Dr. Dominic D'Agostino on Fasting, Ketosis, and The End of Cancer

Dr. Dominic “Dom” D’Agostino (@DominicDAgosti2) is an Assistant Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine, and a Senior Research Scientist at the Institute for Human and Machine Cognition (IHMC). He has also deadlifted 500 pounds for 10 reps after a seven-day fast. The primary focus of Dom’s laboratory is developing and testing metabolic therapies, including ketogenic diets, ketone esters and ketone supplements to induce nutritional/therapeutic ketosis. Connect with Dom D'Agostino: Like Dom D'Agostino on Facebook: https://www.facebook.com/dominic.dagostino.1 Follow Dom D'Agostino on Twitter: https://twitter.com/DominicDAgosti2 Follow Dom D'Agostino on Instagram: https://www.instagram.com/dominic.dagostino.kt Show Notes: https://tim.blog/2015/11/03/dominic-dagostino/ 00:00 Start 5:28 What Dom does 9:53 The Institutional Review Board (IRB) 12:13 Research on advanced lifters in ketosis 15:53 Can you get big and strong when in ketosis? 20:48 Defining ketones and ketosis 28:23 Preventing neurodegenerative diseases 30:48 Cachexia, sarcopenia, anabolism, and catabolism 34:48 Anabolic agents and cancer patients 38:53 The advantage of SARMS 43:23 Mimicking benefits of fasting with exogenous ketones 49:18 Accelerating the induction of ketone projection 56:13 Ketone esters 1:16:08 Benefits of eating exogenous ketones (especially in Italy) 1:20:43 The traveling ketogenic breakfast 1:25:08 Reasons for using glutamine 1:32:18 On being considered a “nutritionist” 1:41:38 Metformin and cancer survival rates 1:46:18 What Dom would do if he had cancer 2:03:03 Thoughts on therapeutic fasting 2:08:23 Observations of people who experiment with fasting 2:14:33 Risks of consuming a cocktail of exogenous ketones 2:22:45 Foods and beverages that spike ketone levels 2:41:33 Top resources 2:43:13 Most gifted books 2:50:18 Fighting Lyme Disease with the ketogenic diet 2:53:18 The effect of ketosis on mitochondria 2:55:53 Healing from use of antibiotics SUBSCRIBE: http://bit.ly/1dSzTkW About Tim Ferriss: Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 200 million downloads and been selected for “Best of iTunes” three years running. Connect with Tim Ferriss: Visit the Tim Ferriss PODCAST: https://bit.ly/2rYjUBr Visit the Tim Ferriss BLOG: http://bit.ly/17jDHw3 Like Tim Ferriss on FACEBOOK: http://on.fb.me/1avYUxq Follow Tim Ferriss on TWITTER: http://bit.ly/17d94TE Follow Tim Ferriss on INSTAGRAM: http://bit.ly/2IfH37J Follow Tim Ferriss on INSTAGRAM: http://bit.ly/2IfH37J

Tim FerrisshostDr. Dominic D'Agostinoguest

Nov 20, 20153h 6mWatch on YouTube ↗

EPISODE INFO

Released: November 20, 2015
Duration: 3h 6m
Channel: Tim Ferriss
Watch on YouTube: ▶ Open ↗

EPISODE DESCRIPTION

Dr. Dominic “Dom” D’Agostino (@DominicDAgosti2) is an Assistant Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine, and a Senior Research Scientist at the Institute for Human and Machine Cognition (IHMC). He has also deadlifted 500 pounds for 10 reps after a seven-day fast. The primary focus of Dom’s laboratory is developing and testing metabolic therapies, including ketogenic diets, ketone esters and ketone supplements to induce nutritional/therapeutic ketosis. Connect with Dom D'Agostino: Like Dom D'Agostino on Facebook: https://www.facebook.com/dominic.dagostino.1 Follow Dom D'Agostino on Twitter: https://twitter.com/DominicDAgosti2 Follow Dom D'Agostino on Instagram: https://www.instagram.com/dominic.dagostino.kt Show Notes: https://tim.blog/2015/11/03/dominic-dagostino/ 00:00 Start 5:28 What Dom does 9:53 The Institutional Review Board (IRB) 12:13 Research on advanced lifters in ketosis 15:53 Can you get big and strong when in ketosis? 20:48 Defining ketones and ketosis 28:23 Preventing neurodegenerative diseases 30:48 Cachexia, sarcopenia, anabolism, and catabolism 34:48 Anabolic agents and cancer patients 38:53 The advantage of SARMS 43:23 Mimicking benefits of fasting with exogenous ketones 49:18 Accelerating the induction of ketone projection 56:13 Ketone esters 1:16:08 Benefits of eating exogenous ketones (especially in Italy) 1:20:43 The traveling ketogenic breakfast 1:25:08 Reasons for using glutamine 1:32:18 On being considered a “nutritionist” 1:41:38 Metformin and cancer survival rates 1:46:18 What Dom would do if he had cancer 2:03:03 Thoughts on therapeutic fasting 2:08:23 Observations of people who experiment with fasting 2:14:33 Risks of consuming a cocktail of exogenous ketones 2:22:45 Foods and beverages that spike ketone levels 2:41:33 Top resources 2:43:13 Most gifted books 2:50:18 Fighting Lyme Disease with the ketogenic diet 2:53:18 The effect of ketosis on mitochondria 2:55:53 Healing from use of antibiotics SUBSCRIBE: http://bit.ly/1dSzTkW About Tim Ferriss: Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 200 million downloads and been selected for “Best of iTunes” three years running. Connect with Tim Ferriss: Visit the Tim Ferriss PODCAST: https://bit.ly/2rYjUBr Visit the Tim Ferriss BLOG: http://bit.ly/17jDHw3 Like Tim Ferriss on FACEBOOK: http://on.fb.me/1avYUxq Follow Tim Ferriss on TWITTER: http://bit.ly/17d94TE Follow Tim Ferriss on INSTAGRAM: http://bit.ly/2IfH37J Follow Tim Ferriss on INSTAGRAM: http://bit.ly/2IfH37J

SPEAKERS

Tim Ferriss
host
Entrepreneur and author, host of The Tim Ferriss Show.
Dr. Dominic D'Agostino
guest
Research scientist focused on fasting, nutritional ketosis, and metabolic-based approaches to health and disease.

EPISODE SUMMARY

In this episode of Tim Ferriss, featuring Tim Ferriss and Dr. Dominic D'Agostino, Dr. Dominic D'Agostino on Fasting, Ketosis, and The End of Cancer explores dom D’Agostino explains ketosis, exogenous ketones, and metabolic cancer strategies Dr. Dominic D’Agostino explains what ketosis and ketone bodies are, how fasting and ketogenic diets produce them, and why he sees ketones as both fuels and signaling molecules.

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