The Diary of a CEOThe Scary New Research On Sugar & How They Made You Addicted To It! Jessie Inchauspé | E243
At a glance
WHAT IT’S REALLY ABOUT
Glucose Spikes, Sugar Addiction, And Simple Hacks That Transform Your Health
- Biochemist and author Jessie Inchauspé (the "Glucose Goddess") explains how everyday eating patterns create harmful blood sugar spikes that quietly drive fatigue, cravings, hormonal issues, mental health struggles, and long‑term disease. She links her own severe depersonalization and panic attacks after a traumatic back injury to unstable glucose, which launched her deep dive into biochemistry and continuous glucose monitoring.
- Inchauspé dismantles common nutrition myths (calories, fruit juice, “healthy” breakfasts) and shows how glucose affects mitochondria, insulin, aging, brain function, fertility, and weight regulation even in people without diabetes. She emphasizes that our biology is mismatched with today’s ultra-processed, sugar-saturated environment.
- Most importantly, she offers practical, low-friction “glucose hacks” that let people keep eating foods they love while dramatically reducing glucose spikes—such as changing food order, adding veggie starters, choosing savory breakfasts, using vinegar, and moving after meals. The conversation blends hard science with emotional vulnerability about health, family, and the importance of learning to "fly" your own body.
- The episode positions glucose balance as a foundational lever for physical and mental health, arguing that understanding a few simple principles can cut through diet confusion, reduce shame around cravings, and help people partner with their bodies instead of fighting them.
IDEAS WORTH REMEMBERING
5 ideasGlucose Spikes Quietly Drive Everyday Symptoms And Long-Term Disease
Even without diabetes, most people experience frequent blood sugar spikes that manifest as cravings, afternoon crashes, brain fog, poor sleep, skin issues, and hormonal problems. Over years, these spikes accelerate aging (via glycation), increase inflammation, and raise risk for type 2 diabetes, heart disease, dementia/Alzheimer’s (“type 3 diabetes”), cancer, and fertility issues such as PCOS. If you feel you “could feel better,” stabilizing glucose is one of the highest-leverage starting points.
Your Body Isn’t Sabotaging You—Cravings Are Biochemical, Not Moral Failures
When you eat sugar or refined starch, your glucose rises sharply then crashes. This post-spike drop directly activates the brain’s craving centers, pushing you to seek more sugar, often starting with breakfast and persisting all day. Sugar also releases dopamine, making it behaviorally addictive. Inchauspé argues that shame and “lack of willpower” narratives are misplaced: cravings largely reflect earlier food choices and brain chemistry, not character flaws.
Think Less About Calories, More About What Food Does To Your Glucose
Calories were originally measured by literally burning food in a sealed device and seeing how much they heat water—an approach that says nothing about hormones, inflammation, or how you feel. Two 2,000-calorie diets can have radically different effects depending on glucose dynamics: one can produce exhaustion, constant hunger, inflammation and weight gain, while the other supports stable energy and easier fat loss. Learning how carbs, fiber, protein, and fat affect glucose is more actionable than counting calories.
Simple Eating-Order And Composition Hacks Dramatically Flatten Glucose Spikes
Eating in the sequence “veggies first, then proteins and fats, starches and sugars last” can reduce a meal’s glucose spike by up to ~75% without changing what or how much you eat. A small vegetable starter (about 30% of the meal), rich in fiber, forms a viscous “shield” in the intestine that slows sugar absorption. Adding protein, fat, or extra fiber to sweets (“putting clothing on your carbs”—e.g., cake with Greek yogurt) and avoiding naked carbs like bread on an empty stomach further blunts spikes.
Savory Breakfasts Set Up A Stable Day; Sweet Breakfasts Trigger Rollercoasters
Breakfast is a key determinant of your day’s glucose pattern. Sweet breakfasts (granola, fruit juice, cereal, oats with honey/banana, pastries) create an early spike that leads to all-day rollercoasters of cravings and fatigue. Inchauspé recommends protein-centric, savory breakfasts (e.g., eggs, cheese, avocado, vegetables, some optional starch for taste) and reserving sweet foods—including “healthy” granola or smoothies—strictly as dessert after meals, not as stand-alone breakfast or snacks.
WORDS WORTH SAVING
5 quotesIf you don't have your health, you really don't have much.
— Jessie Inchauspé
The more spikes you have, the faster you die.
— Jessie Inchauspé
Sugar gives you pleasure; it does not give you energy.
— Jessie Inchauspé
Learn the glucose hacks and then just eat everything you love.
— Jessie Inchauspé
Most of us are unknowingly eating in a way that causes many of the symptoms we suffer from on a daily basis.
— Jessie Inchauspé
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