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Jay Shetty PodcastJay Shetty Podcast

Dr. Will Cole ON: The Foods You ABSOLUTELY SHOULD NOT Eat To Live Longer! | Jay Shetty

Today, I sit down with Dr. Will Cole to talk about self-care. He shares the essential aspect of maintaining good physical, emotional, and mental health, the truth about eating foods that will "love you back", and how taking care of our gut…

Dr. Will ColeguestJay Shettyhost
Mar 20, 202353mWatch on YouTube

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At a glance

WHAT IT’S REALLY ABOUT

How gut health, inflammation, and shame shape what you feel

  1. Dr. Will Cole argues gut health is deeply connected to brain function, immune function, and inflammation, even when digestive symptoms aren’t obvious.
  2. He introduces “shame-flammation,” describing how stress, shame, trauma, and obsessive wellness mindsets can raise inflammation and block progress despite clean habits.
  3. He highlights four common dietary drivers that can disrupt the microbiome—gluten-containing grains, industrial seed oils, conventional dairy, and added sugar—and adds alcohol as a frequently overlooked contributor.
  4. He emphasizes patient empowerment through understanding testing options (especially more complete thyroid and hormone panels) and recognizing that standard checkups may miss root causes.
  5. He explains that food reactions can be context-dependent (e.g., SIBO and FODMAP sensitivity, histamine intolerance, mold-related sensitivities), and that many triggers can be reintroduced after addressing underlying issues.

IDEAS WORTH REMEMBERING

5 ideas

Gut health is foundational, not a niche concern.

He frames gut health as central to mood, immunity, and inflammation, emphasizing that you can have gut-driven issues even without obvious digestive symptoms.

“Common” symptoms aren’t automatically “normal.”

He describes common issues—irregular bowel movements, low energy, cravings, skin/hair changes, weight-loss resistance—as “check engine lights” that shouldn’t be dismissed just because many people have them.

Mindset can physiologically sabotage health efforts.

He defines shame-flammation as a feedback loop where stress, shame, trauma, and obsessive intention around wellness can increase inflammation and keep people stuck, even when they eat “clean.”

Dietary inflammation often clusters around a small set of frequent ingredients.

He names gluten-containing grains, industrial seed oils, conventional dairy, and added sugar as the most likely ingredients to disrupt the microbiome and raise inflammation, adding that alcohol often functions as a major overlooked disruptor.

Be an empowered patient: consider the “after plan,” not just the prescription.

He argues people should be informed about how medications like NSAIDs, antibiotics, and pain medicines can affect the gut, and then focus on supporting gut health afterward rather than ignoring downstream effects.

WORDS WORTH SAVING

5 quotes

Continually eating foods that don't love you back is like staying in a toxic relationship and wondering why you're still miserable. But avoiding foods that don't love you back isn't restrictive, it's self-respect.

— Dr. Will Cole

Just because something's common doesn't necessarily mean it's normal. Just because it's your every day doesn't mean you should settle for it.

— Dr. Will Cole

Mental health is not separate from physical health. Mental health is physical health, and our brain is a part of our body just as much as anything else is.

— Dr. Will Cole

You cannot shame your way into health, and many people try to.

— Dr. Will Cole

There's, there's no neutral food. There's no Switzerland meal.

— Dr. Will Cole

Read the available transcript
Gut-brain axis and vagus nerveInflammation and immune system links“Shame-flammation” (stress, shame, trauma)Inflammatory “core four” ingredients and alcoholMicrobiome disruption from medicationsHormones, cortisol rhythm, and thyroid testingFood sensitivities: SIBO/FODMAPs, histamines, mold-related foods

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SPEAKERS

  • Dr. Will Cole

    guest

    Functional medicine practitioner and author/host focused on gut health and inflammation.

  • Jay Shetty

    host

    Host of the On Purpose podcast and interviewer covering wellbeing and personal growth.

High quality AI-generated summary created from speaker-labeled transcript.

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