
Overcoming Depression, Burnout, Anxiety and Insomnia with Dan Murray-Serter | E54
Steven Bartlett (host), Dan Murray-Serter (guest), Narrator
In this episode of The Diary of a CEO, featuring Steven Bartlett and Dan Murray-Serter, Overcoming Depression, Burnout, Anxiety and Insomnia with Dan Murray-Serter | E54 explores entrepreneur Dan Murray-Serter’s Toolkit For Mental Health And Meaningful Success Dan Murray-Serter shares a deeply personal journey through bulimia, depression, burnout, anxiety and insomnia, and how those struggles ultimately led him to launch brain-health brand Heights. He explains how unprocessed trauma, misaligned startups, and hustle culture contributed to his collapse, and how spirituality and psychedelics, especially ayahuasca, helped him rebuild belief, purpose and resilience.
Entrepreneur Dan Murray-Serter’s Toolkit For Mental Health And Meaningful Success
Dan Murray-Serter shares a deeply personal journey through bulimia, depression, burnout, anxiety and insomnia, and how those struggles ultimately led him to launch brain-health brand Heights. He explains how unprocessed trauma, misaligned startups, and hustle culture contributed to his collapse, and how spirituality and psychedelics, especially ayahuasca, helped him rebuild belief, purpose and resilience.
The conversation explores practical systems for mental well‑being: nutrition for the brain, designing habits, scheduling rest, and treating both business and marriage with clear values, OKRs, and long‑term vision. Dan and Steven also dissect impostor syndrome, personal branding fears, and the identity shifts that come with entrepreneurship and leaving religion.
Underlying the episode is a redefinition of success away from money, image and external validation, towards contribution, learning, aligned work, and honest relationships—with oneself, with partners, and with work.
Key Takeaways
Unprocessed mental health issues can stay buried—even from yourself
Dan only consciously recognised that he’d been bulimic years after it stopped, despite hospitalisation from a vomiting‑related throat injury. ...
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Purpose misalignment is a major driver of burnout
Dan’s worst burnout came while running Grabble, a fast‑growing fashion startup he admits he never truly cared about. ...
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Nutrition can meaningfully affect anxiety, sleep and mental performance
After six months of crippling insomnia and anxiety unhelped by therapy apps or lifestyle tweaks, a dietitian identified Dan’s likely brain‑food deficiencies and prescribed high‑quality omega‑3 (DHA), B vitamins and blueberry extract. ...
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Psychedelics, used correctly, can catalyse profound, lasting change
Following his father’s death, Dan lost all spiritual belief and spent years in a nihilistic depression. ...
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Design systems and environments that make good habits automatic
To overcome impostor syndrome in neuroscience and nutrition, Dan committed to reading and summarising one brain‑science paper weekly for 100+ weeks, turning learning into a non‑negotiable ritual. ...
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Treat relationships with the same intentionality as a company
Dan and his wife run their marriage with an explicit long‑term “objective” (a fulfilling 50‑year partnership) and shared OKRs across mind, body and soul. ...
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Redefine success around contribution and learning, not outcomes
Despite Grabble’s failure and Heights’ inherent risk, Dan isn’t deterred from founding again because he defines success as being a “lifelong intern”—constantly learning, contributing and growing—rather than as company valuations or exits. ...
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Notable Quotes
“Sometimes these things are so painfully embarrassing about your personal life that you can even bury it to yourself.”
— Dan Murray-Serter
“If you don’t have a sense of belief, it’s really hard to find your purpose.”
— Dan Murray-Serter
“It isn’t always about what you want… it’s actually about having gratitude for what you have. And when you have enough gratitude for what you already have, you will unlock the path to more.”
— Dan Murray-Serter
“You’re not paid for your stamina… I’m paid for my decision‑making. And overworking and burnout are bad decision‑making.”
— Dan Murray-Serter
“If you can’t be the CEO of your body, you do not earn the right to be the CEO of your company.”
— Dan Murray-Serter
Questions Answered in This Episode
You described ayahuasca as the single most important thing you’ve ever done. If it were ever legal and clinically available, how would you design an ideal protocol for someone with treatment‑resistant depression who’s never touched psychedelics before?
Dan Murray-Serter shares a deeply personal journey through bulimia, depression, burnout, anxiety and insomnia, and how those struggles ultimately led him to launch brain-health brand Heights. ...
Get the full analysis with uListen AI
When you and your co‑founder wrote brutally honest letters about Grabble’s failure, what was one specific behaviour change you each committed to—and how do you actively monitor that in your working relationship at Heights today?
The conversation explores practical systems for mental well‑being: nutrition for the brain, designing habits, scheduling rest, and treating both business and marriage with clear values, OKRs, and long‑term vision. ...
Get the full analysis with uListen AI
You’ve shown that nutrition transformed your insomnia and anxiety, but you also acknowledge the placebo problem. If Heights had zero supplement product tomorrow, how would you continue to deliver measurable brain‑health improvements purely through content, tools and community?
Underlying the episode is a redefinition of success away from money, image and external validation, towards contribution, learning, aligned work, and honest relationships—with oneself, with partners, and with work.
Get the full analysis with uListen AI
Your marriage OKRs are very structured. How do you stop those daily checklists from becoming another performance metric that you or your wife feel guilty about, rather than a genuine expression of love and care?
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You’re very critical of stealth‑mode startups and hustle culture. Can you share a recent decision at Heights—either saying ‘no’ to an opportunity or deliberately revealing something early—that most traditional founders would strongly disagree with, and why you think they’re wrong?
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Transcript Preview
It's very rare that you get to meet entrepreneurs that are following and have followed in the steps that y- you've followed in, in your life. And, like, so whenever I meet people like you and Ben Francis, who is similar age to me, who has, like, similar life ambitions, um, I see it as, like, this really amazing, rare opportunity to learn for myself and to ask honestly, like, selfish questions. And w- I saw on your Twitter, I think it was over the Mental Health Week period, you did a tweet where you talked about your experiences with depression, burnout, and anxiety. And from what I know about your story, you experienced those things in that order.
Yep.
So I think that's a good place to start, which is, let's talk about depression and the, the, the role that depression played in your life and where it came from and how you've overcome or are overcoming or handling depression.
Yeah. So interesting actually, because, um, I, I realized when I started to talk about mental health stuff, even more interestingly than what you've just said, I kind of realized that I'd been burying another mental health problem. So actually the, the tweet was more depression, burnout, anxiety, um, and insomnia.
Mm-hmm.
But actually, it's really interesting, I did a, a podcast interview with a nutritionist called Rhianon Lambert, and when I was preparing for that, I was going over my, the fact that I'd grown up fat and the fact that, um, you know, I probably did have an, an unusual, uh, relationship mentally with food.
(laughs)
And, um, suddenly, like, I was unpacking what had happened in my 20s, and I actually had bulimia.
Mm-hmm.
Um, I used to throw up for, like, four to five years, not intentionally though, this was, I, like, quite unusual, but that's how deeply rooted this mental health problem was. I would eat something and I would throw a lot of it up. Um, my friends would, like, know about this, but it wasn't, like, labeled, and I went to, you know, specialists in Harley Street to see what was up, and they were like, "Medically, you're fine. So psychologically there's something there." Anyway, I haven't done it since I was about 26 or whatever, but it suddenly occurred to me a few weeks ago, really interestingly, that, you know, being able to label, like, the time I got depression, the time I got anxiety, the time I got insomnia, the time I was burnt out, I remembered those moments. This one, I'd actually buried as a story-
Mm-hmm.
... right in my head and never, I'd never expressed it in my whole life to anyone publicly at all, full stop. Um, and it was a couple of months ago, and I wrote a newsletter on mental health and, uh, and nutrition, um, and I admitted for the first time then that I'd had bulimia, and what the symptoms were, and how long it had gone on, and the fact that I was basically, like, losing lots of weight, getting really skinny, and all I saw was someone fat.
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