Skip to content
PivotPivot

Mark Cuban on Running for President as a Republican: "It Would Be SO Much Fun" | Pivot

Subscribe to Pivot! https://www.youtube.com/@pivot?sub_confirmation=1 Scott Free August continues, and Kara sits down with Mark Cuban — entrepreneur and co-founder of Cost Plus Drugs. They dig into why prescription drug prices are finally falling, Cuban's war with the healthcare industry, and Costco's surprising Medicare play. Then: why Cuban thinks chips are the new crypto, and California's controversial billionaire tax. Plus — will Cuban actually run for president? 00:00 Intro 00:58 Why RX Prices Are Falling 8:30 What’s Broken in Healthcare 15:57 Costco Gets Into Medicare 22:49 Divesting From Big Health Insurers 25:12 Are Chips the New Crypto? 33:02 Billionaires Buying Sports Teams 43:20 California’s Billionaire Tax 50:34 Turning Against Big Tech 54:39 Medicare for All? 59:34 Will Mark Cuban Run for President? 1:06:31 Predictions #pivot #podcast #karaswisher #markcuban #prescriptiondrugs #healthcare #costplusdrugs #costco #medicare #insurance #crypto #billionaire #billionaires #california #taxes #bigtech #president #2028 Producers: Lara Naaman Zoë Marcus Taylor Griffin Todd Wiseman Vox Media's Executive Producer of Podcasts: Nishat Kurwa Subscribe to Pivot on Apple Podcasts: https://podcasts.apple.com/us/podcast/pivot/id1073226719 Subscribe to Pivot on Spotify: https://open.spotify.com/show/4MU3RFGELZxPT9XHVwTNPR Follow us on Instagram and Threads at: https://www.instagram.com/pivotpodcastofficial/ Follow us on TikTok: https://www.tiktok.com/@PIVOTPODCAST Send us your questions by calling us at 855-51-PIVOT, or email pivot@voxmedia.com

Mark CubanguestKara Swisherhost
Aug 21, 20261h 9mWatch on YouTube ↗

At a glance

WHAT IT’S REALLY ABOUT

Mark Cuban targets healthcare middlemen, touts AI, discusses politics, sports

  1. Cuban credits recent prescription price declines mainly to biosimilars and increased competition, while also acknowledging Medicare drug negotiation and out-of-pocket caps as meaningful policy drivers for patients.
  2. He says PBMs and insurer conglomerates maintain high healthcare costs through opaque pricing, formulary control, and contract complexity, and he claims they pressure drugmakers not to work with Cost Plus Drugs.
  3. Cuban’s core operational advice is for self-insured employers to run healthcare/PBM contracts through LLMs (e.g., Claude/ChatGPT) to detect mismatched definitions and hidden fees, then renegotiate or switch to pass-through PBMs.
  4. He frames Costco’s Medicare move as mostly a branding/distribution play within a Medicare system still dominated by private insurers, not a structural fix to U.S. healthcare incentives.
  5. Beyond healthcare, he predicts “chips as an asset class” could become “the new crypto,” calls sports teams a vanity-plus-real-estate/streaming-driven asset, criticizes California’s billionaire tax mechanics, and says he’s more effective driving change as an entrepreneur than as a politician—though running as a Republican or independent would be “fun.”

IDEAS WORTH REMEMBERING

5 ideas

Biosimilars are the biggest near-term lever for dramatic drug price drops.

Cuban points to biosimilars for injectables (e.g., Humira/Stelara-type drugs) as the main driver of headline declines, arguing competition can collapse prices far more than incremental tweaks elsewhere.

Formulary control is PBMs’ central source of power.

He argues PBMs use formulary placement as a threat to extract rebates and to block disruptive channels like Cost Plus Drugs by warning manufacturers their entire portfolios could be penalized.

Healthcare contract opacity is a feature, not a bug.

Cuban claims pricing secrecy and 50–200 page contracts with mismatched definitions and carve-outs (e.g., “specialty” exclusions) are designed to preserve information asymmetry and protect margins.

Self-insured employers can force change faster than politicians.

Because most covered workers are in self-insured plans, he believes CEOs who audit and renegotiate contracts—or switch to pass-through PBMs—can shift industry economics without waiting for Congress.

LLMs can pay for themselves immediately via contract audits—if used carefully.

His recommended tactic is to run PBM/TPA contracts through Claude/ChatGPT to surface hidden fees and definition tricks, while stressing a competent human must verify errors or missing context.

WORDS WORTH SAVING

5 quotes

We have an economy, um, a healthcare economy, that is driven by just a few companies. You know, they, they are, the middlemen are driving up the cost of everything.

Mark Cuban

Nobody understands why there's no transparency other than Cost Plus Drugs, literally. And so if you don't understand these things, uh, it's designed to be confusing.

Mark Cuban

All I tell them they have to do is two things: run their contracts, all their healthcare contracts, through Claude or ChatGPT, and just say, "Where am I getting fucked over?"

Mark Cuban

Get the fuck out of here. Like, y- nobody is going to change their habits that run these companies unless it impacts it where they care, and that's the price of the stock.

Mark Cuban

Oh, that would be fun, though. It would be so much fun.

Mark Cuban

Why RX prices are falling (biosimilars, IRA negotiation)PBMs, formularies, and opaque rebate/fee structuresCost Plus Drugs model and PBM resistance tacticsUsing LLMs to audit employer healthcare contractsCostco-branded Medicare Advantage and private-insurer dominanceChips tokenization and “new crypto” narrativeSports team valuations, private equity, and streaming rights riskCalifornia billionaire tax feasibility and liquidity constraintsMeta/Big Tech ethics, scams, and product-liability pressuresCuban on a potential presidential run (Republican vs independent)

High quality AI-generated summary created from speaker-labeled transcript.

Get more out of YouTube videos.

High quality summaries for YouTube videos. Accurate transcripts to search & find moments. Powered by ChatGPT & Claude AI.