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The Scary New Research On Sugar & How They Made You Addicted To It! Jessie Inchauspé | E243

In this episode, Steven interviews Jessie Inchauspé, a French biochemist and bestselling author. After breaking her back at 19, Jessie became interested in achieving optimal health. She worked at 23andMe and started the @glucosegoddess Instagram account, sharing her experiments with a glucose monitor. Her book 'Glucose Revolution' was published in 2022. (available to purchase here: https://bit.ly/3AFR4HR). Topics: 0:00 Intro 02:02 What is it that you do and why does it matter? 15:14 Why glucose? 26:45 The symptoms of bad glucose spikes 35:06 What is glucose? 38:06 What happens to our bodies when we have a glucose spike? 43:44 Glucose as it relates to weight gain 48:30 10 Hacks to prevent glucose spikes 01:02:14 The right meal to have for breakfast 01:09:26 Why you should be drinking vinegar 01:11:54 You have to be doing this after you eat 01:14:46 Your perfect diet 01:24:24 Our conversation cards 01:31:18 The last guest’s question Jessie is the author of the new book, ‘The Glucose Goddess Method’, which you can purchase here: https://bit.ly/41M9enc Follow: Instagram: https://bit.ly/3n89Pkg Our question cards waiting list: https://bit.ly/3ZzQfKz Join this channel to get access to perks: https://bit.ly/3Dpmgx5 Follow:  Instagram: http://bit.ly/3nIkGAZ Twitter: http://bit.ly/3ztHuHm Linkedin: http://bit.ly/3ZFGUku Telegram: http://bit.ly/3nJYxST Follow:  Instagram: http://bit.ly/3nIkGAZ Twitter: http://bit.ly/3ztHuHm Linkedin: https://bit.ly/41Fl95Q Telegram: http://bit.ly/3nJYxST Sponsors:  Zoe: http://joinzoe.com with an exclusive code CEO10 for 10% off Huel: https://g2ul0.app.link/G4RjcdKNKsb Wework: https://we.co/3PgoB1M

Steven BartletthostJessie Inchauspéguest
Apr 30, 20231h 35mWatch on YouTube ↗

At a glance

WHAT IT’S REALLY ABOUT

Glucose Spikes, Sugar Addiction, And Simple Hacks That Transform Your Health

  1. Biochemist and author Jessie Inchauspé (the "Glucose Goddess") explains how everyday eating patterns create harmful blood sugar spikes that quietly drive fatigue, cravings, hormonal issues, mental health struggles, and long‑term disease. She links her own severe depersonalization and panic attacks after a traumatic back injury to unstable glucose, which launched her deep dive into biochemistry and continuous glucose monitoring.
  2. Inchauspé dismantles common nutrition myths (calories, fruit juice, “healthy” breakfasts) and shows how glucose affects mitochondria, insulin, aging, brain function, fertility, and weight regulation even in people without diabetes. She emphasizes that our biology is mismatched with today’s ultra-processed, sugar-saturated environment.
  3. Most importantly, she offers practical, low-friction “glucose hacks” that let people keep eating foods they love while dramatically reducing glucose spikes—such as changing food order, adding veggie starters, choosing savory breakfasts, using vinegar, and moving after meals. The conversation blends hard science with emotional vulnerability about health, family, and the importance of learning to "fly" your own body.
  4. The episode positions glucose balance as a foundational lever for physical and mental health, arguing that understanding a few simple principles can cut through diet confusion, reduce shame around cravings, and help people partner with their bodies instead of fighting them.

IDEAS WORTH REMEMBERING

5 ideas

Glucose Spikes Quietly Drive Everyday Symptoms And Long-Term Disease

Even without diabetes, most people experience frequent blood sugar spikes that manifest as cravings, afternoon crashes, brain fog, poor sleep, skin issues, and hormonal problems. Over years, these spikes accelerate aging (via glycation), increase inflammation, and raise risk for type 2 diabetes, heart disease, dementia/Alzheimer’s (“type 3 diabetes”), cancer, and fertility issues such as PCOS. If you feel you “could feel better,” stabilizing glucose is one of the highest-leverage starting points.

Your Body Isn’t Sabotaging You—Cravings Are Biochemical, Not Moral Failures

When you eat sugar or refined starch, your glucose rises sharply then crashes. This post-spike drop directly activates the brain’s craving centers, pushing you to seek more sugar, often starting with breakfast and persisting all day. Sugar also releases dopamine, making it behaviorally addictive. Inchauspé argues that shame and “lack of willpower” narratives are misplaced: cravings largely reflect earlier food choices and brain chemistry, not character flaws.

Think Less About Calories, More About What Food Does To Your Glucose

Calories were originally measured by literally burning food in a sealed device and seeing how much they heat water—an approach that says nothing about hormones, inflammation, or how you feel. Two 2,000-calorie diets can have radically different effects depending on glucose dynamics: one can produce exhaustion, constant hunger, inflammation and weight gain, while the other supports stable energy and easier fat loss. Learning how carbs, fiber, protein, and fat affect glucose is more actionable than counting calories.

Simple Eating-Order And Composition Hacks Dramatically Flatten Glucose Spikes

Eating in the sequence “veggies first, then proteins and fats, starches and sugars last” can reduce a meal’s glucose spike by up to ~75% without changing what or how much you eat. A small vegetable starter (about 30% of the meal), rich in fiber, forms a viscous “shield” in the intestine that slows sugar absorption. Adding protein, fat, or extra fiber to sweets (“putting clothing on your carbs”—e.g., cake with Greek yogurt) and avoiding naked carbs like bread on an empty stomach further blunts spikes.

Savory Breakfasts Set Up A Stable Day; Sweet Breakfasts Trigger Rollercoasters

Breakfast is a key determinant of your day’s glucose pattern. Sweet breakfasts (granola, fruit juice, cereal, oats with honey/banana, pastries) create an early spike that leads to all-day rollercoasters of cravings and fatigue. Inchauspé recommends protein-centric, savory breakfasts (e.g., eggs, cheese, avocado, vegetables, some optional starch for taste) and reserving sweet foods—including “healthy” granola or smoothies—strictly as dessert after meals, not as stand-alone breakfast or snacks.

WORDS WORTH SAVING

5 quotes

If you don't have your health, you really don't have much.

Jessie Inchauspé

The more spikes you have, the faster you die.

Jessie Inchauspé

Sugar gives you pleasure; it does not give you energy.

Jessie Inchauspé

Learn the glucose hacks and then just eat everything you love.

Jessie Inchauspé

Most of us are unknowingly eating in a way that causes many of the symptoms we suffer from on a daily basis.

Jessie Inchauspé

Jessie Inchauspé’s back injury, mental health crisis, and path into biochemistryWhat glucose is, how spikes work, and why they matter for everyoneShort- and long-term consequences of glucose spikes (energy, brain, hormones, aging, disease)Mechanisms: mitochondria, insulin, insulin resistance, glycation, inflammationSugar addiction, cravings, dopamine, and why willpower isn’t the problemPractical glucose hacks: food order, savory breakfast, vinegar, movement, “clothing” your carbsDebunking nutrition myths: calories, fruit juice, “healthy” granola and sweet breakfasts

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