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I've PROVEN This Food Keeps You Young & This Oil Reduces Inflammation by 85%! Bryan Johnson

If you enjoyed this episode, I recommend you check out my first conversation with Bryan Johnson, which you can find here: https://www.youtube.com/watch?v=1yfoonW1InE 00:00 Intro 02:17 Blueprint: The Study to Reverse Your Age 05:24 A Scientific & Measurable Perspective on My Health & the World 07:39 First Person To Achieve Perfect Sleep for 6 Months 13:48 How To Achieve Perfect Sleep 16:49 The Ultimate Effort to Not Die 23:56 What Are the Consequences of Extending Our Lives? 26:56 Brain Scans & My Psychedelic Experience 36:52 The Most Compelling Argument Against Blueprint 39:42 The Endless Possibilities of Genetic Engineering 42:18 High Street Supplements for Anti-Aging: What Really Works 49:07 The Surprising Impact of Nighttime Erections 01:01:00 Reversing Hair Loss 01:05:52 Testing the Human Blueprint Program on Others 01:14:02 Becoming the Top 7% Fittest in My Age Group 01:15:13 Balancing the Blueprint Program and My Former Social Life 01:17:55 The Toughest Sacrifices Made 01:21:38 Do You Want To Die? 01:24:04 Achievements Since Your Last Show Appearance 01:27:25 Creating the Ultimate Supplements for Every Individual 01:29:41 What Do You Disagree About with Bryan? 01:31:24 A Special Message from Bryan to the DOAC Community 01:32:54 Managing Online Hate 01:37:54 An Analogy for Our Future You can follow all the work and progress of Bryan and Blueprint here: https://bit.ly/3QP8VF2 Follow Bryan: Instagram: https://bit.ly/3rTLMaF Twitter: https://bit.ly/47hUDDi My new book! 'The 33 Laws Of Business & Life' is out now: https://smarturl.it/DOACbook Flightfund: https://flightfund.com/ Listen on: Apple podcast - https://podcasts.apple.com/gb/podcast/the-diary-of-a-ceo-by-steven-bartlett/id1291423644 Spotify - https://open.spotify.com/show/7iQXmUT7XGuZSzAMjoNWlX Join this channel to get access to perks: https://www.youtube.com/channel/UCGq-a57w-aPwyi3pW7XLiHw/join FOLLOW ► Instagram: https://www.instagram.com/steven/ Twitter: https://x.com/StevenBartlett?s=20 Linkedin: https://www.linkedin.com/in/steven-bartlett-56986834/ Sponsors: British Airways: https://www.britishairways.com/en-gb/offers/sale UNTIL: https://until.co.uk Huel: https://g2ul0.app.link/G4RjcdKNKsb

Steven BartletthostBryan JohnsonguestKate Dolloguest
Nov 8, 20231h 43mWatch on YouTube ↗

At a glance

WHAT IT’S REALLY ABOUT

Bryan Johnson’s Data-Driven Blueprint To Rebuild Body, Brain, And Future

  1. Bryan Johnson returns to detail the results of his Blueprint anti-aging protocol, claiming a 30% increase in projected lifespan, a 12‑year biological age reduction, maximal sleep metrics, and major gains in strength and cognition. He argues that modern humans are ‘half drunk’ on poor sleep, processed food, and cultural myths like grind culture, and that algorithmic, data-driven living can dramatically improve health and emotional stability.
  2. Central to his current stack are perfect sleep, rigorous measurement of thousands of biomarkers, targeted supplements (including sustained NAD support), and what he calls a ‘super of superfoods’: high‑polyphenol extra virgin olive oil. He also discusses cutting‑edge interventions like gene therapy, brain measurement via Kernel, psychedelic studies, and shockwave therapy for sexual function.
  3. Kate Tollo, his chief marketing officer and the first woman to follow Blueprint, shares how 90 days on the protocol transformed her fitness, blood markers, and sleep, while forcing her to confront deep‑seated people-pleasing and ‘priority Kate’ issues. The conversation repeatedly returns to the philosophical stakes: Johnson believes we are on the cusp of superintelligence and that aggressive life‑extension now may be the only way to experience that future.
  4. Throughout, they present Blueprint as both a personal discipline system and a species‑level experiment, making large parts of the protocol and recipes free while preparing a commercial stack intended to be “the most nutritious product in history.”

IDEAS WORTH REMEMBERING

5 ideas

Prioritize sleep as the single highest-leverage behavior change.

Johnson frames sleep as “the single most important thing any human does on any given day,” arguing that sleep deprivation is physiologically equivalent to alcohol intoxication. He achieved six months of 100% sleep scores using strict bedtimes (8:30 pm), early final meals (around 11 am), and designing his life around sleep, not vice versa. He stresses the difference between believing sleep matters and actually reorganizing your schedule, social life, and identity (e.g., leaving events early, refusing late meals) around it.

Use measurement to replace stories and self-deception with data.

Johnson sees humans as “self-deception machines” who over-trust narratives about themselves. His approach is to numerically model phenomena—like sleep quality, aging speed, NAD levels, erectile function, and brain patterns—instead of relying on feelings or cultural stories. Tools he cites include wearables (Whoop) for sleep and HRV, epigenetic aging blood tests, erection trackers for nighttime erectile quality, MRI for muscle and fat, and Kernel’s brain helmet for neural patterns.

High‑polyphenol extra virgin olive oil is a deeply evidence-backed ‘superfood’—but quality is critical.

Johnson allocates ~15% of his daily calories to verified high‑polyphenol EVOO, calling it “the super of superfoods.” Citing studies, he claims daily intake (~30–60 ml) can: reduce invasive breast cancer risk by >60%, cut post‑meal blood glucose by ~60%, and reduce oxidized LDL (a highly damaging particle) by ~80%. He emphasizes that most supermarket olive oils don’t meet the polyphenol and quality thresholds and thus likely don’t confer these benefits, which is why he built a vetted supply chain and product.

Sustained intracellular NAD support appears beneficial; one‑off IV drips are likely wasted effort.

Johnson criticizes NAD+ drips as a classic example of wellness theater: expensive, impressive‑looking, but not matched to pharmacokinetics or measured outcomes. His team measures intracellular NAD and has tested NMN and NR orally, twice daily, to maintain his NAD at an estimated ‘18‑year‑old’ level. Without sustained elevation (and without measuring your own levels), he suggests NAD drips are more marketing than medicine.

Sexual function and nighttime erections are powerful, underused health metrics.

He uses a ring‑style device to quantify nighttime erections—frequency, duration, and rigidity—linking them to cardiovascular, psychological, and sexual health. His current average is ~2 hours 12 minutes of nocturnal erection time; he estimates ~3.5 hours would correspond to an 18‑year‑old profile. He’s pairing this measurement with focused shockwave therapy to the penis (a painful acoustic treatment already used in orthopedics and erectile dysfunction) and reports a subjectively ‘15 years younger’ penis, though he stresses the need for more objective data.

WORDS WORTH SAVING

5 quotes

Sleep is the single most important thing any human does on any given day.

Bryan Johnson

The people who don’t sleep are literally half dead. They’re actually intoxicated.

Bryan Johnson

The one game every human on the planet is playing is ‘don’t die.’

Bryan Johnson

Extra virgin olive oil is like the super of superfoods.

Bryan Johnson

I want to have the opportunity to live.

Kate Tollo

The Blueprint protocol and measured results (sleep, aging, fitness)Sleep as foundational health and the mythology of grind cultureBiomarkers, gene therapy, and high‑polyphenol extra virgin olive oilBrain measurement, psychedelics, and Kernel’s ketamine studySexual health metrics: nighttime erections and shockwave therapyKate Tollo’s 90‑day Blueprint experience and psychological shiftsPhilosophy of death, superintelligence, and the future of humanity

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