like, clean all that up.
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