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Peter Attia MD#07 – Deep Dive: Lp(a) — what every doctor, and the 10-20% of the population at risk, needs to know
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Episode Details
EPISODE INFO
- Released
- December 22, 2019
- Duration
- 1h 16m
- Channel
- Peter Attia MD
- Watch on YouTube
- ▶ Open ↗
EPISODE DESCRIPTION
Original release date: 7/30/2018 This is our first “deep dive” episode that goes into detail on one topic. Pronounced, el-pee-little-a, this lipoprotein is simply described as a low-density lipoprotein (LDL) that has an apoprotein “a” attached to it…but Lp(a) goes far beyond its description in terms of its structure, function, and the role that it plays in cardiovascular health and disease. Affecting about 1-in-5 people, and not on the radar of many doctors, this is a deep dive into a very important subject for people to understand. We discuss: -A quick primer on lipoproteins [7:30]; -Intro to Lp(a) [11:00]; -Lab tests for Lp(a) and reference ranges [20:00]; -The physiologic functions of Lp(a) [31:00]; -The problems associated with high Lp(a) [34:15]; -Lipid-lowering therapies of Lp(a) [44:45]; -Lp(a) modification through lifestyle intervention [1:00:45]; -High LDL-P on a ketogenic/low-carb-high-fat diet [1:05:30]; and -More Show notes page: https://peterattiamd.com/lpa/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 10 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is the founder of Attia Medical, PC, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity. The practice applies nutritional biochemistry, exercise physiology, sleep physiology, techniques to increase distress tolerance, lipidology, pharmacology, and four-system endocrinology to increase lifespan (delaying the onset of chronic disease), while simultaneously improving healthspan (quality of life). Learn more: https://peterattiamd.com/ Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Play: http://bit.ly/TheDriveGooglePlay
SPEAKERS
Peter Attia
hostPhysician and host of The Peter Attia Drive, focused on longevity and preventive medicine.
EPISODE SUMMARY
In this episode of Peter Attia MD, featuring Peter Attia, #07 – Deep Dive: Lp(a) — what every doctor, and the 10-20% of the population at risk, needs to know explores peter Attia Explains Lp(a): Risks, Testing, Treatments, and What's Coming Attia describes Lp(a) as an LDL particle with an additional apolipoprotein(a) attached to its ApoB by a disulfide bond, with a structure resembling plasminogen and a variable kringle IV type 2 repeat region.
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